13
Views
38
CrossRef citations to date
0
Altmetric
Original Article

A New Murine Model of Autoimmune Orchitis Induced by Immunization With Viable Syngeneic Testicular Germ Cells Alone.: II. Immunohistochemical Findings of Fully-Developed Inflammatory Lesion

, , , &
Pages 89-97 | Received 30 Apr 1991, Published online: 07 Jul 2009

References

  • Bernard C CA, Mitchell G F, Leydon J, Bargerbos A. Experimental autoimmune orchitis in T-cell-deficient mice. Int Archs Allergy appl Immun 1978; 56: 256–263
  • Mahi-Brown C A, Yule T D, Tung K SK. Adoptive transfer of murine autoimmune orchitis to naive recipients with immune lymphocytes. Cell Immunol 1987; 106: 408–419
  • Mahi-Brown C A, Tung K SK. Activation requirements of donor T cells and host T cell recruitment in adoptive transfer of murine experimental autoimmune orchitis (EAO). Cell Immunol 1989; 124: 368–379
  • Itoh M, Hiramine C, Hojo K. A new murine model of autoimmune orchitis induced by immunization with viable syngeneic testicular germ cells alone. I. Immunological and histological studies. din exp Immunol 1991; 83: 137–142
  • Traugott U, Raine C S, McFarlin DE. Acute experimental allergic encephalomyelitis in the mouse: Immunopathology of the developing lesion. Cell Immunol 1985; 91: 240–254
  • Sobel R A, Blanchette B W, Bhan A K, Colvin RB. The immuno-pathology of experimental allergic encephalomyelitis. I. Quantitation analysis of inflammatory cells in situ. J Immunol 1984; 132: 2393–2401
  • Creemers P, Giraldo A A, Rose N R, Kong YM. T-cell subsets in the thyroids of mice developing autoimmune thyroiditis. Cell Immunol 1984; 87: 692–697
  • Cohen S B, Dijkstra C D, Weetman AP. Sequential analysis of experimental autoimmune thyroiditis induced by neonatal thymectomy in the Buffalo strain rat. Cell Immunol 1988; 114: 126–136
  • De Assis-Paiva H J, Rayner D C, Roitt I M, Cooke A. Cellular infiltration in induced rat thyroiditis: phenotypic analysis and relationship to genetic restriction. Clin exp Immunol 1989; 75: 106–112
  • Yule T D, Montoya G D, Russell L D, Williams T M, Tung K SK. Autoantigenic germ cells exist outside the blood testis barrier. J Immunol 1988; 141: 1161–1167
  • Taguchi O, Nishizuka Y. Experimental autoimmune orchitis after neonatal thymectomy in the mouse. Clin exp Immunol 1981; 46: 425–434
  • Tung K SK, Yule T D, Mahi-Brown C A, Listrom MB. Distribution of histopathology and la positive cells in actively induced and passively transferred experimental autoimmune orchitis. J Immunol 1987; 138: 752–759
  • Born W, Wekerle H. Leydig cells nonspecifically suppress lymphoproliferation in vitro: Implication for the testis as an immunologically privileged site. Am J Reprod Immunol 1982; 2: 291–295
  • Anderson D J, Tarter TH. Immunosuppressive effects of mouse seminal plasma components in vivo and in vitro. J Immunol 1982; 128: 535–539
  • Wyatt C R, Law L, Magnuson J A, Griswold M D, Magnuson NS. Suppression of lymphocyte proliferation by proteins secreted by cultured Sertoli cells. J Reprod Immunol 1988; 14: 27–40
  • Pollanen P, Soder O, Uksila J. Testicular immunosuppressive protein. J Reprod Immunol 1988; 14: 125–128
  • Whitmore I WF, II., Karsh L, Gittes RF. The role of germinal epithelium and spermatogenesis in the privileged survival of intratesticular grafts. J Urol 1985; 134: 782–786
  • El-Dermry M I, Elton R, Hargreave T B, James K, Busuttil A, Chisholm GD. Immunocompetent cells in human testis in health and disease. Fenil Steril 1987; 48: 470–479
  • Pollanan P, Niemi M. Immunohistochemical identification of macrophages, lymphoid cells and HLA antigens in the human testis. Int J Androl 1987; 10: 37–42
  • Michlkiewicz W, Mietkiewski K, Rveki T, Warchol JB. Immunohistochemical investigations of the testis in certain kinds of sterility in man. Fol Histoch Cytochem 1971; 9: 277–282
  • Jodot-Van De Casseye M, De Bled G, Schoysman R. An immunohistochemical study for testicular biopsies in cases of male infertility. Andrologia 1980; 12: 122–129
  • Salmon F, Saremaslani P, Jakob M, Hedinger CE. Immune complex orchitis in infertile men. Immunoelectron microscopy of abnormal basement membrane structures. Lab Invest 1982; 47: 555–567
  • Lehmann D, Temminck B, Da Runga D, Leibundgut B, Sulmoni A, Muller H. Role of immunological factors in male infertility. Lab Invest 1987; 57: 21–28
  • Hiramine C, Hojo K. Requirement of B lymphocytes in local adoptive transfer of experimental allergic orchitis (EAO) by lymph node cells. Am J Reprod Immunol 1984; 6: 85–91
  • Cross N L, Moore S. Regional binding of human anti-sperm antibodies assessed by indirect immunofluorescence. Hum Reprod 1990; 5: 47–51
  • Haas GO, Jr., DeBault L E, D'Cruz O J, Shuey R. The effect of fixatives and/or air-drying on the plasma and acrosomal membranes of human sperm. Fenil Steril 1988; 50: 487–492
  • Haas GG, Jr., D'Cruz O J, De Bault LE. Distribution of human leukocyte antigen-ABC and-D/DR antigens in the unfixed human testis. Am J Reprod Immunol 1988; 18: 47–51
  • Johnson MH. An immunologic barrier in the guinea-pig testis. J Pathol 1970; 101: 129–139

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.