A novel fibrinogenase from Agkistrodon acutus venom protects against LPS-induced endotoxemia via regulating NF-κB pathway

References

• Nandi D, Mishra MK, Basu A, Bishayi B. Protective effects of interleukin-6 in lipopolysaccharide (LPS)-induced experimental endotoxemia are linked to alteration in hepatic anti-oxidant enzymes and endogenous cytokines. Immunobiology 2010;215:443–451
   PubMed Web of Science ®Google Scholar
• Tang Y, Lv B, Wang H, et al. PACAP inhibit the release and cytokine activity of HMGB1 and improve the survival during lethal endotoxemia. Int Immunopharmacol 2008;8:1646–1651
   PubMed Web of Science ®Google Scholar
• Poltorak A, He X, Smirnova I, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998;282:2085–2088
   PubMed Web of Science ®Google Scholar
• Terrando N, Fidalgo AR, Vizcaychipi M, et al. The impact of IL-1 modulation on the development of lipopolysaccharide-induced cognitive dysfunction. Critical Care [Online] 2010;14:R88. Available at: http://ccforum.com/content/14/3/R88
   PubMed Web of Science ®Google Scholar
• Caironi P, Tognoni G, Masson S, et al. Albumin replacement in patients with severe sepsis or septic shock. N Engl J Med 2014;370:1412–1421
   PubMed Web of Science ®Google Scholar
• Jayashankar B, Mishra KP, Ganju L, Singh SB. Supercritical extract of Seabuckthorn Leaves (SCE200ET) inhibited endotoxemia by reducing inflammatory cytokines and nitric oxide synthase 2 expression. Int Immunopharmacol 2014;20:89–94
   PubMed Web of Science ®Google Scholar
• Noh KT, Son KH, Jung ID, et al. Protein kinase C delta (PKC delta)-extracellular signal-regulated kinase 1/2 (ERK1/2) signaling cascade regulates glycogen synthase kinase-3 (GSK-3) inhibition-mediated interleukin-10 (IL-10) expression in lipopolysaccharide (LPS)-induced endotoxemia. J Biol Chem 2012;287:14226–14233
   PubMed Web of Science ®Google Scholar
• Lehmann C, Scheibe R, Schade M, et al. Effects of activated protein C on the mesenteric microcirculation and cytokine release during experimental endotoxemia. Can J Anaesth 2008;55:155–162
   PubMed Web of Science ®Google Scholar
• Rim HK, Cho W, Sung SH, Lee KT. Nodakenin suppresses lipopolysaccharide-induced inflammatory responses in macrophage cells by inhibiting tumor necrosis factor receptor-associated factor 6 and nuclear factor-kappa b pathways and protects mice from lethal endotoxin shock. J Pharmacol Exp Ther 2012;342:654–664
   PubMed Web of Science ®Google Scholar
• Yang M, Cao L, Xie M, et al. Chloroquine inhibits HMGB1 inflammatory signaling and protects mice from lethal sepsis. Biochem Pharmacol 2013;86:410–418
   PubMed Web of Science ®Google Scholar
• Baker AK, Wang RP, Mackman N, Luyendyk JP. Rapamycin enhances LPS induction of tissue factor and tumor necrosis factor-alpha expression in macrophages by reducing IL-10 expression. Mol Immunol 2009;46:2249–2255
   PubMed Web of Science ®Google Scholar
• Abhilash PA, Harikrishnan R, Indira M. Ascorbic acid suppresses endotoxemia and NF-kappaB signaling cascade in alcoholic liver fibrosis in guinea pigs: a mechanistic approach. Toxicol Appl Pharmacol 2014;274:215–224
   PubMed Web of Science ®Google Scholar
• Kim JY, Kim HJ, Kim SM, et al. Methylene chloride fraction of the leaves of Thuja orientalis inhibits in vitro inflammatory biomarkers by blocking NF-kappa B and p38 MAPK signaling and protects mice from lethal endotoxemia. J Ethnopharmacol 2011;133:687–695
   PubMed Web of Science ®Google Scholar
• Ye XB, Ding JQ, Zhou XZ, et al. Divergent roles of endothelial NF-kappa B in multiple organ injury and bacterial clearance in mouse models of sepsis. J Exp Med 2008;205:1303–1315
   PubMed Web of Science ®Google Scholar
• Georgieva D, Arni RK, Betzel C. Proteome analysis of snake venom toxins: pharmacological insights. Expert Rev Proteomic 2008;5:787–797
   PubMed Web of Science ®Google Scholar
• Cintra AC, De Toni LG, Sartim MA, et al. Batroxase, a new metalloproteinase from B. atrox snake venom with strong fibrinolytic activity. Toxicon 2012;60:70–82
   PubMed Web of Science ®Google Scholar
• Liang XX, Chen JS, Zhou YN, et al. Purification and biochemical characterization of FIIa, a fibrinolytic enzyme from Agkistrodon acutus venom. Toxicon 2001;39:1133–1139
   PubMed Web of Science ®Google Scholar
• Liang XX, Zhou YN, Chen JS, et al. Enzymological characterization of FIIa, a fibrinolytic enzyme from Agkistrodon acutus venom. Acta Pharmacol Sin 2005;26:1474–1478
   PubMed Web of Science ®Google Scholar
• Chen JS, Liang XX, Qiu PX, Yan GM. Thrombolysis effect with FII (a) from Agkistrodon acutus venom in different thrombosis model. Acta Pharmacol Sin 2001;22:420–422
   PubMed Web of Science ®Google Scholar
• Qi JZ, Lin X, Chen JS, et al. A novel fibrinogenase from Agkistrodon acutus venom protects against DIC via direct degradation of thrombosis and activation of protein C. Biochem Pharmacol 2012;84:905–913
   PubMed Web of Science ®Google Scholar
• Guan S, Feng HH, Song BC, et al. Salidroside attenuates LPS-induced pro-inflammatory cytokine responses and improves survival in murine endotoxemia. Int Immunopharmacol 2011;11:2194–2199
   PubMed Web of Science ®Google Scholar
• Szeto CC, Kwan BCH, Chow KM, et al. Endotoxemia is associated with better clinical outcome in incident Chinese peritoneal dialysis patients: a prospective cohort study. Perit Dial Int 2010;30:178–186
   PubMed Web of Science ®Google Scholar
• Yan YJ, Li Y, Lou B, Wu MP. Beneficial effects of ApoA-I on LPS-induced acute lung injury and endotoxemia in mice. Life Sci 2006;79:210–215
   PubMed Web of Science ®Google Scholar
• Guo Y, Zhang Y, Hong K, et al. AMPK inhibition blocks ROS-NF kappa B signaling and attenuates endotoxemia-induced liver injury. PLoS One [Online] 2014;9:e86881. Available at: http://www.plosone.org/article/fetchObject.actionuri=info:doi/10.1371/journal.pone.0086881&representation=PDF
   PubMed Web of Science ®Google Scholar
• Aslami H, Beurskens CJP, de Beer FM, et al. A short course of infusion of a hydrogen sulfide-donor attenuates endotoxemia induced organ injury via stimulation of anti-inflammatory pathways, with no additional protection from prolonged infusion. Cytokine 2013;61:614–621
   PubMed Web of Science ®Google Scholar
• Gonzalo S, Grasa L, Arruebo MP, et al. Inhibition of p38 MAPK improves intestinal disturbances and oxidative stress induced in a rabbit endotoxemia model. Neurogastroenterol Motil 2010;22:564–572
   PubMed Web of Science ®Google Scholar
• Cao W, Li XQ, Zhang XN, et al. Madecassoside suppresses LPS-induced TNF-alpha. production in cardiomyocytes through inhibition of ERK, p38, and NF-kappa B activity. Int Immunopharmacol 2010;10:723–729
   PubMed Web of Science ®Google Scholar
• Soromou LW, Chen N, Jiang LN, et al. Astragalin attenuates lipopolysaccharide-induced inflammatory responses by down-regulating NF-kappa B signaling pathway. Biochem Biophys Res Commun 2012;419:256–261
   PubMed Web of Science ®Google Scholar