Autoimmune Gastritis: Tolerance and Autoimmunity to the Gastric H⁺/K⁺ Atpase (Proton Pump)

References

• Strickland R. Gastritis. Springer Semin Immunopathol 1990; 12: 203–217
   PubMed Web of Science ®Google Scholar
• Strickland R, Mackay I R. A reappraisal of the nature and significance of chronic atrophic gastritis. Am J Dig Dis 1973; 18: 426–440
   PubMedGoogle Scholar
• Gleeson P A, Toh B H. Molecular targets in pernicious anaemia. Immunol Today 1991; 12: 233–238
   PubMedGoogle Scholar
• Irvine W J, Cullen D R, Mawhinney H. Natural history of autoimmune achlorhydric atrophic gastritis. Lancet 1974; ii: 482–485
   Google Scholar
• Kekki M, Siurala M, Varis K. Classification principles and genetics of chronic gastritis. Scand J Gastroenterol 1987; 22: 1–28, (Suppl 141)
   PubMed Web of Science ®Google Scholar
• Whittingham S, Mackay I R, Tail B D. The Immunogenetics of Autoimmune Diseases, N R Farid. CRC Press. 1991; Vol 2: 215–227
   Google Scholar
• Pedersen P L, Carafoli E. Ion motive ATPases. 1. Ubiquity, properties and significance to cell function. Trends in Biochem Sci 1987; 12: 146–150
   Web of Science ®Google Scholar
• Okamoto C T, Karipilow J M, Smolka A, Forte J G. Isolation and characterization of gastric microsomal glycoproteins. Evidence for a glycosylated β-subunit of the H+/K+-ATPase. Biochem Biophys Acta 1990; 1037: 360–372
   PubMed Web of Science ®Google Scholar
• Shull G. cDNA cloning of the β-subunit of the rat gastric H,K-ATPase. J Biol Chem 1990; 265: 12123–12126
   PubMed Web of Science ®Google Scholar
• Toh B H, Gleeson P A, Simpson R J, Mortiz R L, Callaghan J, Goldkorn I, Claerwen M Jones, Martinelli T M, Mu F T, Humphris D C, Pettitt J M, Mori Y, Masud T, Sobieszczuk P, Weinstock J, Mantamadiotis T, Baldwin G S. The 60–90 kDa parietal cell autoantigen associated with autoimmune gastritis is a β subunit of the gastric H+/K+-ATPase (proton pump). Proc Natl Acad Sci USA 1990; 87: 6418–6422
   PubMed Web of Science ®Google Scholar
• Reuben M A, Lasater L S, Sachs G. Characterization of a β subunit of the gastric H+/K+-transporting ATPase. Proc Natl Acad Sci USA 1990; 87: 6767–6771
   PubMed Web of Science ®Google Scholar
• Morley G P, Callaghan J M, Rose J B, Toh B H, Gleeson P A, van Driel Ian R. The mouse gastric H-K ATPase β subunit: gene structure and co-ordinate expression with the α subunit during ontogeny. J Biol Chem 1992; 267: 1165–1174
   PubMed Web of Science ®Google Scholar
• Horowitz B, Eakle K A, Scheiner-Bobis G, Randolph G R, Chen C Y, Hitzeman R A, Farley R A. Synthesis and assembly of functional mammalian Na, K-ATPase in yeast. J Biol Chem 1990; 265: 4189–4192
   PubMed Web of Science ®Google Scholar
• Noguchi S, Maeda M, Futai M, Kawamura M. Assembly of a hybrid from the α subunit of Na+/K+-ATPase and the β subunit of H+/K+-ATPase. Biochem Biophys Res Commun 1992; 182: 659–666
   PubMed Web of Science ®Google Scholar
• Hoedemaeker P J, Ito S. Ultrastructual localisation of gastric parietal cell antigen with peroxidase-coupled antibody. Lab Invest 1970; 22: 184–188
   PubMed Web of Science ®Google Scholar
• Ward H A, Nairn R C. Gastric parietal cell autoantigen. Physical, chemical and biologic properties. Clin Exp Immunol 1972; 10: 435–457
   PubMed Web of Science ®Google Scholar
• Shull G E, Lingrel J B. Molecular cloning of the rat stomach (H++K+)-ATPase. J Biol Chem 1986; 261: 16788–16791
   PubMed Web of Science ®Google Scholar
• Callaghan J, Toh B H, Pettitt J M, Humphris D C, Gleeson P A. Poly-N-acetylactosamine-specific tomato lectin interacts with gastric parietal cells. Identification of a tomato-lectin binding 60–90×103 M, membrane glycoprotein of tubulovesicles. J Cell Sci 1990; 95: 563–576
   PubMed Web of Science ®Google Scholar
• Callaghan J, Toh B H, Simpson R J, Baldwin G S, Gleeson P A. Rapid purification of the gastric H+/K+ ATPase complex by tomato lectin affinity chromatography. Biochem J 1992; 283: 63–68
   PubMed Web of Science ®Google Scholar
• Dow C A, de Aizpurua H J, Pedersen J S, Ungar B, Toh B H. 65–70 kD protein identified as the presumptive gastric microsomal autoantigen in pernicious anaemia. Clin Exp Immunol 1985; 62: 732–737
   PubMed Web of Science ®Google Scholar
• Karlsson F A, Burman P, Loof L, Mardh S. Major pariental cell antigen in autoimmune gastritis with pernicious anaemia is the acid-producing H+, K+ adenosine trisphosphatase of the stomach. J Clin Invest 1988; 81: 475–479
   PubMed Web of Science ®Google Scholar
• Goldkorn I, Gleeson P A, Toh B H. Gastric parietal cell antigens of 60–90 kDa, 92 kDa and 100–120 kDa associated with autoimmune gastritis and pernicious anaemia. Role of N-glycans is the structure and antigenicity of the 60–90 kDa component. J Biol Chem 1989; 264: 18768–18774
   PubMed Web of Science ®Google Scholar
• Jones C M, Toh B H, Pettitt J M, Martinelli T M, Humphris D, Callaghan J M, Goldkorn I, Mu F-T, Gleeson P A. Monoclonal antibodies specific for the core protein of the β-subunit of the gastric proton pump. Eur J Biochem 1991; 197: 49–59
   PubMedGoogle Scholar
• Hennessey J P, Scarborough G A. An optimized procedure for sodium dodecyl sulphate-polyacrylamide gel electrophoresis analysis of hydrophobic peptides from an integral membrane protein. Anal Biochem 1989; 176: 284–289
   PubMed Web of Science ®Google Scholar
• Goldkorn I, Gleeson P A, Toh B H. Reverse immunoaffinity chromatography: Application to the purification of the 60–90 kDa gastric parietal cell autoantigen associated with autoimmune gastritis. Anal Biochem 1991; 194: 433–438
   PubMed Web of Science ®Google Scholar
• Kojima A, Prehn R T. Genetic susceptibility of post-thymectomy autoimmune diseases in mice. Immunogenetics 1981; 14: 15–27
   PubMed Web of Science ®Google Scholar
• Fukuma K, Sakaguchi S, Kuribayashi K, Chen W L, Morishita R, Seikita K, Uchino H, Masuda T. Immunologic and clinical studies on murine experimental autoimmune gastritis induced by neonatal thymectomy. Gastroenterology 1988; 94: 274–283
   PubMed Web of Science ®Google Scholar
• Tung K SK, Smith S, Teuscher C, Cook C, Anderson R E. Murine autoimmune oophoritis, epididymoorchitis and gastritis induced by day 3 thymectomy. Am J Pathol 1987; 126: 293–302
   PubMed Web of Science ®Google Scholar
• Taguchi O, Nishizuka Y. Autoimmune oophoritis in thymectomized mice: T cell requirement for adoptive cell transfer. Clin exp Immunol 1980; 42: 324–331
   PubMed Web of Science ®Google Scholar
• Mori Y, Fukuma K, Adachi Y, Shigeta K, Kannagi R, Tanaka H, Sakai M, Kuribayashi K, Uchino H, Masuda T. Characterization of parietal cell autoantigens involved in neonatal thymectomy-induced murine autoimmune gastritis using monoclonal autoantibodies. Gastroenterol 1989; 97: 364–375
   PubMed Web of Science ®Google Scholar
• Jones C M, Callaghan J M, Gleeson P A, Mori Y, Masuda T, Toh B H. The parietal cell autoantigens recognised by neonatal thymectomy-induced murine gastritis are the α and β subunits of the gastric proton pump. Gastroenterology 1991; 101: 287–294
   PubMed Web of Science ®Google Scholar
• Sakaguchi S. Sakaguchi Organ N.-specific autoimmune disease induced by elimination of T cell subsets. V. Neonatal administration of cyclosporin A causes autoimmune disease. J Immunol 1989; 142: 471–480
   PubMed Web of Science ®Google Scholar
• Sakaguchi S, Fukuma K, Kuribayashi K, Masuda T. Organspecific autoimmune diseases induced in mice by elimination of T cell subset. J Exp Med 1985; 161: 72–87
   PubMed Web of Science ®Google Scholar
• Smith H., Lou Y H, Lacy P, Tung S K, Personal communication
   Google Scholar
• Sakaguchi S, Takahashi T, Nishizuka Y. Study on cellular events in post-thymectomy autoimmune oophrotis in mice. J Exp Med 1982; 156: 1565–1576
   PubMed Web of Science ®Google Scholar
• Sakaguchi S, Sakaguchi N. Thymus and autoimmunity: capacity of the normal thymus to produce pathogenic self-reactive T cells and conditions required for their induction of autoimmune disease. J Exp Med 1990; 172: 537–545
   PubMed Web of Science ®Google Scholar
• Mori Y, Hosono M, Murakami K, Katoh H, Yoshikawa Y, Kuribayashi K, Kannagi R, Sakai M, Okuma M, Masuda T. Genetic studies on experimental autoimmune gastritis induced by neonatal thymectomy using recombinant inbred strains between a high incidence strain, BALB/c and a low incidence strain, DBA/2. Clin Exp Immunol 1991; 84: 145–152
   PubMed Web of Science ®Google Scholar
• Taguchi O, Nishizuka Y. Self tolerance and localised autoimmunity. Mouse models of autoimmune disease that suggest tissue-specific suppressor T cells are involved in self tolerance. J Exp Med 1987; 165: 146–156
   PubMed Web of Science ®Google Scholar
• Smith H, Sakamoto Y, Kasai K, Tung K SK. Effector and regulatory cells in autoimmune oophoritis elicited by neonatal thymectomy. J Immunol 1991; 147: 2928–2933
   PubMed Web of Science ®Google Scholar
• Powrie F, Mason D. OX-22high CD4+ T cells induce wasting disease with multiple organ pathology: prevention by the OX-22low subset. J Exp Med 1990; 172: 1701–1708
   PubMed Web of Science ®Google Scholar
• Powrie F, Mason D. Correction. J Exp Med 1991; 173: 1037
   Google Scholar
• Penhale W J, Ahmed S A. Lymphocyte thyroiditis. Autoimmune thyroiditis in rats induced by thymectomy and irradiation. Am J Path 1982; 106: 300–302
   PubMed Web of Science ®Google Scholar
• Ahmed S A, Penhale W J. Pathological changes in inbred strains of mice following early thymectomy and irradiation. Experientia 1981; 37: 1341–1343
   PubMedGoogle Scholar
• Wick G, Brezinschek H P, Hala K, Dietrich H, Wolf H, Kroemer G. The obese strain of chickens: an animal model with spontaneous autoimmune thyroiditis. Adv Immunol 1989; 47: 433–500
   PubMed Web of Science ®Google Scholar
• Ahmed S A, Penhale W J. Thyroid transplantation in rats developing autoimmune thyroiditis following thymectomy and irradiation. Clin Exp Immunol 1981; 45: 480–486
   PubMed Web of Science ®Google Scholar
• Mosmann T R, Schumacher J H, Street N F, Budd R, O'Garra A, Fong T AT, Bond M W, Moore K WM, Sher A, Fiorentino D F. Diversity of cytokine synthesis and function of mouse CD4+ T cells. Immunol Rev 1991; 123: 209–229
   PubMed Web of Science ®Google Scholar
• Mosmann T R, Coffman R L. TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties. Ann Rev Immunol 1989; 7: 145–173
   PubMed Web of Science ®Google Scholar
• Karpus W J, Swanborg R L. CD4+ suppressor cells inhibit the function of effector cells of experimental autoimmune encelphalomyelitis through a mechanism involving transforming growth factor-β. J Immunol 1991; 146: 1163–1168
   PubMed Web of Science ®Google Scholar
• Adams T E, Alpert S, Hanahan D. Non-tolerance and autoantibodies to a transgenic self antigen expressed in pancreatic β cells. Nature 1987; 325: 223–228
   PubMed Web of Science ®Google Scholar
• Miller R P, Farley R A. β subunit of the (Na++K+)-ATPase contains three disulphide bonds. Biochemistry 1990; 29: 1524–1532
   PubMed Web of Science ®Google Scholar