Heat Shock Proteins and Arthritis – New Readers Start Here

References

• van Eden W., Thole J., van der Zee R., Noordzij A., van Embden J., Hensen E. Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis. Nature 1988; 331: 171–3
   PubMed Web of Science ®Google Scholar
• Craig E. A., Weissman J. S., Horwich A L. Heat shock proteins and molecular chaperones: Mediators of protein conformation and turnover in the cell. Cell 1994; 78: 365–372
   PubMed Web of Science ®Google Scholar
• Kaufmann S. Heat shock proteins and pathogenesis of bacterial infections. Springer Semin Immunopathol 1991; 13: 25–36
   PubMedGoogle Scholar
• Young D. Heat shock proteins: immunity and autoimmunity. Curr Opin Immunol 1992; 4: 396–400
   PubMed Web of Science ®Google Scholar
• Winfield J., Jarjour W. Stress proteins, autoimmunity, and autoimmune disease. Curr Top Microbiol Immunol 1991; 167: 161–89
   PubMed Web of Science ®Google Scholar
• Cohen I., Young D. Autoimmunity, microbial immunity and the immunological homunculus. Immunol Today 1991; 12: 105–10
   PubMedGoogle Scholar
• Cohen I. R. Autoimmunity to chaperonins in the pathogenesis of arthritis and diabetes. Annu Rev Immunol 1991; 9: 567–89
   PubMed Web of Science ®Google Scholar
• van Eden W., Hogervorst E., Hensen E., van der Zee R., van Embden J., Cohen 1. A cartilage mimicking T cell epitope on a 65K mycobacterial heat shock protein: adjuvant arthritis as a model for human rheumatoid arthritis. Curr Top Microbiol Immunol 1989; 145: 27–43
   PubMedGoogle Scholar
• Hogervorst E. J., Schouls L., Wagenaar J P., Boog C. J., Spaan W. J., van Embden J. D. Modulation of experimental autoimmunity: treatment of adjuvant arthritis by immunization with a recombinant vaccinia virus. Infect Immun 1991; 59: 2029–35
   PubMed Web of Science ®Google Scholar
• Lopez-Guerrero J. A., Lopez-Bote J. P., Ortiz M. A., Gupta R. S., Paez E., Bernabeu C. Modulation of adjuvant arthritis in Lewis rats by recombinant vaccinia virus expressing the human 60-kilodalton heat shock protein. Infect Immun 1993; 61: 4225–31
   PubMed Web of Science ®Google Scholar
• Yang X., Gasser J., Feige U. Prevention of adjuvant arthritis in rats by a nonapeptide from the 65 kD mycobacterial heat shock protein. Clin Exp Immunol 1990; 81: 189–94
   PubMedGoogle Scholar
• Ragno S., Colston M., Lowrie D., Winrow V., Blake D., Tascon R. Protection of rats from adjuvant arthritis by immunization with naked DNA encoding for mycobacterial heat shock protein 65. Arthritis Rheum 1997; 40
   PubMedGoogle Scholar
• Lopez-Guerrero J. A., Ortiz M. A., Paez E., Bernabeu C., Lopez-Bote J. P. Therapeutic effect of recombinant vaccinia virus expressing the 60-kd heat-shock protein on adjuvant arthritis. Arthritis Rheum 1994; 37: 1462–1467
   PubMed Web of Science ®Google Scholar
• van den Broek M., Hogervorst E., van Bruggen M., van Eden W., van der Zee W., van den Berg W. Protection against streptococcal cell wall induced arthritis by pretreatment with the 65 kD mycobacterial heat shock protein. J Exp Med 1989; 170: 449–66
   PubMed Web of Science ®Google Scholar
• Gripenberg-Lerche C, Toivanen A., Toivanen P. Yersinia-associated arthritis in rats: Effect of 65 kDa heat shock protein, bovine serum albumin and incomplete Freund's adjuvant. Clin Exp Rheumatol 1995; 13: 321–325
   PubMedGoogle Scholar
• Thompson S. J., Butcher P. D., Patel V. K., Rook G. A., Stanford J., van der Zee R. Modulation of pristane-induced arthritis by mycobacterial antigens. Autoimmunity 1991; 11: 35–43
   PubMed Web of Science ®Google Scholar
• Lorentzen J. C, Erlandsson H., Mussener A., Matts-Son L., Kleinau S., Nyman U. Specific and long-lasting protection from collagen-induced arthritis and oil-induced arthritis in DA rats by administration of immunogens. Scand J Immunol 1995; 42: 82–9
   PubMedGoogle Scholar
• Billingham M. E., Carney S., Butler R., Colston M. J. A mycobacterial 65-kD heat shock protein induces antigen-specific suppression of adjuvant arthritis, but is not itself arthritogenic. J Exp Med 1990; 171: 339–44
   PubMed Web of Science ®Google Scholar
• Kingston A. E., Hicks C. A., Colston M. J., Billingham M. E. A 71-kD heat shock protein (hsp) from Mycobacterium tuberculosis has modulatory effects on experimental rat arthritis. Clin Exp Immunol 1996; 103: 77–82
   PubMed Web of Science ®Google Scholar
• Anderton S. M., van der Zee R., Noordzij A., van Eden W. Differential mycobacterial 65-kDa heat shock protein T cell epitope recognition after adjuvant arthritis-inducing or protective immunization protocols. J Immunol 1994; 152: 3656–3664
   PubMed Web of Science ®Google Scholar
• Anderton S. M., van der Zee R., Prakken B., Noordzij A., van Eden W. Activation of T cells recognizing self 60-kD heat shock protein can protect against experimental arthritis. J Exp Med 1995; 181: 943–952
   PubMed Web of Science ®Google Scholar
• Nicholson L., Kuchroo V. Manipulation of the Thl/Th2 balance in autoimmune disease. Curr Opin Immunol 1996; 8: 837–842
   PubMed Web of Science ®Google Scholar
• Chaturvedi P., Yu Q., Southwood S., Sette A., Singh B. Peptide analogs with different affinities for MHC alter the cytokine profile of T helper cells. Int Immunol 1996; 8: 745–755
   PubMed Web of Science ®Google Scholar
• Kleinau S., Soderstrom K., Kiessling R., Klareskog L. A monoclonal antibody to the mycobacterial 65 kDa heat shock protein (ML 30) binds to cells in normal and arthritic joints of rats. Scand J Immunol 1991; 33: 195–202
   PubMedGoogle Scholar
• De Graeff Meeder E., Voorhorst M., van Eden W., Schu-Urman H., Huber J., Barkley D. Antibodies to the mycobacterial 65 kd heat shock protein are reactive with synovial tissue of adjuvant arthritic rats and patients with rheumatoid arthritis and osteoarthritis. Am J Pathol 1990; 137: 1013–7
   PubMedGoogle Scholar
• Barker R. N., Wells A. D., Ghoraishian M., Easterfield A. J., Hitsumoto Y., Elson C. J. Expression of mammalian 60-kD heat shock protein in the joints of mice with pristane-induced arthritis. Clin Exp Immunol 1996; 103: 83–8
   PubMedGoogle Scholar
• Birk O. S., Elias D., Weiss A. S., Rosen A., van der Zee R., Walker M. D. NOD mouse diabetes: The ubiquitous mouse Hsp60 is a beta-cell target antigen of autoimmune T cells. J Autoimmun 1996; 9: 159–166
   PubMedGoogle Scholar
• Elias D., Markovits D., Reshef T., van der Zee R., Cohen I. Induction and therapy of autoimmune diabetes in the non obese diabetic (NOD/Lt) mouse by a 65 kDa heat shock protein. Proc Natl Acad Sci (USA) 1990; 87: 1576–80
   PubMed Web of Science ®Google Scholar
• Elias D., Cohen I. R. Treatment of autoimmune diabetes and insulitis in NOD mice with heat shock protein 60 peptide p277. Diabetes 1995; 44: 1132–1138
   PubMed Web of Science ®Google Scholar
• Elias D., Cohen I. R. The hsp60 peptide p277 arrests the autoimmune diabetes induced by the toxin Strep-tozotocin. Diabetes 1996; 45: 1168–1172
   PubMed Web of Science ®Google Scholar
• Thompson S., Rook G., Brealey R., van der Zee R., Elson C. Autoimmune reactions to heat shock proteins in pristane induced arthritis. Eur J Immunol 1990; 20: 2479–84
   PubMed Web of Science ®Google Scholar
• Thompson S. J., Elson C. J. Susceptibility to pristane-induced arthritis is altered with changes in bowel flora. Immunol Lett 1993; 36: 227–31
   PubMedGoogle Scholar
• Bjork J., Kleinau S., Midtvedt T., Klareskog L., Smedegard G. Role of the bowel flora for development of immunity to hsp 65 and arthritis in three experimental models. Scand J Immunol 1994; 40: 648–652
   Google Scholar
• Anderton S. M., van der Zee R., Goodacre J. A. Inflammation activates self hsp60-specific T cells. Eur J Immunol 1993; 23: 33–38
   PubMedGoogle Scholar
• Goodall J. C, Henwood J., Bacon P. A., Gaston J. S. H. Marked conservation of complementarity-determining region 3 of the beta-chain of TCRs recognizing a mycobacterial heat shock protein 60-derived peptide with strong sequence similarity to human heat shock protein 60. J Immunol 1995; 155: 2329–2338
   PubMedGoogle Scholar
• Birk O., Douek D., Elias D., Takacs K., Dewchand H., Gur S. A role of hsp60 in autoimmune diabetes: Analysis in a transgenic model. Proc Natl Acad Sci (USA) 1996; 93: 1032–1037
   PubMed Web of Science ®Google Scholar
• Zugel U., Schoel B., Yamamoto S., Hengel H., Mor-Ein B., Kaufmann S. H. E. Crossrecognition by CD8 T cell receptor alpha beta cytotoxic T lymphocytes of peptides in the self and the mycobacterial hsp60 which share intermediate sequence homology. Eur J Immunol 1995; 25: 451–458
   PubMedGoogle Scholar
• Gaston J. S. H., Deane K. H. 0., Jecock R. M., Pearce J. H. Identification of 2 Chlamydia trachomatis antigens recognized by synovial fluid T cells from patients with Chlamydia induced reactive arthritis. J Rheumatol 1996; 23: 130–136
   PubMed Web of Science ®Google Scholar
• Probst P., Hermann E., Meyer zum Buschenfelde K. H., Fleischer B. Multiclonal synovial T-cell response to Yersinia-enterocolitica in reactive a –the Yersinia 61-kDa heat-shock protein is not the major target antigen. J Infect Dis 1993; 167: 385–391
   PubMed Web of Science ®Google Scholar
• Life P. F., Bassey E. O. E., Gaston J. S. H. T-cell recognition of bacterial heat-shock proteins in inflammatory arthritis. Immunol Rev 1991; 121: 113–135
   PubMedGoogle Scholar
• Mertz A., Lauster R., Braun J., Sieper J. Synovial T cell response to heat shock protein hsp60 of Yersinia enterocolitica in yersinia-arthritis patients. Arthritis Rheum 1996; 39: S299
   Google Scholar
• Shanafelt M., Hindersson P., Soderberg C, Mensi N., Turck C, Webb D. T cell and antibody reactivity with the Borrelia burgdorferi 60 kDa heat shock protein in Lyme arthritis. J Immunol 1991; 146: 3985–92
   PubMedGoogle Scholar
• Goupille P., Poet J. L., Jattiot F., Mattei J. P., Vedere V., Tonolli Serabian I. Three cases of arthritis after BCG therapy for bladder cancer. Clin Exp Rheumatol 1994; 12: 195–7
   PubMedGoogle Scholar
• Gaston J., Young J., Ramsey S., Scott D. Specificity of synovial fluid T cells in iatrogenic human adjuvant arthritis. Arthritis Rheum 1996; 39: S149
   Google Scholar
• Hermann E., Lohse A. W., van der Zee R., van Eden W., Mayet W. J., Probst P. Synovial fluid derived Yersinia reactive T cells responding to human 65 kDa heat shock protein and heat stressed antigen presenting cells. Eur J Immunol 1991; 21: 2139–43
   PubMed Web of Science ®Google Scholar
• Deane K., Jecock R., Pearce J., Gaston J. Mapping a DR4-restricted T cell epitope in chlamydia hsp60 –implications for reactive arthritis pathogenesis. Arthritis Rheum 1996; 39: SI15
   Google Scholar
• Beatty W. L., Belanger T. A., Desai A. A, Morrison R. P., Byrne G. I. Tryptophan depletion as a mechanism of gamma interferon-mediated chlamydial persistence. Infect Immun 1994; 62: 3705–3711
   PubMed Web of Science ®Google Scholar
• Beatty W. L., Byrne G. I., Morrison R. P. Morphologic and antigenic characterization of interferon gamma-mediated persistent Chlamydia trachomatis infection in vitro. Proc Natl Acad Sci (USA) 1993; 90: 3998–4002
   PubMed Web of Science ®Google Scholar
• Nanagara R., Li F., Beutler A., Hudson A., Schumacher H. R. Alteration of Chlamydia trachomatis biologic behavior in synovial membranes: Suppression of surface antigen production in reactive arthritis and Reiter's syndrome. Arthritis Rheum 1995; 38: 1410–1417
   PubMedGoogle Scholar
• Hughes R., Keat A. Reactive arthritis: the role of bacterial antigens in inflammatory arthritis. Baillieres Clin Rheumatol 1992; 6: 285–308
   PubMedGoogle Scholar
• Taylor-Robinson D., Gilroy C, Thomas B., Keat A. Detection of Chlamydia trachomatis DNA in joints of reactive arthritis patients by polymerase chain reaction. Lancet 1992; 340: 81–2
   PubMed Web of Science ®Google Scholar
• Branigan P. J., Gerard H. C, Hudson A. P., Schumacher H. R. Comparison of synovial tissue and synovial fluid as the source of nucleic acids for detection of Chlamydia trachomatis by polymerase chain reaction. Arthritis Rheum 1996; 39: 1740–1746
   PubMed Web of Science ®Google Scholar
• Morrison R. Chlamydial hsp60 and the immuno-pathogenesis of chlamydial disease. Semin Immunol 1991; 3: 25–33
   PubMedGoogle Scholar
• Noll A., Autenrieth I. B. Yersinia-hsp60-reactive T cells are efficiently stimulated by peptides of 12 and 13 amino acid residues in a MHC class II (I-A(b))-restricted manner. Clin Exp Immunol 1996; 105: 231–237
   PubMedGoogle Scholar
• Life P., Hassell A., Williams K., Young S., Bacon P., Southwood T. Responses to Gram negative enteric bacterial antigens by synovial T cells from patients with juvenile chronic arthritis –recognition of heat shock protein hsp60. J Rheumatol 1993; 20: 1388–1396
   PubMed Web of Science ®Google Scholar
• Albani S., Tuckwell J. E., Esparza L., Carson D. A., Roudier J. The susceptibility sequence to rheumatoid arthritis is a cross-reactive B cell epitope shared by the Escherichia coli heat shock protein dnaJ and the histocompatibility leukocyte antigen DRB10401 molecule. J Clin Invest 1992; 89: 327–31
   PubMed Web of Science ®Google Scholar
• Auger I., Escola J., Gorvel J., Roudier J. HLA-DR4 and HLA-DR10 motifs that carry susceptibility to rheumatoid arthritis bind 70-kD heat shock proteins. Nature Medicine 1996; 2: 306–310
   PubMed Web of Science ®Google Scholar
• Albani S., Keystone E. C., Nelson J. L., Oilier W. E., La Cava A., Montemayor A. C. Positive selection in autoimmunity: abnormal immune responses to a bacterial dnaJ antigenic determinant in patients with early rheumatoid arthritis. Nature Medicine 1995; 1: 448–52
   PubMed Web of Science ®Google Scholar
• Albani S., Ravelli A., Massa M., Debenedetti F., Andree G., Roudier J. Immune responses to the Escherichia coli dnaJ heat shock protein in juvenile rheumatoid arthritis and their correlation with disease activity. J Pediatrics 1994; 124: 561–565
   PubMed Web of Science ®Google Scholar
• Lai S., Lan J. L., Yu C. L., Lin R. H. A dominant human leucocyte antigen DR4-Dwl5 restricted mycobacterial 65 kDa antigen-specific T-cell immunity in Chinese patients with rheumatoid arthritis. Brit J Rheumatol 1995; 34: 498–506
   PubMedGoogle Scholar
• Gaston J., Life P., Bailey L., Bacon P. In vitro responses to a 65kD mycobacterial protein by synovial T cells from inflammatory arthritis patients. J Immunol 1989; 143: 2594–2600
   Google Scholar
• Pope R., Lovis R., Gupta R. Activation of synovial fluid T lymphocytes by 60 kd heat shock proteins in patients with inflammatory synovitis. Arthritis Rheum 1992; 35: 43–8
   PubMedGoogle Scholar
• Res P., Schaar C, Breedveld F., van Eden W., van Embden J., Cohen I. Synovial fluid T cell reactivity against 65 kD heat shock protein of mycobacteria in early chronic arthritis. Lancet 1988; 2: 478–80
   PubMed Web of Science ®Google Scholar
• Res P. C, Telgt D., van Laar J. M., Pool M. 0., Breedveld F. C., De Vries R. R. High antigen reactivity in mononuclear cells from sites of chronic inflammation. Lancet 1990; 336: 1406–8
   PubMed Web of Science ®Google Scholar
• Fischer H., Sharrock C, Colston M., Panayi G. Limiting dilution analysis of proliferative T cell responses to mycobacterial 65 kDa heat shock protein fails to show significant frequency differences between synovial fluid and peripheral blood of patients with rheumatoid arthritis. Eur J Immunol 1991; 21: 2937–41
   PubMed Web of Science ®Google Scholar
• Li S., Quayle A., Shen Y., Kjeldsen K. J, Oftung F., Gupta R. Mycobacteria and human heat shock protein specific cytotoxic T lymphocytes in rheumatoid synovial inflammation. Arthritis Rheum 1992; 35: 270–81
   PubMedGoogle Scholar
• Quayle A. J., Black W. K., Li S. G., Kjeldson-Kragh J., Oftung F., Sioud M. Peptide recognition, T cell receptor usage and HLA restriction of human heat-shock protein 60 and mycobacterial 65-kDa hsp-reactive T cell clones from rheumatoid synovial fluid. Eur J Immunol 1992; 22: 1315–1322
   PubMed Web of Science ®Google Scholar
• Gaston J., Life P., van der Zee R., Jenner P., Colston M., Tonks S. Epitope specificity and MHC restriction of rheumatoid arthritis synovial T cell clones which recognize a mycobacterial 65 kDa heat shock protein. Int Immunol 1991; 3: 965–72
   PubMed Web of Science ®Google Scholar
• De Graeff Meeder E., van der Zee R., Rijkers G., Schu-Urman H., Kuis W., Bijlsma J. W. Recognition of human 60 kD heat shock protein by mononuclear cells from patients with juvenile chronic arthritis. Lancet 1991; 337: 1368–72
   PubMedGoogle Scholar
• De Graeff Meeder E. R., van Eden W., Rijkers G. T., Prakken B. J., Kuis W., Voorhorstogink M. M. Juvenile chronic arthritis: T cell reactivity to human hsp60 in patients with a favorable course of arthritis. J Clin Invest 1995; 95: 934–940
   PubMedGoogle Scholar
• Prakken A., van Eden W., Rijkers G., Kuis W., Toebes E., De Graff Meeder E. Autoreactivity to human heat shock protein 60 predicts disease remission in oligo-articular juvenile rheumatoid arthritis. Arthritis Rheum 1996; 39: 1826–1832
   PubMed Web of Science ®Google Scholar