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Autoimmunity Volume 26, 1997 - Issue 3
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Original Article

Anti-NGF Autoantibodies and NGF in Sera of Alzheimer Patients and in Normal Subjects in Relation to Age

Eleni Dlcou INSERM U298, Centre Hospitalier Régional, Angers; Department of Cell Biology, Georgetown University Medical Center, Washington, DC, USA; Service de Neurologie, Centre Hospitalier Régional, Angers
,
Patrick Vermersch INSERM U422, Lille, France
,
Isabelle Penisson-Besnier Service de Neurologie, Centre Hospitalier Régional, Angers
,
Frederic Dubas Service de Neurologie, Centre Hospitalier Régional, Angers
&
Veronique Nerriere INSERM U298, Centre Hospitalier Régional, Angers
Pages 189-194 | Received 03 Feb 1997, Accepted 23 Apr 1997, Published online: 07 Jul 2009

References

  • Whitehouse P. J., Price D. L., Struble R. G., Clark A. W., Coyle J. T., De Long M. R. Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. Science 1982; 215: 1237–1239
  • Thoenen H. The changing scene of neurotrophic factors. Trends Neurosci 1991; 14: 165–170
  • McGeer P. L., McGeer E., Rogers J., Sibley J. Anti-inflammatory drugs and Alzheimer disease. Lancet 1990; 335: 1037
  • Schnabel J. New Alzheimer's therapy suggested. Science 1993; 260: 1719–1720
  • Dicou E., Hurez D., Nerriere V. Natural autoantibodies against the nerve growth factor in autoimmune diseases. J. Neuroimmunol 1993; 477: 159–168
  • Dicou E., Perrot S., Menkes C. J., Masson C., Nerriere V. Nerve growth factor (NGF) autoantibodies and NGF in the synovial fluid: implications in spondylarthropathies. Autoimmunity 1996; 24: 1–9
  • Aloe L., Skaper S. D., Leon A., Levi-Montalcini R. Nerve growth factor and autoimmune diseases. Autoimmunity 1994; 19: 141–158
  • Dicou E., Nerriere V., Naud M. C., deKozak Y. NGF involvement in ocular inflammation: secretion by rat resident cells. NeuroReport 1994; 6: 26–28
  • Dicou E., Masson C., Jabbour W., Nerriere V. Increased frequency of NGF in sera of rheumatoid arthritis and systemic lupus erythematosus patients. NeuroReport 1993; 5: 321–324
  • McKahnn G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E. M. Clinical diagnosis of Alzheimer disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer Disease. Neurology 1984; 34: 939–944
  • Mobley W. C, Schenker A., Shooter E. M. Characterization and isolation of proteolytically modified nerve growth factor. Biochem. 1976; 15: 5543–5551
  • Heinrich G., Meyer T. E. Nerve growth factor (NGF) is present in human placenta and semen, but undetectable in normal and Paget's disease blood: measurements with an anti-mouse-NGF enzyme immunoassay using a recombinant human NGF reference. Biochem. Bioplns. Res. Commun. 1988; 155: 482–486
  • Murase K., Nabeshima T., Robitaille Y., Quirion R., Ogawa M., Hayashi K. NGF level is not decreased in the serum, brain-spinal fluid, hippocampus, or parietal cortex of individuals with Alzheimer's disease. Biochem. Biophys. Res. Commun. 1993; 193: 198–203
  • Massaro A. R., Soranzo C., Bigon E., Battiston S., Morandi A., Carnevale A., Callegaro L. Nerve growth factor (NGF) in cerebrospinal fluid (CSF) from patients with various neurological disorders. Ital. J. Neurol. Set. 1994; 15: 105–108
  • Goedert M., Fine A., Hunt S. P., Ullrich A. Nerve growth factor mRNA in peripheral and central rat tissues and in the human brain: normal levels in basal forebrain in Alzheimer's disease. Mol. Bruin Res. 1986; 1: 85–92
  • Ernfors P., Lindefors N., Chan-Palay V., Persson H. Cholinergic neurons of the nucleus basalis express elevated levels of nerve growth factor receptor mRNA in senile dementia of the Alzheimer type. Dementia 1990; 1: 138–145
  • Goedert M., Fine A., Dawbarn D., Wilcock G. K., Chao M. V. Nerve growth factor receptor mRNA distribution in human brain: normal levels in basal forebrain in Alzheimer's disease. Mol. Brain Res. 1989; 5: 1–7
  • Higgins G. A., Mufson E. J. NGF receptor gene expression is decreased in the nucleus basalis in Alzheimer's disease. Exp. Neurol. 1989; 106: 222–236
  • Allen S. J., MacGowan S. H., Treanor J. J. S., Feeney R., Wilcock G. K., Dawbarn D. Normal β-NGF content in Alzheimer's disease cerebral cortex and hippocampus. Neurosci. Lett. 1991; 131: 135–139
  • Scott S. A., Mufson E. J., Weingartner J. A., Skau K. A., Crutcher K. A. Nerve growth factor in Alzheimer's disease: Increased levels throughout the brain coupled with declines in nucleus basalis. J. Neurosci. 1995; 15: 6213–6221
  • Olson L. NGF and the treatment of Alzheimer's disease. Exper. Neurol. 1993; 124: 5–15
  • Weksler M. E., Schwab R. The immunogenet-ics of immune senescence. Exper. Clin. Immunogenetics 1992; 9: 182–187
  • Dicou E., Nerriere V. Evidence that natural autoantibodies against the nerve growth factor (NGF) may be potential carriers of NGF. J. Neuroimmunoi. 1997; 75: 200–203

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