Estrogen inhibits apoptosis and promotes CC motif chemokine ligand 13 expression on synovial fibroblasts in rheumatoid arthritis

References

• Szekanecz, Z., Gáspár, L., Koch, A.E. Angiogenesis in rheumatoid arthritis. Front Biosci 2005, 10, 1739–1753.
   PubMedGoogle Scholar
• Gleicher, N., Barad, D.H. Gender as risk factor for autoimmune diseases. J Autoimmun 2007, 28, 1–6.
   PubMed Web of Science ®Google Scholar
• Masi, A.T. Sex hormones and rheumatoid arthritis: cause or effect relationships in a complex pathophysiology? Clin Exp Rheumatol 1995, 13, 227–240.
   PubMed Web of Science ®Google Scholar
• Julkunen, H. Hormone replacement therapy in women with rheumatic diseases. Scand J Rheumatol 2000, 29, 146–153.
   PubMed Web of Science ®Google Scholar
• Kanik, K.S., Wilder, R.L. Hormonal alterations in rheumatoid arthritis, including the effects of pregnancy. Rheum Dis Clin North Am 2000, 26, 805–823.
   PubMed Web of Science ®Google Scholar
• Cutolo, M., Lahita, R.G. Estrogens and arthritis. Rheum Dis Clin North Am 2005, 31, 19–27, vii.
   Google Scholar
• Kawasaki, T., Ushiyama, T., Inoue, K., Hukuda, S. Effects of estrogen on interleukin-6 production in rheumatoid fibroblast-like synoviocytes. Clin Exp Rheumatol 2000, 18, 743–745.
   PubMed Web of Science ®Google Scholar
• Itoh, Y., Hayashi, H., Miyazawa, K., Kojima, S., Akahoshi, T., Onozaki, K. 17beta-estradiol induces IL-1alpha gene expression in rheumatoid fibroblast-like synovial cells through estrogen receptor alpha (ERalpha) and augmentation of transcriptional activity of Sp1 by dissociating histone deacetylase 2 from ERalpha. J Immunol 2007, 178, 3059–3066.
   PubMed Web of Science ®Google Scholar
• Carlsten, H. Immune responses and bone loss: the estrogen connection. Immunol Rev 2005, 208, 194–206.
   PubMedGoogle Scholar
• Nilsson, B.O. Modulation of the inflammatory response by estrogens with focus on the endothelium and its interactions with leukocytes. Inflamm Res 2007, 56, 269–273.
   PubMedGoogle Scholar
• Cutolo, M., Sulli, A., Capellino, S., Villaggio, B., Montagna, P., Seriolo, B., Straub, R.H. Sex hormones influence on the immune system: basic and clinical aspects in autoimmunity. Lupus 2004, 13, 635–638.
   PubMed Web of Science ®Google Scholar
• Castagnetta, L.A., Carruba, G., Granata, O.M., Stefano, R., Miele, M., Schmidt, M., Cutolo, M., Straub, R.H. Increased estrogen formation and estrogen to androgen ratio in the synovial fluid of patients with rheumatoid arthritis. J Rheumatol 2003, 30, 2597–2605.
   PubMed Web of Science ®Google Scholar
• Marino, M., Acconcia, F., Bresciani, F., Weisz, A., Trentalance, A. Distinct nongenomic signal transduction pathways controlled by 17beta-estradiol regulate DNA synthesis and cyclin D(1) gene transcription in HepG2 cells. Mol Biol Cell 2002, 13, 3720–3729.
   PubMed Web of Science ®Google Scholar
• Iwamoto, T., Okamoto, H., Iikuni, N., Takeuchi, M., Toyama, Y., Tomatsu, T., Kamatani, N., Momohara, S. Monocyte chemoattractant protein-4 (MCP-4)/CCL13 is highly expressed in cartilage from patients with rheumatoid arthritis. Rheumatology (Oxford) 2006, 45, 421–424.
   PubMedGoogle Scholar
• Iwamoto, T., Okamoto, H., Kobayashi, S., Ikari, K., Toyama, Y., Tomatsu, T., Kamatani, N., Momohara, S. A role of monocyte chemoattractant protein-4 (MCP-4)/CCL13 from chondrocytes in rheumatoid arthritis. FEBS J 2007, 274, 4904–4912.
   PubMedGoogle Scholar
• Hintzen, C., Quaiser, S., Pap, T., Heinrich, P.C., Hermanns, H.M. Induction of CCL13 expression in synovial fibroblasts highlights a significant role of oncostatin M in rheumatoid arthritis. Arthritis Rheum 2009, 60, 1932–1943.
   PubMed Web of Science ®Google Scholar
• Schett, G., Tohidast-Akrad, M., Smolen, J.S., Schmid, B.J., Steiner, C.W., Bitzan, P., Zenz, P., Redlich, K., Xu, Q., Steiner, G. Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis. Arthritis Rheum 2000, 43, 2501–2512.
   PubMed Web of Science ®Google Scholar
• Thiel, M.J., Schaefer, C.J., Lesch, M.E., Mobley, J.L., Dudley, D.T., Tecle, H., Barrett, S.D., Schrier, D.J., Flory, C.M. Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: potential proinflammatory mechanisms. Arthritis Rheum 2007, 56, 3347–3357.
   PubMedGoogle Scholar
• Acconcia, F., Ascenzi, P., Bocedi, A., Spisni, E., Tomasi, V., Trentalance, A., Visca, P., Marino, M. Palmitoylation-dependent estrogen receptor alpha membrane localization: regulation by 17beta-estradiol. Mol Biol Cell 2005, 16, 231–237.
   PubMed Web of Science ®Google Scholar
• Galluzzo, P., Caiazza, F., Moreno, S., Marino, M. Role of ERbeta palmitoylation in the inhibition of human colon cancer cell proliferation. Endocr Relat Cancer 2007, 14, 153–167.
   Google Scholar
• Acconcia, F., Totta, P., Ogawa, S., Cardillo, I., Inoue, S., Leone, S., Trentalance, A., Muramatsu, M., Marino, M. Survival versus apoptotic 17beta-estradiol effect: role of ER alpha and ER beta activated non-genomic signaling. J Cell Physiol 2005, 203, 193–201.
   PubMed Web of Science ®Google Scholar
• Ronda, A.C., Vasconsuelo, A., Boland, R. Extracellular-regulated kinase and p38 mitogen-activated protein kinases are involved in the antiapoptotic action of 17beta-estradiol in skeletal muscle cells. J Endocrinol 2010, 206, 235–246.
   Google Scholar
• Burrage, P.S., Mix, K.S., Brinckerhoff, C.E. Matrix metalloproteinases: role in arthritis. Front Biosci 2006, 11, 529–543.
   PubMed Web of Science ®Google Scholar
• Khalkhali-Ellis, Z., Seftor, E.A., Nieva, D.R., Handa, R.J., Price, R.H. Jr, Kirschmann, D.A., Baragi, V.M., Sharma, R.V., Bhalla, R.C., Moore, T.L., Hendrix, M.J. Estrogen and progesterone regulation of human fibroblast-like synoviocyte function in vitro: implications in rheumatoid arthritis. J Rheumatol 2000, 27, 1622–1631.
   PubMed Web of Science ®Google Scholar
• Kapila, S., Wang, W., Uston, K. Matrix metalloproteinase induction by relaxin causes cartilage matrix degradation in target synovial joints. Ann N Y Acad Sci 2009, 1160, 322–328.
   PubMed Web of Science ®Google Scholar
• Szekanecz, Z., Strieter, R.M., Kunkel, S.L., Koch, A.E. Chemokines in rheumatoid arthritis. Springer Semin Immunopathol 1998, 20, 115–132.
   PubMed Web of Science ®Google Scholar
• Garcia-Zepeda, E.A., Combadiere, C., Rothenberg, M.E., Sarafi, M.N., Lavigne, F., Hamid, Q., Murphy, P.M., Luster, A.D. Human monocyte chemoattractant protein (MCP)-4 is a novel CC chemokine with activities on monocytes, eosinophils, and basophils induced in allergic and nonallergic inflammation that signals through the CC chemokine receptors (CCR)-2 and -3. J Immunol 1996, 157, 5613–5626.
   PubMed Web of Science ®Google Scholar