Advanced search
Publication Cover
Immunopharmacology and Immunotoxicology Volume 32, 2010 - Issue 1
Submit an article Journal homepage
58
Views
15
CrossRef citations to date
0
Altmetric
Research Article

Tanshinone IIA protects against immune-mediated liver injury through activation of t-cell subsets and regulation of cytokines

Xiao-Yan QinLaboratory of Biotechnology and State Key Laboratory of Chinese ethnic minority traditional medicine, College of Life & Environmental Science, Minzu University of China, Beijing, ChinaCorrespondence[email protected]
,
Tang LiLaboratory of Biotechnology and State Key Laboratory of Chinese ethnic minority traditional medicine, College of Life & Environmental Science, Minzu University of China, Beijing, China
,
Li YanLaboratory of Biotechnology and State Key Laboratory of Chinese ethnic minority traditional medicine, College of Life & Environmental Science, Minzu University of China, Beijing, China
,
Qing-Shan LiuLaboratory of Biotechnology and State Key Laboratory of Chinese ethnic minority traditional medicine, College of Life & Environmental Science, Minzu University of China, Beijing, China
&
Yu TianXuanwu Division, Beijing Municipal Public security Bureau, Beijing, China
Pages 51-55 | Received 26 May 2009, Accepted 16 Jun 2009, Published online: 19 Feb 2010

References

  • Cheng, T.O. Cardiovascular effects of Danshen. Into J Cardio 2007; 121: 9–22.
  • Zhou, L.Z., Zoo, Z., Chow, M.S. Danshen: an overview of its ­chemistry, pharmacology, pharmacokinetics, and clinical use. J Clint Pharmacology 2005; 45: 1345–59.
  • Adams, J.D., Wang, R., Yang J., et al. Preclinical and clinical examinations of Salvia miltiorrhiza and its tensions in ischemic conditions. Chin Med 2006; 1: 3.
  • Liu, J.R., Chen, G.F., Shih, H.N., et al. Enhanced antioxidant bioactivity of Salvia miltiorrhiza (Danshen) products prepared using nanotechnology. Phytomedicine 2008; 15: 23–30.
  • Xiaohui, Z., Xinfeng, Z., Xin, Z., et al. Determination of the main bioactive ­metabolites of Radix salvia miltiorrhizae in compound Danshen dripping pills and the tissue distribution of Danshensu in rabbit by SPE-HPLC-MSn. J Sep Sci 2007; 30: 851–7.
  • Herkel, J., Schuchmann, M., Tiegs, G., et al. Immune-mediated liver injury. J Hepatol 2005; 42: 920–3.
  • Center, S.A. Chronic liver disease: current concepts of disease mechanisms. J Small Anim Pract 1999; 40: 106–14.
  • Gantner, F., Leist, M., Lohse, A.W., et al. Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor. Hepatology, 1995; 21: 190–8.
  • Abboud, G., Kaplowitz, N. Drug-induced liver injury. Drug Saf 2007; 30: 277–94.
  • Eksteen, B., et al. Immune-mediated liver injury. Semin Liver Dis 2007; 27: 351–66.
  • Kremer, A.E., Rust, C., Eichhorn, P., et al. Immune-mediated liver diseases: programmed cell death ligands and circulating apoptotic markers. Expert Rev Mol Diagn 2009; 9: 139–56.
  • Beldi, G., Banz, Y., Nowak, M., et al. Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A-induced hepatitis. Hepatology 2008; 48: 841–52.
  • Huang, W., Dong, Z., Wei H., et al. Selective elimination of hepatic natural killer T cells with concanavalin A improves liver regeneration in mice. Liver Int 2006; 26: 339–45.
  • Irshad, M. I., Khushboo, I., Singh, S. Hepatitis C virus (HCV): a review of immunological aspects. Int Rev Immunol 2008; 27: 497–517.
  • Ju, C. Immunological mechanisms of drug-induced liver injury. Curr Opin Drug Discov Dev 2005; 8: 38–43.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.