12
Views
29
CrossRef citations to date
0
Altmetric
Original Article

Coxsackievirus B4-Induced Development of Antibodies to 64,000-Mr Islet Autoantigen and Hyperglycemia in Mice

, &
Pages 49-56 | Accepted 19 Apr 1991, Published online: 07 Jul 2009

References

  • Rossini A A, Mordes J P, Like A A. Immunology of insulin‐dependent diabetes mellitus. Ann Rev Immunol. 1985; 3: 289–320
  • Bottazzo G F, Todd I, Mirakian R, Belfiore A, Pujol‐Borrell R. Organ‐specific autoimmunity: a 1986 overview. Immunol Rev. 1986; 94: 137–169
  • Eisenbarth G S. Type I diabetes mellitus: a chronic autoimmune disease. N Engl J Med. 1986; 314: 1360–1368
  • Lernmark Å, Li S, Baekkeskov S, Christie M, Michelson B. Islet‐specific immune mechanisms. Diubetes/Metabolism Rev. 1987; 3: 959–980
  • Baekkeskov S, Nielsen J H, Manner B, Bilde T, Ludvigsson J, Lernmark Å. Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins. Natur, (Lond). 1982; 298: 167–169
  • Baekkeskov S, Landin M, Kristensen J K, et al. Antibodies to n 64,000 Mr human islet cell antigen precede the clinical onset of insulin‐dependent diabetes. J Clin Invest. 1987; 79: 926–934
  • Baekkeskov S, Warnock G, Christie M, Rajotte R V, Larsen P M, Fey S. Revelation of specificity of 64 K autoantibodies in IDDM serums by high‐resolution 2‐D gel electrophoresis. Diabetes. 1989; 38: 1133–1141
  • Kampe O, Anderson A, Bjork E, Hallberg A, Karlsson A. High‐glucose stimulation of 64,000 Mr islet cell autoantigen expression. Diabetes. 1989; 38: 1326–1328
  • Baekkeskov S T, Dyrberg T, Lernmark Å. Autoantibodies to a 64‐kilodalton islet cell protein precede the onset of spontaneous diabetes in the BB rat. Science 1984; 224: 1348–1350
  • Atkinson M A, Maclaren N K. Autoantibodies in nonobese diabetic mice immunoprecipitate 64,000‐M, islet antigen. Diabetes. 1988; 37: 1587–1590
  • Christie M R, Pipeleers D, Lernmark A, Baekkeskov S. Cellular specificity of the 64 K islet antigen in type I diabetes (Abstract). Diabetes. 1988; 37: 5A, (Suppl.)
  • Webb S R, Loria R M, Madge G E, Kibrick S. Susceptibility of mice to group B Coxsackieviruses is influenced by the diabetic gene. J Exp Med. 1976; 143: 1239–1248
  • Yoon J W, Austin M, Onodera T, Notkins A L. Virus‐induced diabetes mellitus: Isolation of a virus from the pancreas of a child with diabetic ketoacidosis. N Engl J Med. 1979; 300: 1173–1179
  • Kibrick S, Benirschke K. Severe generalized disease (encephalohepatomyocarditis) occurring in the newborn period and due to infection with Coxsackievirus group B. Pediatrics. 1958; 22: 857–875
  • Hartig P C, Madge G E, Webb S R. Diversity within a human isolate of Coxsackie B4: relationship to viral‐induced diabetes. J Med Virol., 11: 23–30
  • Chatterjee N K, Haley T M, Nejman C. Functional alterations in pancreatic B cells as a factor in virus‐induced hyperglycemia in mice. J Biol Chem., 260: 12786–12791
  • Chatterjee N K, Nejman C. Insulin mRNA content in pancreatic beta cells of coxsackievirus B4‐induced diabetic mice. Mol Cell Endocrinol. 1988; 55: 193–202
  • Gerling I, Nejman C, Chatterjee N K. Effect of coxsackievirus B4 infection in mice on expression of 64,000‐M, autoantigen and glucose sensitivity of islets before development of hyperglycemia. Diabetes. 1988; 37: 1419–1425
  • Gerling I, Baekkeskov S, Lernmark A. Islet cell and 64 K autoantibodies are associated with plasma IgG in newly diagnosed insulin‐dependent diabetic children. J Immunol. 1986; 137: 3782–3785
  • Chatterjee N K, Tuchowski C. Comparison of capsid polypeptides of group B coxsackieviruses and polypeptide synthesis in infected cells. Arch Virol. 1981; 70: 255–269
  • Yoon J W, Onodera T, Notkins A L. Virus‐induced diabetes mellitus. X. V. Beta cell damage and insulin‐dependent hyperglycemia in mice infected with coxsackie virus B4. J Exp Med. 1978; 148: 1068–1080
  • Cook S A, Loria R M, Madge G E. Host factors in coxsackievirus B4‐induced pancreopathy. J Lab Invest. 1982; 46: 377–383
  • Loria R M, Montgomery L B, Tuttle‐Fuller N, Gregg H M. Influence of diabetes mellitus heridity is associated with impaired immunity to coxsackievirus 84. Diabetes Res Clin Pract. 1986; 2: 91–96
  • Wolfgram L J, Rose N R. Coxsackievirus infection as a trigger of cardiac autoimmunity. Immunol Res. 1989; 8: 61–80
  • Yale J F, Grose M, Seemayer T A, Marliss E B. Diabetes prevention in BB rats by frequent blood withdrawal started at a young age. Diabetes. 1988; 37: 327–333
  • Like A A, Rossini A A, Guberski D L, Appel M C. Spontaneous diabetes mellitus reversal and prevention in the BB/W rat with antiserum to rat lymphocytes. Science 1979; 206: 1421–1423
  • Rossini A A, Salvin S, Woda B A, Geisberg M, Like A A, Mordes J P. Total lymphoid irradiation prevents diabetes mellitus in the Bio/Breeding/Worcester (BB/W) rat. Diabetes. 1984; 33: 543–541
  • Laupacis A, Gardell C, Dupre J, Stiller C R, et al. Cyclosporin prevents diabetes in BB Wistar rats. 1983. Lancer. 1983; 1: 10–11
  • Naji A, Silvers W K, Kimura H, Anderson A O, Barker C F. Influence of islets and bone marrow transplantation on the diabetes and immunodeficiency of BB rats. Metab Clin Exp. 1983; 32(Suppl. I)62
  • Handler E S, Mordes J P, Nakamura N, Rossini A A. Prevention of spontaneous diabetes in the BB/W rat by Wistar Furth (WF) spleen cells sequestered in diffusion chambers (Abstract). Diabetes. 1986; 35(Suppl. 1)75A
  • Dyrberg T, Nakhooda A F, Baekkeskov S, Lernmark Å, Poussier P, Marliss E B. Islet cell surface antibodies and lymphocyte antibodies in the spontaneously diabetic BB Wistar rat. Diabetes. 1982; 31: 278–281

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.