In vitro expansion of human γδ and CD56⁺ T-cells by Aspergillus-antigen loaded fast dendritic cells in the presence of exogenous interleukin-12

References

• Falini, B., Flenghi, L., Pileri, S., Pelicci, P., Fagioli, M., Martelli, M.F., Moretta, L., Ciccone, E. Distribution of T cells bearing different forms of the T cell receptor gamma/delta in normal and pathological human tissues. J Immunol 1989, 143, 2480–2488.
   PubMed Web of Science ®Google Scholar
• Knight, A., Madrigal, A.J., Grace, S., Sivakumaran, J., Kottaridis, P., Mackinnon, S., Travers, P.J., Lowdell, M.W. The role of Vd2-negative ?d T cells during cytomegalovirus reactivation in recipients of allogeneic stem cell transplantation. Blood 2010, 116, 2164–2172.
   PubMed Web of Science ®Google Scholar
• Lopez, R.D. Human gammadelta-T cells in adoptive immunotherapy of malignant and infectious diseases. Immunol Res 2002, 26, 207–221.
   PubMed Web of Science ®Google Scholar
• Wallace, M., Bartz, S.R., Chang, W.L., Mackenzie, D.A., Pauza, C.D., Malkovsky, M. Gamma delta T lymphocyte responses to HIV. Clin Exp Immunol 1996, 103, 177–184.
   PubMed Web of Science ®Google Scholar
• Boismenu, R., Havran, W.L. Modulation of epithelial cell growth by intraepithelial gamma delta T cells. Science 1994, 266, 1253–1255.
   PubMed Web of Science ®Google Scholar
• Kawanishi, Y., Passweg, J., Drobyski, W.R., Rowlings, P., Cook-Craig, A., Casper, J., Pietryga, D., Garbrecht, F., Camitta, B., Horowitz, M., Juckett, M., Margolis, D., Flomenberg, N., Keever-Taylor, C.A. Effect of T cell subset dose on outcome of T cell-depleted bone marrow transplantation. Bone Marrow Transplant 1997, 19, 1069–1077.
   PubMed Web of Science ®Google Scholar
• Ericsson, P.O., Hansson, J., Widegren, B., Dohlsten, M., Sjögren, H.O., Hedlund, G. In vivo induction of gamma/delta T cells with highly potent and selective anti-tumor cytotoxicity. Eur J Immunol 1991, 21, 2797–2802.
   PubMed Web of Science ®Google Scholar
• Fisch, P., Malkovsky, M., Kovats, S., Sturm, E., Braakman, E., Klein, B.S., Voss, S.D., Morrissey, L.W., DeMars, R., Welch, W.J. Recognition by human V gamma 9/V delta 2 T cells of a GroEL homolog on Daudi Burkitt’s lymphoma cells. Science 1990, 250, 1269–1273.
   PubMed Web of Science ®Google Scholar
• Girardi, M., Oppenheim, D.E., Steele, C.R., Lewis, J.M., Glusac, E., Filler, R., Hobby, P., Sutton, B., Tigelaar, R.E., Hayday, A.C. Regulation of cutaneous malignancy by gammadelta T cells. Science 2001, 294, 605–609.
   PubMed Web of Science ®Google Scholar
• Kaminski, M.J., Cruz, P.D. Jr, Bergstresser, P.R., Takashima, A. Killing of skin-derived tumor cells by mouse dendritic epidermal T-cells. Cancer Res 1993, 53, 4014–4019.
   PubMed Web of Science ®Google Scholar
• Nanno, M., Seki, H., Mathioudakis, G., Suzuki, R., Itoh, K., Ioannides, C.G., Suzuki, S., Chen, P.F., Platsoucas, C.D. Gamma/delta T cell antigen receptors expressed on tumor-infiltrating lymphocytes from patients with solid tumors. Eur J Immunol 1992, 22, 679–687.
   PubMed Web of Science ®Google Scholar
• Alexander, A.A., Maniar, A., Cummings, J.S., Hebbeler, A.M., Schulze, D.H., Gastman, B.R., Pauza, C.D., Strome, S.E., Chapoval, A.I. Isopentenyl pyrophosphate-activated CD56+ {gamma}{delta} T lymphocytes display potent antitumor activity toward human squamous cell carcinoma. Clin Cancer Res 2008, 14, 4232–4240.
   PubMed Web of Science ®Google Scholar
• Janssen, O., Wesselborg, S., Heckl-Ostreicher, B., Pechhold, K., Bender, A., Schondelmaier, S., Moldenhauer, G., Kabelitz, D. T cell receptor/CD3-signaling induces death by apoptosis in human T cell receptor gamma delta + T cells. J Immunol 1991, 146, 35–39.
   PubMed Web of Science ®Google Scholar
• Lopez, R.D., Xu, S., Guo, B., Negrin, R.S., Waller, E.K. CD2-mediated IL-12-dependent signals render human gamma delta-T cells resistant to mitogen-induced apoptosis, permitting the large-scale ex vivo expansion of functionally distinct lymphocytes: implications for the development of adoptive immunotherapy strategies. Blood 2000, 96, 3827–3837.
   PubMed Web of Science ®Google Scholar
• Steinman, R.M. Lasker Basic Medical Research Award. Dendritic cells: versatile controllers of the immune system. Nat Med 2007, 13, 1155–1159.
   Google Scholar
• Gruenbacher, G., Gander, H., Rahm, A., Nussbaumer, W., Romani, N., Thurnher, M. CD56+ human blood dendritic cells effectively promote TH1-type gammadelta T-cell responses. Blood 2009, 114, 4422–4431.
   Google Scholar
• Münz, C., Steinman, R.M., Fujii, S. Dendritic cell maturation by innate lymphocytes: coordinated stimulation of innate and adaptive immunity. J Exp Med 2005, 202, 203–207.
   PubMed Web of Science ®Google Scholar
• Meraviglia, S., Caccamo, N., Salerno, A., Sireci, G., Dieli, F. Partial and ineffective activation of V gamma 9V delta 2 T cells by Mycobacterium tuberculosis-infected dendritic cells. J Immunol 2010, 185, 1770–1776.
   Google Scholar
• Marr, K.A., Patterson, T., Denning, D. Aspergillosis. Pathogenesis, clinical manifestations, and therapy. Infect Dis Clin North Am 2002, 16, 875–94, vi.
   PubMed Web of Science ®Google Scholar
• Hebart, H., Bollinger, C., Fisch, P., Sarfati, J., Meisner, C., Baur, M., Loeffler, J., Monod, M., Latgé, J.P., Einsele, H. Analysis of T-cell responses to Aspergillus fumigatus antigens in healthy individuals and patients with hematologic malignancies. Blood 2002, 100, 4521–4528.
   PubMed Web of Science ®Google Scholar
• Denning, D.W. Invasive aspergillosis. Clin Infect Dis 1998, 26, 781–803; quiz 804.
   PubMed Web of Science ®Google Scholar
• Ramadan, G. The proliferative response of T cells to Aspergillus antigen requires prior presentation on dendritic cells. Egypt J Immunol 2004, 11, 47–58.
   PubMedGoogle Scholar
• Ramadan, G. Generation of Aspergillus-specific T lymphocytes with cytotoxic activity. Egypt J Immunol 2004, 11, 59–70.
   PubMedGoogle Scholar
• Emtage, P.C., Clarke, D., Gonzalo-Daganzo, R., Junghans, R.P., Gonzalo-Dagonzo, R. Generating potent Th1/Tc1 T cell adoptive immunotherapy doses using human IL-12: Harnessing the immunomodulatory potential of IL-12 without the in vivo-associated toxicity. J Immunother 2003, 26, 97–106.
   PubMed Web of Science ®Google Scholar
• Xu, S., Koski, G.K., Faries, M., Bedrosian, I., Mick, R., Maeurer, M., Cheever, M.A., Cohen, P.A., Czerniecki, B.J. Rapid high efficiency sensitization of CD8+ T cells to tumor antigens by dendritic cells leads to enhanced functional avidity and direct tumor recognition through an IL-12-dependent mechanism. J Immunol 2003, 171, 2251–2261.
   PubMed Web of Science ®Google Scholar
• Ramadan, G., Konings, S., Kurup, V.P., Keever-Taylor, C.A. Generation of Aspergillus- and CMV- specific T-cell responses using autologous fast DC. Cytotherapy 2004, 6, 223–234.
   PubMed Web of Science ®Google Scholar
• Ramadan, G. Epstein-Barr virus-transformed B-cells as efficient antigen presenting cells to propagate Aspergillus-specific cytotoxic T-lymphocytes. Egypt J Immunol 2008, 15, 145–157.
   PubMedGoogle Scholar
• Kurup, V.P., Xia, J.Q., Rickaby, D.A., Dawson, C.A., Choi, H., Fink, J.N. Aspergillus fumigatus antigen exposure results in pulmonary airway resistance in wild-type but not in IL-4 knockout mice. Clin Immunol 1999, 90, 404–410.
   PubMed Web of Science ®Google Scholar
• Bauer, S., Groh, V., Wu, J., Steinle, A., Phillips, J.H., Lanier, L.L., Spies, T. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 1999, 285, 727–729.
   PubMed Web of Science ®Google Scholar
• Griffith, E., Ramsburg, E., Hayday, A. Recognition by human gut gamma delta cells of stress inducible major histocompatibility molecules on enterocytes. Gut 1998, 43, 166–167.
   PubMed Web of Science ®Google Scholar
• Steinle, A., Groh, V., Spies, T. Diversification, expression, and gamma delta T cell recognition of evolutionarily distant members of the MIC family of major histocompatibility complex class I-related molecules. Proc Natl Acad Sci USA 1998, 95, 12510–12515.
   PubMed Web of Science ®Google Scholar
• Kurup, V.P., Grunig, G. Animal models of allergic bronchopulmonary aspergillosis. Mycopathologia 2002, 153, 165–177.
   PubMed Web of Science ®Google Scholar
• Guo, B.L., Hollmig, K.A., Lopez, R.D. Down-regulation of IL-2 receptor alpha (CD25) characterizes human gammadelta-T cells rendered resistant to apoptosis after CD2 engagement in the presence of IL-12. Cancer Immunol Immunother 2002, 50, 625–637.
   PubMed Web of Science ®Google Scholar
• Grabstein, K.H., Eisenman, J., Shanebeck, K., Rauch, C., Srinivasan, S., Fung, V., Beers, C., Richardson, J., Schoenborn, M.A., Ahdieh, M. Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor. Science 1994, 264, 965–968.
   PubMed Web of Science ®Google Scholar
• Mattei, F., Schiavoni, G., Belardelli, F., Tough, D.F. IL-15 is expressed by dendritic cells in response to type I IFN, double-stranded RNA, or lipopolysaccharide and promotes dendritic cell activation. J Immunol 2001, 167, 1179–1187.
   PubMed Web of Science ®Google Scholar
• Pullarkat, V., Lau, R., Lee, S.M., Bender, J.G., Weber, J.S. Large-scale monocyte enrichment coupled with a closed culture system for the generation of human dendritic cells. J Immunol Methods 2002, 267, 173–183.
   PubMed Web of Science ®Google Scholar
• Braedel, S., Radsak, M., Einsele, H., Latgé, J.P., Michan, A., Loeffler, J., Haddad, Z., Grigoleit, U., Schild, H., Hebart, H. Aspergillus fumigatus antigens activate innate immune cells via toll-like receptors 2 and 4. Br J Haematol 2004, 125, 392–399.
   PubMed Web of Science ®Google Scholar
• Young, M.R. Protective mechanisms of head and neck squamous cell carcinomas from immune assault. Head Neck 2006, 28, 462–470.
   PubMed Web of Science ®Google Scholar
• Verneris, M.R., Kornacker, M., Mailänder, V., Negrin, R.S. Resistance of ex vivo expanded CD3+CD56+ T cells to Fas-mediated apoptosis. Cancer Immunol Immunother 2000, 49, 335–345.
   PubMed Web of Science ®Google Scholar