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Original Article

Dilated Cardiomyopathy Defines Serum Autoantibodies Against G-Protein-Coupled Cardiovascular Receptors

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Pages 85-88 | Published online: 07 Jul 2009

References

  • Wenger N. K., Abelmann W. H., Roberts W. C. Cardiomyopathy and specific heart muscle disease. The Heart7th ed., J. W. Hurst, R. C. Schlant, C. E. Rackley, E. H. Sonnenblick, N. K. Wenger. McGraw-Hill, New York 1990; 1278–1347
  • Das S. K., Cassidy J. T., Petty R. E. Antibodies against heart muscle and nuclear constituents in cardiomyopathy. Am. Heart J. 1972; 83: 158–166
  • Fowlers R. S., Bieber C. P., Stinson E. B. Defective invitro suppressor cell function in idiopathic dilated cardiomyopathy. Circulation 1974; 59: 484–491
  • Jacobs B., Matsuda Y., Deodhar S., Shirey E. Cell- mediated cytotoxicity to cardiac cells of lymphocytes from patients with primary myocardial diseases. Am. J. Clin. Pathol. 1979; 72: 1–4
  • Caforio A. L. P., Bonifacio E., Stewart J. T., Neglia D., Parodi O., Bottazzo G. F., McKenna W. J. Novel organ-specific circulating cardiac autoantibodies in dilated cardiomyopathy. J. Am. Coll. Cardiol. 1990; 15: 1527–1534
  • Schultheiss H. P., Schwimmbeck P., Bolte H. D., Kligenberg M. The antigenic characteristics and the significance of adenine nucleotide translocator as a major autoantigen to antimitochondrial antibodies in dilated cardiomyopathy. Adv. Myocardiol. 1985; 6: 311–327
  • Magnusson Y., Marullo S., Höyer S., Waagstein F., Andersson B., Vahlne A., Guillet J., Strosberg A. D., Hjalmarson Å., Hoebeke J. Mapping of a functional autoimmune epitope on the β1-adrenergic receptor in patients with idiopathic dilated cardiomyopathy. J. Clin. Invest. 1990; 86: 1658–1663
  • Fu L. X. M., Magnusson Y., Bergh C., Liljeqvist J. A., Waagstein F., Hjalmarson A., Hoebeke J. Localization of functional autoimmune epitope on the muscarinic acetylcholine reccptor-2 in patients with idiopathic dilated cardiomyopathy. J. Clin. Invest. 1993; 91: 1964–1968
  • Fu L. X. M., Wallukat G., Hjalmarson A., Hoebeke J. Agonist-like activity of anti-peptide antibodies directed against an epitope on the heart muscarinic acetylcholine receptor. Receptor & Channel 1994; 2: 121–130
  • Fu L. X. M., Wallukat G., Hjalmarson A., Hoebeke J. Characterization of anti-peptide antibodies directed against an extracellular immunogenic epitope on the human α1- adrenergic receptor. Clin. Exp. Immunol. 1994; 97: 146–151
  • Bergsma D. J., Ellis C., Kumar C., et al. Cloning and characterization of a human angiotensin II type 1 receptor. Biochem. Biophy. Res. Comm. 1992; 183: 989–995
  • Sterin-Borda L., Fink S., Diez C., Cossio P., Dee M. M. Beta-adrenergic effect of antibodies from chagasic patients and normal human lymphocytes on isolated rat atria. Clin. Exp. Immunol. 1982; 50: 534–540
  • Borda E., Paswal J., Cossio P., DeLa Vega M., Arana R., Sterin-Borda L. A circulating IgG in Chagas' disease which binds to β-adrenoceptors of myocardium and modulates their activity. Clin. Exp. Immunol. 1984; 57: 679–686
  • Limas C. J., Goldenberg I. F., Limas C. Autoantibodies against β-adrenoceptors in human idiopathic dilated cardiomyopathy. Circ. Res. 1989; 64: 97–103
  • Wallukat G., Morwinski M., Kowai K., Rorster A., Boewer V., Wollenberger A. Autoantibodies against the beta-adrenergic receptor in human myocarditis and dilated cardiomyopathy; beta-adrenergic agonism without desensitization. Eur. Heart J. 1991; 12(Suppl. D)178–181
  • Fu L. X. M., Hoebeke J., Matsui S., et al. Autoantibodies against cariac G-protein coupled receptors define different populations with cardiomyopathy but not with hypertension. Clin. Immunol. Immunopathol. 1994; 72(1)15–20
  • Fu L. X. M., Herlitz H., Wallukat G., Hilme E., Hoebeke J., Hjalmarson A. A functional autoimmune epitope on human alpha I adrenergic receptors in patients with malignant hypertension. Lancet 1995; 344: 1664–1668
  • Francis G. S., Benedict C., Johnstone D. E., Kirlin P. C., Nicklas J., Linag C. -S., Kubo S. H., Rudin-Toretsky E., Yusuf S. for the SOLVD Investigators. Comparisons of neuroendocrine activation in patients with and without congestive heart failure. A substudy of the Studies of Left Ventricular Dysfunction (SOLVD). Cirulation 1990; 82: 1724–1729
  • Fu L. X. M., Liang Q. M., Waagstein F., Hoebeke J., Sylven C., Jansson E., Sotonyi P., Hjaimarson A. Increase in functional activity rather than in amount of Gi in failing human heart with dilated cardiomyopathy. Cardiovas. Res. 1992; 26: 950–955
  • Fu L. X. M., Waagstein F., Hjalmarson A. An overview of β-adrenoceptor signal transduction system: desensitization in heart failure and effect of β-blackade. Intern. J. Cardiol. 1991; 30: 261–268
  • Porter T. R., Eckberg D. L., Fritsch J. M., Rea R. F., Beightol L. A., Schmedtje J. F., Mohanty P. K. Autonomic pathophysiology in heart failure patients: Sympathetic-cholinergic interrelations. J. Clin. Invest. 1990; 85: 1362–1371

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