24
Views
15
CrossRef citations to date
0
Altmetric
Research Article

Augmentation of Antimetastatic Activity of Interferon and Tumor Necrosis Factor by Heparin

, &
Pages 161-180 | Published online: 28 Sep 2008

References

  • Helson L., Green S., Carswell E., Old L. J. Effect of tumor necrosis factor on cultured melanoma cells. Nature 1975; 258: 731
  • Haranaka K., Satomi N., Sakurai A. Antitumor activity of murine tumor necrosis factor (TNF) against transplanted murine tumors and heterotransplanted human tumors in nude mice. Int. J. Cancer 1984; 34: 263
  • Sugarman B. J., Aggarwal B. B., Hass P. E., Figari I. S., Palladino M. A., Shepard H. M. Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro. Science 1985; 230: 943
  • Williamson B. D., Carswell E. A., Rubin B. Y., Prendergast J. S., Old L. J. Human tumor necrosis factor produced by human B-cell lines: synergistic cytotoxic interaction with human interferon. Proc. Natl. Acad. Sci. USA 1983; 80: 5397
  • Ruff M. R., Gifford G. E. Tumor necrosis factor, in Lymphokines. Academic Press, New York 1981; Vol 2
  • Tsujimoto M., Yip Y. K., Vilcek J. Tumor necrosis factor: specific binding and internalization in sensitive and resistant cells. Cell Biol. 1985; 82: 7626
  • Ostensen M. E., Thiele D. L., Lipsky P. E. Tumor necrosis factor enhances cytolytic activity of human natural killer cells. J. Immunol. 1987; 138: 4185
  • Vilcek J., Gray P. W., Rinderknecht E., Sevastopoulos C. G. Interferon-gamma: a lymphokine for all seasons. Lymphokines, E. p.I Pick. Academic Press, Orlando 1984
  • Ortaldo J. R. Regulation of natural killer activity. Cancer and Metast. Rev. 1987; 6: 637
  • Taguchi T., Kimoto Y., Tanji Y., Abe S., Nakano K., Sohmura Y. Augmentation of cytotoxic activity of recombinant human tumor necrosis factor (rHu-TNF) by recombinant human interferon-gamma (rHu-IFN-gamma). J. Biol. Res. Mod. 1987; 6: 599
  • Brouckaert P. G.G., Leroux-Roels G. G., Guisez Y., Tavernier J., Fiers W. In vivo anti-tumor activity of recombinant human and murine TNF. alone and in combination with murine IFN, on a syngeneic murine melanoma, Int. J. cancer 1986; 38: 763
  • McMillan T. J., Rao J., Everett C. A., Hart I. R. Interferon-induced alterations in metastatic capacity. class-1 antigen expression and natural killer cell sensitivity of melanoma cells, Int. J. Cancer 1987; 40: 659
  • Aggarwal B., Eesaulu T. E., Hass P. E. Characterization of receptors for human tumor necrosis factor and their regulation by gamma-interferon. Nature (Lond.) 1985; 318: 665
  • Tsujimoto M., Yip Y. K., Vilceck J. Interferon-gamma enhances expression of cellular receptors for tumor necrosis factor. J. Immunol. 1986; 136: 2441
  • Ruggiero V., Tavernier J., Fiers W., Baglioni C. Induction of the synthesis of tumor necrosis factor receptors by interferon-gamma. J. Immunol. 1986; 136: 2445
  • Dinarello C. A., Cannon J. G., Wolff S. M., Bernheirm H. A., Beutler B., Cerami A., Figari I. S., Palladino M. A., Jr., O'Connor J. V. Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1. J. Exp. Med. 1986; 163: 1433
  • Chapekar M. S., Glazer R. I. The synergistic cytocidal effect produced by immune interferon and tumor necrosis factor in HT-29 cells is associated with inhibition of rRNA processing and (2′,5′)oligo(A) activation of RNase L. Biochem. Biophys. Res. commun. 1988; 151: 1180
  • Talmadge J. E., Bowersox O., Tribble H., Lee S. H., Shepard M., Leggitt D. Toxicity of tumor necrosis factor is synergistic with IFN-gamma and can be reduced with cyclooxygenase inhibitors. Am. J. Pathol. 1987; 128: 410
  • Bevilacqua M. P., Pober J. S., Majeau G. R., Fiers W., Cotran R. S., Gimbrone M. S. Recombinant tumor necrosis factor induces procoagulant activity in cultured human vascular endothelium: characterization and comparison with the actions of interleukin 1. Proc. Natl. Acad. Sci., (USA) 1986; 83: 4533
  • Nawroth P. P., Stern D. M. Modulation of endothelial cell hemostatic properties by tumor necrosis factor. J. Exp. Med. 1986; 163: 740
  • Regelson W. The antimitotic activity of polyanions (antitumor. antiviral, and antibacterial action of heparin, heparinoids, anionic dyes, and synthetic polymers), Adv. Chemotherapy 1968; 3: 303
  • Jaques L. B. The new understanding of the drug heparin. Chest 1985; 5: 751
  • Eskinazi D. P., Perna J. J., Ershow A. G., Sharrow S. O. Effects of heparin on in vitro immune parameters. J. Biol. Resp. Mod. 1988; 7: 173
  • Gorelik E., Bere W. W., Herberman R. B. Role of NK cells in the antimetastatic effect of anticoagulant drugs. Int. J. Cancer 1984; 33: 87
  • Irimura T., Nakajima M., Nicolson G. L. Chemically modified heparins as inhibitors of heparan sulfate specific endo-beta-glucuronidase (heparanase) of metastatic melanoma cells. Biochemistry 1986; 25: 5322
  • Gorelik E. Augmentation of the antimetastatic effect of anticoagulant drugs by immunostimulation in mice. Cancer Res. 1987; 47: 809
  • Abdallah R. M., Starkey J. R., Meadows G. G. Alcohol and related dietary effects on mouse natural killer-cell activity. Immunology 1983; 50: 131
  • Pross H. F., Baines M. G., Rubin P., Shragge P., Patterson M. S. Spontaneous human lymphocyte-mediated cytotoxicity against tumor target cells. IX: the quantitation of natural killer cell activity. J. Clin. Immunol. 1981; 1: 51
  • Clauss A. Gerinnungs physiologische schenell methods zur bestimmung des fibrinogens. Acta Haematol. 1957; 17: 237
  • Ranby M., Norrman B., Wallen P. A sensitive assay for tissue plasminogen activator. Thromb. Res. 1982; 27: 743
  • Talmadge J. E., Tribble H. R., Pennington R. W., Phillips H., Wiltrout R. H. Immunomodulatory and Immunotherapeutic properties of recombinant gamma-interferon and recombinant tumor necrosis factor in mice. Cancer Res. 1987; 47: 2563
  • Edwards B. S., Merritt J. A., Fuhlbrigge R. C., Borden E. C. Low doses of interferon alpha result in more effective clinical natural killer cell activation. J. Clin. Invest. 1908; 75, 1985
  • Talmadge J. E., Herberman R. B., Chirgos M. A., Maluish A. E., Schneider M. A., Adams J. S., Phillips H., Thurman G. B., Varesio L., Long C. W., Oldham R. K., Wiltrout R. H. Hyporesponsiveness to augmentation of murine natural killer cell activity in different anatomical compartments by multiple injections of various immunomodulators including recombinant interferons and interleukin 2. J. Immunol. 1985; 135: 2483
  • Ortaldo J. R. Regulation of natural killer activity. Cancer and Metas. Rev. 1987; 6: 637
  • Bravo Cuellar A., Martin Ruiz J. L., Orbach-Arbouys S. Decreased natural killer cell activity after prolonged administration of interferon in cancer patients. Immunol. Letters 1985; 10: 137
  • Pineo G. F., Regoeczi E., Hatton M. W.C., Brain M. C. The activation of coagulation by extracts of mucus: a possible pathway of intravascular coagulation accompanying adenocarcinoma. J. Lab. Clin. Med. 1973; 82: 255
  • Gordon S. G., Franks J. J., Lewis B. Cancer procoagulant A: a factor X activating procoagulant from malignant tissue. Thromb. Res. 1975; 6: 127
  • Colucci M., Curatolo L., Donati M. B., Semeraro N. Cancer cell procoagulant activity: evaluation by an amydolytic assay. Thromb. Res. 1980; 18: 589
  • Rickles F. R., Hancock W. W., Edwards R. L., Zacharski L. R. Antimetastatic agents. I. Role of cellular procoagulants in the pathogenesis of fibrin deposition in cancer and the use of anticoagulants and/or antiplatelet drugs in cancer treatment. Sem. Thromb. Hemost. 1988; 14: 88
  • Miller S. P., Sanchez-Avalos J., Stefanski T., Zucherman L. Coagulation disorders in cancer. I. Clinical and laboratory studies. Cancer 1967; 20: 1452
  • Brugarolas A., Mink I. B., Elias E. G., Mittelman A. Correlation of hyperfibrinogenemia with major thromboembolism in patients with cancer. SGO 1973; 136: 75
  • Agostino D., Cliffton E. E. Fibrinogen levels and pulmonary metastasis in rats. Arch. Pathol. 1969; 87: 141
  • Laki K. Fibrinogen and metastasis. J. Med. 1974; 5: 32
  • Peterson H. I., Larsson S., Zettergren L. Fibrinolysis in human bronchogenic carcinoma. Eur. J. Cancer 1975; 11: 277
  • Malone J. M., Wangensteen S. L., Moore W. S., Keown K. The fibrinolytic system a key to tumor metastasis?. Ann. Surg. 1979; 190: 342
  • Colombi M., Rebessi L., Boiocchi M., Barlati S. Relationship between circulating plasminogen activators and tumor development in mice. Cancer Res. 1986; 46: 5748
  • Dano K., Andreasen P. A., Grondahl-Hansen J., Kristensen P., Nilsen L. S., Skriver L. Plasminogen activators. tissue degradation, and cancer, Adv. Cancer Res. 1985; 44: 140
  • Fareed J., Walenga J. M., Hoppensteadt D. A., Messmore H. L. Studies on the profibrinolytic actions of heparin and its fractions. Sem. Thromb. Hem. 1985; 11: 199
  • Beutler B., Mahoney J., LeTrang N., Pekala P., Cerami A. Purification of cachectin. a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cells, J. Exp. Med. 1985; 161: 984
  • Kurzrock R., Rohde M. R., Quesada J. R., Gianturco S. H., Bradley W. A., Sherwin S. A., Gutterman J. U. Recombinant gamma-interferon induces hypertriglyceridemia and inhibits post-heparin lipase activity in cancer patients. J. Exp. Med. 1986; 164: 1093
  • Watanabe N., Niitsu Y., Yamauchi N., Umeno H., Sone H., Neda H., Urushizaki I. Antitumor synergism between recombinant human tumor necrosis factor and recombinant human interferon-r. J. Biol. Resp. Mod. 1988; 7: 24
  • Bollon A. P., Berent S. L., Torczynski R. M., Hill N. O., Lemeshev Y., Hill J. M., Jia F. L., Joher A., Pichyangkul S., Khan A. Human cytokines. tumor necrosis factor, and interferons: gene cloning, animal studies, and clinical trials, J. Cell Biochem 1988; 36: 353
  • Rickles F. R., Hancock W. W. Antimetastatic agents. II. Summary of the interactions of tumor cells with blood coagulation factors. platelets, fibrinolytic factors, and inflammatory cells and their soluble mediators: Potential for therapeutic interventions, Semin. Thromb. Hemostat. 1988; 14: 126
  • Yamamoto H., Fuyama S., Arai S., Sendo F. Inhibition of mouse natural killer cytotoxicity by heparin. Cell. Immunol. 1985; 96: 409
  • Zoller M., Strubel A., Hammerling G., Andrighetto G., Raz A., Ben-Ze'ev A. Interferon-gamma treatment of B16 melanoma cells: Opposing effects for non-adaptive and adaptive immune defense and its reflection by metastatic spread. Int. J. Cancer 1988; 41: 256
  • Hanna N. Role of natural killer cells in control of cancer metastasis. Cancer Metastasis Rev. 1982; 1: 45
  • Barlozzari T., Leonhardt J., Wiltrout R. H., Herberman R. B., Reynolds C. W. Direct evidence for the role of NK cells in the inhibition of tumor metastasis. J. Immunol. 1985; 134: 2783
  • Wiltrout R. H., Herberman R. B., Zhang S-R., Chirigos M. A., Ortaldo J. R., Green K. M., Talmadge J. E. Role of organ-associated NK cells in decreased formation of experimental metastases in lung and liver. J. Immunol. 1985; 134: 4267

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.