Advanced search
Publication Cover
Immunopharmacology and Immunotoxicology Volume 14, 1992 - Issue 1-2
Submit an article Journal homepage
22
Views
14
CrossRef citations to date
0
Altmetric
Research Article

Antiallergic Effect of Epinastine (WAL 801 CL) on Immediate Hypersensitivity Reactions: (II) Antagonistic Effect of Epinastine on Chemical Mediators, Mainly Antihistamine and Anti-PAF Effects

Chiaki Kamei Department of Pharmacology, Faculty of Pharmaceutical Sciences, Okayama University, Okayama, 700, Japan
,
Mitsunobu Mio Department of Pharmacology, Faculty of Pharmaceutical Sciences, Okayama University, Okayama, 700, Japan
,
Kazuhiro Kitazumi Department of Pharmacology, Faculty of Pharmaceutical Sciences, Okayama University, Okayama, 700, Japan
,
Susumu Tsujimoto Department of Pharmacology, Faculty of Pharmaceutical Sciences, Okayama University, Okayama, 700, Japan
,
Tomokazu Yoshida Department of Pharmacology, Faculty of Pharmaceutical Sciences, Okayama University, Okayama, 700, Japan
,
Yukihiro Adachi Department of Pharmacology, Faculty of Pharmaceutical Sciences, Okayama University, Okayama, 700, Japan
&
Kenji Tasaka Department of Pharmacology, Faculty of Pharmaceutical Sciences, Okayama University, Okayama, 700, Japan
 show all
Pages 207-218 | Published online: 28 Sep 2008

References

  • Tasaka K., Akagi M., Izushi K., Aoki I. Antiallergic effect of epinastine: the elucidation of the mechanism. Oyo Yakuri/Pharmacometries 1990; 39: 365
  • Awouters F. H. L., Niemegeers C. J. E., Janssen P. A.J. Pharmacology of the specific histamine H1-antagonist astemizole. Arzneim-Forsch. 1983; 33: 381
  • Ohmori K., Ishii H., Nito M., Shuto K., Nakamizo N. Pharmacological studies on oxatomide (KW-4354). (7) Antagonistic effects on chemical mediators. Folia Pharmacol. Japon. 1983; 81: 399
  • Criscuoli M., Subissi A., Daffonchio L., Omini C. LG 30435, a new bronchodilator/antiallergic agent, inhibits PAF-acether induced platelet aggregation and bronchoconstriction. Agents Actions 1986; 19: 246
  • Kojima M, Tsutsumi N., Abe M., Komatsu H., Ujiie A., Naito J., Nakazawa M. Experimental allergic rhinitis in rats and the influence of tranilast and antihistaminics on it. Jpn. J. Allergol. 1986; 35: 180
  • Akagi M., Tasaka K. Analysis of bronchomotor tone in anesthetized guinea pigs by impedance plethysmography: a simple method for the evaluation of bronchodilator action. Meth. Find. Exp. Clin. Pharmacol. 1988; 10: 143
  • Bechtel W. D., Mierau J. In vitro biochemical comparison of WAL 801, astemizole, and terfenadine. Boehringer Ingelheim KG Report 1986; 1, U86-0298
  • Casals-Stenzel J., Muacevic G., Weber K-H. WEB 2086, a new specific antagonist of platelet activating factor (PAF) in vitro and in vivo. Arch. Pharmac 1986; 334: R44
  • Casals-Stenzel J., Muacevic G., Weber K-H. Pharmacological actions of WEB 2086, a new specific antagonist of platelet activating factor. J. Pharmacol, exp. Ther. 1987; 241: 974
  • Lewis A. J., Dervinis A., Chang J. The effects of antiallergic and bronchodilator drugs on platelet-activating factor (PAF-acether) induced bronchospasm and platelet aggregation. Agents Actions 1984; 15: 636
  • Piper P. J. Formation and actions of leukotrienes. Physiol. Rev. 1984; 64: 744

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.