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Original Article

Anti-Ganglioside Antibodies in New Onset Type 1 Diabetic Patients and High Risk Subjects

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Pages 43-48 | Received 23 Oct 1995, Published online: 07 Jul 2009

References

  • Hakomori S. Glycosphingolipids in cellular interaction, differentiation and oncogenesis. Annu. Rev. Biochem. 1981; 50: 733–764
  • Endo T., Scott D. D., Stewart S., Kundu S. K., Marcus D. Antibodies to glycosphingolipids in patients with multiple sclerosis and SLE. J. Immunol. 1984; 32: 1793–1797
  • Hirano T., Hashimoto H., Shiokawa Y. Anti-glycolipid autoantibodies detected in the sera from systemic lupus erythematosus patients. J. Clin. Invest. 1980; 66: 1437–1442
  • Gillard B. K., Thomas J. W., Nell N. J., Marcus D. M. Antibodies against ganglioside GT3 in the sera of patients with type 1 diabetes mellitus. J. Immunol. Methods. 1989; 142: 3826–3832
  • Castano L., Eisenbarth G. S. Type 1 diabetes: a chronic autoimmune disease of the human, mouse and rat. Ann. Rev. Immunol. 1990; 8: 647–679
  • Atkinson M. A., MacLaren N. K. Mechanism of disease: the pathogenesis of insulin-dependent diabetes mellitus. New Engl. J. Med. 1994; 331: 1428–1435
  • Bottazzo G. F., Florin-Christensen A., Doniach D. Islet cell antibodies in diabetes mellitus with autoimmune poly-endocrine deficiency. Lancet 1974; ii: 1279–1283
  • Baekkeskov S., Aanstoot H. J., Christgau S., Reetz A., Solimena M., Cascalho M., Folli F., Richter-Olesen H., De Camilli P. Identification of the 64K autoantigen in insulin dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase. Nature 1990; 347: 151–156
  • Palmer J. P., Asplin C. M., demons P., Lyen K., Tatpati O., Raghu P. K., Paquette T. L. Insuli antibodies to insulin-dependent diabetics before insulin treatment. Science 1983; 222: 1337–1339
  • Pietropaolo M., Castaño L., Babu S., Buelow R., Kuo Y.-L.S., Martin S., Martin A., Powers A. C., Prochazka M., Naggert J., Leiter E. H., Eisenbarth G. S. Islet cell autoantigen 69kD (ICA 69) Molecular cloning and characterization of a novel diabetes-associated autoantigen. J. Clin. Invest. 1993; 92: 359–371
  • Castaño L., Russo E., Zhou L., Lipes M. A., Eisenbarth G. S. Identification and cloning of a granule autoantigen (carboxpeptidase H) associated with type I diabetes. J. Clin. Endocrinol. Metab. 1991; 73: 1197–1201
  • Nayak R. C., Omar M. A.K., Rabizadeh A., Srikanta S., Eisenbarth G. S. “Cytoplasmic” islet cell antibodies: evidence that the target antigen is a sialoglycoconjugate. Diabetes. 1985; 34: 617–619
  • Colman P. G., Nayak R. C., Campbell I. L., Eisenbarth G. S. Binding of “cytoplasmic” islet cell antibodies is blocked by human pancreatic glycolipid extracts. Diabetes. 1988; 37: 645–652
  • Dotta F., Colman P. G., Lombardi D., Scharp D. W., Andreani D., Pontieri G. M., Di Mario U., Lenti L., Eisenbarth G. S., Nayak R. C. Ganglioside expression in human pancreatic islets. Diabetes. 1989; 38: 1478–1483
  • Dotta F., Tiberti C., Previti M., Anastasi E., Andreani D., Lenti L., Pontieri G. M., Gianani R., Appel M. C., Eisenbarth G. S., Di Mario U. Rat pancreatic ganglioside expression: differences between a model of autoimmune islet β cell destruction and a normal strain. Clinical Immunology and Immunopathology 1993; 66: 143–149
  • Dotta F., Peterson L. B., Previti M., Metzger J., Tibreti C., Anastasi E., Zoppitelli P., Wicker L. S., Di Mario U. Pancreatic islet ganglioside expression in nonobese diabetic mice: comparison with C57BL/10 mice and changes after autoimmune β-cell destruction. Endocrinology. 1992; 130: 37–42
  • Svennerholm L. Chromatographic separation of human brain gangliosides. J. Neurochem. 1963; 10: 613–623
  • Vardi P., Dib S. A., Tuttleman M., Connelly J. E., Grinbergs M., Rabizadeh A., Riley W. J., Maclaren N. K., Eisenbarth G. S., Soeldner J. S. Competitive insulin autoantibody RIA: prospective evaluation of subjects at high risk for development of type 1 diabetes mellitus. Diabetes. 1987; 36: 1286–1291
  • Di Mario U., Perfetti R., Anastasi E., Contreas G., Crisà L., Tiberti C., Amendolea M. A., Masala C. Autoantibodies to insulin do appear in non-diabetic patients with autoimmune disorders: comparison with anti-immunoglobulin antibodies and other autoimmune phenomena. Acta Endocrinologica. (Copenh) 1990; 122: 303–308
  • Boitard C., Bonifacio E., Bottazzo G. F., Gleichmann H., Molenaar J. Immunology and Diabetes Workshop on the Standardization of Cytoplasmic Islet Cell Antibodies. New YorkUSA October, 1987
  • Senn H. J., Orth M., Fitzke E., Wieland H., Gerok W. Gangliosides in normal human serum. Eur. J. Biochem. 1989; 181: 657–662
  • Ledeen R. W. The gangliosides. Handbook of neurochemistry, A. Lajtha. Plenum Press, New York 1983; vol. 3: 41–76
  • Bartholomeusz R. K., Campbell I. L., Harrison L. C. Pancreatic islet A2B5-and 3G5-reactive gangliosides are markers of differentiation in rat insulinoma cells. Endocrinology. 1989; 124(6)2680–2685
  • Colman P. G., Nayak R. C., Campbell I. L., Eisenbarth G. S. Binding of cytoplasmic islet cell antibodies is blocked by human pancreatic glycolipid extracts. Diabetes. 1988; 37: 645–651
  • Czarniecki M. F., Thornton E. R. Carbon-13 nuclear magnetic resonances spin-lattice relaxation in the N-acylneuraminic acids. Probes for internal dynamics and conformational analysis. J. Am. Chem. Soc. 1977; 99: 8273–8278

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