The Third Euromyasthenia Conference; Meeting Report and Update on Myasthenia Research

References

• Walker M B. Treatment of myasthenia gravis with physostig‐mine. Lancer 1934; i: 1200–1201
   Google Scholar
• Chang C E, Lee C Y. Isolation of neurotoxins from the venom of Bungarus multicinctus and their modes of neuromuscular blocking action. Arch Pharmacodyn Ther 1962; 144: 241–257
   Google Scholar
• Patrick J, Lindstrom J. Autoimmune response to acetylcholine receptor. Science 1973; 180: 871–872
   PubMed Web of Science ®Google Scholar
• Simpson J A. Myasthenia gravis: a new hypothesis. Scott Med J 1960; 5: 419–439
   Google Scholar
• Lindstrom J M, Seybold M E, Lennon V A, Whittingham S, Duane D D. Antibody to acetylcholine receptor in myasthenia gravis. Prevalence, clinical correlates and diagnostic value. Neurology 1976; 26: 1054–1059
   PubMed Web of Science ®Google Scholar
• Takai T, Noda M, Mishina M, Shimizu S, Furutani Y, Kayano T, Ikeda T, Kubo T, Takahashi H, Takahashi T, Kuno M, Numa S. Cloning, sequencing and expression of cDNA for a novel subunit of acetylcholine receptor from calf muscle. Nature 1985; 315: 761–764
   PubMed Web of Science ®Google Scholar
• Willcox N, Vincent A. Myasthenia gravis as an example of organ‐specific autoimmune disease. B Lymphocytes in Human Disease, G Bird, J E Calvert. Oxford University Press. 1988; 469–506
   Google Scholar
• Claudio T. Molecular genetics of acetylcholine receptor‐channels. Frontiers in Molecular Biology: Molecular Neurobiology Volume, D M Glober, B D Hames. IRL Press, Oxford 1989; 63–142
   Google Scholar
• Sttihmer W, Conti F, Suzuki H, Wang X, Noda M, Yahagi N, Kubo H, Numa S. Structural parts involved in activation and inactivation of the sodium channel. Nature 1989; 339: 597–603
   PubMed Web of Science ®Google Scholar
• Vincent A, Lang B, Newsom‐Davis J. Autoimmunity to the voltage‐gated calcium channel underlies the Lambert‐Eaton myasthenic syndrome, a paraneoplastic disorder. Trends Neurosci 1989; 12: 491–502
   Web of Science ®Google Scholar
• Sinha S, Newsom‐Davis J, Mills K, Byrne N, Lang B, Vincent A. Autoimmune aetiology for acquired neuromyotonia (Isaacs' syndrome). Lancet 1991; ii: 75–77
   Google Scholar
• Tzartos S J, Barkas T, Cung M T, Kordossi A, Loutrari H, Mar‐raud M, Papadouli I, Sakarellos C, Sophianos D, Tsikaris V. The main immunogenic region of the acetylcholine receptor: structure and role in myasthenia gravis. Autoimmunity 1991; 8: 259–270
   PubMed Web of Science ®Google Scholar
• Saedi M S, Anand R, Conroy W G, Lindstrom J. Determination of amino acids critical to the main immunogenic region of intact acetylcholine receptors by in vitro mutagenesis. FEBS Lett 1990; 267: 55–59
   PubMed Web of Science ®Google Scholar
• Melms A, Chrestel S, Schalke B CG, Wekerle H, Mauron A, Ballivet M, Barkas Y. Autoimmune T lymphocytes in myasthenia gravis: determination of target epitopes using T cell lines and recombinant products of the mouse nicotinic acetylcholine receptor gene. J Clin Invest 1989; 83: 785–790
   PubMed Web of Science ®Google Scholar
• Hohlfeld R, Toyka K V, Heininger K, Gross‐Wilde H, Kalies I. Autoimmune human T lymphocytes specific for acetylcholine receptor. Nature 1984; 310: 244–246
   PubMed Web of Science ®Google Scholar
• Ong B, Willcox N, Wordsworth P, Beeson D, Vincent A, Altmann D, Lanchbury J SS, Harcourt G C, Bell J I, Newsom‐Davis J. Critical role for the Val/Gly86 HLA.‐DR β dimorphism in autoantigcn presentation to human T cells. Proc Natl Acad Sri USA 1991; 88: 7343–7347
   PubMed Web of Science ®Google Scholar
• Willcox H NA, Schluep M, Ritter M A, Schuurman H J, Newsom‐Davis J, Christensson B. Myasthenic and nonmyas‐thenic thymoma: an expansion of a minor cortical epithelial cell subset?. Am J Pathol 1987; 127: 447–460
   PubMed Web of Science ®Google Scholar
• Aarli J A, Lefvert A ‐K, Tonder O. Thymoma‐specific antibodies in sera from patients with myasthenia gravis demonstrated by indirect haemagglutination. J Neuroimmunol 1981; 1: 421–427
   PubMed Web of Science ®Google Scholar
• Gilhus N ‐E, Aarli J A, Christensson B, Matre R. Rabbit antiserum to a citric acid extract of human skeletal muscle staining thymomas from myasthenia gravis patients. J Neuroimmunol 1984; 7: 55–64
   PubMed Web of Science ®Google Scholar
• Kirchner T, Tzartos S, Hoppe F, Schalke B, Wekerle H, Milll‐er‐Hermelink H K. Pathogenesis of myasthenia gravis: acetylcholine receptor‐related antigenic determinants in tumor‐free thymuses and thymic epithelial tumors. Am J Pathol 1988; 130: 268–280
   PubMed Web of Science ®Google Scholar
• Marx A, O'Connor R, Geuder K I, Hoppe F, Schalke B, Tzartos S, Kalies I, Kirchner T, Muller‐Hermelink H K. Characterization of a protein with an acetylcholine receptor epitope from myasthenia gravis‐associated thymomas. Lab Invest 1990; 62: 279–286
   PubMed Web of Science ®Google Scholar
• Williams C L, Lennon V A. Thymic β lymphocyte clones from patients with myasthenia gravis secrete monoclonal striational antibodies reacting with myosin, alpha‐actinin or actin. J Exp Med 1986; 164: 1043–1059
   PubMed Web of Science ®Google Scholar
• Kao I, Drachman D B. Thymic muscle cells bear acetylcholine receptors: possible relation to myasthenia gravis. Science 1977; 195: 74–75
   PubMed Web of Science ®Google Scholar
• Wekerle H, Ketelsen U ‐P. Intrathymic pathogenesis and dual genetic control of myasthenia gravis. Lancet 1977; i: 678–680
   Google Scholar
• Schluep M, Willcox N, Ritter M A, Newsom‐Davis J, Larche M, Brown A N. Myasthenia gravis thymus: clinical, histological and culture correlations. J Autoimmun 1988; 1: 445–467
   PubMed Web of Science ®Google Scholar
• Schluep M, Willcox N, Vincent A, Dhoot G K, Newsom‐Davis J. Acetylcholine receptors in human thymic myoid cells in situ: an immunohislological study. Ann Neurol 1987; 22: 212–222
   PubMed Web of Science ®Google Scholar
• Kirchner T, Hoppe F, Schalke B, Muller‐Hermelink H K. Microenvironment of thymic myoid cells in myasthenia gravis. Virch Archiv B Cell Pathol 1988; 54: 295–302
   Google Scholar