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Autoimmunity Volume 27, 1998 - Issue 3
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Original Article

Evidence for Carbimazole as an Antioxidant?

Rhoda Wilson Departments of Medicine and Pathological Biochemistry, Glasgow Royal Infirmary and Department of Chemistry, University of Strathclyde, 10 Alexandra Parade, Glasgow, G31 2ER
,
Linda Buchanan Departments of Medicine and Pathological Biochemistry, Glasgow Royal Infirmary and Department of Chemistry, University of Strathclyde, 10 Alexandra Parade, Glasgow, G31 2ER
,
William D. Fraser Departments of Medicine and Pathological Biochemistry, Glasgow Royal Infirmary and Department of Chemistry, University of Strathclyde, 10 Alexandra Parade, Glasgow, G31 2ER
,
Carol Jenkins Departments of Medicine and Pathological Biochemistry, Glasgow Royal Infirmary and Department of Chemistry, University of Strathclyde, 10 Alexandra Parade, Glasgow, G31 2ER
,
William E. Smith Departments of Medicine and Pathological Biochemistry, Glasgow Royal Infirmary and Department of Chemistry, University of Strathclyde, 10 Alexandra Parade, Glasgow, G31 2ER
,
John Reglinski Departments of Medicine and Pathological Biochemistry, Glasgow Royal Infirmary and Department of Chemistry, University of Strathclyde, 10 Alexandra Parade, Glasgow, G31 2ER
,
John A. Thomson Departments of Medicine and Pathological Biochemistry, Glasgow Royal Infirmary and Department of Chemistry, University of Strathclyde, 10 Alexandra Parade, Glasgow, G31 2ER
&
James H. McKillop Departments of Medicine and Pathological Biochemistry, Glasgow Royal Infirmary and Department of Chemistry, University of Strathclyde, 10 Alexandra Parade, Glasgow, G31 2ER
 show all
Pages 149-153 | Received 24 Mar 1997, Accepted 21 Jul 1997, Published online: 07 Jul 2009

References

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  • Weetman A. P., Holt M. E., Campbell A. K., Hall R., McGregor A. M. Methimazole and generation of oxygen radicals by monocytes: potential role in immunosu-pression. British Medical Journal 1984; 288: 518–520
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  • Reglinski J., Smith W. E., Wilson R., Buchanan L. M., McKillop J. H., Thomson J. A. Spin echo NMR resonance studies on intact erythrocytes: changes in cellular metabolism as a consequence of Carbimazole therapy. Clinical Endocrinology 1992 1992; 37: 319–324
  • Ellman G. L. Tissue sulphydryl groups. Archives of Biochemistry and Biophysics 1959 1959; 82: 70–77
  • Menden E. E., Biorano J. M., Murthy L., Petering H. G. Modification of a phenylenediamine oxidase. Method to permit caeruloplasmin determinations. Analytical Letters 1977; 197–204
  • Balazs C., Kiss E., Leovey E., Farid N. R. The immunosuppressive effect of Methimazole on cell-mediated immunity is mediated by its capacity to inhibit peroxidase and to scavenge free oxygen radicals. Clinical Endocrinology 1986; 25: 7–16

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