254
Views
31
CrossRef citations to date
0
Altmetric
Original Article

Suppression of inflammatory responses after onset of collagen-induced arthritis in mice by oral administration of the Citrus flavanone naringin

, , &
Pages 723-729 | Received 05 Jan 2011, Accepted 15 Feb 2011, Published online: 11 Apr 2011

References

  • Kumazawa, Y., Kawaguchi, K., Takimoto, H. Immunomodulating effects of flavonoids on acute and chronic inflammatory responses caused by tumor necrosis factor-α. Curr Pharm Des 2006, 12, 427–429.
  • Abad, M.J., Bermejo, P., Alvarez, M., Guerra, J.A., Silván, A.M., Villar, A.M. Flavonoids and a sesquiterpene lactone from Tanacetum microphyllum inhibit anti-inflammatory mediators in LPS-stimulated mouse peritoneal macrophages. Planta Med 2004, 70, 34–38.
  • Ban, H.S., Suzuki, K., Lim, S.S., Jung, S.H., Lee, S., Ji, J., Lee, H.S., Lee, Y.S., Shin, K.H., Ohuchi, K. Inhibition of lipopolysaccharide-induced expression of inducible nitric oxide synthase and tumor necrosis factor-alpha by 2′-hydroxychalcone derivatives in RAW 264.7 cells. Biochem Pharmacol 2004, 67, 1549–1557.
  • Chiu, J.H., Lay, I.S., Su, M.Y., Chiu, H.L., Chiu, A.C., Lui, W.Y., Wu, C.W. Tumor necrosis factor-producing activity of wogonin in RAW 264.7 murine macrophage cell line. Planta Med 2002, 68, 1036–1039.
  • Fang, S.H., Houm, Y.C., Chang, W.C., Hsiu, S.L., Chao, P.D., Chiang, B.L. Morin sulfates/glucuronides exert anti-inflammatory activity on activated macrophages and decrease the incidence of septic shock. Life Sci 2003, 74, 743–756.
  • Gottstein, N., Ewins, B.A., Eccleston, C., Hubbard, G.P., Kavanagh, I.C., Minihane, A.M., Weinberg, P.D., Rimbach, G. Effect of genistein and daidzein on platelet aggregation and monocyte and endothelial function. Br J Nutr 2003, 89, 607–616.
  • Herath, H.M., Takano-Ishikawa, Y., Yamaki, K. Inhibitory effect of some flavonoids on tumor necrosis factor-alpha production in lipopolysaccharide-stimulated mouse macrophage cell line J774.1. J Med Food 2003, 6, 365–370.
  • Ichikawa, D., Matsui, A., Imai, M., Sonoda, Y., Kasahara, T. Effect of various catechins on the IL-12p40 production by murine peritoneal macrophages and a macrophage cell line, J774.1. Biol Pharm Bull 2004, 27, 1353–1358.
  • Lin, N., Sato, T., Takayama, Y., Mimaki, Y., Sashida, Y., Yano, M., Ito, A. Novel anti-inflammatory actions of nobiletin, a Citrus polymethoxy flavonoid, on human synovial fibroblasts and mouse macrophages. Biochem Pharmacol 2003, 65, 2065–2071.
  • Rao, Y.K., Fang, S.H., Tzeng, Y.M. Inhibitory effects of the flavonoids isolated from Waltheria indica on the production of NO, TNF-α and IL-12 in activated macrophages. Biol Pharm Bull 2005, 28, 912–915.
  • Smolinski, A.T., Pestka, J.J. Modulation of lipopolysaccharide-induced proinflammatory cytokine production in vitro and in vivo by the herbal constituents apigenin (chamomile), ginsenoside Rb(1) (ginseng) and parthenolide (feverfew). Food Chem Toxicol 2003, 41, 1381–1390.
  • Ueda, H., Yamazaki, C., Yamazaki, M. A hydroxyl group of flavonoids affects oral anti-inflammatory activity and inhibition of systemic tumor necrosis factor-α production. Biosci Biotechnol Biochem 2004, 68, 119–125.
  • Xagorari, A., Roussos, C., Papapetropoulos, A. Inhibition of LPS-stimulated pathways in macrophages by the flavonoid luteolin. Br J Pharmacol 2002, 136, 1058–1064.
  • Kawaguchi, K., Kikuchi, S., Hasegawa, H., Maruyama, H., Morita, H., Kumazawa, Y. Suppression of lipopolysaccharide-induced tumor necrosis factor-release and liver injury in mice by naringin. Eur J Pharmacol 1999, 368, 245–250.
  • Kawaguchi, K., Kikuchi, S., Hasunuma, R., Maruyama, H., Ryll, R., Kumazawa, Y. Suppression of infection-induced endotoxin shock in mice by a Citrus flavanone naringin. Planta Med 2004, 70, 17–22.
  • Klareskog, L., McDevitt, H. Rheumatoid arthritis and its animal models: The role of TNF-α and the possible absence of specific immune reactions. Curr Opin Immunol 1999, 11, 657–662.
  • Mikuls, T.R., Weaver, A.L. Lessons learned in the use of tumor necrosis factor-α inhibitors in the treatment of rheumatoid arthritis. Curr Rheumatol Rep 2003, 5, 270–277.
  • Taylor, P.C. Anti-TNFα therapy for rheumatoid arthritis: An update. Internat Med 2003, 42, 15–20.
  • Kawaguchi, K., Maruyama, H., Kometani, T., Kumazawa, Y. Suppression of collagen-induced arthritis by oral administration of the Citrus flavonoid hesperidin. Planta Med 2006, 72, 477–479.
  • Stenman, M., Ainola, M., Valmu, L., Bjartell, A., Ma, G., Stenman, U.H., Sorsa, T., Luukkainen, R., Konttinen, Y.T. Trypsin-2 degrades human type II collagen and is expressed and activated in mesenchymally transformed rheumatoid arthritis synovitis tissue. Am J Pathol 2005, 167, 1119–1124.
  • af Klint, E., Grundtman, C., Engström, M., Catrina, A.I., Makrygiannakis, D., Klareskog, L., Andersson, U., Ulfgren, A.K. Intraarticular glucocorticoid treatment reduces inflammation in synovial cell infiltrations more efficiently than in synovial blood vessels. Arthritis Rheum 2005, 52, 3880–3889.
  • Kokkola, R., Li, J., Sundberg, E., Aveberger, A.C., Palmblad, K., Yang, H., Tracey, K.J., Andersson, U., Harris, H.E. Successful treatment of collagen-induced arthritis in mice and rats by targeting extracellular high mobility group box chromosomal protein 1 activity. Arthritis Rheum 2003, 48, 2052–2058.
  • Taniguchi, N., Kawahara, K., Yone, K., Hashiguchi, T., Yamakuchi, M., Goto, M., Inoue, K., Yamada, S., Ijiri, K., Matsunaga, S., Nakajima, T., Komiya, S., Maruyama, I. High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine. Arthritis Rheum 2003, 48, 971–981.
  • Hare, J.T., Elliott, D.P. Grapefruit juice and potential drug interactions. Consult Pharm 2003, 18, 466–472.
  • Grenier, J., Fradette, C., Morelli, G., Merritt, G.J., Vranderick, M., Ducharme, M.P. Pomelo juice, but not cranberry juice, affects the pharmacokinetics of cyclosporine in humans. Clin Pharmacol Ther 2006, 79, 255–262.
  • Culm-Merdek, K.E., von Moltke, L.L., Gan, L., Horan, K.A., Reynolds, R., Harmatz, J.S., Court, M.H., Greenblatt, D.J. Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans: Comparison with ritonavir. Clin Pharmacol Ther 2006, 79, 243–254.
  • Deleuran, B.W., Chu, C.Q., Field, M., Brennan, F.M., Mitchell, T., Feldmann, M., Maini, R.N. Localization of tumor necrosis factor receptors in the synovial tissue and cartilage-pannus junction in patients with rheumatoid arthritis. Implications for local actions of tumor necrosis factor alpha. Arthritis Rheum 1992, 35, 1170–1178.
  • Park, J.S., Svetkauskaite, D., He, Q., Kim, J.Y., Strassheim, D., Ishizaka, A., Abraham, E. Involvement of toll-like receptors 2 and 4 in cellular activation by high mobility group box 1 protein. J Biol Chem 2004, 279, 7370–7377.
  • Andersson, U., Wang, H., Palmblad, K., Aveberger, A.C., Bloom, O., Erlandsson-Harris, H., Janson, A., Kokkola, R., Zhang, M., Yang, H., Tracey, K.J. High mobility group 1 protein (HMG-1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med 2000, 192, 565–570.
  • Kanaze, F.I., Bounartzi, M.I., Georgarakis, M., Niopas, I. Pharmacokinetics of the Citrus flavanone aglycones hesperetin and naringenin after single oral administration in human subjects. Eur J Clin Nutr 2007, 61, 472–477.
  • Kometani, T., Nishimura, T., Nakae, T., Takii, H., Okada, S. Synthesis of neohesperidin glycosides and naringin glycosides by cyclodextrin glucanotransferase from an alkalophilic Bacillus species. Biosci Biotechnol Biochem 1996, 60, 645–649.
  • Kim, M., Kometani, T., Okada, S., Shimuzu, M. Permeation of hesperidin glycosides across Caco-2 cell monolayer via the paracellular pathway. Biosci Biotechnol Biochem 1999, 63, 2183–2188.
  • Shimoi, K., Saka, N., Nozawa, R., Sato, M., Amano, I., Nakayama, T., Kinae, N. Deglucuronidation of a flavonoid, luteolin monoglucuronide, during inflammation. Drug Metab Dispos 2001, 29, 1521–1524.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.