Immunogenetics and the Cause of Autoimmune Disease

References

• Baker D., Rosenwasser 0. A., O'Neill J. K., Turk J. L. “Genetic analysis of experimental allergic enceph-alo myelitis in mice”. J Immunol 1995; 155: 4046–4051
   PubMed Web of Science ®Google Scholar
• Barnett A. H., Eff C, Leslie R. D. G., Pyke D. A. “Diabetes in identical twins”. Diabetologia 1981; 20: 87–93
   PubMed Web of Science ®Google Scholar
• Baxter A. G., Cooke A. “The genetics of the NOD mouse”. Diabetes Metabolism Reviews 1995; 11: 315–335
   PubMedGoogle Scholar
• Baxter A. G., Mandel T. E. “Hemolytic anaemia in nonobese diabetic mice”. European J Immunol 1991; 21: 2051–2055
   PubMed Web of Science ®Google Scholar
• Bell G. I., Horita S., Karam J. H. “A polymorphic locus near the human insulin gene is associated with insulin dependent diabetes mellitus”. Diabetes 1984; 33: 176–183
   PubMed Web of Science ®Google Scholar
• Boitard C. “Insulitis and autoreactive T cells”. presented at, Lessons from animal diabetes, Orvieto, Italy. 1995
   Google Scholar
• Copeman J. B., Cucca F., Hearne C. M., Cornall R. J., Reed P. W., Ronningen K. S., Undlien D. E., Nistico L., Buzzetti R, Tosi R., Pociot F., Nerup J., Cornelis F., Barnett A. H., Bain S. C., Todd J. A. “Linkage disequilibrium mapping of a type 1 diabetes susceptibility gene (IDDM7) to chromosome 2q31-q33”. Nature Genetics 1995; 9: 80–85
   PubMedGoogle Scholar
• Cornall R. J., Prins J. B., Todd J. A., Pressey A., DeLarato N. H., Wicker L. S., Peterson L. B. “Type 1 diabetes in mice is linked to the interleukin-1 receptor and Lsh/Ity/Bcg genes on chromosome 1”. Nature 1991; 353: 262–265
   PubMed Web of Science ®Google Scholar
• Davies J. L., Kawaguchi Y., Bennett S. T., Copeman J. B., Cordell H. J., Pritchard L. E., Reed P. W., Gough S. C. L., Jenkins S. C, Palmer S. M., Balfour K. M., Rowe B. R., Farrall M., Barnett A. H., Bain S. C., Todd T. A. “A genome wide search for human type 1 diabetes susceptibility genes”. Nature 1994; 371: 130–136
   PubMed Web of Science ®Google Scholar
• De Gouyon B., Melanitou E., Richard M. F., Requarth M., Hahn I. H., Guenet J. L., Demenais F., Julier C, Lathrop G. M., Boitard C., Avner P. “Genetic analysis of diabetes and insulitis in an interspecific cross of the nonobese diabetic mouse with Mus spretus”. Proc Natl Acad Sci, USA 1993; 90: 1877–1881
   PubMed Web of Science ®Google Scholar
• Degnbol B., Green A. “Diabetes mellitus among first-and second-degree relatives of early onset diabetics”. Ann Hum Genet Lond 1978; 42: 25–47
   PubMed Web of Science ®Google Scholar
• Deschamps I., Lastradet H., Bonaiti C, Schmid M., Bus-Son M., Benajam A., Marcelli-Barge A., Hors J. “HLA Genotype studies in juvenile insulin-dependent diabetes”. Diabetologia 1980; 19: 189–193
   PubMed Web of Science ®Google Scholar
• Diabetes Epidemiology Research International Group. “Geographic patterns of childhood insulin-dependent diabetes mellitus”. Diabetes 1988; 37: 1113–1119
   PubMed Web of Science ®Google Scholar
• Falconer D. S. “The inheritance of liability to certain diseases, estimated from the incidence among relatives”. Ann Hum Genet Lond 1965; 29: 51–76
   Web of Science ®Google Scholar
• Falconer D. S. “The inheritance of liability'to diseases with variable age of onset, with particular reference to diabetes mellitus”. Ann Hum Genet Lond 1967; 31: 1–20
   PubMed Web of Science ®Google Scholar
• Falconer D. S. Introduction to quantitative genetics3rd Edn. Longman Scientific, HarlowUK 1989
   Google Scholar
• Field L. L., Tobias R., Magnus T. “A locus on chromosome 15q26 (IDDM3) produces susceptibility to insulin-dependent diabetes mellitus”. Nature Genetics 1994; 8: 189–194
   PubMedGoogle Scholar
• Frankel W. N. “Taking stock of complex trait genetics in mice”. Trends in Genetics 1995; 11: 471–477
   PubMed Web of Science ®Google Scholar
• Galton F. Natural Inheritance 1989
   Google Scholar
• Garchon H. J., Bedossa P., Eloy L., Bach J. F. “Identification and mapping to chromosome 1 of a susceptibility locus for periinsulitis in non-obese diabetic mice”. Nature 1991; 353: 260–2
   PubMedGoogle Scholar
• Ghosh S., Palmer S. M., Rodrigues N. R., Corsell H. J., Hearne C. M., Cormall R. J., Prins J. B., McShane P., Lathrop G. M., Peterson L. B., Wicker L. S., Todd J. A. “Polygenic control of autoimmune diabetes in nonobese diabetic mice”. Nature Genetics 1993; 4: 404–409
   PubMed Web of Science ®Google Scholar
• Goillot A., Mutin M., Touraine J. L. “Sialadenitis in nonobese diabetic mice: Transfer into syngeneic healthy neonates by splenic T lymphocytes”. Clinical Immunology and Immunopathology 1991; 59: 462–473
   PubMedGoogle Scholar
• Goldstein D. E., Drash A., Gibbs J., Blizzard R. M. “Diabetes mellitus: the incidence of circulating antibodies against thyroid, gastric and adrenal tissue”. J Pediatrics 1970; 77: 304–306
   PubMed Web of Science ®Google Scholar
• Grennan D. M., Sanders P. A., Thomson W., Dyer P. A. “Rheumatoid arthritis: inheritance and association with other autoimmune disease”. Disease Markers 1986; 4: 157–62
   Google Scholar
• Haldane J. B. S. “The biology of inequality”. Heredity and Politics. Allen and Unwin, London 1938
   Google Scholar
• Hashimoto L., Habita C, Beressi J. P., Delepine M., Besse C, Cambon-Thomsen A., Deschamps I., Rotter J. I., Djoulah S., James M. R., Froguel P., Weissenbach J., Lathrop G. M., Julier C. “Genetic mapping of a susceptibility locus for insulin dependent diabetes mellitus on chromosome 1 lq”. Nature 1994; 371: 161–164
   PubMed Web of Science ®Google Scholar
• Hattori M., Buss J. B., Jackson R. A., Glimcher L., Dorf M. E., Minami M., Makino S., Moriwaki K., Kuzuya H., Imura H., Strauss W. M., Seidman J. G., Eisenbarth G. S. “The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex”. Science 1986; 231: 733–735
   PubMed Web of Science ®Google Scholar
• Humphreys-Beher M. G., Brinkley L., Purushotham K. R., Wang P. L., Nakagawa Y., Dusek D., Kerr M., Che K., Chan E. K. L. “Characterisation of antinuclear autoantibodies present in the serum from nonobese diabetic mice”. Clinical Immunology and Immunopathology 1993; 68: 350–356
   PubMedGoogle Scholar
• Ikegami H., Makino S., Yamato E., Kawaguchi Y., Ueda H., Sakamoto T., Takekawa K., Ogihara T. “Identification of a new susceptibility locus for insulin dependent diabetes mellitus by ancestral haplotype con-genic mapping”. J Clin Invest 1995; 96: 1936–1942
   PubMed Web of Science ®Google Scholar
• Julier C, Hyer R. N., Davies J., Merlin F., Soularue P., Briant L., Cathelineau G., Deschamps I., Rotter J. I., Froguel P., Boitard C, Bell J. I., Lathrop G. M. “Insulin-IGF2 region on chromosome 1 lp encodes a gene implicated in HLA-DR4-dependent diabetes susceptibility”. Nature 1991; 354: 155–159
   PubMedGoogle Scholar
• Kaprio J., Tuomilehto J., Koskenvuo M., Romanov K., Reunanen A., Eriksson J., Stengard J., Kesanie Y. A. “Concordance for type 1 (insulin-dependent) and type 2 (noninsulin-dependent) diabetes mellitus in a population-based cohort of twins in Finland”. Diabetologia 1992; 35: 1060–1067
   PubMed Web of Science ®Google Scholar
• Kono D. H., Burlingame R. W., Owens D. G., Kuramochi A., Balderas R. S., Balomenos D., Theofilopolous A. N. “Lupus susceptibility loci in New Zealand mice”. Proc Natl Acad Sci, USA 1994; 91: 10168–10172
   PubMed Web of Science ®Google Scholar
• Kumar D., Gemayel N. S., Deapen D., Kapadia D., Yama Lee M., Dwyer J. H., Roy-Burman P., Bray G. A., Mack T. M. “North American twins with IDDM”. Diabetes 1993; 42: 1351–1363
   PubMed Web of Science ®Google Scholar
• Kyvik K. O., Green A., Beck-Nielsen H. “Concordance rates of insulin dependent diabetes mellitus: a population based study of young Danish twins”. Brit Med J 1995; 311: 913–917
   PubMed Web of Science ®Google Scholar
• Kyvik K. O., Green A., Beck-Nielsen H. “Concordance rates of insulin dependent diabetes mellitus: a population based study of young Danish twins”. Brit Med J 1995; 311: 913–917
   PubMed Web of Science ®Google Scholar
• Little C. C. “A possible Mendelian explanation for a type of inheritance apparently non-Mendelian in nature”. Science 1914; 40: 904–906
   Google Scholar
• Lorenzen T., Pociot F., Hougaard P., Nerup J. “Long-term risk of IDDM in first degree relatives of patients with IDDM”. Diabetologia 1994; 37: 321–327
   PubMed Web of Science ®Google Scholar
• McAleer M. A., Reifsnyder P., Palmer S. M., Prochazka M., Love J. M., Copeman J. B., Powell E. E., Rodrigues N. R., Prins J. B., Serreze D. V. “Crosses of NOD mice with the related NON strain: a polygenic model for IDDM”. Diabetes 1995; 44: 1186–1195
   PubMed Web of Science ®Google Scholar
• Meeker N. D., Hickey W. F., Korngold R., Hansen W. K., Sudweeks J. D., Wardell B. B., Griffith J. S., Teu K. “Multiple loci govern the bone marrow-derived immunoregulatory mechanism controlling dominant resistance to autoimmune orchitis”. Proc Natl Acad Sci, USA 1995; 92: 5684–5688
   PubMedGoogle Scholar
• Morahan G., Huang D., Tait B. D., Colman P. G., Harrison L. C. “Markers on distal chromosome 2q linked to insulin-dependent diabetes mellitus”. Science 1996; 272: 1811–1813
   PubMedGoogle Scholar
• Morahan G., McClive P., Huang D., Little P., Baxter A. G. “Genetic and physiological association of diabetes susceptibility with raised Na + /H + exchange activity”. Proc Natl Acad Sci, USA 1994; 91: 5898–5902
   PubMed Web of Science ®Google Scholar
• Morel L., Rudofsky U. H., Longmate J. A., Schiffenbauer J., Wakeland E. K. “Polygenic control of susceptibility to murine systemic lupus erythematosus”. Immunity 1994; 1: 219–229
   PubMed Web of Science ®Google Scholar
• Olmos P., A'Hern R., Millward B. A., Risley D., Pyke D. A., Leslie R. D. G. “The significance of the concordance rate for type 1 (insulin dependent) diabetes in identical twins”. Diabetologia 1988; 31: 747–750
   PubMed Web of Science ®Google Scholar
• Owerbach D., Gabbay K. H. “The HOXD8 locus (2q31) is linked to type 1 diabetes”. Diabetes 1995; 44: 132–136
   PubMedGoogle Scholar
• Palmer J. P., McCulloch D. K. “Prediction and prevention of IDDM-1991”. Diabetes 1991; 40: 943–947
   PubMed Web of Science ®Google Scholar
• Prins J. B., Todd J. A., Rodrigues N. R., Ghosh S., Hogarth P. M., Wicker L. S., Gaffney E. G., Podolin P. L., Fischer P. A., Sirotina A., Peterson L. B. “Linkage on chromosome 3 of autoimmune diabetes and defective Fc receptor for IgG in NOD mice”. Science 1993; 260: 695–698
   PubMed Web of Science ®Google Scholar
• Rich S. S. “Mapping genes in diabetes”. Diabetes 1990; 39: 1315–1319
   PubMed Web of Science ®Google Scholar
• Risch N, Ghosh S., Todd J. A. “Statistical evaluation of multiple locus linkage data in experimental species and its relevance to human studies”. Am J Hum Genet 1993; 53: 702–714
   PubMed Web of Science ®Google Scholar
• Rodrigues N. R., Cornall R. J., Chandler P., Simpson E., Wicker L. S., Peterson L. B., Todd J. A. “Mapping of an insulin-dependent diabetes locus Idd9 in NOD mice to chromosome 4”. Mammalian Genome 1994; 5: 167–170
   PubMed Web of Science ®Google Scholar
• Ronningen K. S., Gjertsen H. A., Iwe T., Spurkland A., Hansen T., Thorsby E. “Particular HLA-DQ a/b heterodimer associated with IDDM susceptibility in both DR4-DQw4 Japanese and DR4-DQw8/DRw8-DQw4 whites”. Diabetes 1991; 40: 759–763
   PubMedGoogle Scholar
• Rowe R. E., Wapelhorst B., Bell G. I., Risch N., Spielman R. S., Concannon P. “Linkage and association between insulin dependent diabetes mellitus susceptibility and markers near the glucokinase gene on chromosome 7”. Nature Genetics 1995; 10: 240–242
   PubMedGoogle Scholar
• Sheehy M. J. “HLA and insulin dependent diabetes”. Diabetes 1992; 41: 123–129
   PubMed Web of Science ®Google Scholar
• Shimada A., Charlton B., Taylor-Edwards C., Fathman C. G. “Beta cell destruction may be a late consequence of the autoimmune process in non-obese diabetic mice”. Diabetes 1996; 45: 1063–1067
   PubMed Web of Science ®Google Scholar
• Sundvall M., Jirholt J., Yang H. T., Jansson L., Engstrom A., Pettersson U., Holmdahl R. “Identification of murine loci associated with susceptibility to chronic experimental autoimmune encephalomyelitis”. Nature Genetics 1995; 10: 313–317
   PubMed Web of Science ®Google Scholar
• Teuscher C, Wardell B. B., Lunceford J. K., Michael S. D., Tung K. S. K. “Aod2, the locus controlling development of atrophy in neonatal thymectomy-induced autoimmune ovarian dygenesis, co-localises with 112, Fgfb and Idd3”. J Exp Med 1996; 183: 631–637
   Google Scholar
• Thomsen M., Platz P., Ortved A. O., Christy M., Lyngsoe J., Nerup J., Rasmussen K., Ryder L. P., Staub-Nielsen L., Svejgaard A. “MLC typing in juvenile diabetes mellitus and idiopathic Addison's disease”. Transplant Rev 1975; 22: 125–146
   PubMedGoogle Scholar
• Tillil H., Kobberling J. “Age-corrected empirical genetic risk estimates for first-degree relatives of IDDM patients”. Diabetes 1987; 36: 93–99
   PubMed Web of Science ®Google Scholar
• Todd J. A., Aitman T. J., Cornall R. J., Ghosh S., Hall J. R. S., Hearne C. M., Knight A. M., Love J. M., McAleer M. A., Prins J. B., Rodrigues N., Lathrop M., Pressey A., De-Larato N. H., Peterson L. B., Wicker L. S. “Genetic analysis of autoimmune type 1 diabetes mellitus in mice”. Nature 1991; 351: 542–547
   PubMed Web of Science ®Google Scholar
• Todd J. A., Bell J. I., McDevitt H. O. “HLA-DQb gene contributes to susceptibility and resistance to insulin-dependent diabetes mellitus”. Nature 1987; 329: 599–604
   PubMed Web of Science ®Google Scholar
• Todd J. A. “Genetic analysis of type 1 diabetes using whole genome approaches”. Proc Natl Acad Sci, USA 1995; 92: 8560–8565
   PubMedGoogle Scholar
• Vyse T. J., Todd J. A. “Genetic analysis of autoimmune disease”. Cell 1996; 85: 311–318
   PubMed Web of Science ®Google Scholar
• Wicker L. S., Appel M. C, Dotta F., Pressey A., Miller B. J., Delarato N. H., Fischer P. A., Boltz R. C., Peterson L. B. “Autoimmune syndromes in major histocompatibility complex (MHC) congenic strains of nonobese diabetic (NOD) mice. The MHC is dominant for insulitis and cyclophosphamide-induced diabetes”. J. Exp Med 1992; 176: 67–77
   PubMed Web of Science ®Google Scholar
• Wicker L. S., Miller B. J., Coker L. Z., McNally S. E., Scott S., Mullen Y., Appel M. C. “Genetic control of diabetes and insulitis in the nonobese diabetic (NOD) mouse”. J Exp Med 1987; 165: 1639–1654
   PubMed Web of Science ®Google Scholar
• Wicker L. S., Miller B. J., Fischer P. A., Pressey A., Peterson L. B. “Genetic control of diabetes and insulitis in the nonobese diabetic mouse-Pedigree analysis of a diabetic H-2nod/b heterozygote”. J Immunol 1989; 142: 781–784
   Google Scholar
• Wicker L. S., Todd J. A., Prins J. B., Podolin P. L., Renjilian R. J., Peterson L. B. “Resistance alleles at two non-major histocompatibility complex-linked insulin dependent diabetes loci on chromosome 3, Idd3 and IddlO, protect nonobese diabetic mice from diabetes”. J Exp Med 1994; 180: 1705–1713
   PubMed Web of Science ®Google Scholar
• Wicker L. S., Todd J. A., Peterson L. B. “Genetic control of autoimmune diabetes in the NOD mouse”. Annu Rev Immunol 1995; 13: 179–200
   PubMed Web of Science ®Google Scholar
• Zamil S. S., Al-Sabbagh A., Nelson P. A., Kaul D., St Charles M., Mitchell D. J., Steinman L., Winer H. L., Kuchroo V. K. “Lupus prone mice are susceptible to organ specific autoimmune disease experimental allergic encephalomyelitis”. Pathobiology 1994; 62: 113–119
   Google Scholar