7
Views
3
CrossRef citations to date
0
Altmetric
Original Article

Cytotoxicity Towards Neonatal Versus Adult BB Rat Pancreatic Islet Cells

, &
Pages 93-98 | Received 10 Nov 1994, Published online: 07 Jul 2009

References

  • Scott J. The spontaneously diabetic BB rat. Sites of the defects leading to auto-immunity and diabetes mellitus. A review. Curr. Top. Microbiol-Immunol. 1990; 156: 1–14
  • Crisa L., Mordes J. P., Rossini A. A. Autoimmune diabetes meljitus in the BB rat. Diab. Metab. Rev. 1992; 8: 4–37
  • Adams T. E., Alpert S., Hanahan D. Non-tolerance and autoantibodies to a transgenic self antigen expressed in pancreatic beta cells. Nature 1987; 325: 223–228
  • Buschard K., Jørgensen M., Aæn K., Bock T., Josefsen K. Prevention of diabetes mellitus in BB rats by neonatal stimulation of beta cells. Lancet 1990; 335: 134–135
  • Bock T., Kjær T. W., Jørgensen M., Josefsen K., Rygaard J., Buschard K. Reduction of diabetes incidence in NOD mice by neonatal glucose treatment. APMIS 1991; 99: 989–992
  • Hansen A. K., Dagnæs-Hansen F. An introduction to the use of rodent models in diabetes research. Møllegaard Ltd, Bomholdtgaard Ltd., LI Skensved, Ry 1990
  • Aacn K., Rygaard J., Josefsen K., Petersen H., Brogren C. H., Horn T., Buschard K. Dependence of antigen expression on functional state of beta-cells. Diabetes 1990; 39: 697–701
  • Sutton R., Peters M., McShane P., Gray D. W.R., Morris P. J. Isolation of rat pancreatic islets by ductal injection of collagenase. Transplant 1986; 42: 689–691
  • Josefsen K., Hansen W. A., Kjær T., Jørgensen M., Horn T., Berggren P-O., Porsman P., Buschard K. Optimizing fluorescence activated cell sorting (FACS) of pancreatic endocrine cells. Diabetes 1990; 39(supplement 1)149A, [Abstract]
  • Nakamura N., Woda B. A., Tafuri A., Greiner D. L., Reynolds C. W., Ortaldo J., et al. Intrinsic cytotoxicity of natural killer cells to pancreatic islets in vitro. Diabetes 1990; 39: 836–843
  • Charles A. M., Suzuki M., Waldeck N., Dodson L. E., Slater L., Ong K., et al. Immune islet killing mechanisms associated with insulin-dependent diabetes: in vitro expression of cellular and antibody-mediated islet cell cytotoxicity in humans. J. Immunol. 1983; 130: 1189–1194
  • Weringer E. J., Like A. A. Diabetes mellitus in the BB/W rat. Insulitis in pancreatic islet grafts after transplantation in diabetic recipients. Am. J. Pathol. 1986; 125: 107–112
  • Prowse S. J., Bellgrau D., Lafferty K. J. Islet allografts are destroyed by disease occurence in the spontaneously diabetic BB rat. Diabetes 1986; 35: 110–114
  • Hegre O. D., Enriquez A. J., Ketchum R., Weinhaus A. J., Serie J. R. Islet transplantation in spontaneously diabetic BB/Wor rats. Diabetes 1989; 38: 1148–1154
  • Weringer E. J., Like A. A. Immune attack on pancreatic islet transplants in the spontanously diabetic biobreeding/Worcester (BB/W) rat is not MHC restricted. J. Immunol. 1985; 134: 2383–2386
  • Rossini A. A., Handler E. S., Mordes J. P. The BB rat as an animal model of auto-immune diabetes mellitus. The immunology of diabetes mellitus, M. A. Jaworski, G. D. Molnar, R. V. Rajotte, B. Singh. Excerpta Medica. 1986, Int.-congress series 717. 1991
  • Ihm S. H., Lee K-U., Yoon J. W. Studies on Autoimmunity for initiation of Beta-cell destruction. VII. Evidence for antigenic changes on beta-cells leading to autoimmune destruction of Beta-cells in BB rats. Diabetes 1991; 40: 269–274
  • Ko I-Y., Yoon J-W. Delayed expression of islet cell specific autoantigen in BB rats may be responsible for the initiation of autoimmune type I diabetes. Diabetes 1991; 40(supplement 1)54A, [Abstract]
  • Ko I. Y., Jun H. S., Kim G. S., Yoon J. W. Studies on autoimmunity for initiation of beta-cell destruction X. Delayed expression of a membrane-bound islet cell-specific 38 kDa autoantigen that precedes insulitis and diabetes in the diabetes-prone BB rat. Diabetologia 1994; 37: 460–465
  • Yoneda R., Yokono K., Okamoto N., et al. Neonatal Pancreatic Beta Cells Are Opened for Cytotoxic T Lymphocytes. Diabetes 1994; 43(supplement 1)23A, [Abstract]

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.