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Original Article

Different HLA-DQ are Positively and Negatively Associated in Swedish Patients with Myasthenia Gravis

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Pages 59-65 | Received 03 Oct 1995, Published online: 07 Jul 2009

References

  • Conti-Troconi B. M., McLane K. E., Raftery M. A., Grando S. A., Pia Protti M. The nicotinic acetycholine receptor: structure and autoimmune pathology. Crit. Rev. Biochem. Mol. Biol. 1994; 29: 69–123
  • Willcox N. Myasthenia gravis. Curr. Op. Immunol. 1993; 5: 910–917
  • Drachman D. B. Myasthenia gravis. N Eng. J. Med. 1994; 330: 1797–1810
  • Hohfeld R., Wekerle H. The role of the thymus in myasthenia gravis. Adv. Neuroimmunol. 1994; 4: 373–386
  • Tournier-Lasserve E., Bach J.-F. The immunogenetics of myasthenia gravis, multiple sclerosis and their animal models. J. Neuroimmunol. 1993; 47: 103–114
  • Kaul R., Shenoy M., Christadoss P. The role of major histocompatibility complex genes in myasthenia gravis and experimental autoimmune myasthenia gravis pathogenesis. Adv. Neuroimmunol. 1994; 4: 387–402
  • Pirskanen R., Tiilikainen A., Hokkanen E. Histocompatibility HL-A antigens associated with myasthenia gravis. A preliminary report. Ann. Clin. Res. 1972; 4: 304–306
  • Van den Berg-Loonen E. M., Nijenhuis L. E., Engelfriet C. P., Feltkamp T. E.W., van Rossum A. L., Oosterhusi H. J.G.H. Segregation of HLA haplotypes in 100 families with a myasthenia gravis patient. J. Immunogenet. 1977; 4: 331–340
  • Kaakinen A., Pirskanen R., Tiikanen A. LD antigens associated with HL-A8 and myasthenia gravis. Tissue Antigens 1915; 6: 175–182
  • Möller E., Hammarström L., Smith E., Matell G. HL-A8 and LD-8a in patients with myasthenia gravis. Tissue Antigens 1976; 7: 39–44
  • Dawkins R. L., Christiansen F. T., Kay P. H., Garlepp M., McCluskey J., Hollingsworth P. N., Zilko P. J. Disease associations with complotypes, supratypes and haplotypes. Immunol. Rev. 1983; 70: 5–22
  • Christiansen F. T., Pollack M. S., Garlepp M. J., Dawkins R. L. Myasthenia gravis and HLA antigens in American Blacks and other races. J. Neuroimmunol. 1984; 7: 121–129
  • Chen W.-H., Chiu H.-C., Hseih R.-P. Association of HLA-Bw46DR9 combination with juvenile myasthenia gravis in Chinese. J. Neurol. Neurosurg. Psychiatry 1993; 56: 382–385
  • Chan S. H., Tan C. B., Lin Y. N., Wee G. B., Degli-Eposti M. A., Dawkins R. L. HLA and Singaporean Chinese myasthenia gravis. Int. Arch. Allergy Immunol. 1993; 101: 119–125
  • Horiki T., Inoko H., Moriuchi J., Ichikawa Y., Arimori S. Combinations of HLA-DP1 and DQB1 alleles determine susceptibility to early-onset myasthenia gravis in Japan. Autoimmunity 1994; 19: 49–54
  • Matsuki K., Juji T., Tokunaga K., Takamizawa M., Maeda H., Soda M., Nomura Y., Segawa M. HLA antigens in Japanese patients with myasthenia gravis. J. Clin. Invest. 1990; 86: 392–399
  • Mehra N. K., Ahuja G. K., Taneja V., Vaidya M. C. HLA Antigens and myasthenia gravis in north India. J. Neurol. Neurosurg. Psychiatry 1983; 46: 361–364
  • Barton E. N., Smikle M., Morgan O. S.C. Myasthenia gravis and HLA phenotypes in Jamaicans. South. Med. J. 1992; 85: 904–906
  • Compston D. A.S., Vincent A., Newsom-Davis J., Batchelor J. R. Clinical, pathological, HLA antigen and immunological evidence for disease heterogeneity in myasthenia gravis. Brain 1980; 103: 579–601
  • Vieira M. L., Caillat-Zucman S., Gajdos P., Cohen-Kaminsky S., Casteur A., Bach J.-F. Identification by genomic typing of non-DR3 HLA class II genes associated with myasthenia gravis. J. Neuroimmunol. 1993; 47: 115–122
  • Carlsson B., Wallin J., Pirskanen R., Matell G., Smith C LE. Different HLA DR-DQ associations in subgroups of idiopathic myasthenia gravis. Immunogenetics 1990; 31: 285–290
  • Spurkland A., Gilhus N. E., Rønningen K. S., Aarli J. A., Vartdal F. Myasthenia gravis patients with thymus hyperplasia and myasthenia gravis patients with thymoma display different HLA associations. Tissue Antigens 1991; 37: 90–93
  • Khalil I., Berrih-Aknin S., Lepage V., Loste M.-N., Gajdos P., Hors J., Charron D., Degos L. Trans-encoded DQαβ heterodimers confer susceptibility to myasthenia gravis disease. C. R. Acad. Sci. Paris 1993; 316: 652–660
  • Bell J., Smoot S., Newby C., Toyka K., Rassenti L., Smith K., Hohlfeld R., McDevitt H. O., Steinman L. HLA-DQ beta-chain polymorphism linked to myasthenia gravis. Lancet 1986; 1: 1058–1060
  • Christadoss P., Lindstrom J. M., Melvold R. W., Talal N. Mutation at I-Aβ chain prevents experimental autoimmune myasthenia gravis. Immunogenetics 1985; 31: 241–244
  • Oosterhuis H. J.G.H. Studies in myasthenia gravis. J. Neurol. Sci. 1964; 1: 512–546
  • Sanjeevi C. B., Seshiah V., Möller E., Olerup O. Different genetic backgrounds for malnutrition-related diabetes and Type 1 (insulin-dependent) diabetes mellitus in South Indians. Diabetologia 1992; 35: 283–286
  • Woolf B. On estimating the relation between blood group and disease. Ann. Hum. Genet. 1955; 19: 251–253
  • Waldor M. K., Sriram S., McDevitt H. O., Steinman L. In vivo therapy with monoclonal anti-I-A antibody suppresses immune response to AChR. Proc. Natl. Acad. Sci. USA 1983; 80: 2713–2717
  • Bellone M., Ostllie N., Lei S., Wu X. D., Conti-Troconi B. M. The I-Abm12 mutation, which confers resistance to experimental autoimmune myasthenia gravis, drastically affects the epitope repertoire of murine CD4 + cells sensitized to nicotinic acetylcholine receptor. J. Immunol. 1991; 147: 1484–1491
  • McIntyre K., Seidman J. G. Nucleotide sequence of mutant I-Aβbm12 gene is evidence for genetic exchange between mouse immune reponse genes. Nature 1984; 308: 551–553
  • Morita K., Moriuchi J., Inoko H., Tsuji K., Arimori S. HLA class II antigens and DNA restriction fragment length polymorphism in myasthenia gravis in Japan. Ann. Neurol. 1991; 29: 168–174
  • Degli-Esposti M. A., Andreas A., Christiansen F. T., Schalke B., Albert E., Dawkins R. L. An approach to the localization of the susceptibility genes for general myasthenia gravis by mapping recombinant ancestral haplotypes. Immunogenetics 1992; 35: 355–364
  • Oksenberg J. R., Sherritt M., Begovich A. B., Erlich H. A., Bernard C. C., Cavalli-Sforza L. L., Steinman L. T-cell receptor Vα and Cα alleles associated with multiple sclerosis and myasthenia gravis. Proc. Natl. Acad. Sci. USA 1989; 86: 988–992
  • Mantegazza R., Oksenberg J. R., Baggi F., Antozzi C., Illeni M. T., Pellegris G., Cornelio F., Steinman L. Increased incidence of certain TCR and HLA genes associated with myasthenia gravis in Italians. J. Autoimmun. 1990; 3: 431–440
  • Grünewald J., Åhlberg R., Lefvert A.-K., Dersimonian H., Wigzell H., Janson C. H. Abnormal T-cell expansion and V-gene usage in myasthenia gravis patients. Scand. J. Immunol. 1991; 34: 161–168
  • Garchon H.-J., Djabiri F., Viard J.-P., Gajdos P., Bach J.-F. Involvement of human muscle acetylcholine receptor α-subunit gene (CHRNA) in susceptibility to myasthenia gravis. Proc. Natl. Acad. Sci. USA 1994; 91: 4668–4672
  • Vincent A. Aetiological factors in development of myasthenia gravis. Adv. Neuroimmunol. 1994; 4: 355–371
  • Kockum I., Wassmuth R., Holmberg E., Michelsen B., Lernmark Å. HLA-DQ primarily confers protection and HLA-DR susceptibility in Type 1 (insulin-dependent) diabetes studied in population-based affected families and controls. Am. J. Hum. Genet. 1993; 53: 150–167
  • Sanjeevi C. B., Lybrand T. P., DeWeese C., Landin Olsson M., Kockum I., Dahlquist G., Sundkvist G., Stenger D., Lernmark Å. Polymorphic amino acid variations in HLA-DQ are associated with systematic physical property changes and occurence of insulin-dependent diabetes mellitus. Diabetes 1995; 1: 125–131

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