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Original Article

Glycolipids as the Major Autoantigens of Cytoplasmatic Islet Cell Antibodies

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Pages 145-151 | Received 07 Feb 1995, Published online: 07 Jul 2009

References

  • Andreani D., Di Mario U., Pozzilli P. Prediction, Prevention, and Early Intervention in Insulin-Dependent Diabetes. Diabetes/Metabolism Reviews 1991; 7: 61–67
  • Bottazzo G. F., Florin-Christensen A., Doniach D. Islet cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies. Lancet 1974; ii: 1279–1283
  • McCuish A. C., Barnes E. W., Irvine W. J., Duncan J. P. Antibodies in Pancreatic islet cells in insulin-dependent diabetes with coexistent autoimmune disease. Lancet 1974; ii: 1529–1532
  • Colman P. G., Nayak R. C., Campbell A. L., Eisenbarth G. S. Binding of cytoplasmic islet cell antibodies is blocked by human pancreatic glycolipid extracts. Diabetes 1985; 37: 645–652
  • Nayak R. S., Omar M. A. K., Rabizadeh A., Srikanta S, Eisenbarth G. S. “Cytoplasmic” islet cell antibodies: evidence that the target antigen is a sialoglycoconjugate. Diabetes 1985; 34: 617–619
  • Portoukalian J., Rebbaa A., Thivolet C. Detection on thin layer plates of antibodies to human pancreatic gangliossides in the sera of type 1 diabetes patients. Diabetes, 39: 247A
  • Previti M., Tiberti C., Dotta F., Lenti L., Pontieri G. M., Andreani D., Di Mario U. Ganglioside characterization of human and rat pancreas: their role in endocrine auto-4immunity. J. Endocrinol. Invest 1990; 13: 63
  • Portoukalian J., Rebbaa A., Thivolet C. H. Detection on thin layer plates of autoantibodies to human pancreatic fucogangliosides in the sera of ICA positive type 1 diabetic patients. Diabetologia. 1990; 33: 155A
  • Cabrera E., Fernandez L. E., Carr A., Marquina G., Valiente O., Uriarte A., Rynmark B. M., Fredman P., Svennerholm L. Which glycolipids are the autoantigens of cytoplasmatic islet cell antibodies?. Acta Diabetologica. 1992; 29: 70–74
  • Harrison L. C. Multiple islet antigens in IDDM: order out of chaos?. International diabetes monitor 1992; 4: 1–6
  • Feizi T. Demonstration by monoclonal antibodies that carbohidrate structures of glycoproteins and glycolipids are oncodevelopmental antigens. Nature 1985; 314: 53–56
  • Hakomori S. I. Glycolipids in cellular interaction, differentiation, and oncogenesis. Ann. Rev. Biochem. 1981; 50: 733–744
  • Marcus D. M. A review of the immunogenic and immunomodulatory of glycosphingolipids. Mol. Immunol. 1984; 21: 1083–1092
  • Ariga T., Yoshida T., Mimori T., Yu R. K. Autoantibodies against Forssman glycolipids in Graves' disease and Hashimoto's thyroiditis. Clin. exp. Immunol. 1991; 86: 483–488
  • Buchard K., Josefsen K., Rygaard J., Spitalnik S. L. Pancreatic islet cell epitope recognized by an anti-sulphatide monoclonal antibody. APMIS 1991; 99: 1151–1156
  • Gianani R., Pugliese A., Bonner-Weir S., Shiffrin Soeldner J. S., Erlich Awdeh Z., Alper C. A., Jackson R. A., Eisenbarth G. S. Prognostically Significant Heterogeneity of cytoplasmic islet cell antibodies in relatives of patients with type 1 diabetes. Diabetes 1992; 41: 347–353
  • Bottazzo G. F., Genovese S., Bosi E., Dean B. M., Christie M. R., Bonifacio E. Novel considreation on the anti-body/autoantigen system in type 1 (insulin-dependent) diabetes mellitus. Ann. Med. 1991; 23: 453–461
  • Rotella C. M., Dotta F., Mannucci E., Di Mario U. Autoantigens in thyroid and islet autoimmunity: similarities and differences. Autoimmunity 1992; 12: 223–237
  • Svennerholm L. Quantitative estimation of sialic acids. A colorimetric resorcinol-hydrochloric acid method. Biochem Biophys Act 1957; 24: 604–608
  • Svennerholm L., Fredman P. A procedure for the quantitative isolation of brain gangliosides. Biochem. Biophys. Act. 1980; 617: 97–109
  • Bottazzo G. F., Gorsuch A. N., Dean B. M., Cubworth A. G., Doniach D. Complement-fixing islet cell antibodies in type 1 diabetes: possible monitors of active B cell damage. Lancet 1980; I: 668–672
  • Fulthrope A. J., Roitt I. M., Doniach D., Couchman K. A stable sheep cell preparation for detecting thyro-globulin autoantibodies and its clinical applications. J. Clin. Pathol. 1961; 14: 654–660
  • Vardi P., Dib S. A., Tuttleman M., Connelly J. E., Grinbergs M., Rabizadeh A., Riley W. J., MacLaren N. K., Eisenbarth G. S., Soeldner J. S. Competitive insulin autoantibody assay: prospective evaluation of subjects at high risk for development of type i diabetes mellitus. Diabetes 1987; 36: 1286–1291
  • Scott-Morgan L., Keller U., Heitz P., Mirza I., Diaz J. L., Casey C., Wilkin T. Insulin autoantibodies (IAA) may cause false positive islet cell antibody (ICA) results in the indirect immunofluorescence test. Diabetes Research 1988; 8: 45–8
  • Riley W. J., Maclaren N. K. Islet cell autoantibodies. The endocrine pancreas, E. Samols. Raven Press, New York, 409–422
  • MacLaren N. K., Kaufman D. L., Atkinson M. A., Muir A., Holmes L., Newman D., Tobin A. J. A subset of islet cell cytoplasmic autoantibodies (ICA) in insulin dependent diabetes (IDD) are reactive to glutamate decarboxylase (GAD). Diabetes 1992; 41: 3–8A
  • Atkinson M. A., Kaufman D. L., Newman D., Tobin A. J., MacLaren N. K. Islet cell cytoplasmatic autoantibody reactivity to glutamate decarboxylase in insulin-dependent diabetes. J. Clin. Invest. 1993; 91: 350–356
  • Scherbaum W. A. Cytoplasmic islet cell antibodies (ICA): towards a molecular understanding of the autoantigens. Clinical Endocrinology 1994; 40: 15–18
  • Genovese S., Bonifacio E., McNally J. M., Dean B. M., Wagner R., Bosi E., Gale E. A. M., Bottazzo G. F. Distinct cytoplasmatic islet cell antibodies with different risks for type 1 (insulin-dependent) diabetes mellitus. Diabetologia. 1992; 35: 385–388

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