Intravenous IgA complexed with antigen reduces primary antibody response to the antigen and anaphylaxis upon antigen re-exposure by inhibiting Th1 and Th2 activation in mice

References

• Woof JM, Kerr MA. The function of immunoglobulin A in immunity. J Pathol 2006;208:270–282
   PubMed Web of Science ®Google Scholar
• Corthesy B. Multi-faceted functions of secretory IgA at mucosal surfaces. Front Immunol 2013;4:185
   PubMed Web of Science ®Google Scholar
• Bakema JE, van Egmond M. Immunoglobulin A: a next generation of therapeutic antibodies? mAbs 2011;3:352–361
   PubMed Web of Science ®Google Scholar
• Johansen FE, Braathen R, Brandtzaeg P. Role of J chain in secretory immunoglobulin formation. Scand J Immunol 2000;52:240–248
   PubMed Web of Science ®Google Scholar
• Wiersma EJ, Collins C, Fazel S, Shulman MJ. Structural and functional analysis of J chain-deficient IgM. J Immunol 1998;160:5979–5989
   PubMed Web of Science ®Google Scholar
• Roos A, Bouwman LH, van Gijlswijk-Janssen DJ, et al. Human IgA activates the complement system via the mannan-binding lectin pathway. J Immunol 2001;167:2861–2868
   PubMed Web of Science ®Google Scholar
• Brandtzaeg P, Prydz H. Direct evidence for an integrated function of J chain and secretory component in epithelial transport of immunoglobulins. Nature 1984;311:71–73
   PubMed Web of Science ®Google Scholar
• Murthy AK, Chaganty BK, Troutman T, et al. Mannose-containing oligosaccharides of non-specific human secretory immunoglobulin A mediate inhibition of Vibrio cholerae biofilm formation. PLoS One 2011;6:e16847
   PubMed Web of Science ®Google Scholar
• Bonner A, Almogren A, Furtado PB, et al. The nonplanar secretory IgA2 and near planar secretory IgA1 solution structures rationalize their different mucosal immune responses. J Biol Chem 2009;284:5077–5087
   PubMed Web of Science ®Google Scholar
• Crottet P, Corthesy B. Secretory component delays the conversion of secretory IgA into antigen-binding competent F(ab′)2: a possible implication for mucosal defense. J Immunol 1998;161:5445–5453
   PubMed Web of Science ®Google Scholar
• Longet S, Miled S, Lotscher M, et al. Human plasma-derived polymeric IgA and IgM antibodies associate with secretory component to yield biologically active secretory-like antibodies. J Biol Chem 2013;288:4085–4094
   PubMed Web of Science ®Google Scholar
• Herr AB, Ballister ER, Bjorkman PJ. Insights into IgA-mediated immune responses from the crystal structures of human FcαRI and its complex with IgA1-Fc. Nature 2003;423:614–620
   PubMed Web of Science ®Google Scholar
• Woof JM, Burton DR. Human antibody-Fc receptor interactions illuminated by crystal structures. Nat Rev Immunol 2004;4:89–99
   PubMed Web of Science ®Google Scholar
• Tamura S, Funato H, Hirabayashi Y, et al. Functional role of respiratory tract haemagglutinin-specific IgA antibodies in protection against influenza. Vaccine 1990;8:479–485
   PubMed Web of Science ®Google Scholar
• Apter FM, Michetti P, Winner LS III, et al. Analysis of the roles of antilipopolysaccharide and anti-cholera toxin immunoglobulin A (IgA) antibodies in protection against Vibrio cholerae and cholera toxin by use of monoclonal IgA antibodies in vivo. Infect Immun 1993;61:5279–5285
   PubMed Web of Science ®Google Scholar
• Kerr MA. The structure and function of human IgA. Biochem J 1990;271:285–296
   PubMed Web of Science ®Google Scholar
• Duchez S, Amin R, Cogne N, et al. Premature replacement of μ with α-immunoglobulin chains impairs lymphopoiesis and mucosal homing but promotes plasma cell maturation. Proc Natl Acad Sci USA 2010;107:3064–3069
   PubMed Web of Science ®Google Scholar
• Launay P, Grossetete B, Arcos-Fajardo M, et al. Fcα receptor (CD89) mediates the development of immunoglobulin A (IgA) nephropathy (Berger's disease). Evidence for pathogenic soluble receptor-Iga complexes in patients and CD89 transgenic mice. J Exp Med 2000;191:1999–2009
   PubMed Web of Science ®Google Scholar
• Mostov KE. Transepithelial transport of immunoglobulins. Annu Rev Immunol 1994;12:63–84
   PubMed Web of Science ®Google Scholar
• Stockert RJ, Kressner MS, Collins JC, et al. IgA interaction with the asialoglycoprotein receptor. Proc Natl Acad Sci USA 1982;79:6229–6231
   PubMed Web of Science ®Google Scholar
• Sun K, Johansen FE, Eckmann L, Metzger DW. An important role for polymeric Ig receptor-mediated transport of IgA in protection against Streptococcus pneumoniae nasopharyngeal carriage. J Immunol 2004;173:4576–4581
   PubMed Web of Science ®Google Scholar
• Dotzauer A, Gebhardt U, Bieback K, et al. Hepatitis A virus-specific immunoglobulin A mediates infection of hepatocytes with hepatitis A virus via the asialoglycoprotein receptor. J Virol 2000;74:10950–10957
   PubMed Web of Science ®Google Scholar
• Hjelm F, Carlsson F, Getahun A, Heyman B. Antibody-mediated regulation of the immune response. Scand J Immunol 2006;64:177–184
   PubMed Web of Science ®Google Scholar
• Getahun A, Hjelm F, Heyman B. IgE enhances antibody and T cell responses in vivo via CD23+ B cells. J Immunol 2005;175:1473–1482
   PubMed Web of Science ®Google Scholar
• Yamaki K, Yoshino S. Tyrosine kinase inhibitor sunitinib relieves systemic and oral antigen-induced anaphylaxes in mice. Allergy 2012;67:114–122
   PubMed Web of Science ®Google Scholar
• Yamaki K, Alam AH, Hossain MA, et al. Effect of rolipram, a phosphodiesterase IV inhibitor, on allergic footpad swelling using various adjuvants in mice. Scand J Immunol 2005;62:378–384
   PubMed Web of Science ®Google Scholar
• Ozdemir C, Akdis M, Akdis CA. T regulatory cells and their counterparts: masters of immune regulation. Clin Exp Allergy 2009;39:626–639
   PubMed Web of Science ®Google Scholar
• Hess C, Winkler A, Lorenz AK, et al. T cell-independent B cell activation induces immunosuppressive sialylated IgG antibodies. J Clin Invest 2013;123:3788–3796
   Google Scholar
• Silva SR, Casabuono A, Jacysyn JF, et al. Sialic acid residues are essential for the anaphylactic activity of murine IgG1 antibodies. J Immunol 2008;181:8308–8314
   PubMed Web of Science ®Google Scholar
• Strait RT, Mahler A, Hogan S, et al. Ingested allergens must be absorbed systemically to induce systemic anaphylaxis. J Allergy Clin Immunol 2011;127:982–989.e1
   PubMed Web of Science ®Google Scholar
• Matson AP, Thrall RS, Rafti E, et al. IgG transmitted from allergic mothers decreases allergic sensitization in breastfed offspring. Clin Mol Allergy 2010;8:9
   PubMedGoogle Scholar
• Nakata K, Kobayashi K, Ishikawa Y, et al. The transfer of maternal antigen-specific IgG regulates the development of allergic airway inflammation early in life in an FcRn-dependent manner. Biochem Biophys Res Commun 2010;395:238–243
   PubMed Web of Science ®Google Scholar
• Elazab MF, Fukushima Y, Fujita Y, et al. Induction of immune suppression in the chick by an optimal dose of an immunizing antigen in the presence of its specific maternal antibody. J Vet Med Sci 2010;72:257–262
   PubMed Web of Science ®Google Scholar
• Diana J, Moura IC, Vaugier C, et al. Secretory IgA induces tolerogenic dendritic cells through SIGNR1 dampening autoimmunity in mice. J Immunol 2013;191:2335–2343
   PubMed Web of Science ®Google Scholar
• Getahun A, Heyman B. Studies on the mechanism by which antigen-specific IgG suppresses primary antibody responses: evidence for epitope masking and decreased localization of antigen in the spleen. Scand J Immunol 2009;70:277–287
   PubMed Web of Science ®Google Scholar
• Daeron M. Fc receptor biology. Annu Rev Immunol 1997;15:203–234
   PubMed Web of Science ®Google Scholar
• Yamaki K, Nakashima T, Miyatake K, et al. IgA attenuates anaphylaxis and subsequent immune responses in mice: possible application of IgA to vaccines. Immunol Res 2014;58:106–117
   PubMed Web of Science ®Google Scholar