56
Views
42
CrossRef citations to date
0
Altmetric
Original Article

Characterization of T Cell Receptor Repertoire and Anti-Ro/SSA Autoantibodies in Relation to Sialadenitis of NOD Mice

, , , &
Pages 9-16 | Received 13 Sep 1995, Published online: 07 Jul 2009

References

  • Makino S., Kunimoto K., Muraoka Y., Mizushima Y., Katagiri K., Tochino Y. Breeding of non-obese, diabetic strain of mice. Exp. Anim. 1980; 29: 1–13
  • Miyagawa J-i., Hanafusa T., Miyazaki A., Yamada K., Fujino-Kurihara Nakajima H., et al. Ultrastructural and immunocytochemical aspects of lymphocytic submandibulitis in the non-obese diabetic (NOD) mouse. Virchows Arch. [Cell Pathol] 1986; 51: 215–225
  • Goillot E., Mutin M., Touraine J-L. Sialadenitis in nonobese diabetic mice: Transfer into syngenic healthy neonates by splenic T lymphocytes. Clin. Immunol. Immunopathol. 1991; 59: 462–473
  • Humphreys-Beher M. G., Hu Y., Wang P-L., Purushotham K. R. Utilization of the non-obese diabetic (NOD) mouse as an animal model for the study of secondary Sjögren's syndrome. The lacrimal gland, tear film and dry eye syndromes: Basic science and clinical relevance, D. Sullivan. Plenum Press, New York 1994; Vol 350: 631–636
  • Tan E. M. Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology. Adv. Immunol. 1989; 44: 93–151
  • Humphreys-Beher M. G., Brinkley L., Purushotham K. R., Wang P-L., Nakagawa Y., Dusek D., et al. Characterization of antinuclear autoantibodies present in the serum from nonobese diabetic (NOD) mice. Clin. Immunol. Immunopathol. 1993; 68: 350–356
  • Acha-Orbea H., Mitchell D. J., Timmermann L., Wraith D. C., Tausch G. S., Waldor M. K., et al. Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention. Cell 1988; 54: 263–273
  • Urban J. L., Kumar V., Kono D. H., Gomez C., Horvath S. J., Clayton J., et al. Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy. Cell 1988; 54: 577–592
  • Haqqi T. M., Anderson G. D., Banerjee S., David C. S. Restricted heterogeneity in T-cell antigen receptor Vβ gene usage in the lymph nodes and arthritic joints of mice. Proc. Natl Acad. Sci. USA 1992; 89: 1253–1255
  • Chiocchia G., Boissier M-C., Fournier C. Therapy against murine collagene-induced arthritis with T cell receptor Vβ-specific antibodies. Eur. J. Immunol. 1991; 21: 2899–2905
  • Paliard X., West S. G., Lafferty J. A., Clements J. R., Kappler J. W., Marrack P., et al. Evidence for the effects of a superantigen in rheumatoid arthritis. Science 1991; 253: 325–329
  • Acha-Orbea H., Mitchell D. J., Timmermann L., Wraith D. C., Tausch G. S., Waldor M. K., et al. Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention. Cell 1988; 54: 263–273
  • Skarstein K., Holmdahl R., Johannessen A. C., Jonsson R. Oligoclonality of T cells in salivary glands of autoimmune MRL/lpr mice. Immunology 1994; 81: 497–501
  • Wahren M., Skarstein K., Blange I., Pettersson I, Jonsson R. MRL/lpr mice produce anti-Ro 52000 MW antibodies: detection, analysis of specificity and site of production. Immunology 1994; 83: 9–15
  • Jonsson R., Tarkowski A., Bäckman K., Holmdahl R., Klareskog L. Sialdenitis in the MRL-1 mouse: Morphological and immunohistoehemical characterization of resident and infiltrating cells. Immunology 1987; 60: 611–616
  • Pierres A., Naquet P., Van Agthoven A., Bekkhucha F., Denizot F., Mishal Z., et al. A rat anti-mouse T4 monoclonal antibody (H129.19) inhibits the proliferation of Ia-reactive T cell clones and delineates two phenotypically distinct (T4+, Lyt-2,3−, and T4−, Lyt-2,3+) subsets among anti-la cytolytic T cell clones. J. Immunol. 1984; 132: 2775–2782
  • Ledbetter J. A., Herzenberg L. A. Xenogenic monoclonal antibodies to mouse lymphoid differentiation antigens. Immunol. Rev. 1979; 47: 63–90
  • Springer T., Galfré G., Secher D. S., Milstein C. Mac-1: a macrophage differentiation antigen identified by monoclonal antibody. Eur. J. Immunol. 1979; 9: 301–306
  • Kubo R. T., Born W., Kappler J. W., Marrack P., Pigeon M. Characterization of a monoclonal antibody which detects all murine αβ T cell receptors. J. Immunol. 1989; 142: 2736–2742
  • Goodman T., Le Francois L. Intraepithelial lymphocytes: Anatomical site, not T cell receptor form, dictates phenotype and function. J. Exp. Med. 1989; 170: 1569–1581
  • Pullen A. M., Potts W., Wakeland E. K., Kappler J., Marrac P. Surprisingly uneven distribution of the T cell receptor V beta repertoire in wild mice. J. Exp. Med. 1990; 171: 49–62
  • Tomonari K., Lovering E., Spencer S. Correlation between the Vβ4+CD8+ T cell population and the H-2d haplotype. Immunogen 1990; 31: 333–339
  • Acha-Orbea H., Zinkernagel R. M., Hengartner H. Cytotoxic T-cell clone specific monoclonal antibodies used to select clonotypic antigen-specific cytotoxic T cells. Eur. J. Immunol. 1985; 15: 31–36
  • Okada C. Y., Holzmann B., Guidos C., Palmer E., Weissman I. L. Characterization of a rat monoclonal antibody specific for a determinant encoded by the Vβ7 gene segment: Depletion of Vβ7+ T cells in mice with Mls-1a haplotype1. J. Immunol. 1990; 144: 3473–3477
  • Haskins K., Hannum C., White J., Roehm N., Kubo R., Kappler J., et al. The antigen-specific, major histocompatibility complex-restricted receptor on T cells. VI. An antibody to a receptor allotype. J. Exp. Med. 1984; 160: 452–471
  • Tomonari K., Hederer R., Hengartner H. Positive selection of Tcrb-V10b+ T cells. Immunogen 1992; 35: 9–15
  • Tomonari K., Lovering E. T-cell receptor-specific monoclonal antibodies against a Vβ11-positive mouse T-cell clone. Immunogen. 1988; 28: 445–451
  • Hsu S-M., Raine L., Fanger H. Use of avidin-biotinperoxidase complex (ABC) in immunoperoxidase techniques: A comparison between ABC and unlabeled antibody (PAP) procedures. J. Histochem. Cytochem. 1981; 29(4)577–580
  • Wahren M., Rudén U., Andersson B., Ringertz N. R., Petersson I. Identification of antigenic regions of the human Ro 60 kDa protein using recombinant antigen and synthetic peptides. J. Autoimmunity 1992; 5: 319–332
  • Blange I., Ringertz N. R., Pettersson I. Identification of antigenic regions of the human 52 kD Ro/SS-A protein recognised by patient sera. J. Autoimmunity 1994; 7: 263–274
  • Nyman U., Ringertz N. R., Pettersson I. Demonstration of an aminoterminal La epitope recognized by human anti-La sera. Immunol. Lett. 1989; 22: 65–72
  • Goding J. W. Antibody production by hybridomas. J. Immunol. Meth. 1980; 39: 285–308
  • O'Reilly L. A., Hutchings P. R., Crocker P. R., Simpson E., Lund T., Kioussis D., et al. Characterization of pancreatic islet cell infiltrates in NOD mice: effect of cell transfer and transgene expression. Eur. J. Immunol. 1991; 21: 1171–1180
  • Nakano N., Kikutani H., Nishimoto H., Kishimoto T. T cell receptor V gene usage of islet β cell-reactive T cells is not restricted in non-obese diabetic mice. J. Exp. Med. 1991; 173: 1091–1097
  • Maeda T., Sumida T., Kurasawa K., Tomioka H., Itoh I., Yoshida S., et al. T-lymphocyte-receptor repertoire of infiltrating T lymphocytes into NOD mouse pancreas. Diabetes 1991; 40: 1580–1585
  • Waters S. H., O'Neil J. J., Melican D. T., Appel M. C. Multiple TCR Vβ usage by infiltrates of young NOD mouse islets of Langerhans: A polymerase chain reaction analysis. Diabetes 1992; 41: 308–312
  • Candéias S., Katz J., Benoist C., Mathis D, Haskins K. Islet-specific T-cell clones from nonobese diabetic mice express heterogeneous T-cell receptors. Proc. Natl Acad. Sci. USA 1991; 88: 6167–6170
  • Bacelj A., Charlton B, Mandel T. E. Prevention of cyclophosphamide-induced diabetes by anti-Vβ8 T-lymphocyte-receptor monoclonal antibody therapy in NOD/wehi mice. Diabetes 1989; 38: 1492–1495
  • Edouard P., Thivolet C., Bedossa P., Olivi M., Legrand B., Bendelac A., et al. Evidence for a preferential Vβ usage by the T cells which adoptively transfer diabetes in NOD mice. Eur. J. Immunol. 1993; 23: 727–733
  • Sarukhan A., Gombert J-M., Olivi M., Bach J-F., Carnaud C., Garchon H-J. Anchored polymerase chain reaction based analysis of the Vβ repertoire in the non-obese diabetic (NOD) mouse. Eur. J. Immunol. 1994; 24: 1750–1756
  • Mountz J. D., Smith T. M., Toth K. S. Altered expression of self-reactive T cell receptor Vβ regions in autoimmune mice. J. Immunol. 1990; 144: 2159–2166
  • Kurasawa K., Sakamoto A., Maeda T., Sumida T., Ito I., Tomioka H., et al. Short-term administration of anti-L3T4 moAb prevents diabetes in NOD mice. Clin. Exp. Immunol. 1993; 91: 376–380
  • Matsuoka N., Bernard N., Concepcion E. S., Graves P. N., Ben-Nun A, Davies T. F. T-cell receptor V region β-chain gene expression in the autoimmune thyroiditis of non-obese diabetic mice. J. Immunol. 1993; 151: 1691–1701
  • Baxter A. G., Horsfall A. C., Healey D., Ozegbe P., Day S., Williams D. G. Mycobacteria precipitate an SLE-like syndrome in diabetes-prone NOD mice. Immunology 1994; 83: 227–231

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.