Oligoclonality of CD8 + T cells in Multiple Sclerosis

References

• Grunewald J., Jeddi‐Tehrani M., Dersimonian H., Andersson R., Wigzell H. A persistent T cell expansion in the peripheral blood of a normal adult male: a new clinical entity?. Clin. Exp. Immunol. 1992; 89: 279–284
   PubMedGoogle Scholar
• Dersimonian H., Sugita M., Glass D. N., Maier A. L., Weinblatt M. E., Reme T., Brenner M. B. Clonal Vα 12.1 + T cell expansions in the peripheral blood of rheumatoid arthritis patients. J. Exp. Med. 1993; 177: 1623–1631
   PubMed Web of Science ®Google Scholar
• Posnett D. N., Sinha R., Kabak S., Russo C. Clonal populations of T cells in normal elderly humans: the T cell equivalent to “benign monoclonal gammapathy”. J. Exp. Med. 1994; 179: 609–618
   PubMed Web of Science ®Google Scholar
• Puisieux I., Even J., Pannetier C., Jotereau F., Favrot M., Kourilsky P. Oligoclonality of tumorinfiltrating lymphocytes from human melanomas. J. Immunol. 1994; 153: 2807–2818
   PubMed Web of Science ®Google Scholar
• Hingorani R., Choi I., Akolkar P., Gulwani B. A., Pergolizzi R., Silver J., Gregersen P. K. Clonal predominance of T Cell receptors within the CD8 + CD45RO + subset in normal human subjects. J. Immunol. 1993; 151: 5762–5769
   PubMed Web of Science ®Google Scholar
• Monteiro J., Hingorani R., Choi I. ‐H., Silver J., Pergolizzi R., Gregersen P. K. Oligoclonality in the human CD8 + T‐cell repertoire in normal subjects and monozygotic twins: implications for studies of infectious and autoimmune Diseases. Molecular Medicine. 1995; 1: 614–624
   PubMed Web of Science ®Google Scholar
• Hingorani R., Monteiro J., Furie R., Chartash E., Gregersen P. K. Oligoclonality of Vβ3 TCR chains in the CD8 + T cell population of rheumatoid arthritis patients. J. Immunol. 1996; 156: 852–858
   PubMed Web of Science ®Google Scholar
• Martin R., McFarland H. F., McFarlin D. E. Immunological aspects of demyelinating diseases. Ann. Rev. Immunol. 1992; 10: 153–187
   PubMed Web of Science ®Google Scholar
• Koh D. ‐R., Fung‐Leung W. ‐P., Ho A., Gray D., Acha‐Orbea H., Mak T. ‐W. Less mortality but more relapses in experimental allergic encephalomyelitis in CD8 ‐/‐ mice. Science 1992; 256: 1210–1213
   PubMed Web of Science ®Google Scholar
• Jiang H., Zhang S. ‐I., Pernis B. Role of CD8 + T cells in murine experimental allergic encephalomyelitis. Science 1992; 256: 1213–1215
   PubMed Web of Science ®Google Scholar
• Gaur A., Wiers B., Liu A., Rothbard J., Fathman C. G. Amelioration of autoimmune encephalomyelitis by myelin basic protein synthetic peptide induced anergy. Science 1992; 258: 1491–1494
   PubMed Web of Science ®Google Scholar
• Zhang J., Medaer R., Stinissen P., Hafler D., Raus J. MHC‐restricted depletion of human myelin basic protein‐reactive T cells by T cell vaccination. Science 1993; 261: 1451–1454
   PubMed Web of Science ®Google Scholar
• Wei S., Charmley P., Robinson M. A., Concannon P. The extent of the human germline T‐cell receptor V beta gene segment repertoire. Immunogenetics. 1994; 40: 27–36
   PubMedGoogle Scholar
• Oksenberg J. R., Panzara M. A., Begovich A. B., Mitchell D., Erlich H. A., Murray R. S., Shimonkevitz R., Sherritt M., Rothbard J., Bernard C. C. A., Steinman L. Selection for T‐cell receptor Vβ‐Dβ‐Jβ gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis. Nature 1993; 362: 68–70
   PubMed Web of Science ®Google Scholar
• Allegretta M., Albertini R. J., Howell M. D., Smith L. R., Martin R., McFarland H. F., Sriram S., Brostoff S., Steinman L. Homologies between T cell receptor junctional sequences unique to multiple sclerosis and T cells mediating experimental allergic encephalitis. J. Clin. Invest. 1994; 94: 105–109
   PubMed Web of Science ®Google Scholar
• Gold D. P., Vainiene M., Celnik B., Wiley S., Gibbs C., Hashim G. A., Vandenbark A. A., Offner H. Characterization of the immune response to a secondary encephalitogenic epitope of basic protein in Lewis rat. J. Immunol. 1992; 148: 1712–1717
   PubMed Web of Science ®Google Scholar
• Chou Y. K., Henderikx P., Vainiene M., Whitham R., Bourdette D., Chou C. H.‐J., Hashim G., Offner H., Vandenbark A. A. Specificity of human T cell clones reactive to immunodominant epitopes of myelin basic protein. J. Neurosci. Res. 1991; 28: 280–290
   PubMed Web of Science ®Google Scholar
• Kotzin B. L., Karuturi S., Chou Y. K., Lafferty J., Forrester J. M., Better M., Nedwin G. E., Offner H., Vandenbark A. A. Preferential T‐cell receptor β‐chain variable gene use in myelin basic protein‐reactive T cell clones from patients with multiple sclerosis. Proc. Natl Acad. Sci. USA. 1991; 88: 9161–9165
   PubMed Web of Science ®Google Scholar
• Zhang J. W., Medaer R., Chin Y., van den Berg‐Loonen E., Raus J. C. M. Myelin basic protein‐specific T lymphocytes in multiple sclerosis and controls: precursor frequency, fine specificity, and cytotoxicity. Ann. Neurol. 1992; 32: 330–338
   PubMed Web of Science ®Google Scholar
• Ota K., Matsui M., Milford E. L., Mackin G. A., Weiner H. I., Hafler D. A. T cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 1990; 346: 183–187
   PubMed Web of Science ®Google Scholar
• Gaur A., Ruberti G., Haspel R., Mayer J. P., Fathman C. G. Requirement for CD8 + cells in T cell receptor peptide‐induced clonal unresponsiveness. Science 1993; 258: 91–94
   Google Scholar
• Monteiro J., Hingorani R., Pergolizzi R., Apatoff B., Gregersen P. K. Clonal dominance of CD8 + T cells in multiple sclerosis (MS). The FASEB Journal Abstracts. 1994; 8: A204
   Google Scholar
• Morley J., Batliwalla F., Hingorani R., Gregersen P. K. Oligoclonal CD8 + T cells are preferentially expanded in the CD57 + subset. J. Immunol. 1995; 154: 6182–6190
   PubMed Web of Science ®Google Scholar
• Loughran T. P., Jr. Clonal diseases of large granular lymphocytes. Blood. 1993; 82: 1–14
   PubMed Web of Science ®Google Scholar
• Behar S., Roy C., Brenner M. B. Autoreactive Vα12 CD8 T cells are clonally expanded in rheumatoid arthritis. Arthritis and Rheumatism. 1994; 37: S313, (abstract)
   Google Scholar
• Ware R., Jiang H., Braunstein N., Kent J., Wiener E., Pernis B., Chess L. Human CD8 + T lymphocyte clones specific for T cell receptor V beta families expressed on autologous CD4 + T cells. Immunity. 1995; 2: 177–184
   PubMed Web of Science ®Google Scholar
• Jiang H., Ware R., Stall A., Flaherty L., Chess L., Pernis B. Murine CD8 + T cells that specifically delete autologous CD4 + T cells expressing V beta 8 TCR: a role of the Qa‐1 molecule. Immunity. 1995; 2: 185–194
   PubMed Web of Science ®Google Scholar
• Bourdette D. N., Whitham R. H., Chou Y. K., Morrison W. J., Atherton J., Kenny C., Liefeld D., Hashim G. A., Offner H., Vandenbark A. A. Immunity to TCR peptides in multiple sclerosis. I. Successful immunization of patients with synthetic V Beta 5.2 and V Beta 6.1 CDR2 peptides. J. Immunol. 1994; 152: 2510–2519
   PubMed Web of Science ®Google Scholar
• Chou Y. K., Morrison W. J., Weinberg A. D., Dedrick Whitham R., Bourdette D. N., Hashim G., Offner H., Vandenbark A. A. Immunity to TCR peptides in multiple sclerosis. II. T cell recognition of V beta 5.2 and V beta 6.1 CDR2 peptides. J. Immunol. 1994; 152: 2520–2529
   PubMed Web of Science ®Google Scholar