Advanced search
Publication Cover
Journal of Investigative Surgery Volume 22, 2009 - Issue 6
Submit an article Journal homepage
64
Views
3
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Effects of CO2 Pneumoperitoneum on Anastomotic Healing in Rats Receiving Preoperative 5-Fluorouracil Neoadjuvant Chemotherapy

Murat UlasDepartment of Gastroenterological Surgery, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, TurkeyCorrespondence[email protected]
,
Ilter OzerDepartment of Gastroenterological Surgery, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey
,
Metin ErcanDepartment of Gastroenterological Surgery, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey
,
Yusuf B. OzogulDepartment of Gastroenterological Surgery, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey
,
E. Birol BostanciDepartment of Gastroenterological Surgery, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey
,
Tulay Temucin KeklikDepartment of Pathology, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey
,
Ummuhani Ozel TurkcuDepartment of Biochemistry, Mugla University School of Health, Mugla, Turkey
,
Ayse BilgihanDepartment of Biochemistry, Gazi University School of Medicine, Ankara, Turkey
&
Musa AkogluDepartment of Gastroenterological Surgery, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey
 show all
Pages 413-418 | Received 12 Mar 2009, Accepted 28 Apr 2009, Published online: 15 Dec 2009

REFERENCES

  • Moser L, Ritz JP, Hinkelbein W, Adjuvant and neoadjuvant chemoradiation or radiotherapy in rectal cancer—a review focusing on open questions. Int J Colorectal Dis. 2008;23:227–236.
  • Sugarbaker PH, Gianola FJ, Speyer JC, Prospective, randomized trial of intravenous versus intraperitoneal 5-fluorouracil in patients with advanced primary colon or rectal cancer. Surgery. 1985;98:414–422.
  • Kuzu MA, Kuzu I, Köksoy C, Histological evaluation of colonic anastomotic healing in the rat following preoperative 5-fluorouracil, fractionated irradiation, and combined treatment. Int J Colorectal Dis. 1998;13:235–240.
  • Weiber S, Graf W, Glimelius B, The effect of 5-fluorouracil on wound healing and collagen synthesis in left colon anastomoses. An experimental study in the rat. Eur Surg Res. 1994;26:173–178.
  • Kuzu MA, Köksoy C, Kale T, Experimental study of the effect of preoperative 5-fluorouracil on the integrity of colonic anastomoses. Br J Surg. 1998;85:236–239.
  • Fazio VW, López-Kostner F. Role of laparoscopic surgery for treatment of early colorectal carcinoma. World J Surg. 2000;24:1056–1060.
  • Ishizaki Y, Bandai Y, Shimomura K, Changes in splanchnic blood flow and cardiovascular effects following peritoneal insufflation of carbon dioxide. Surg Endosc. 1993;7:420–423.
  • Ishizaki Y, Bandai Y, Shimomura K, Safe intraabdominal pressure of carbon dioxide pneumoperitoneum during laparoscopic surgery. Surgery. 1993;114:549–554.
  • Jakimowicz J, Stultiëns G, Smulders F. Laparoscopic insufflation of the abdomen reduces portal venous flow. Surg Endosc. 1998;12:129–132.
  • Kologlu M, Sayek I, Kologlu LB, Effect of persistently elevated intraabdominal pressure on healing of colonic anastomoses. Am J Surg. 1999;178:293–297.
  • Polat C, Arikan Y, Vatansev C, The effects of increased intraabdominal pressure on colonic anastomoses. Surg Endosc. 2002;16:1314–1319.
  • Jamall IS, Finelli VN, Que Hee SS. A simple method to determine nanogram levels of 4-hydroxyproline in biological tissues. Anal Biochem. 1981;112:70–75.
  • Verhofstad MH, Lange WP, van der Laak JA, Microscopic analysis of anastomotic healing in the intestine of normal and diabetic rats. Dis Colon Rectum. 2001;44:423–431.
  • de Waard JW, Wobbes T, de Man BM, The effects of 5-fluorouracil and interferon-alpha on early healing of experimental intestinal anastomoses. Br J Cancer. 1996;74:711–716.
  • Kanellos I, Odisseos C, Zaraboukas T, Colonic healing after early intraperitoneal administration of 5-fluorouracil and interferon in rats. Int J Colorectal Dis. 1997;12:45–48.
  • Tümer AR, Kama NA, Tümer L, Effects of 5-fluorouracil and zinc on healing of colonic anastomoses in rabbits. Eur J Surg. 1999;165:369–377.
  • van der Kolk BM, de Man BM, Wobbes T, Is early post-operative treatment with 5-fluorouracil possible without affecting anastomotic strength in the intestine? Br J Cancer. 1999;79:545–550.
  • El-Malt M, Ceelen W, De Meerleer G, Influence of preoperative combined radiochemotherapy on surgical outcome and colonic anastomotic healing: experimental study in the rat. Int J Radiat Oncol Biol Phys. 2001;50:1073–1078.
  • el-Malt M, Ceelen W, Van den Broecke C, Influence of neo-adjuvant chemotherapy with 5-fluorouracil on colonic anastomotic healing: experimental study in rats. Acta Chir Belg. 2003;103:309–314.
  • Schmandra TC, Kim ZG, Gutt CN. Effect of insufflation gas and intraabdominal pressure on portal venous flow during pneumoperitoneum in the rat. Surg Endosc. 2001;15:405–408.
  • Rosch R, Stumpf M, Junge K, Impact of pressure and gas type on anastomotic wound healing in rats. Langenbecks Arch Surg. 2004;389:261–266.
  • Rosch R, Stumpf M, Junge K, Influence of pneumoperitoneum on small bowel anastomoses: a histological analysis in the rat model. J Invest Surg. 2005;18:63–69.
  • Ozer I, Ulas M, Ercan M, The effects of duration of CO2 pneumoperitoneum on colonic anastomosis. J Invest Surg. 2008;2:177–181.
  • Brasken P. Healing of experimental colon anastomoses. Eur J Surg Suppl. 1991;566:1–51.
  • Koruda MJ, Rolandelli RH. Experimental studies on the healing of colonic anastomoses. J Surg Res. 1990;48:504–515.
  • de Roy van Zuidewijn DB, Schillings PH, Wobbes T, Histologic evaluation of wound healing in experimental intestinal anastomoses: effects of antineoplastic agents. Int J Exp Pathol. 1992;73:465–484.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.