Human Cd8+ T Cell Clone Regulates Autologous Cd4+ Myelin Basic Protein Specific T Cells

References

• Burns J, Rosenzweig A, Zweiman B, Lisak R P. Isolation of myelin basic protein-reactive T-cell lines from normal human blood. Cell Immunol 1983; 81: 435–440
   PubMed Web of Science ®Google Scholar
• Vandenbark A A, Chou Y K, Bourdette D, Whitham R, Chilgren J, Chou C H-J, Konat G, Hashim G, Vainiene M, Offner H. Human T lymphocyte response to myelin basic protein: Selection of T lymphocyte lines from MBP responsive donors. J Neurosci Res 1989; 23: 21–30
   Google Scholar
• Martin R, Jaraquemada D, Flerlage M, Richert J, Whitaker J, Long E O, McFarlin D E, McFarland H F. Fine specificity and HLA restriction of myelin basic protein-specific cytotoxic T cell lines from multiple sclerosis patients and healthy individuals. J Immunol 1990; 145: 540–548
   PubMed Web of Science ®Google Scholar
• Mitchison N A. Logical structure of the immunoregulatory compartment. Hamatol Bluttransfus 1989; 32: 257
   Google Scholar
• Strober W, James S P. Immunoregulatory functions of human autoreactive T-cell lines and clones. Immunol Rev 1990; 116: 117–138
   PubMedGoogle Scholar
• Finnegan A, Needleman B W, Hodes R J. Function of autoreactive T cells in immune responses. Immunol Rev 1990; 116: 15–31
   PubMed Web of Science ®Google Scholar
• Lamb J R, Feldmann M. A human suppressor T cell clone which recognize an autologous helper T cell clones. Noture 1982; 300: 456–458
   Google Scholar
• Sun D, Qin Y, Chluba J, Epplen J T, Wekerle H. Suppression of experimentally induced autoimmune encaphalomyelitis by cytolytic T-Tcell interactions. Nature 1988; 332: 843–845
   PubMed Web of Science ®Google Scholar
• Whitacre C C, Bitar D M. Suppression of experimental allergic encephalomyelitis (EAE) by the oral administration of myelin basic protein (MBP). Abstracts of the 6th International Congress of Immunology, TorontoCanada, 1986, 468
   Google Scholar
• Higgins P J, Weiner H L. Suppressor of experimental autoimmune encephalomyelitis by oral administration of myelin basic protein and its fragments. J Immunol 1988; 140: 440–445
   PubMed Web of Science ®Google Scholar
• Wucherpfennig K W, Weiner H L, Hafler D A. T-cell recognition of myelin basic protein. Immunol Todoy 1991; 12: 277–282
   PubMedGoogle Scholar
• Allegretta M, Nicklas J A, Sriram S, Albertini R J. T cell responsive to myelin basic protein in patients with multiple sclerosis. Science 1990; 247: 718–721
   PubMed Web of Science ®Google Scholar
• Olsson T, Wang W Z, Hojeber B, Kostulas V, Jiang Y P, Anderson G, Ekre H-P, Link H. Autoreactive T lymphocytes in multiple sclerosis determined by antigen-induced secretion of IFN-γ. J Clin Invest 1990; 86: 981–985
   PubMed Web of Science ®Google Scholar
• Antel J P, Peeples D M, Reder A T, Arnason G W. Analysis of T regulator cell surface markers and functional properties in multiple sclerosis. J Neuroimmunol 1984; 6: 93–103
   PubMedGoogle Scholar
• Trotter J L, Clifford D B, McInnis J E, Griffeth R C, Bruns K A, Perlmutter M S, Anderson C B, Collins K G, Banks G, Hicks B C. Correlation of immunological studies and disease progression in chronic progessive multiple sclerosis. Ann Neurol 1989; 25: 172–178
   PubMed Web of Science ®Google Scholar
• Antel J P, Arnason G W, Medof M E. Suppressor cell function in multiple sclerosis: correlation with clinical disease activity. Ann Neurol 1978; 5: 338–342
   Google Scholar
• Reder A T, Antel J P, Oger J-F, McFarland T A, Rosenkoetter M, Arnason B GW. Low T8 antigen density on lymphocytes in active multiple sclerosis. Ann Neurol 1984; 16: 242–249
   PubMedGoogle Scholar
• Antel J P, Bania M B, Reder A, Cashman N. Activated suppressor cell dysfunction in progressive multiple sclerosis. J Immunol 1986; 137: 137–141
   PubMed Web of Science ®Google Scholar
• Chofflon M, Weiner H L, Morimoto C, Hafler D A. Loss of functional suppression is linked to decreases in circulating suppressor inducer (CD4+ 2H4+) T cells in multiple sclerosis. Ann Neurol 1988; 24: 185–191
   PubMed Web of Science ®Google Scholar
• Chou Y K, Vainiene M, Whitham R, Bourdette D, Chou C H-J, Hashim G, Offner H, Vandenbark A A. Response of human T lymphocyte lines to myelin basic protein: Association of dominant epitopes with HLA class II restriction molecules. J Neurosci Res 1989; 23: 207–216
   PubMed Web of Science ®Google Scholar
• Chou Y K, Henderikx P, Vainiene M, Whitham R, Bourdette D, Chou C H-J, Hashim G, Offner H, Vandenbark A A. Specificity of human T cell clones reactive to immunodominant epitopes of myelin basic protein. J Neurosci Res 1991; 28: 280–290
   PubMed Web of Science ®Google Scholar
• Ota K, Matsui M, Milford E L, Mackin G A, Weiner H L, Hafler D A. T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 1990; 346: 183–187
   PubMed Web of Science ®Google Scholar
• Kotzin B, Karuturi S, Chou Y K, Lafferty J, Forrester J M, Better M, Nedwin G E, Offner H, Vandenbark A A. Preferential T cell receptor Vβ gene usage in myelin basic protein reactive T cell clones from patients with multiple sclerosis. Proc Nail Acad Sci USA 1991; 88: 9161–9165
   PubMed Web of Science ®Google Scholar
• Eylar E H, Brostoff S W, Hashim G, Caccam J, Burnett P. Basic Al protein of the myelin membrane: The complete amino acid sequence. J Biol Chem 1971; 246: 5770–5784
   PubMed Web of Science ®Google Scholar
• Chou F C-H, Chou C H-J, Kowalski T I, Shapira R, Kibler R F. The major role site of guinea-pig myelin basic protein ence-phalitogenic in Lewis rats. J Neurochem 1977; 28: 115–119
   PubMed Web of Science ®Google Scholar
• Hashim G A, Day E D, Fredane L, Intintola P, Carvalho E. Biological activity of region 65 to 102 of the myelin basic protein. J Neurosci Res 1986; 16: 467–478
   Google Scholar
• Kawai K, Zweiman B. Cytotoxic effect of myelin basic proteinreactive T cells on cultured oligodendrocytes. J Neuroimmunol 1988; 19: 159–165
   Google Scholar
• Ruijs T CG, Freedman M S, Grenier Y G, Olivier A, Antel J P. Human oligodendrocytes are suceptible to cytolysis by major histocompatibility complex class I-restricted lymphocytes. J Neuroimmunol 1990; 27: 89–97
   Google Scholar
• Choi Y, Kotzin B, Herron L, Callahan J, Marrack P, Kappler J. Interaction of staphylococcus aureus toxin “superantigen” with human T cells. Proc Nail Acad Sci USA 1989; 86: 8941–8945
   PubMed Web of Science ®Google Scholar
• Morrison W J, Offner H, Vandenbark A A. Transmembrane signalling associated with ganglioside-induced CD4 modulation. Immunopharmacol 1990; 20: 135–141
   Google Scholar
• Vandenbark A A, Hashim G, Offner H. Immunization with a synthetic T-cell receptor V-region peptide protects against experimental autoimmune encephalomyelitis. Nature 1989; 341: 541–544
   PubMed Web of Science ®Google Scholar
• Sakane T, Sternberg A D, Green I. Failure of the autologous mixed lymphocyte reaction between T and non-T cells in patients with systemic lupus erythematosis. Proc Nail Acad Sci USA 1978; 75: 3464–3468
   PubMedGoogle Scholar
• Hafler D A, Buchsbaum M, Weiner H L. Decreased autologous mixed lymphocyte reaction in multiple sclerosis. J Neuroimmunol 1985; 9: 339–347
   PubMed Web of Science ®Google Scholar
• Nieda M, Juji T, Imao S, Minami M. A role of HLA-DQ molecules of stimulator-adherent cells in the regulation of human autologous mixed lymphocyte reaction. J Immunol 1988; 141: 2975–2979
   Google Scholar
• Meuer S C, Hussey R E, Hodgdon J C, Hercend T, Schlossman S F, Reinherz E L. Surface structures involved in target recognition by human cytotoxic T lymphocytes. Science 1982; 218: 471–473
   PubMed Web of Science ®Google Scholar
• Koh D-R, Fung-Leung W-P, Ho A, Gray H, Acha-Orbea H, Mak T W. Less mortality but more relapses in experimental allergic encephalomyelitis in CD8–/- mice. Science 1992; 256: 1210–1213
   PubMed Web of Science ®Google Scholar
• Jiang H, Zhang S-L, Pernis B. Role of CD8+ T cells in murine experimental allergic encephalomyelitis. Science 1992; 256: 1213–1215
   PubMed Web of Science ®Google Scholar