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Original Article

Antibodies Against Central Nervous System Tissue (Anti-Cns) Detected by Elisa and Western Blotting: Marker Antibodies for Neuropsychiatric Manifestations in Connective Tissue Diseases

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Pages 133-144 | Received 25 Feb 1991, Published online: 07 Jul 2009

References

  • Dubois E L, Tuffanelli DL. Clinical manifestations of systemic lupus erythematosus. Computer analysis of 520 cases. JAMA 1964; 190: 104–111
  • Ellis S G, Verity MA. The central nervous system involvement in systemic lupus erythematosus. A review of neuropathologic findings in 57 cases, 1955–1977. Semin Arthr Rheum 1979; 8: 212–221
  • Klippel H, Zvaifler N J. Neuropsychiatric abnormalities in systemic lupus erythematosus. Clin Rheum Dis 1975; 1: 621–638
  • Feinglass E J, Arnett F C, Dorset) CA, Zizic T M, Stevens MB. Neuropsychiatric manifestations of systemic lupus erythematosus: diagnosis, clinical spectrum, and relationship to other features of the disease. Medicine 1976; 55: 323–339
  • Gibson T, Mayers AR. Nervous system involvement in systemic lupus erythematosus. Ann Rheum Dis 1976; 35: 398–406
  • Grigor R, Edmonds J, Lewkonia R, Breshnihan B, Hughes G RV. Systemic lupus erythematosus: a prospective analysis. Ann Rheum Dis 1978; 37: 121–128
  • Cohen S B, Hurd ER. Neurological complications of connective tissue and other “collagen-vascular” diseases. Semin Arthritis Rheum 1980; 11: 190–212
  • Hughes G RV. Central nervous system lupus—diagnosis and treatment. J Rheumatol 1980; 7: 405–411
  • How A, Dent P B, Liao S-K, Denburg JA. Antineural antibodies in neuropsychiatric systemic lupus erythematosus. Arthritis Rheum 1985; 28: 789–795
  • Tsokos G C, Tsokos M, Le Riche N GH, Klippel JH. A clinical and pathologic study of cerebrovascular disease in patients with systemic lupus erythematosus. Sem Arth Rheum 1986; 16: 70–78
  • Stoltze C A, Hanlon D G, Pease G L, Henderson JW. Keratoconjunctivitis sicca and Sjögren's syndrome. Arch Intern Med 1969; 106: 513–521
  • Alexander G E, Provost T T, Stevens M B, Alexander EL. Sjögren's syndrome: central nervous system manifestations. Neurology 1982; 31: 1391–1396
  • Malinow K L, Molina R, Gordon B. Neuropsychiatric dysfunction in primary Sjögren's syndrome. Ann Int Med 1985; 103: 344–349
  • Alexander E L, Beall S S, Gordon G, Seines O A, Yannakakis G D, Patronas N, Provost T T, McFarland HF. Magnetic resonance imaging of cerebral lesions in patients with the Sjögren's syndrome. Ann Int Med 1988; 108: 815–823
  • Bluestein H G, Zvaifler NJ. Brain-reactive lymphocytotoxic antibodies in the serum of patients with systemic lupus erythematosus. J Clin Invest 1976; 57: 509–516
  • Breshnihan B, Oliver M, Grigor M, Hughes G RV. Brain reactivity of lymphocytotoxic antibodies in systemic lupus erythematosus with and without cerebral involvement. Clin Exp Immunol 1977; 30: 333–337
  • Williams G W, Bluestein H G, Steinberg AD. Brain-reactive lymphocytotoxic antibodies in the cerebrospinal fluid of patients with systemic lupus erythematosus: correlation with central nervous system involvement. Clin Immunol Immunopathol 1981; 18: 126–132
  • Tcmesvari P, Denburg J, Denbrug S. Serum lymphocytotoxic antibodies in neuropsychiatric lupus: a serial study. Clin Immunol Immunopathol 1983; 28: 243–251
  • Robbins M L, Kornguth S E, Bell C L, Kalinke T, England D, Turski P, Graziano FM. Antineurofilament antibody evaluation in neuropsychiatric systemic lupus erythematosus. Arthritis Rheum 1988; 31: 623–631
  • Bluestein H G, Williams G W, Steinberg AD. Cerebrospinal fluid antibodies to the neuronal cells: association with neuropsychiatric manifestations of systemic lupus erythematosus. Am J Med 1981; 70: 240–246
  • Toh B H, Mackay IR. Autoanlibody to a novel neuronal antigen in systemic lupus erythematosus and in normal human sera. Clin Exp Immunol 1981; 44: 555–559
  • Bonfa E, Golombek S J, Kaufman L D. Association between lupus psychosis and anti-ribosomal P protein antibodies. N Engl J Med 1987; 317: 265–271
  • Tan E M, Cohen A S, Fries J F. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982; 25: 1271–1277
  • Tan EM. Antinuclear antibodies: Diagnostic markers for autoimmune diseases and probes for cell biology. Adv Immunol 1989; 44: 93–149
  • Subcommittee for scleroderma criteria of the American rheumatism association diagnostic and therapeutic criteria committee: preliminary criteria for the classificalion of systemic sclerosis (scleroderma). Arthritis Rheum 1980; 23: 581–590
  • Fox R I, Gowell F V, Bone R C, Michelson PE. Primary Sjögren's syndrome: clinical and immunopathologic features. Semin Arthritis Rheum 1980; 14: 77–105
  • Fox R I, Robinson C A, Curd J G. Sjögren's syndrome. Proposed criteria for classification. Arthritis Rheum 1986; 29: 577–585
  • Kassan S S, Lockshin MD. Central nervous systemic lupus erythematosus: the need for classification. Arthritis Rheum 1979; 22: 1382–1385
  • Lai J CK, Clark JB. Preparation of synaptic and nonsynaptic mitochondria from mammalian brain. Methods Enzymol 1979; 55: 51–60
  • Berg P A, Doniach D, Roitt IM. Mitochondrial antibodies in primary biliary cirrhosis. I. Localization of the antigen to mitochondrial membranes. J Exp Med 1967; 126: 277–290
  • Kurata N, Tan EM. Identification of antibodies to nuclear acidic antigens by counterimmunoelectrophoresis. Arthritis Rheum 1976; 19: 574–580
  • Venables P JW, Smith R R, Maini RN. Purification and characterization of the Sjögren's syndrome A and B antigens. Clin Exp Immunol 1983; 54: 731–738
  • Berg P A, Klein R. Heterogeneity of antimitochondrial antibodies. Sem Liver Dis 1989; 9: 103–116
  • Rizzetto M, Swana G, Doniach D. Microsomal antibodies in chronic active hepatitis and other disorders. Clin Exp Immunol 1973; 15: 331–339
  • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Annul Biochem 1976; 72: 248–254
  • Engvall E. Enzyme immunoassay ELISA and EMIT. Meth Enzymol 1980; 70: 419–439
  • Klein R, Berg PA. Characterization of a new mitochondrial antigen-antibody system (M9/anti-M9) in patients with anti-M2 positive and anti-M2 negative primary biliary cirrhosis. Clin Exp Immunol 1990; 81: 65–71
  • Laemmli U. Cleavage of structural proteins during assembly of the head of bacteriophage T4. Nature 1970; 277: 680–685
  • Towbin H, Staehelin T, Gordon J. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci USA 1979; 76: 4350–4354
  • Aarden L A, DeGroot E R, Feltkamp T EW. Immunology of DNA. III. Crithidia luciliae, a simple substrate for the determination of anti-dsDNA with the immunofluorescence technique. Ann NY Acad Sci 1975; 254: 505–515
  • Tan E M, Kunkel HG. Characteristics of a soluble nuclear antigen precipitation with sera of patients with systemic lupus erythematosus. J Immunol 1966; 96: 464
  • Knight JG. Dopamine-receptor stimulating autoantibodies: a possible cause of schizophrenia. Lancet 1982; ii: 1073–1076
  • Harris E N, Gharavi A E, Hughes G RV. Anti-phospholipid antibodies. Clinics Rheum Dis 1985; 11: 591–609
  • Love P E, Santoro AS. Antiphospholipid antibodies: anticardiolipin and the lupus anticoagulant in systemic lupus erythematosus (SLE) and in non-SLE disorders. Ann Int Med 1990; 112: 682–698

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