References
- Jerne NK. Towards a network theory of the immune system. Ann Immunol (Inst Pasteur) 1984; 125C: 327–389
- Chen P P, Liu M F, Sinha S, Carson D. A 16/6 idiotype-positive anti-DNA antibody is encoded by a conserved VH gene with no somatic mutation. Arth Rheum 1988; 32: 1429–1431
- Chen P P, Liu M L, Glass C A, Sinha S, Kipps T J, Carson DA. Characterization of two immunoglobulin VH genes that are homologous to human rheumatoid factors. Arth Rheum 1989; 32: 12–76
- Sanz I, Dan H, Takei M, Talal N, Capra JD. VH-sequence of a human anti-Sm autoantibody: Evidence that autoantibodies can be unmutated copies of germline genes. J Immunol 1989; 142: 883–887
- Zanetti M, DeBaets M, Rogers J. High degree of idiotypic cross-reactivity among murine monoclonal antibodies to thyroglobulin. J Immunol 1983; 131: 2452–2457
- Horsfall A C, Isenberg DA. Idiotypes and autoimmunity: a review of their role in human disease. J Autoimmun 1988; 1: 7–30
- Zanetti M. Self-immunity and the autoimmune network. A molecular perspective to ontogeny and regulation of the immune system. Ann Immunol (Inst. Pasteur) 1988; 139: 619–631
- Moroi Y, Peebles C, Fritzler M J, Steigerwald J, Tan EM. Autoantibody to centromere (kinetochor) in scleroderma sera. Proc Natl Acad Sci USA 1980; 77: 1627–1631
- Tan E M, Rodnan G P, Garcia I, Moroi Y, Fritzler M J, Peebles C. Diversity of antinuclear antibodies in progressive systemic sclerosis: Anticentromere antibody and its relationship to CREST-syndrome. Arth Rheum 1980; 23: 617–625
- Fritzler M J, Kinsella T D, The C RE. ST syndrome: a distinct serologic entity with anticentromere antibodies. Am J Med 1980; 69: 520–526
- Tuffdnelli D L, McKeon F, Leinsmith D AM, Burnham Th K, Kirschner M. Anticentromere and anticentriole antibodies in the scleroderma spectrum. Arch Dermatol 1983; 119: 560–566
- Steen VD, Ziegler G L, Rodnan G P, Medsger ThA. Clinical and laboratory associations of anticentromere antibody in patients with progressive sclerosis. Arth Rheum 1984; 27: 125–131
- Sarkozi J, Bookman A MM, Lee P, Leystone E C, Fritzler MJ. Significance of anticentromere antibody in idiopathic Raynaud's syndrome. Am J of Med 1987; 83: 893–898
- Steen V D, Powell D L, Medsger ThA. Clinical correlations and prognosis based on serum autoantibodies in patients with systemic sclerosis. Arth Rheum 1988; 31: 196–203
- Weiner E S, Earnshaw W C, Senecal J L, Bordwell B, Johnson P, Rothfield NF. Clinical applications of anticentromere antibodies and antibodies to toposiomerase I: a study of 355 patients. Arth Rheum 1988; 31: 378–385
- McNeilage L J, Youngchiyud U, Whittingham S. Racial differences in antinuclear antibody patterns and clinical manifestations of scleroderma. Arth Rheum 1989; 32: 54–60
- Giordano M, Valentini G, Migliaresi S, Picillo U, Vatti M. Different antibody patterns and different prognoses in patients with scleroderma with various extent of skin sclerosis. J Rheumatol 1986; 13: 911–916
- Tramposch H D, Smith D C, Senecal J L, Rothfield N. A longterm longitudinal study of anticentromere antibodies. Arth Rheum 1984; 27: 121–124
- Earnshaw W C, Rothfield N F. Identification of a family of human centromere proteins using autoimmune sera from patients with scleroderma. Chromosoma 1985; 91: 313–321
- Earnshaw W C, Bordwell B, Marino C, Rothfield NF. Three human chromosomal autoantigens are recognized by sera from patients with anticentromere antibodies. J Clin Invest 1986; 77: 426–430
- Earnshaw W C, Sullivan K F, Machlin P S, Cooke C A, Kaiser D A, Pollard ThD. Molecular cloning of cDNA for CENP-B, the major human centromere autoantigen. J Cell Biol 1987; 104: 817–829
- Eisenberg R A, Earnshaw W C, Bordwell B J, Craven S Y, Rothfield NF. Isotype analysis of the anti-CENF-B (anticentromere) autoantibody: Evidence for restricted clonality. Arthr Rheum 1989; 32: 1315–1318
- McHugh N J, James I E, Maddison PJ. Differential isotype recognition of two centromere associated polypeptides by immunoblotting in connective tissue disease. Clin Exp Immunol 1988; 72: 457–464
- Bona C A, Kohler H. Anti-idiotypic antibodies and internal images. Monoclonal and Anti-Idiotypic Antibodies: Probes for Receptor Structure and Function. Alan R. Liss, Inc., New York 1984; 141–149
- Rothfield N, Whitaker D, Bordwell B, Weiner E, Senecal J L, Earnshaw Wc. Detection of anticentromere antibodies using cloned autoantigen CENP-B. Arth Rheum 1987; 30: 1416–1420
- Laemmli UD. Cleavage of structural protein during the assembly of the head of bacteriophage T4. Nature 1970; 227: 681
- Bona CA. Regulatory Idiotypes. John Wiley & Sons, New York 1987; 232
- Zanetti M, Katz DH. Self-recognition, autoimmunity and internal images. C.T. Microbiology 1985; 119: 113–128
- Harkiss G D, Hendrie F M, Thompson D. Anti-Klebsiella K30 phospholipid antibodies in systemic lupus eythematosus: antigen cross-reaction and idiotypic sharing with antibodies to DNA and Klebsiella K30 polysaccharide. J Clin Imm 1988; 8: 319–331
- Datta S K, Naparsteck Y, Schwartz RS. In vitro production of an anti-DNA antibody idiotype by lymphocytes of normal subjects and patients with systemic lupus erythematosus. Clin Immunol Immunopathol 1986; 38: 302–308
- Williams W, Zumla A, Behrens R, Locniskar M, Voller A, McAdam K PWJ, Isenberg DA. Studies of a common idiotype PR4 in autoimmune rheumatic disease. Arth Rheum 1988; 31: 1097–1104
- Ilowite N T, Wedgwood J F, Bonagura V. Expression of the major rheumatoid factor cross-reactive idiotype in juvenile rheumatoid arthritis. Arth Rheum 1989; 32: 265–270
- Rossi F, Dietrich G, Kazatchkine M. Anti-Idiotypes against autoantibodies of human autoimmune responses. Immunol Rev 1989; 110: 135–149
- Earnshaw W C, Machlin P, Bordwell B J, Rothfield NF. Analysis of anticentromere autoantibodies using cloned autoantigen CENP-B. Proc Natl Acad Sci USA 1987; 84: 1–5
- Shlomchik M J, Marshak-Rothstein A, Wolfowicz C B, Rothstein T HL, Weigert MG. The role of clonal selection and somatic mutation in autoimmity. Nature 1987; 328: 805–811
- Shlomchick M J, Mascelli M, Shan H, Radic MZ. Pisetsky D, Marshak-Rothstein A, Weigert MG. Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation. J Exp Med 1990; 171: 265–297
- Miller A. The effect of immune memory on repertoire expression. Immunogenicity of protein antigens: repertoire and regulation, EE Sercarz, JA Berzofsky. CRC Press Inc, Florida 1987; Volume I: 105–109
- French D L, Laskov R, Scharff MD. The role of somatic hypermutation in the generation of antibody diversity. Science 1988; 244: 1152–1158
- Kocks C, Rajewsky K. Stable expression and somatic hypermutation of antibody V rgions in B cell development pathyways. Annul Rev of Immunol 1989; 7: 537–559
- Casali P, Notkins AL. Probing the human B-cell repetoire with EBV: Polyreactive antibodies and CD5 + B lymphocytes. Ann Rev of Immunol 1989; 7: 513–535
- Tron F, Bach JF. Molecular and genetic characteristics of pathogenic autoantibodies. J Autoimmunity 1989; 2: 311–320