7
Views
2
CrossRef citations to date
0
Altmetric
Original Article

Restricted Heterogeneity and Changing Spectrotypes in Autoantibodies to La/SS-B

, , , &
Pages 229-236 | Received 05 Mar 1996, Accepted 08 Jul 1996, Published online: 07 Jul 2009

References

  • Tan E. M. Antinuclear antibodies: diagnostic markers for autoimmune diseases and probes for cell biology. Adv. Immunol. 1989; 44: 93–151
  • Kato T., Yamamoto K., Takeuchi H., Okubo M., Hara E., Nakada S., et al. Identification of a universal B cell epitope on DNA topoisomerase I, an autoantigen associated with scleroderma. Arthritis Rheum. 1993; 36: 1580–1587
  • Williamson A. R. Isoelectric focusing of immunoglobulins, D. M. Weir. Handbook of experimental immunology, Blackwell, Oxford 1978; 9.1–9.31
  • Miller F. W., Twitty S. A., Biswas T., Plotz P. H. Origin and regulation of a disease-specific autoantibody response. Antigenic epitopes, spectrotype stability, and isotype restriction of anti-Jo-I autoantibodies. J. Clin. Invest. 1990; 85: 468–475
  • Eisenberg R. A., Dyer K., Craven S. Y., Fuller C. R., Yount W. J. Subclass restriction and polyclonality of the systemic lupus erythematosus marker antibody antibody anti-Sm. J. Clin. Invest. 1985; 75: 1270–1277
  • Eisenberg R. A., Earnshaw W. C., Bordwell B. J., Craven S. Y., Check R., Rothfield N. F. Isotype analysis of the anti-CENP-B anticentromere autoantibody: evidence for restricted clonality. Arthritis Rheum. 1989; 32: 1315–1318
  • Bini P., Chu J. L., Okolo C., Elkon K. Analysis of autoantibodies to recombinant La(SS-B) peptides in systemic lupus erythematosus and primary Sjogren's syndrome. J. Clin. Invest. 1990; 85: 325–333
  • Bonfa E., Chu J. L., Brot N., Elkon K. B. Lupus anti-ribosomal P peptide antibodies show limited he-terogeneiety and are predominantly of the IgG1 and IgG2 subclasses. Clin. Immunol. Immunopathol. 1987; 45: 129–138
  • Sestak A. L., Harley J. B., Yoshida S., Reichlin M. Lupus/Sjogren's autoantibody specifieites in sera with paraproteins. J. Clin. Invest. 1987; 80: 138–144
  • Tzioufas A. G., Katsikis P. D., Youinou P. Y., Moutsopoulos H. M. Sjogren's syndrome: an oligo-monoclonal B cell process. Clin. Exp. Rheumatol. 1990; 8(suppl)17–21
  • Tan E. M., Cohen A. S., Fries J. F., Masi A. T., McShane D. J., Rothfield N. F., et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1982; 25: 1271–1277
  • Arnett F. C., Edworthy S. M., Bloch D. A., McShane D. J., Fries J. F., Cooper N. S., et al. The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988; 31: 315–324
  • Homma M., Tojo T., Akizuki M. Criteria for Sjogren's syndrome in Japan. Scand. J. Rheumatol. 1986; 15(Suppl. 61)26–27
  • Ohosone Y., Akizuki M., Hirakata M., Satoh M., Yamayata H., Homma M. In vitro, production of autoantibodies to U1 ribonucleoproteins by peripheral blood mononuclear cells from patients with connective tissue diseases. Arthritis Rheum. 1986; 29: 1343–1350
  • Satoh M., Ajmani A. K., Ogasawara T., Langdon J. J., Hirakata M., Wang J., et al. Autoantibodies to RNA polymerase II are common in systemic lupus erythematosus and overlap syndrome. Specific recognition of the phosphorylated(IIO) form by a subset of human sera. J. Clin. Invest. 1994; 94: 1981–1989
  • Targoff I. N., Reichlin M. Measurement of antibody to Jo-1 by ELISA and comparison to enzyme inhibitory activity. J. Immunol. 1987; 138: 2874–2882
  • Harlow E., Lane D. Labeling antibodies. Antibodies. A laboratory manual. Cold Spring Harbor Laboratory, New York 1988; 319–358
  • Davies H. Isoelectric focusing. Isoelectric focusing, J. P. Arbuthnott, J. A. Becky. Butterworths, London 1975; 97–113
  • Akizuki M. Homogeneiety and crossreactive idiotype of autoanlibodies to SS-B antigen in connective tissue diseases. Annual Report of Study Group on the Host Factors in Intractable Diseases of Ministry of Health and Welfare. Japanese Government. 1983; 113–117
  • Satoh M., Hamilton K. J., Langdon J. J., Akizuki M., Yamagata H., Nakayama S., et al. Late development of anti-La/SS-B antibodies in a patient with Sjogren's syndrome and high titer anti-Ro/SS-A antibodies. Lupus. 1996, In press
  • Knisley K. A., Rodkey L. S. Affinity immunoblot-ting. High resolution isoelectric focusing analysis of antibody clonotype distribution. J. Immunol. Methods 1986; 95: 79–87
  • Satoh M. Studies on the immunological characteristics of autoantibodies to UIRNP. Keio Igaku. 1990; 67: 599–610
  • Reeves W. H. Use of monoclonal antibodies for the characterization of novel DNA- binding proteins recognized by human autoimmune sera. J. Exp. Mid. 1985; 161: 18–39
  • Takasaki Y., Ohgaki M., Kodama A., Ogata K., Hashimoto H., Shirai T., et al. A sandwich type enzyme-linked immunosorbent assay for proliferating cell nuclear antigen (PCNA)/cyclin using monoclonal antibodies. J. Immunol. Methods 1990; 132: 227–237
  • Satoh M., Treadwell E. L., Reeves W. H. Pristane induces high levels of anti-Su and anti-nRNP/Sm autoantibodies in BALB/c mice. Quantitation by antigen capture ELISAs based on monospecific human autoimmune sera. J. Immunol. Method 1995; 182: 51–62
  • Hardin J. A. The lupus autoantigens and the pathogenesis of systemic lupus erythematosus. Arthritis Rheum. 1986; 29: 457–460
  • Reichlin M. Significance of the Ro antigen system. J. Clin. Immunol. 1986; 6: 339–348
  • Horsfall A. C., Venables P. J. W., Mumford P. A., Maini R. N. Idiotypes on antibodies to the La (SS-B) antigen arc restricted and associated with the antigen binding site. Clin. Exp. Immunol. 1986; 63: 395–401
  • Netter H. J., Will H., Szostecki C., Guldner H. H. Repetitive P68-autoantigen specific epitopes recognized by human anti-(U1) small nuclear ribonueleoprotein autoantibodies. J. Autoimmuniry. 1991; 4: 651–663
  • Nyman U., Lundberg I., Hedfors E., Wahren M., Peterson I. IgG and IgM anti-snRNP reactivity in sequentially obtained scrum samples from patients with connective tissue discases. Ann. Rheum. Dis. 1992; 51: 1307–12
  • James J. A., Gross T., Scofield R. H., Harley J. B. Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B'-derived PPPGMRPP and PPPGIRGP induce spliceosomme autoimmunity. J. Exp. Med. 1995; 181: 453–461
  • Krduse R. M. The search for antibodies with molecular uniformity. Adv. Immunol. 1970; 12: 1–56
  • Maddison P. J., Reichlin M. Quantitation of precipitating antibodies to certain soluble nuclear antigens in SLE. Arthritis Rheum. 1977; 20: 819–824
  • Williams D. G., Brennan F. M., Stocks M. R., Maini R. N. Individual variation of anti-Sm autoantibodies in the MRL/MP-lpr/lpr mouse: age-related increase in diversity. Clin. Exp, Immunol. 1986; 65: 506–512

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.