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Original Article

Ionic Binding Characteristics of Monoclonal Autoantibodies to DNA from NZB.H-2bm12 Mice

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Pages 301-309 | Received 13 Dec 1990, Accepted 30 Jan 1991, Published online: 07 Jul 2009

References

  • Theofilopoulos A N, Dixon F J. Murine models of systemic lupus erythematosus. Adv Immunol. 1985; 37: 269–390
  • Datta S K. A search for the underlying mechanisms of systemic autoimmune disease in the NZB x SWR model. Clin Immunol Immunopath. 1989; 51: 142–156
  • Kastner D L, Steinberg A D. Determinants of B cell hyperactivity in murine lupus. Concepts in Immunopathol. 1988; 6: 22–88
  • Steinberg A D, Huston D P, Taurog J D, Cowdery J S, Raveche E S. The cellular and genetic basis of murine lupus. Immunol Rev. 1981; 55: 121–154
  • Kohno A, Yoshida H, Sekita K, Maruyama N, Ozaki S, Hirose S, et al. Genetic regulation of the class conversion of dsDNA‐specific antibodies in (NZB × NZW) FI hybrids. Immunogenetics. 1983; 18: 513–524
  • Dang H, Harbeck R J. The in vivo and in vitro glomerular deposition of isolated anti‐double‐stranded‐DNA antibodies in NZB/W mice. Clin Immunol Immunopathol. 1984; 30: 265–278
  • Morgan A, Buchanan R, Lew A, Olsen I, Staines N. Five groups of antigenic determinants on DNA identified by monoclonal antibodies from (NZB × NZW) FI and MRL/Mp‐lpr/lpr mice. Immunology. 1985; 55: 75–83
  • Eilat D, Hochberg M, Pumphrey J, Rudikoff S. Monoclonal antibodies to DNA and RNA from NZB/NZW F1 mice: antigenic specificities and NH2, terminal amino acid sequences. J Immunol. 1984; 133: 489–494
  • Jacob L, Tron F. Monoclonal anti‐deoxyribonucleic acid antibodies. I. Isotype and specificity studies. J Immunol. 1982; 128: 895–898
  • Yoshida H, Yoshida M, Izui S, Lambert P H. Distinct clono‐types of anti‐DNA antibodies in mice with lupus nephritis. J Clin Invest. 1985; 76: 685–694
  • Hirose S, Nagasawa R, Sekikawa I, Hamaoki M, Ishida Y. Enhancing effect of H‐2 linked gene(s) on the autoimmune traits of (NZB × NZW) FI mice. J Exp Med. 1984; 158: 228–233
  • Kotzin B L, Palmer E. The contribution of NZW genes to lupus‐like disease in (NZB × NZW) FI mice. J Exp Med. 1987; 165: 1237–1251
  • Chiang B ‐L, Bearer E, Ansari A, Dorshkind K, Gershwin M E. Autoantibodies in NZB‐H‐2bm12 mice. J Immunol. 1990; 145: 94–101
  • Schiffenbauer J, McCarthy D M, Nygaard N R, Woolfe S L, Didier D K, Schwarz B D. A unique sequence of the NZW I‐E β chain and its possible contribution to autoimmunity in the (NZB × NZW)F1 mouse. J Exp Med. 1989; 170: 971–984
  • Schroer J A, Inman J K, Thomas J W, Rosenthal A S. H‐2 linked Ir gene control of antibody response to insulin. 1. Anti‐insulin plaque‐forming cell primary responses. J Immunol. 1979; 123: 670–675
  • de St Groth S F, Scheidegger D. Production of monoclonal antibodies. Strategy and tactics. J Immunol Meth. 1980; 35: 1–21
  • Rubin R L, Joslin F G, Tan E M. An improved ELISA for anti‐native DNA by elimination of interference by anti‐histone antibodies. J Immunol Meth. 1983; 63: 359–366
  • Ebling F, Hahn B H. Restricted subpopulations of DNA antibodies in kidneys of mice with systemic lupus. Arth Rheum. 1980; 23: 392–403
  • Lafer E M, Rauch J, Andrzejewski C, Jr, Mudd D, Furie B, Schwarz R S, et al. Polyspecific monoclonal lupus autoantibodies reactive with both polynucleotides and phospholipids. J Exp Med. 1981; 153: 897–909
  • Diamond B, Scharff M D. Somatic mutation of the TI5 heavy chain gives rise to an antibody with autoantibody specificity. Proc Natl Acad Sci. 1984; 81: 5841–5844
  • Meggio F, Penna L A. Phosphorylation of phosvitin by casein kinase‐2 provides the evidence that phosphoserines can replace carboxylic amino acids as specificity determinants. Biochim Biophys Acta. 1988; 971: 227–231
  • Sabbaga J, Pankewycz O G, Lufft V, Schwartz R S, Madaio M P. Cross‐reactivity distinguishes serum and nephritogenic anti‐DNA antibodies in human lupus from their natural counterparts in normal serum. J Autoimmun. 1990; 3: 215–235
  • Pankewycz O G, Migliorini P, Madaio M P. Polyreactive autoantibodies are nephritogenic in murine lupus nephritis. J Immunol. 1987; 139: 3287–3294
  • Gavalchin J, Datta S K. Autoantibodies deposited in renal, lesions show a distinctive and restricted idiotypic diversity. J Immunol. 1987; 138: 138–148
  • Koike T, Nagasawa R, Nagata N, Shirai T. Specificity of mouse hybridoma antibodies to DNA. Immunology Letts. 1982; 4: 93–97
  • Klotz J L, Kiser G C, Kronenberg M. Molecular and serological diversity of anti‐DNA autoantibodies from NZB and NZB × NZW F1 mice. Immunol Letts. 1988; 19: 341–350
  • Pohl F M, Jovin T M. Salt‐induced co‐operative conformational change of a Synthetic DNA: Equilibrium and kinetic studies with poly (dG‐dC). J Mol Biol. 1972; 67: 375–396
  • Hamaguchi K, Geiduschek E P. The effect of electrolytes on the stability of the deoxyribonucleate helix. J Amer Chem Soc. 1962; 84: 1329–1338
  • Aotsuka S, Funahashi T, Tani N, Okawa‐Takatsuji M, Kinoshita M, Yokohari R. Adsorption of anti‐DNA antibodies by immobilized and polyanionic compounds. Clin Exp Immunol. 1990; 79: 215–220
  • Isenberg D, Williams W, Axford J, Bakimer R, Bell D, et al. Comparison of DNA antibody idiotypes in human sera: an international collaborative study of 19 idiotypes from 11 different laboratories. J Autoimmunity. 1990; 3: 393–414
  • Dohlman J, Brendel V, Karlin S. Association of concentration charge with the nuclear autoantigens. Arth Rheum. 1990; 33: S33

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