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Original Article

Cyclins and Autoimmunity: Cyclin B1 Gene Expression and Restriction Fragment Length Polymorphism in Lupus-Prone Mice

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Pages 17-26 | Received 04 Sep 1995, Published online: 07 Jul 2009

References

  • Murray A. W. Creative blocks: Cell-cycle checkpoints and feedback controls. Nature (Lond.) 1992; 359: 599–604
  • Hunter T. Braking the cycle. Cell 1993; 75: 839–841
  • Hunter T., Pines J. Cyclins and cancer II: Cyclin D and cyclin dependent kinase inhibitors come of age. Cell 1994; 79: 573–582
  • Koff A., Cross F., Fishe A., Schumacher J., Leguellec K., Philippe M., Roberts J. M. Human cyclin E., a new cyclin that interacts with two members of the CDC2 gene family. Cell 1991; 66: 1217–1228
  • Ajchenbaum F., Ando K., Decaprio A., Griffin J. D. Independent regulation of human D-type cyclin gene expression during G1 phase in primary human T lymphocytes. J. Biol. Chem. 1993; 268: 4113–4119
  • Sheer C. J. Mammalian G1 cyclins. Cell 1993; 73: 1059–1065
  • Pines J., Hunter T. Human cyclin A is adenovirus E1A-associated protein p60, and behaves differently from cyclin B. Nature (Lond.) 1990; 346: 760–763
  • Nasmyth K. A. Far-reaching discoveries about the regulation of START. Cell 1990; 63: 1117–1120
  • Nurse P. Universal control mechanisms regulating onset of M-phase. Nature (Lond.) 1990; 344: 503–508
  • Murray A. W., Solomon M. J., Kirschner M. W. The role of cyclin synthesis and degradation in the control of maturation promoting factor activity. Nature (Lond.) 1991; 349: 132–138
  • Galaktionov K., Beach D. Specific activation of cdc25 tyrosine phosphatase by B-type cyclins: Evidence for multiple roles of mitotic cyclins. Cell 1991; 67: 1181–1194
  • Westedorf J. M., Swenson K. I., Ruderman J. V. The role of cyclin B1 in meiosis. J. Cell. Biol. 1989; 108: 1431–1444
  • Gong J., Ardelt B., Traganos F., Darzynkiewicz Z. Unscheduled expression of cyclin B1 and cyclin E in several leukemic and solid tumor cell lines. Cancer Res. 1994; 54: 4285–4288
  • Thomas T., Thomas T. J. Regulation of cyclin B1 by estradiol and polyamines in MCF 7 breast cancer cells. Cancer Res. 1994; 54: 1077–1084
  • Glotzer M., Murray A. W., Kirschner M. W. Cyclin is degraded by the ubiquitin pathway. Nature (Lond.) 1991; 349: 132–138
  • Chapman D. L., Wolgemuth D. J. Identification of a mouse B-type cyclin which exhibits developmentally regulated expression in germ line. Mol. Rep. Dev. 1992; 33: 259–269
  • Chapman D. L., Wolgemuth D. J. Isolation of murine cyclin B2 cDNA and characterization of the lineage and temporal specificity of expression of the B1 and B2 cyclins during oogenesis, spermatogenesis and early embryogenesis. Development 1993; 118: 229–240
  • Firpo E. J., Koff A., Solomon M. J., Roberts J. M. Inactivation of cdk2 during interleukin-2-induced proliferation of human T lymphocytes. Mol. Cell. Biol. 1994; 14: 4889–4901
  • Kim Y. H., Proust J. J., Buchholz M. J., Chrest F. J., Nordin A. A. Expression of the murine homologue of the cell cycle control protein p34cdc2 in T lymphocytes. J. Immunol. 1992; 149: 17–23
  • Roy-Walker P., Kwast-Welfeld J., Gourdeau H., Leblanc J., Neugebauer W., Sirkoska M. Relationship between apoptosis and the cell cycle in lymphocytes: Roles of protein kinase C., tyrosine phosphorylation, and AP-1. Exp. Cell. Res. 1993; 207: 142–151
  • Boehme S. A., Lenardo M. J. Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle. Eur. J. Immunol. 1993; 23: 1532–1534
  • Zhu L., Anasetti C. Cell cycle control of apoptosis in human leukemic T cells. J. Immunol. 1995; 154: 192–200
  • Pisetsky D. S. Systemic lupus erythematosus. Curr. Opin. Immunol. 1991; 3: 917–923
  • Tan E. M., Chan E. K. Molecular biology of autoantigens and new insights into autoimmunity. Clin. Invest. 1993; 71: 327–330
  • Andrews B. S., Eisenberg R. A., Theofilopoulos A. N., Izui S., Wilson C. B., McConahey P. J., Murphy E. D., Roths J. B., Dixon F. J. Spontaneous murine lupus-like syndrome: Clinical and immunopathological manifestations in several strains. J. Exp. Med. 1978; 148: 1198–1207
  • Steinberg A. D., Raveche E., Laskin C. A., Smith H. A., Santoro T., Miller M. L., Plotz P. H. Systemic lupus erythematosus: Insights from animal models. Ann. Internal. Med. 1984; 100: 714–727
  • Watanabe-Fukunaga R., Brannan C. I., Copeland N. A., Nagata S. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature (Lond.) 1992; 356: 314–317
  • Itoh N., Yonehara S., Ishii A., Yonehara M., Mizushima S.-I., Sameshima M., Hase A., Seto Y. and Nagata S: The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis. Cell 1991; 66: 233–243
  • Nagata S., Suda T. Fas and Fas ligand: Ipr and gld mutations. Immunol. Today 1995; 16: 39–43
  • Giese T., Davidson W. F. Evidence for early onset, polyclonal activation of T cell subsets in mice homozygous for lpr. 1 Immunol. 1992; 149: 3097–4009
  • Merino R., Iwamoto M., Fossati L., Izui S. Polyclonal B cell activation arises from different mechanisms in lupus-prone (NZB × NZW)F1 and MRL/MpJ-/pr//pr mice. J. Immunol. 1993; 151: 6509–6516
  • Raveche E. S., Steinberg A. D., DeFranco A. L., Tjio J.-T. Cell cycle analysis of lymphocyte activation in normal and autoimmune strains of mice. J. Immunol. 1982; 129: 1219–1226
  • Steinberg A. D., Roths J. B., Murphy E. T., Steinberg R. T., Raveche E. S. Effects of thymectomy or androgen administration upon the autoimmune disease of MRL-lpr/lpr mice. J. Immunol. 1982; 125: 871–873
  • Zhou T., Bluethmann H., Eldridge J., Berry K., Mountz J. D. Origin of CD4−CD8−B220+ T cells in MRL-lpr/lpr mice. J. Immunol. 1993; 150: 3651–3667
  • Chomczynski P. A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples. Bio Techniques 1993; 15: 532–537
  • Gross-Bellard M., Oudet P., Chambon P. Isolation of high molecular-weight DNA from mammalian cells. Eur. J. Biochem. 1973; 36: 32–38
  • Dean P. N. Techniques in Cell Cycle Research: Data analysis in cell kinetics, J. W. Gray, Z. Darzynkiewicz. Human Press, Clifton, NJ 1987; 207–253
  • Hanley-Hyde J., Frederic M., Sodofsky M., Huppi K., Krall M., Kozak C. A., Mock B. Expression of murine cyclin B1 mRNAs and genetic mapping of related genomic sequences. Genomics 1992; 13: 1018–1030
  • Lock L. F., Pines J., Hunter T., Gilbert D. J., Gopalan G., Jenkins N. A., Copeland N. G., Donovan P. J. A single cyclin A gene and multiple cyclin B1-related sequences are dispersed in the mouse genome. Genomics 1992; 13: 415–424
  • Maity A., McKenna W. G., Muschel R. J. Evidence for post-transcriptional regulation of cyclin B1 mRNA in the cell cycle and following irradiation in HeLa cells. EMBO J. 1995; 14: 603–609
  • Thomas T. J., Gunnia U. B., Thomas T. Genetic variations of polyamine biosynthesis in autoimmune mice. Arthritis Rheum. 1990; 33: S80, (Abstract)
  • Thomas T. J., Gunnia U. B., Thomas T. Reversal of the abnormal development of T cell subpopulation in the thymus of autoimmune MRL-lpr/lpr mice by a polyamine biosynthesis inhibitor. Autoimmunity 1992; 13: 275–283
  • Itoh N., Tsujimoto Y., Nagata S. Effect of bcl-2 on Fas antigen-mediated cell death. J. Immunol. 1993; 151: 621–627
  • Smith M. J., Trapani J. A. Granzymes: exogenous proteinases that induce target cell apoptosis. Immunol. Today 1995; 16: 202–206
  • Meikrantz W., Gisselbrecht S., Tarn S., Schlegel R. Activation of cyclin A dependent protein kinase during apoptosis. Proc. Natl Acad. Sci. USA 1994; 91: 3754–3758
  • Brunner T., Mogil R. J., LaFance D., Yoo N. J., Mahboubi A., Echeverri F., Martin S. J., Force W. R., Lynch D. H., Ware C. F., Green D. R. Cell-autonomous Fas (CD95)/Fas ligand interaction mediates activation-induced apoptosis in T-Cell hybridomas. Nature (Lond.) 1995; 373: 441–444
  • Smith K. A. Interleukin-2; Inception, impact, and implication. Science 1986; 230: 1169–1176
  • Stern J. B., Smith K. A. Interleukin-2 induction of T-cell G1 progression and c-myb expression. Science 1986; 233: 203–206
  • Altman A., Theofilopoulos A. N., Weiner R., Katz D. H., Dixon F. J. Analysis of T cell function in autoimmune murine strains: defects in production and responsiveness to interleukin 2. J. Exp. Med. 1981; 154: 791–808
  • Wofsy D., Murphy E. D., Roths J. B., Dauphinee M. J., Kipper S. B., Talal N. Deficient interleukin-2 activity in MRL/MpJ and C57BL/6J mice bearing the lpr gene. J. Exp. Med. 1981; 154: 1671–1680
  • Mountz J. D., Steinberg A. D., Klinman D. M., Smith H. R., Mushinski J. F. Autoimmunity and increased c-myb transcription. Science 1984; 226: 1087–1090
  • Mountz J. D., Steinberg A. D. Studies of c-myb gene regulation in MRL-lpr/lpr mice-Identification of a 5 ' c-myb nuclear protein binding site and high levels of binding factors in nuclear extracts of lpr/lpr lymph node cells. J. Immunol. 1989; 142: 328–335
  • Izui S., Kelley V. E., Masuda K., Yoshida H., Roth J. B., Murphy E. D. Induction of various autoantibodies by mutant gene lpr in several strains of mice. J. Immunol. 1984; 133: 227–233
  • Kakkaniah V. N., Pyle R. H., Nagarkatti M., Nagarkatti P. S. Evidence for a major alterations in the thymocyte subpopulations in murine models of autoimmune disease. J. Autoimmunity 1990; 3: 271–288
  • Theofilopoulos A. N., Kofler R., Singer P. A., Dixon F. J. Molecular genetics of murine lupus models. Adv. Immunol. 1989; 46: 61–109
  • Tsao Y. P., D'Arpa P., Liu L. F. The involvement of active DNA synthesis in camptothecin-induced G2 arrest: altered regulation of p34cdc2/cyclin B1. Cancer Res. 1992; 52: 1823–1829

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