Protective effects of quercetin and chrysin against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) induced oxidative stress, body wasting and altered cytokine productions in rats

References

• Guo, X., Longnecker, M.P., Michalek, J.E. Relation of serum tetrachlorodibenzo-p-dioxin concentration to diet among veterans in the Air Force Health Study with background-level exposure. J. Toxicol. Environ. Health Part A 2001, 63, 159–172.
   PubMed Web of Science ®Google Scholar
• Hassoun, E.A., Vodhanel, J., Abushaban, A. The modulatory effects of ellagic acid and vitamin E succinate on TCDD-induced oxidative stress in different brain regions of rats after subchronic exposure. J. Biochem. Mol. Toxicol. 2004;18:96–203.
   Web of Science ®Google Scholar
• Ciftci, O., Tanyildizi, S., Godekmerdan, A. Protective effect of curcumin on immune system and body weight gain on rats intoxicated with 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD). Immunopharmacol. Immunotoxicol. 2010, 32, 99–104.
   PubMed Web of Science ®Google Scholar
• Nishiumi, S., Yoshida, M., Azuma, T., Yoshida, K., Ashida, H. 2,3,7,8-tetrachlorodibenzo-p-dioxin impairs an insulin signaling pathway through the induction of tumor necrosis factor-α in adipocytes. Toxicol. Sci. 2010, 115, 482–491.
   PubMed Web of Science ®Google Scholar
• Lee, C.C., Yao, Y.J., Chen, H.L., Guo, Y.L., Su, H.J. Fatty liver and hepatic function for residents with markedly high serum PCDD/Fs levels in Taiwan. J. Toxicol. Environ. Health Part A 2006, 69, 367–380.
   PubMed Web of Science ®Google Scholar
• Ishida, T., Taketoh, J., Nakatsune, E., Kan-o, S., Naito, E., Takeda, S., Mutoh, J., Ishii, Y., Yamada, H. Curcumin Anticipates the Suppressed Body Weight Gain with 2,3,7,8-Tetrachlorodibenzo-p-Dioxin in Mice. J. Health Sci.2004;50:474–482.
   Google Scholar
• Hassoun, E.A., Al-Ghafri, M., Abushaban, A. The role of antioxidant enzymes in TCDD-induced oxidative stress in various brain regions of rats after subchronic exposure. Free Radic. Biol. Med. 2003, 35, 1028–1036.
   PubMed Web of Science ®Google Scholar
• Bischoff, S.C. Quercetin: potentials in the prevention and therapy of disease. Curr. Opin. Clin. Nutr. Metab. Care 2008, 11, 733–740.
   PubMed Web of Science ®Google Scholar
• Fu, B., Xue, J., Li, Z., Shi, X., Jiang, B.H., Fang, J. Chrysin inhibits expression of hypoxia-inducible factor-1α through reducing hypoxia-inducible factor-1α stability and inhibiting its protein synthesis. Mol. Cancer Ther. 2007, 6, 220–226.
   PubMed Web of Science ®Google Scholar
• Wang, X., Morris, M.E. Effects of the flavonoid chrysin on nitrofurantoin pharmacokinetics in rats: potential involvement of ABCG2. Drug Metab. Dispos. 2007, 35, 268–274.
   PubMed Web of Science ®Google Scholar
• Muthukumaran, S., Sudheer, A.R., Menon, V.P., Nalini, N. Protective effect of quercetin on nicotine-induced prooxidant and antioxidant imbalance and DNA damage in Wistar rats. Toxicology 2008, 243, 207–215.
   PubMed Web of Science ®Google Scholar
• Azuma, K., Ippoushi, K., Terao, J. Evaluation of tolerable levels of dietary quercetin for exerting its antioxidative effect in high cholesterol-fed rats. Food Chem. Toxicol. 2010, 48, 1117–1122.
   PubMed Web of Science ®Google Scholar
• Latchoumycandane, C., Mathur, P.P. Effects of vitamin E on reactive oxygen species-mediated 2,3,7,8-tetrachlorodi-benzo-p-dioxin toxicity in rat testis. J. Appl. Toxicol. 2002, 22, 345–351.
   PubMed Web of Science ®Google Scholar
• Yagi, K. Simple assay for the level of total lipid peroxides in serum or plasma. Methods Mol. Biol. 1998, 108, 101–106.
   PubMedGoogle Scholar
• Fan, F., Yan, B., Wood, G., Viluksela, M., Rozman, K.K. Cytokines (IL-1beta and TNF-α) in relation to biochemical and immunological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rats. Toxicology 1997, 116, 9–16.
   PubMed Web of Science ®Google Scholar
• Fan, F., Yan, B., Wood, G., Viluksela, M., Rozman, K.K. Cytokines (IL-1beta and TNF-α) in relation to biochemical and immunological effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in rats. Toxicology 1997, 116, 9–16.
   PubMed Web of Science ®Google Scholar
• Kerkvliet, N.I. Recent advances in understanding the mechanisms of TCDD immunotoxicity. Int. Immunopharmacol. 2002, 2, 277–291.
   PubMed Web of Science ®Google Scholar
• Park, H.H., Lee, S., Son, H.Y., Park, S.B., Kim, M.S., Choi, E.J., Singh, T.S., Ha, J.H., Lee, M.G., Kim, J.E., Hyun, M.C., Kwon, T.K., Kim, Y.H., Kim, S.H. Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cells. Arch. Pharm. Res. 2008, 31, 1303–1311.
   PubMed Web of Science ®Google Scholar
• Pang, J.L., Ricupero, D.A., Huang, S., Fatma, N., Singh, D.P., Romero, J.R., Chattopadhyay, N. Differential activity of kaempferol and quercetin in attenuating tumor necrosis factor receptor family signaling in bone cells. Biochem. Pharmacol. 2006, 71, 818–826.
   PubMed Web of Science ®Google Scholar
• Murray, H.W. Interferon-γ and host antimicrobial defense: current and future clinical applications. Am. J. Med. 1994, 97, 459–467.
   PubMed Web of Science ®Google Scholar
• Oh, E., Lee, E., Im, H., Kang, H.S., Jung, W.W., Won, N.H., Kim, E.M., Sul, D. Evaluation of immuno- and reproductive toxicities and association between immunotoxicological and genotoxicological parameters in waste incineration workers. Toxicology 2005, 210, 65–80.
   PubMed Web of Science ®Google Scholar
• Nohara, K., Fujimaki, H., Tsukumo, S., Inouye, K., Sone, H., Tohyama, C. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on T cell-derived cytokine production in ovalbumin (OVA)-immunized C57Bl/6 mice. Toxicology 2002, 172, 49–58.
   PubMed Web of Science ®Google Scholar
• Kim, E.K., Kwon, K.B., Song, M.,Y., Han, M.J., Lee, J.H., Lee, Y.R., Lee, J.H., Ryu, D.G., Park, B.H., Park, J.W. Flavonoids protect against cytokine-induced pancreatic β-cell damage through suppression of nuclear factor κ B activation. Pancreas 2007;35:1–9.
   PubMed Web of Science ®Google Scholar
• Chen, H.L., Hsu, C.Y., Hung, D.Z., Hu, M.L. Lipid peroxidation and antioxidant status in workers exposed to PCDD/Fs of metal recovery plants. Sci. Total Environ. 2006, 372, 12–19.
   PubMed Web of Science ®Google Scholar
• Yoshida, R., Ogawa, Y., Mori, I., Nakata, A., Wang, R., Ueno, S., Shioji, I., Hisanaga, N. Associations between oxidative stress levels and total duration of engagement in jobs with exposure to fly ash among workers at municipal solid waste incinerators. Mutagenesis 2003, 18, 533–537.
   PubMed Web of Science ®Google Scholar
• Mimura, J., Fujii-Kuriyama, Y. Functional role of AhR in the expression of toxic effects by TCDD. Biochim. Biophys. Acta 2003, 1619, 263–268.
   PubMed Web of Science ®Google Scholar
• Alsharif, N.Z., Grandjean, C.J., Murray, W.J., Stohs, S.J. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD)-induced decrease in the fluidity of rat liver membranes. Xenobiotica. 1990, 20, 979–988.
   PubMed Web of Science ®Google Scholar
• Kahraman, A., Inal, M.E. Protective effects of quercetin on ultraviolet A light-induced oxidative stress in the blood of rat. J. Appl. Toxicol. 2002, 22, 303–309.
   PubMed Web of Science ®Google Scholar
• Pushpavalli, G., Kalaiarasi, P., Veeramani, C., Pugalendi, K.V. Effect of chrysin on hepatoprotective and antioxidant status in D-galactosamine-induced hepatitis in rats. Eur. J. Pharmacol. 2010, 631, 36–41.
   PubMed Web of Science ®Google Scholar
• Moskaug, J.O., Carlsen, H., Myhrstad, M., Blomhoff, R. Molecular imaging of the biological effects of quercetin and quercetin-rich foods. Mech. Ageing Dev. 2004;125:315–324.
   PubMed Web of Science ®Google Scholar
• Rier, S.E., Coe, C.L., Lemieux, A.M., Martin, D.C., Morris, R., Lucier, G.W., Clark, G.C. Increased tumor necrosis factor-α production by peripheral blood leukocytes from TCDD-exposed rhesus monkeys. Toxicol. Sci. 2001, 60, 327–337.
   PubMed Web of Science ®Google Scholar
• Kern, P.A., Fishman, R.B., Song, W., Brown, A.D., Fonseca, V. The effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on oxidative enzymes in adipocytes and liver. Toxicology 2002, 171, 117–125.
   PubMed Web of Science ®Google Scholar