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Original Article

Prevalence of β-cell and Thyroid Autoantibody Positivity in Schoolchildren during Three-Year Follow-up

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Pages 175-185 | Received 25 May 1999, Accepted 20 Aug 1999, Published online: 07 Jul 2009

References

  • Bachrach L., Foley T., Jr. Thyroiditis in children. Pediatr. Rev. 1989; 11: 184–91
  • van Vielet G., Delange, Goiter F., thyroiditis. Pediatric Endocrinology, 2nd edn, Bertrand, Rappaport, Sizonenko. Williams & Wilkins, Baltimore 1993; 270–6
  • Fisher D. The thyroid. Clinical Pediatric Endocrinology, S. Kaplan. Saunders, Philadelphia 1990; 87–126
  • Baekkeskov S., Nielsen J. H, Marner B., Bilde T., Ludvigsson J., Lernmark A. Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins. Nature 1982; 298: 167–9
  • Baekkeskov S., Landin M., Kristensen J., Srikanta S., Bruining G., Mandrup-Poulsen T., et al. Antibodies to a Mr 64000 human islet cell antigen precede the clinical onset of insulin dependent diabetes. J. Clin. Invest 1987; 79: 926–34
  • Baekkeskov S., Aanstoot H. K., Christgau S., Reetz A., Solimena M., Cascalco M., et al. Identification of the 64k autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase. Nature 1990; 347: 151–6
  • Christie M., Landin-Olsson M., Sundkvist G., Dahlquist G., Lernmark A. Antibodies to a Mr-64000 islet cell protein in Swedish children with newly diagnosed type 1 (insulin-dependent) diabetes. Diabetologia 1988; 31: 597–602
  • Atkinson M., Maclaren N. Islet cell antigens in insulin-dependent diabetes. J. Clin. Invest 1993; 92: 1608–16
  • Palmer J. P., Asplin C. M., Clemons P., Lyen K., Tatpati O., Raghu P. K., et al. Insulin antibodies in insulin-dependent diabetics before insulin treatment. Science 1983; 222: 1337–9
  • Dean B. M, Becker F., McNally J. M, Tarn A. C, Schwartz G., Gale E. A.M., et al. Insulin antibodies in the prediabetic period: correlation with islet cell antibodiesdevelopment of diabetes. Diabetologia 1986; 29: 339–42
  • Wilkin T., Armitage M., Casey C., Pyke D., Hoskins P., Rodier M., et al. Value of insulin autoantibodies as serum markers for insulin-dependent diabetes mellitus. Lancet 1985; 1: 480–2
  • Palmer J. P., Lernmark Å. Pathophysiology of type 1 (insulin-dependent) diabetes. Diabetes Mellitus, H Rifkin, D. Porte. Elsevier, New York 1990; 414–35
  • Lernmark Å. Islet cell antibodies-theoreticalpractical implications. Diabetic Medicin 1987; 4: 285–92
  • Bottazzo G. F, Florin-Christensen A., Doniach D. Islet cell antibodies in diabetes mellitus with autoimmune polyendocrine deficiencies. Lancet 1974; 2: 1279–83
  • Lendrum R., Walker G., Cudworth A. G, Theo-Phanides C, Pyke D. A, Bloom A., et al. Islet cell antibodies in diabetes mellitus. Lancet 1976; 2: 1273–6
  • Spencer K. M, Tarn A., Dean B. M, Lister J., Bottazzo G. F. Fluctuating islet cell autoimmunity in unaffected relatives of patients with insulin-dependent diabetes. Lancet 1984; 1: 764–6
  • Landing B., Pettit M., Wiens R., Knowles H., Guest G. Antithyroid AntibodyChronic Thyroiditis in Diabetes. J. Clin. Endocrinol. Metab 1963; 23: 119–20
  • Lindberg B., Ivarsson S. A., Ericsson U. B., Ljung R. High prevalence of thyroid antibodies at diagnosis of Type 1 diabetes mellitus in Swedish children. J. Lab. Clin. Med. 1997; 130: 585–9
  • Nuovo J., Baker J., Wartofsky L., Lukes Y., Burman K. Autoantibodies to insulin are present in sera of patients with autoimmune thyroid disease. Diabetes 1988; 37: 317–20
  • Kawasaki E., Abiru N., Yano M., et al. Autoantibodies to glutamic acid decarboxylase in patients with autoimmune thyroid disease: relation to competitive insulin autoantibodies. J Autoimmun 1995; 8: 633–43
  • Vardi P., Modan-Mozes D., Ish-Shalom S., Soloveitzik L., Barzilai D., Modan M. Low titer, competitive insulin autoantibodies are spontaneously produced in autoimmune diseases of the thyroid. Diabetes Res. Clin. Pract 1993; 21: 161–6
  • Ng W., Thai A., Lui K., Cheah J. Occurrence of antibodies to insulin in patients with autoimmune thyroid disease. Ann. Acad. Med. Singapore 1993; 22: 544–8
  • Lindberg B., Ahlfors O K., Carlsson A., Ericsson U. B., Landin-Olsson M., Lernmark A., et al. Prior exposure to measles, mumps,rubella - but not vaccination during adolescence - correlates to the prevalence of pancreaticthyroid autoantibodies. Pediatrics 1999; 104/e12: 1–5, [www http://www.pediatrics org/ cgi/content/full/104/l/el2]
  • Riley W. J, Maclaren N. K, Krischer J., Spillar R. P, Silverstein J. H, Schatz D. A., et al. A prospective study of the development of diabetes in relatives of patients with insulin-dependent diabetes. TV. Engl. J. Med. 1990; 323: 1167–72
  • Bingley P. J, Christie M. R, Bonifacio E., Bonifanti R., Shattock M., Fonte M. T., et al. Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives. Diabetes 1994; 43: 1304–10
  • Lipton R., Atchison J., Dorman J., et al. Genetic, immunologicalmetabolic determinants of risk for Type 1 diabetes mellitus in families. Diabetic Medicine 1992; 9: 224–32
  • Bloom A., Hayes T., Gamble D. Register of newly diagnosed diabetic children. Br. Med. J. 1975; 2: 580–3
  • Dahlquist G., Blom L., Lönnberg G. The Swedish childhood diabetes study - a multivariate analysis of risk determinants for diabetes in different age groups. Diabetohgia 1991; 34: 757–62
  • Schatz D., Krischer J., Home G., et al. Islet cell antibodies predict insulin-dependent diabetes in United States school age children as powerful as in unaffected relatives. J. Clin. Invest 1994; 93: 2403–7
  • Lévy-Marchal C, Tichet J., Fajardy I., Gu X., Dubois F., Czernichow P. Islet cell antibodies in normal French schoolchildren. Diabetohgia 1992; 35: 577–82
  • Bingley P., Bonifacio E., Shattock M., et al. Can islet cell antibodies predict IDDM in the general population?. Diabetes Care 1993; 16: 43–50
  • Tandon N., Zhang L., Weetman A. HLA associations with Hashimoto's thyroiditis. Clin. Endocrinol 1991; 40: 3836
  • Bazarova E., Efuni S., Polianskaia I., Fedoseeva G., Okeanova T. Association of antigens of the HLA systemHashimoto's thyroiditis. Probl. Endokrinol 1988; 34: 14–16
  • Farid N., Thompson C. HLAautoimmune endocrine disease. Mol. Biol. Med. 1986; 3: 85–97
  • Bogner U., Badenhoop K., Peters H., Schmieg D., Mayr W., Usadel K., et al. HLA-DR/DQ gene variation in nongoitrous autoimmune thyroiditis at the serologicalmolecular level. Autoimmunity 1992; 14: 155–8
  • Jenkins D., Penny M., Fletcher J., Jacobs K., Mijovic C, Franklyn J., et al. HLA class II gene polymorphism contributes little to Hashimoto's thyroiditis. Clin. Endocrinol 1992; 37: 141–5, 1992
  • Wolf E., Spencer K., Cudworlh A. The genetic susceptibility to Type 1 (insulin-dependent) diabetes: analysis of the HLA-DR association. Diabetohgia 1983; 24: 224–30
  • Platz P., Jacobson B., Morling N., et al. HLA-DDR-antigens in genetic analysis of insulin-dependent diabetes mellitus. Diabetohgia 1981; 21: 108–15
  • Grubin C. E., Daniels T., Toivola B., Landin-Olsson M., Hagopian W. A, Li L., et al. A novel radioligand binding assay to determine diagnostic accuracy of isoform-specific glutamic acid decarboxylase antibodies in childhood IDDM. Diabetohgia 1994; 37: 344–50
  • Falorni A., Örtqvist E., Persson B., Lernmark Å. Radioimmunoassays for glutamic acid decarboxylase (GAD65)GAD65 autoantibodies using 35S or 3H recombinant human ligands. J. Immunol. Meth 1995; 186: 89–99
  • Madsen O., Landin-Olsson M., Bille G., Sundkvist G., Lernmark Å., Dahlqvist G., et al. A two-colour immunofluorescence test with a monoclonal human proinsulin antibody improves the assay for islet cell antibodies. Diabetohgia 1986; 29: 115–18
  • Landin-Olsson M., Sundkvist G., Lernmark Å. Prolonged incubation in the two-colour immunofluorescence test increases the prevalencetitres of islet cell antibodies in Type 1 (insulin-dependent) diabetes mellitus. Diabetohgia 1987; 30: 327–32
  • Bonifacio E., Lernmark A., Dawkins, et al. Scrum exchangeuse of dilutions have improved precision of measurement of islet cell antibodies. J. Immunol. Meth 1988; 106: 83–8
  • Greenbaum C. J, Palmer J. P, Nagataki S., Yamaguchi Y., Molenaar J. L, Van Beers W. A., et al. Improved specificity of ICA assays in the fourth international immunology of diabetes serum exchange workshop. Diabetes 1992; 42: 1570–4
  • Ericsson U. B., Larsson L, Murne A., Thorel I. A new sensitive immunosorbent radioassay for the detection of circulating antibodies to polypeptide hormonesprotein. Seand. J. Clin. Lab Invest 1984; 44: 487–93
  • Kockum I., Wassmuth R., Holmberg E., Michelsen B., Lernmark Å. HLA-DQ primarily confers protectionHLA-DR susceptibility in type 1 (insulin-dependent) diabetes in population-based affected familiescontrol. Am. J. Hum. Genet 1993; 53: 150–67
  • Olerup O., Zetterquist H. HLA-DR typing by PCR amplification with sequence-specific primers (PCR-SSP) in 2h: An alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tissue Antigens 1992; 39: 225–35
  • Christie M., Delovitch T. L. Persistence of antibodies to a 64,000-Mr islet cell protein after onset of type 1 diabetes. Diabetes 1990; 39: 653–9
  • Yokota I., Matsuda J., Naito E., Ito M., Shima K., Kuroda Y. Comparison of GADICA512/1A-2 antibodies atafter the onset of IDDM. Diabetes Care 1998; 21: 49–52
  • Sundkvist G., Hagopian W. A, Landin-Olsson M., Lernmark A, Ohlsson L., Ericsson C., et al. Islet cell antibodies (ICA) but not glutamic acid decarboxylase antibodies (GAD65-Ab) are decreased by plasmapheresis in patients with newly diagnosed insulin-dependent diabetes mellitus (IDDM). J. Clin. Endocrinol. Metah 1994; 78: 1159–65
  • Landin-Olsson M., Palmer J., Lernmark A., et al. Predictive value of islet cellinsulin autoantibodies for type I (insulin-dependent) diabetes mellitus in a population-based study of newly-diagnosed diabeticmatched control children. Diabetohgia 1992; 35: 1068–73
  • Casali P., Nakamura M., Ginsberg-Fcllener Notkins F. A. Frequency of B cells committed to the production of antibodies to insulin in newly diagnosed patients with IDDMgeneration of high affinity human monoclonal IgG to insulin. J Immunol 1990; 1: 3741–7
  • Landin-Olsson M., Karlsson A., Dahlquist G., Blom L., Lernmark Å, Sundkvist G. Islet cellother organ-specific autoantibodies in all children developing type 1 (insulin-dependent) diabetes mellitus in Sweden during one yearin matched controls. Diabetohgia 1989; 32: 387–95
  • Lévy-Marchal C, Dubois F., Noël M., Tichet J., Czernichow P. Immunogenetic. DeterminantsPrediction of IDDM in French schoolchildren. Diabetes 1995; 44: 1029–32
  • Boem B., Manfras B., eißler J., et al. Epidemiologyimmunogenetic background of islet cell antibody-positive nondiabetic schoolchildren. Diabetes 1991; 40: 1435–9
  • Karjalainen J. Islet cell antibodies as predictive markers for IDDM in children with high background incidence of disease. Diabetes 1990; 39: 1144–50
  • Riley W., Maclaren N. Islet-cell antibodies are seldom transient. Lancet 1984; i: 1351–2
  • Gardas A. Laboratory tests: levels of T3, T4, TSHantithyroid gland autoantibodies in the Polish population. Endokrynol. Pol. 1991; 42: 353–8
  • Ericsson U. B., Ivarsson S. A. Thyroglobulin autoantibodies in childrenadolescents: Its relation to thyroid disease. Peel. Asthma All Immunol 1989; 3: 233–6
  • Verge C, Gianni R., Kawasaki E., et al. Number of autoantibodies rather than particular autoantibody specificities determines risk of Type 1 diabetes. J. Autoimm 1996; 9: 379–83
  • Christie M., Roll U., Payton M., Hatfield E., Ziegler A. Validity of screening for individuals at risk for type 1 diabetes by combined analysis of antibodies to recombinant proteins. Diabetes Care 1997; 20: 965–70

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