70
Views
2
CrossRef citations to date
0
Altmetric
Research Article

An analysis of the human and mouse CXCR5 gene introns

, , , , &
Pages 342-346 | Received 21 Jul 2010, Accepted 27 Jul 2010, Published online: 01 Sep 2010

References

  • Sverdlov, E.D. Perpetually mobile footprints of ancient infections in human genome. FEBS Lett. 1998, 428, 1–6.
  • Khodosevich, K., Lebedev, Y., Sverdlov, E. Endogenous retroviruses and human evolution. Comp. Funct. Genomics 2002, 3, 494–498.
  • Nelson, P.N., Carnegie, P.R., Martin, J., Davari Ejtehadi, H., Hooley, P., Roden, D., Rowland-Jones, S., Warren, P., Astley, J., Murray, P.G. Demystified. Human endogenous retroviruses. MP, Mol. Pathol. 2003, 56, 11–18.
  • Andersson, A.C., Svensson, A.C., Rolny, C., Andersson, G., Larsson, E. Expression of human endogenous retrovirus ERV3 (HERV-R) mRNA in normal and neoplastic tissues. Int. J. Oncol. 1998, 12, 309–313.
  • Tönjes, R.R., Czauderna, F., Kurth, R. Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K. J. Virol. 1999, 73, 9187–9195.
  • de Parseval, N., Heidmann, T. Human endogenous retroviruses: from infectious elements to human genes. Cytogenet. Genome Res. 2005, 110, 318–332.
  • Larsson, E., Andersson, G. Beneficial role of human endogenous retroviruses: facts and hypotheses. Scand. J. Immunol. 1998, 48, 329–338.
  • Daniel, R., Smith, J.A. Integration site selection by retroviral vectors: molecular mechanism and clinical consequences. Hum. Gene Ther. 2008, 19, 557–568.
  • Schaffer, D.V., Koerber, J.T., Lim, K.I. Molecular engineering of viral gene delivery vehicles. Annu. Rev. Biomed. Eng. 2008, 10, 169–194.
  • Nienhuis, A.W. Development of gene therapy for blood disorders. Blood 2008, 111, 4431–4444.
  • Bauzon, M., Hermiston, T.W. Exploiting diversity: genetic approaches to creating highly potent and efficacious oncolytic viruses. Curr. Opin. Mol. Ther. 2008, 10, 350–355.
  • Harrington, K.J., Melcher, A., Vassaux, G., Pandha, H.S., Vile, R.G. Exploiting synergies between radiation and oncolytic viruses. Curr. Opin. Mol. Ther. 2008, 10, 362–370.
  • Guo, Z.S., Thorne, S.H., Bartlett, D.L. Oncolytic virotherapy: molecular targets in tumor-selective replication and carrier cell-mediated delivery of oncolytic viruses. Biochim. Biophys. Acta 2008, 1785, 217–231.
  • Chang, C.M., Coville, J.L., Coquerelle, G., Gourichon, D., Oulmouden, A., Tixier-Boichard, M. Complete association between a retroviral insertion in the tyrosinase gene and the recessive white mutation in chickens. BMC Genomics 2006, 5, 7–19.
  • Chang, C.M., Furet, J.P., Coville, J.L., Coquerelle, G., Gourichon, D., Tixier-Boichard, M. Quantitative effects of an intronic retroviral insertion on the transcription of the tyrosinase gene in recessive white chickens. Anim. Genet. 2007, 38, 162–167.
  • Ikeda, T., Shibata, J., Yoshimura, K., Koito, A., Matsushita, S. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J. Infect. Dis. 2007, 195, 716–725.
  • Valk, P.J., Hol, S., Vankan, Y., Ihle, J.N., Askew, D., Jenkins, N.A., Gilbert, D.J., Copeland, N.G., de Both, N.J., Löwenberg, B., Delwel, R. The genes encoding the peripheral cannabinoid receptor and alpha-L-fucosidase are located near a newly identified common virus integration site, Evi11. J. Virol. 1997, 71, 6796–6804.
  • Baum, C., Düllmann, J., Li, Z., Fehse, B., Meyer, J., Williams, D.A., von Kalle, C. Side effects of retroviral gene transfer into hematopoietic stem cells. Blood 2003, 101, 2099–2114.
  • Mack, K.D., Jin, X., Yu, S., Wei, R., Kapp, L., Green, C., Herndier, B., Abbey, N.W., Elbaggari, A., Liu, Y., McGrath, M.S. HIV insertions within and proximal to host cell genes are a common finding in tissues containing high levels of HIV DNA and macrophage-associated p24 antigen expression. J. Acquir. Immune Defic. Syndr. 2003, 33, 308–320.
  • Themis, M., May, D., Coutelle, C., Newbold, R.F. Mutational effects of retrovirus insertion on the genome of V79 cells by an attenuated retrovirus vector: implications for gene therapy. Gene Ther. 2003, 10, 1703–1711.
  • Laufs, S., Nagy, K.Z., Giordano, F.A., Hotz-Wagenblatt, A., Zeller, W.J., Fruehauf, S. Insertion of retroviral vectors in NOD/SCID repopulating human peripheral blood progenitor cells occurs preferentially in the vicinity of transcription start regions and in introns. Mol. Ther. 2004, 10, 874–881.
  • Takakuwa, T., Luo, W.J., Ham, M.F., Sakane-Ishikawa, F., Wada, N., Aozasa, K. Integration of Epstein-Barr virus into chromosome 6q15 of Burkitt lymphoma cell line (Raji) induces loss of BACH2 expression. Am. J. Pathol. 2004, 164, 967–974.
  • Du, Y., Jenkins, N.A., Copeland, N.G. Insertional mutagenesis identifies genes that promote the immortalization of primary bone marrow progenitor cells. Blood 2005, 106, 3932–3939.
  • Kustikova, O., Fehse, B., Modlich, U., Yang, M., Düllmann, J., Kamino, K., von Neuhoff, N., Schlegelberger, B., Li, Z., Baum, C. Clonal dominance of hematopoietic stem cells triggered by retroviral gene marking. Science 2005, 308, 1171–1174.
  • Perincheri, S., Dingle, R.W., Peterson, M.L., Spear, B.T. Hereditary persistence of alpha-fetoprotein and H19 expression in liver of BALB/cJ mice is due to a retrovirus insertion in the Zhx2 gene. Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 396–401.
  • Nienhuis, A.W. Assays to evaluate the genotoxicity of retroviral vectors. Mol. Ther. 2006, 14, 459–460.
  • Nienhuis, A.W., Dunbar, C.E., Sorrentino, B.P. Genotoxicity of retroviral integration in hematopoietic cells. Mol. Ther. 2006, 13, 1031–1049.
  • Tsukahara, T., Agawa, H., Matsumoto, S., Matsuda, M., Ueno, S., Yamashita, Y., Yamada, K., Tanaka, N., Kojima, K., Takeshita, T. Murine leukemia virus vector integration favors promoter regions and regional hot spots in a human T-cell line. Biochem. Biophys. Res. Commun. 2006, 345, 1099–1107.
  • Panaro, M.A., Calvello, R., Lisi, S., Saccia, M., Mitolo, C.I., Cianciulli, A. Viral sequence integration into introns of chemokine receptor genes. Immunopharmacol. Immunotoxicol. 2009, 31, 589–594.
  • Hacein-Bey-Abina, S., Von Kalle, C., Schmidt, M., McCormack, M.P., Wulffraat, N., Leboulch, P., Lim, A., Osborne, C.S., Pawliuk, R., Morillon, E., Sorensen, R., Forster, A., Fraser, P., Cohen, J.I., de Saint Basile, G., Alexander, I., Wintergerst, U., Frebourg, T., Aurias, A., Stoppa-Lyonnet, D., Romana, S., Radford-Weiss, I., Gross, F., Valensi, F., Delabesse, E., Macintyre, E., Sigaux, F., Soulier, J., Leiva, L.E., Wissler, M., Prinz, C., Rabbitts, T.H., Le Deist, F., Fischer, A., Cavazzana-Calvo, M. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 2003, 302, 415–419.
  • Hacein-Bey-Abina, S., Garrigue, A., Wang, G.P., Soulier, J., Lim, A., Morillon, E., Clappier, E., Caccavelli, L., Delabesse, E., Beldjord, K., Asnafi, V., MacIntyre, E., Dal Cortivo, L., Radford, I., Brousse, N., Sigaux, F., Moshous, D., Hauer, J., Borkhardt, A., Belohradsky, B.H., Wintergerst, U., Velez, M.C., Leiva, L., Sorensen, R., Wulffraat, N., Blanche, S., Bushman, F.D., Fischer, A., Cavazzana-Calvo, M. Insertional oncogenesis in 4 patients after retrovirus-mediated gene therapy of SCID-X1. J. Clin. Invest. 2008, 118, 3132–3142.
  • Panaro M.A., Calvello R., Mitolo C.I., Sisto M., Cianciulli A. Evidence for endogenous retroviruses in human chemokine receptor gene introns: possible evolutionary inferences and biological roles. Immunopharmacol. Immunotoxicol. 2010 (In Press).
  • Kehrl, J.H., Hwang, I.Y., Park, C. Chemoattract receptor signaling and its role in lymphocyte motility and trafficking. Curr. Top. Microbiol. Immunol. 2009, 334, 107–127.
  • Lee, H.T., Shiao, Y.M., Wu, T.H., Chen, W.S., Hsu, Y.H., Tsai, S.F., Tsai, C.Y. Serum BLC/CXCL13 concentrations and renal expression of CXCL13/CXCR5 in patients with systemic lupus erythematosus and lupus nephritis. J. Rheumatol. 2010, 37, 45–52.
  • Singh, S., Singh, R., Singh, U.P., Rai, S.N., Novakovic, K.R., Chung, L.W., Didier, P.J., Grizzle, W.E., Lillard, J.W. Jr. Clinical and biological significance of CXCR5 expressed by prostate cancer specimens and cell lines. Int. J. Cancer 2009, 125, 2288–2295.
  • Griffiths A.J.F., Miller J.H., Suzuki D.T., Lewontin R.C., Gelbart W.M. An Introduction to Genetic Analysis. 7th edn. New York: W. H. Freeman and Company, 2000.
  • Pennisi, E. Evolution. Jumping genes hop into the evolutionary limelight. Science 2007, 317, 894–895.
  • Woolfe, A., Goodson, M., Goode, D.K., Snell, P., McEwen, G.K., Vavouri, T., Smith, S.F., North, P., Callaway, H., Kelly, K., Walter, K., Abnizova, I., Gilks, W., Edwards, Y.J., Cooke, J.E., Elgar, G. Highly conserved non-coding sequences are associated with vertebrate development. PLoS Biol. 2005, 3, e7.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.