122
Views
13
CrossRef citations to date
0
Altmetric
Original Article

Humoral Response Against Myelin Antigens in Two Strains of Rats with Different Susceptibility to Experimental Allergic Encephalomyelitis (EAE)

, &
Pages 129-137 | Received 20 May 1998, Published online: 07 Jul 2009

References

  • Maggio B., Cumar F. A., Roth G. A., Monferrán C. G., Fidelio G. D. Neurochemical and model membrane studies in demyelinating diseases. Acta Neuropathol. (Berlin) 1983; 9(Suppl)71–85
  • Raine C. S. Experimental allergic encephalomyelitis and experimental allergic neuritis. Handb. Clin. Neurol. 1985; 47: 429–466
  • Tabira T. Autoimmune demyelination in the central nervous system. Ann. NY Acad. Sci. 1988; 540: 187–201
  • Hughes R. A.C., Stedronska J. The susceptibility of rat strains to experimental allergic encephalomyelitis. Immunology 1973; 24: 879–884
  • Roth G. A., Obata K. Experimental allergic encephalomyelitis: Dissociation of immunochemical and clinicopathological responses in two strains of rats. Neurochem. Int. 1991; 19: 213–220
  • Encinas J. A., Weiner H. L., Kuchroo V. K. Inheritance of susceptibility to experimental autoimmune encephalomyelitis. J. Neurosci. Res. 1996; 45: 655–669
  • de Brito F. B., Hanahoe T. H.P. Susceptibility of two colonies of Wistar rats to inflammation, with particular reference to delayed hypersensitivity. Int. Archs. Allergy Appl. Immun. 1983; 72: 164–169
  • Tabira T., Kira J.-I. Strain and species differences of encephalitogenic determinants of myelin basic protein and proteolipid apoprotein. Myelin: Biology and Chemistry, R. E. Martenson. CRC Press, Boca Raton, FL 1992; 783–800
  • Happ M. P., Wettstein P., Dietzschold B., Heber-Katz E. Genetic control of the development of experimental allergic encephalomyelitis in rats. Separation of MHC and non-MHC gene effects. J. Immunol. 1988; 141: 1489–1494
  • Fugger L., Liang J., Gautam A., Rothbard J. B., Mcdevitt H. O. Quantitative analysis of peptides from myelin basic protein binding to the MHC class II protein, I-A (U), which confers susceptibility to experimental allergic encephalomyelitis. Mol. Med. 1996; 2: 181–188
  • Sternberg E. M., Hill J. M., Chrousos G. P., Kamilaris T., Listwak S. J., Gold P. W., Wilder R. L. Inflammatory mediator-induced hypothalamic-pituitary-adrenal axis activation is defective in streptococcal cell wall arthritis-susceptible Lewis rats. Proc. Natl. Acad. Sci. USA 1989; 86: 2374–2378
  • Hashim G. A., Day E. D. Role of antibodies in T cell-mediated experimental allergic encephalomyelitis. J. Neurosci. Res. 1988; 21: 1–5
  • Karpus W. J., Swanborg R. H. Protection against experimental allergic encephalomyelitis requires both CD4+ T-suppressor cells and myelin basic-primed B cells. J. Neuroimmunol. 1991; 33: 173–177
  • Willenborg D. O., Sjollema P., Danta G. Immunoglobulin deficient rats as donors and recipients of effector cells of allergic encephalomyelitis. J. Neuroimmunol. 1986; 11: 93–103
  • Myers K. J., Sprent J., Dougherty J. P., Ron Y. Synergy between encephalitogenic T cells and myelin basic protein-specific antibodies in the induction of experimental autoimmune encephalomyelitis. J. Neuroimmunol. 1992; 41: 1–8
  • Wolf S. D., Dittle B. N., Hardardottir F., Janeway C. A. Experimental autoimmune encephalomyelitis induction in genetically B cell-deficient mice. J. Exp. Med. 1996; 184: 2271–2278
  • McFarlin D. E., Hsu S. C., Slemenda S. B., Chou F. C., Kibler R. F. The immune response against myelin basic protein in two strains of rat with different genetic capacity to develop experimental allergic encephalomyelitis. J. Exp. Med. 1975; 141: 72–81
  • Roth G. A., Yu R. K., Bornstein M. B. Chemical analysis of organotypic cultures of mouse spinal cord in normal, demyelinative, and nondemyelinative conditions. J. Neurochem. 1983; 41: 1710–1717
  • Nishizawa M., Tanaka M., Inizuka T., Tanaka K., Baba H., Miyatami N., Sato S., Miyatake T. Production and characterization of monoclonal antibodies against myelin-associated glycoprotein. J. Neurochem. 1986; 47: 1893–1900
  • Rivero V. E., Maccioni M., Bucher A. E., Roth G. A., Riera C. M. Suppression of experimental autoimmune encephalomyelitis (EAE) by intraperitoneal administration of soluble myelin antigens in Wistar rats. J. Neuroimmunol. 1997; 72: 3–10
  • Lando Z., Teitelbaum D., Arnon R. Induction of EAE in genetically resistant strains of mice. Nature 1980; 287: 551–552
  • Beraud E., Reshef T., Vandenbark A. A., Offner H., Friz R., Chou C.-H. J., Bernard D., Cohen I. R. Experimental autoimmune encephalomyelitis mediated by T lymphocyte lines: genotype of antigen-presenting cells influences immuno dominant epitope of basic protein. J. Immunol. 1986; 136: 511–515
  • Trotter J., Zamvill A. A., Steinman L. Comparison of antigen specificity, class II major histocompatibility complex restriction and in vivo behavior of myelin basic protein-specific T cell lines and clones derived from (BALE/c × SJL/J) mice. J. Immunol. 1987; 139: 1834–1839
  • Abromson-Leeman S., Hayashi M., Martin C., Sobel R., Al-Sabbagh A., Weiner H., Dorf M. E. T cell response to myelin basic protein in experimental autoimmune encephalomyelitis-resistant BALB/c mice. J. Neuroimmunol. 1993; 45: 89–96
  • Mustafa M., Vingsbo C., Olsson T., Issazadeh S., Ljungdahl A., Holmdahl R. Protective influences on experimental autoimmuneencephalomyelitis by MHCclass I and Class II allcles. J. Immunol. 1994; 153: 3337–3344
  • Issazadeh S., Kjellen P., Olsson T., Mustafa M., Holmdahl R. Major histocompatibility complex-controlled protective influences on experimental autoimmune encephalomyelitis are peptide specific. Eur. J. Immunol. 1997; 27: 1584–1587
  • Mostarica-Stojkovic M., Petrovic M., Lukic M. L. Resistance to the induction of EAE in AO rats: its prevention by the pre-treatment with cyclophosphamide or low dose of irradiation. Clin. Exp. Immunol. 1982; 50: 311–317
  • Abromson-Leeman S., Alexander J., Bronson R., Carroll J., Southwood S., Dorf M. E. Experimental allergic encephalomyelitis-resistant mice have highly encephalitogenic myelin basic protein (MBP)-specific T cell clones that recognize a MBP peptide with high affinity for MHC class II. J. Immunol. 1995; 154: 388–398
  • Shaw M. K., Kim C., Ho K. H., Lisak R. P., Tse H. Y. A combination of adoptive transfer and antigenic challenge induces consistent murine autoimmune encephalomyelitis in C57BL/6 mice and other reputed resistant strains. J. Neuroimmunol. 1992; 39: 139–150
  • Levine S., Sowinski R. Allergic encephalomyelitis in the reputedly resistant Brown Norway strain of rats. J. Immunol. 1975; 114: 597–601
  • Saudi A., Kuhn J., Huygen K., De Kozak Y., Velu T., Goldman M., Druet P., Bellon B. Th2 activated cells prevent experimental autoimmune uveoretinitis, a Th1-dependant autoimmune disease. Eur. J. Immunol. 1993; 23: 3096–3103
  • Der Balian G. P., Slack J., Clevinger B. L., Bazin H., Davie J. M. Subclass restriction of murine antibodies. Antigens that stimulate IgG3 in mice stimulate IgG2c in rats. J. Exp. Med. 1980; 152: 209–218
  • Sayavey M. H., Akalin E., Hancok W. W., Russel M. E., Carpenter C. B., Linsley P. S., Turka L. A. CD 28-B7 blockade after allogenic challenge in vivo inhibits Th1 cytokines but spares Th2. J. Exp. Med. 1995; 181: 1869–1874
  • Smith L. A., Rumanjanek V. M. Transfer of protection against allergic encephalomyelitis from mother to offspring. Immunology 1984; 51: 201–204
  • MacPhee I. A., Day M. J., Mason D. W. The role of serum factors in the suppression of EAE evidence for immunoregulation by antibody to encephalitogenic peptide. Immunology 1990; 70: 527–534
  • Rott O., Bernard F., Cash E. Interleukin-10 prevents experimental allergic encephalornyelitis in rats. Eur. J. Immunol. 1994; 24: 1434–1440
  • Bach J.-F. Organ-specific autoimmunity. Immunol. Today 1995; 16: 353–355
  • Kumar V., Sercarz E. Dysregulation of potentially pathogenic self reactivity is crucial for the manifestation of clinical autoimmunity. J. Neurosci. Res. 1996; 45: 334–339
  • Slattery R. M., Miller J. F.A.P., Heath W. R., Charlton B. Failure of a protective major histocompatibility complex class II molecule to delete autoreactive T cells in autoimmune diabetes. Proc. Natl. Acad. Sci. USA 1993; 90: 10808–10810
  • Wen L., Roberts S. J., Viney J. L., Wong F. S., Mallick C., Findly R. C., Peng Q., Craft J. E., Owen M J., Hayday A. C. Immunoglobulin synthesis and generalized autoimmunity in mice congenitally deficient in αβ(+) T cells. Nature 1994; 369: 654–658
  • Ando D. G., Clayton J., Kono D., Urban J. L., Sercarz E. Encephalitogenic T cells in the B10.PL model of experimental allergic encephalornyelitis (EAE) are of Th1 lymphokine subtype. Cell Immunol. 1989; 124: 132–143
  • Racke M. K., Bonomo A., Scott D. E., Cannella B., Levine A., Raine C. S., Shevach E. M., Röcken M. Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease. J. Exp. Med. 1994; 180: 1961–1966
  • Karpus W. J., Gould K. E., Swanborg R. H. CD4+ suppressor cells of autoimmune encephalornyelitis respond to T cell receptor-associated determinants on effector cells by interleukin-4 secretion. Eur. J. Neurosci. 1992; 22: 1757–1763
  • Khoury S. J., Hancock W. W., Weiner H. L. Oral tolerance to myelin basic protein and natural recovery from experimental autoimmune encephalornyelitis are associated with downregulation of inflammatory cytokines and differential upregulation of transforming growth factor β, interleukin-4 and prostaglandin E in the brain. J. Exp. Med. 1992; 176: 1355–1364
  • Leonard J. P., Waldburger K. E., Goldman S. J. Prevention of experimental autoimmune encephalornyelitis by antibodies against Interleukin 12. J. Exp. Med. 1995; 181: 381–386
  • Kelso A. Th1 and Th2 subsets: paradigms lost?. Immunol. Today 1995; 16: 374–379

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.