11
Views
1
CrossRef citations to date
0
Altmetric
Original Article

Differential Expression of p95vav in Primary Lymphoid Tissue of BB Rats Congenic for the Lymphopenia Gene

Pages 37-42 | Received 27 Aug 1998, Accepted 31 Oct 1998, Published online: 07 Jul 2009

References

  • Bieg S., Koike G., Jiang J., Klalt L., Pettersson A., MacMurray A. J., Jacob H. J., Lander E. S., Lernmark A. Genetic isolation of iddm 1 on chromosome 4 in the BioBreeding (BB) rat. Mammalian Genome 1998; 9: 324–326
  • Jacob H., Pettersson A., Wilson D., Aernmark R., Lander E. S. Genetic dissection of autoimmune type 1 diabetes in the BB rat. Nature Genetics 1992; 2: 56–60
  • Pettersson A., Jacob H., Aernmark R. Lessons from the animal models: The BB rat. Diabetes Prediction, Prevention und Genetic Counseling in IDDM, J. P. Palmer. John Wiley & Sons Ltd. 1996; 182–200
  • Sellins K. S., Gold D. P., Bellgrau D. Resistance to tolerance induction in the diabetes-prone Biobreeding rat as one manifestation of abnormal responses to super-antigens. Diabetologia 1996; 39: 28–36
  • Bellgrau D., Redd J. M., Sellins K. S. Peculiar T-cell signaling does not preclude positive selection in the diabetes-prone BB rat. Diabetes 1994; 43: 47–52
  • Zadeh H. H., Greiner D. L., Wu D. Y., Tausche F., Goldschneider I. Abnormalities in the export and fate or recent thymic emigrants in diabetes-prone BB/W rats. Autoimmunity 1996; 24: 35–46
  • Bieg S., Moller C., Olsson T., Lernmark A. The lymphopenia (Lyp) gene controls the intrathymic cytokine ratio in congenic BioBreeding rats. Diabetologia 1997; 40: 786–792
  • Plamondon C., Kottis V., Brideau C., Metroz-Dayer M. D., Poussier P. Abnormal thymocyte maturation in spontaneously diabetic BB rats involves the deletion of CD4-8+ cells. J. Immunol. 1990; 144: 923–928
  • Leclercq G., Plum J. Thymic and extrathymic T-cell development. Leukemia 1996; 10: 1853–1859
  • Kisielow P., von Boehmer H. Development and selection of T cells: facts and puzzles. Adv. Immunol. 1995; 58: 187–209
  • Bustelo X. R. The VAV family of signal transduction molecules. Crit. Rev. Oncog. 1996; 7: 65–88
  • Turner M., Mee P. J., Walters A. E., Quinn M. E., Mellor A. L., Zamoyska R., Tybulewicz V. L.J. A requirement for the rho-family GTP exchange factor vav in positive and negative selection of thymocytes. Immunity 1997; 7: 451–460
  • Tarakhovsky A., Turner M., Schaal S., Mee P. J., Duddy L. P., Rajewsky K., Tybulewicz V. L. Defective antigen receptor-mediated proliferation of B and T cells in the absence of Vav. Nature 1995; 374: 467–470
  • Zhang R., Alt F. W., Davidson L., Orkin S. H., Swat W. Defective signalling through the T- and B-cell antigen receptors in lymphoid cells lacking the vav proto-oncogene. Nature 1995; 374: 470–473
  • Margolis B., Hu P., Katzav S., Li W., Oliver J. M., Ullrich A., Weiss A., Schlessinger J. Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs. Nature 1992; 356: 71–74
  • Bustelo X. R., Rubin S. D., Suen K. L., Carrasco D., Barbacid M. Developmental expression of the vav proto-oncogene. Cell Growth Differ. 1993; 4: 297–308
  • Wu J., Katzav S., Weiss A. A functional T-cell receptor signaling pathway is required for p95vav activity. Mol. Cell Biol. 1995; 15: 4331–4346
  • Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 1987; 162: 156–159

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.