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Research Article

The Antifolate 10-Deazaaminopterin Inhibits Neutrophil Chemotaxis and Superoxide Generation

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Pages 379-393 | Published online: 28 Sep 2008

References

  • Abramson S. B., Weissmann G. The mechanisms of action of nonsteroidal anti inflammatory drugs, Arthritis & Rheumatism 1989; 32: 1–9
  • Baugh C. M., Krumdiek C. L., Nair M. G. Polygammaglutamyl metabolites of methotrexate, Biochem Biophys Res Commun 1973; 52: 27–34
  • Bellavite P. The superoxide-forming enzymatic system of phagocytes, Free Rad Biol Med 1988; 4: 225–261
  • Cohen H. J., Chovaniec M. E. Superoxide generation by digitonin-stimulated guinea pig granulocytes. J Clin Invest 1978; 61: 1081–1087
  • Cream J. J., Pole D. S. The effect of methotrexate and hydroxyurea on neutrophil chemotaxis, Brit. J Dermatol 1980; 102: 557–563
  • DeGraw J. I., Brown V. H., Tagawa H., Kisliuk R. L., Gaumont Y., Sirotniak F. M. Synthesis and antitumor activity of 10-alkyl-10-deazaminopterins. A convenient synthesis of 10-deazaminopterin. J Med Chem 1982; 25: 1227
  • Dezube B. J., Eder J. P., Pardee A. Phase I trial of escalating pentoxifylline dose with constant dose of thiotepa. Cancer Res 1990; 50: 6806–6810
  • Freyburger G., Hammerschmidt D. E., Coppo P. A., Boisseau M. R. Leukocyte activation and rheological changes: effect of pentoxifylline. Pentoxifylline and leukocyte function, G. L. Mandell, W. J. Novick, Somerville, N.J. 1988; 82–95
  • Gilliland B. C., Mannik M. Rheumatoid arthritis. Harrison's principles of internal medicine, K. J. Isselbacher, D. A. Raymond, E. Braunwald, R. G. Petersdorf, J. D. Wilson, et al. McGraw-Hill, New York 1980; 1872–1880
  • Goldman I. D. (1985) Proceedings of the second workshop on folyl and antifolyl polyglutamates. 1985. Praeger Scientific, New York
  • Hall C. W., Liebaers I., Di Natale P., Neufeld E. F. Enzymic diagnosis of the genetic mucopolysaccharide storage disorders. Methods in Enzymology. Volume L. Complex Carbohydrates. Part C, V. Ginsburg. Academic Press, New York, San Francisco, London 1978; 4390–456
  • Hohn D. C., Lehrer R. I. NADPH oxidase deficiency in X-linked chronic granulomatous disease. J Clin Invest 1975; 55: 707–713
  • Hyams J. S., Donaldson M. H., Metcalf J. A., Root R. K. Inhibition of human granulocyte function by methotrexate. Cancer Res 1978; 38: 650–655
  • Jandl R. C., Andre'-Schwartz J., Borges-DuBois L., Kipnes R. S., McMurrich B. J., Babior B M. Termination of the respiratory burst in human neutrophils. J Clin Invest 1989
  • Jones H. P., Ghai G., Petrone W. F., McCord J. M. Calmodulin-dependent stimulation of the NADPH oxidase of human neutrophils. Biochim Biophys Acta 1982; 714: 152–156
  • McCord J. M., Salin M. L. Self-directed cytotoxicity of phagocyte-generated superoxide free radical. Movement, Metabolism and Bactericidal Mechanisms of Phagocytes, F. Rossi, P. Patriarca, D. Romeo. Piccin Medical Books, Padova 1977; 257–264
  • MacFadden D. K., Saito S., Pruzanski W. The effect of chemotherapeutic agents on chemotaxis and random migration of human leukocytes. J Clin Oncology 1985; 3: 415–419
  • Melby K., Quie P. G. Effects of methotrexate, ampicillin and gentamicin alone and in combination on the in vitro locomotion on human polymorphonuclear cells (PMNs). Acta Path Microbiol Immunol Scand 92, Section 1984; C: 331–333
  • Michell R. H., Karnovsky M. J., Karnovsky M. L. The distribution of some granule-associated enzymes in guinea-pig polymorphonuclear leukocytes. Biochem J 1970; 116: 207–216
  • Nair M. G. Synthesis of 10-deazaaminopterin (10-DAAM) and 10-ethyl-10-deazaaminopterin (10-EDAAM). J Org Chem 1985; 50: 1879
  • Nair M. G., Nanavati N. T., Kumar P., Gaumont Y., Kisliuk R. L. Synthesis and biological evaluation of poly-gamma-glutamyl metabolites of 10-deazaaminopterin and 10-ethyl-deazaaminopterin. J Med Chem 1988; 31: 181–185
  • O'Callaghan J. W., Forrest M. J., Brooks P M. Inhibition of neutrophil chemotaxis in methotrexate-treated rheumatoid arthritis patients. Rheumatol Int 1988; 8: 41–45
  • Thompson E., Sarab-Al-Nakeeb. Effect of leukaemia therapy on neutrophil chemotaxis. J Clin Path 1981; 34: 371–376

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