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Original Article

Multiple Sclerosis Susceptibility. Population and Twin Study of Polymorphisms in the T-Cell Receptor β and γ Genes Region

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Pages 67-73 | Received 20 Jan 1993, Published online: 07 Jul 2009

References

  • MacFarland H F, Dhib-Jalbut S. Multiple sclerosis: possible immunological mechanisms. Clin Immunopathol 1989; 50: 96–99
  • Spielman R S, Nathanson N. The genetics of susceptibility to multiple sclerosis. Epidemiol Rev 1982; 4: 45–65
  • MacFarland H F, Greenstein J, MacFarlin D E, Elbridge R, Xu X H, Krebs H. Family and twin studies in multiple sclerosis. Ann NY Acad Sci 1984; 436: 118–124
  • Ebers G C, Bulman D E, Sadovnik A D, Paty D W, Warren S, Hader W, Murray T J, Seland T P, Duquette P, Grey T, Nelson R, Nicolle M, Brunet DA. Population-based study of multiple sclerosis in twins. New Engl J Med 1986; 315: 1638–1642
  • Bertrams J, Kuwert E. HLA antigens frequencies in multiple sclerosis. Eur J Neurol 1972; 7: 74–79
  • Bertrams J, Kuwert E. Association of histocompatibility haplotypes HLA-A3, B7 with multiple sclerosis. J Immunol 1976; 117: 1906–1911
  • Opelz G, Terasaki P, Myers L, Ebers G, Ellison G, Zahiskie J, Kempe H, Sibley W, Werner H. The association of HLA antigens A3, B7 and Dw2 with 330 multiple sclerosis patients in United States. Tissue Antigens 1977; 9: 54–60
  • Cohen D, Cohen O, Marcadet A, Lathrop M, Deschamps I, Hors J, Schuller E, Dausset J. Class II DC beta chain DNA restriction fragments differentiate among HLA-DR2 individuals in insulin-dependent diabetes and multiple sclerosis. Proc Natl Acad Sci USA 1984; 81: 1774–1778
  • Spurkland A, Ronningen K S, Vandik B, Thorsby E, Vartdal F. HLA-DQA1 and HLA-DQB1 genes may jointly determine susceptibility to develop a multiple sclerosis. Hum. Immunol 1991; 30: 69–74
  • Odum N, Hyldig-Nielsen J J, Morling N, Sandberg-Wollheim M. Platz P. and Svejgaard A. HLA-DP antigens are involved in the susceptibility to multiple sclerosis. Tissue Antigens 1988; 31: 235–237
  • Roth M P, Coppin H, Descoins P, Ruidavets J B, Cambon-Thomsen A, Clanet M. HLA-DPB1 gene polymorphism and multiple sclerosis: a large case-control study in the south west of France. J Neuroimmunol 1991; 34: 215–222
  • Waksman PH. Autoimmunity in demyelinating diseases. Ann NY Acad Sci 1988; 540: 13–24
  • Acha-Orbea H, Mitchell D J, Timmerman L, Wraith D C, Tausch G S, Waldor M K, Zamvil S S, MacDevitt H O, Steinman L. Limited heterogeneity of T-cell receptor from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention. Cell 1988; 54: 263–273
  • Davis M M, Bjorkman PJ. T-cell antigen receptor genes and T-cell recognition. Nature 1988; 334: 395–402
  • Triebel F, Faure F, Grazini M, Jitsukawa S, Lefranc M P, Hercend TA. Unique V J C rearranged gene encodes a gamma protein expressed on the majority of CD3+ T-cell receptor alpha, beta-circulating lymphocytes. J Exp Med 1988; 167: 694–699
  • Beall S S, Concannon P, Charmley P, MacFarland H F, Gatty R A, Hood L E, MacFarlin D E, Biddison J. The germline repertoire of T-cell receptor β chain genes in patients with chronic progressive multiple sclerosis. J Neuroimmunol 1989; 21: 59–66
  • Seboun E, Robinson M A, Doolittle T H, Ciulla T A, Kindt T J, Hauser SL. A susceptibility locus for multiple sclerosis is linked to the T-cell receptor β gene complex. Cell 1989; 57: 1095–1100
  • Hillert J, Olerup O. Germ-line polymorphism of TCR genes and disease susceptibility—Fact or hypothesis. Immunol Today 1992; 13: 47–49
  • Brenner M B, McLean J, Dialynas D P, Strominger J L, Smith J A, Owen F L, Seidman J G, Ip S, Rosen F, Krangel MS. Identification of a putative second T-cell receptor. Nature 1986; 322: 145–149
  • Faure F, Jitsukawa S, Triebel F, Hercend T. CD3/Ti gamma: a functional gamma receptor complex expressed on human peripheral lymphocytes. J Immunol 1988; 140: 1372–1375
  • Kjeldsen-Kragh J, Quayle A, Kalvenes C, Fome O, Sorkaar D, Vinje O, Thoen J, Natvig JB. T gamma/delta cells in juvenile rheumatoid arthritis. J Immunol 1990; 32: 651–653
  • Faucher R, Semana G, Middleton D, Savage D, Brahmi Z, Wegener S, Le Petit J C, Acquart S, Vartdal F. Multiple sclerosis report. HLA 1991, Tsuji. Oxford University Press. 1992; Vol. 1: 734–740
  • Selmaj K, Brosnan C F, Raine C. Colocalization of lymphocytes bearing gamma/delta T-cell receptor and heat shock protein Hsp65+ oligodendrocyte in multiple sclerosis. Proc Natl Acad Sci USA 1991; 88: 6452–6456
  • French Research Group on Multiple Sclerosis 1992. Multiple sclerosis in 54 twinships: concordance rate is independent of zygosity. Ann Neurol 1992; 32: 724–727
  • Poser C, Paty D W, Schainberg L, McDonald Q, Floyd A, Ebers G, Sibley W, Silberberg D, Johnson K, Toutelotte W. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983; 13: 227–232
  • Concannon P, Pickering L A, Kung P, Hood LE. Diversity and structure of human receptor β chain variable region genes. Proc Natl Acad Sci USA 1986; 83: 6598–6602
  • Concannon P, Gatti R A, Hood LE. Human T-cell receptor Vβ gene polymorphism. J Exp Med 1987; 165: 1130–1140
  • Wong Z, Wilson V, Jeffreys A J, Thein SL. Cloning a selected fragment of a human fingerprint: isolation of an extremely polymorphic minisatellite. Nucl Acid Res 1986; 14: 4605–4616
  • Lefranc M P, Forster A, Baer R, Stinson M A, Rabbits TH. Diversity and rearrangement of human T-cell rearranging genes: germline variable genes belonging to two subgroups. Cell 1986; 45: 237–246
  • Font M P, Chen Z, Bories J C, Duparc N, Loiseau P, Degos L, Cann H, Cohen D, Dausset J, Sigaux F. The V gamma locus of the human T-cell receptor genes. J Exp Med 1988; 168: 1383–1401
  • Oksenberg J R, Sherritt M, Begovitch A B, Erlich H A, Bernard C, Cavalli-Sforza L L, Steinman L. T-cell receptor V alpha and C alpha alleles associated with multiple sclerosis and myasthenia gravis. Proc Natl Acad Sci USA 1989; 86: 988–992
  • Charmley P, Concannon P, Gatty RA. T-cell receptor β chain DNA polymorphism frequencies in healthy HLA-DR homozygotes. Tissue Antigens 1990; 35: 157–164
  • Fugger L, Sandberg-Wollheim M, Morling N, Ryder L P, Svejgaard A. The germline repertoire of T-cell receptor β chain genes in patients with relapsing/remitting multiple sclerosis or optic neuritis. Immunogenetics 1990; 31: 278–280
  • Lynch S G, Rose J W, Peatjan J H. Discordance of T cell receptor β chain genes in familial multiple sclerosis. Annal Neurol 1989; 30: 402–410
  • Sherritt M A, Oksenberg J R, Kerlero de Robo N, Bernard CC. Influence of HLA-DR2, HLA-DPw4 and T-cell receptor chain genes on the susceptibility to multiple sclerosis. International Immunol 1992; 4: 177–181

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