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ORIGINAL RESEARCH

The Effect of Rabeprazole on LES Tone in Experimental Rat Model

, MD, , MD, , PhD, , PhD, , MD, , MD, , MD, , MD, , PhD & , MD show all
Pages 186-190 | Received 20 Jun 2012, Accepted 20 Sep 2012, Published online: 20 Mar 2013

REFERENCES

  • Brasseur JG, Ulerich R, Dai Q, Pharmacological dissection of the human gastro-oesophageal segment into three sphincteric components. J Physiol. 2007;580:961–975.
  • Farre R, Sifrim D. Regulation of basal tone, relaxation and contraction of the lower oesophageal sphincter. Relevance to drug discovery for oesophageal disorders. Br J Pharmacol. 2008;153:858–869.
  • Liakakos T, Karamanolis G, Patapis P, Gastroesophageal reflux disease: medical or surgical treatment? Gastroenterol Res Pract. 2009;2009:371580.
  • Pandolfino JE, Shi G, Curry J, Esophagogastric junction distensibility: a factor contributing to sphincter incompetence. Am J Physiol Gastrointest Liver Physiol. 2002;282:G1052–1058.
  • Shafik A, El-Sibai O, Shafik I. Physioanatomic study of the diaphragmatic crura: the identification of autonomous “gastroesophageal sphincter”. J Invest Surg. 2005;18:135–142.
  • Kahrilas PJ. Clinical practice. Gastroesophageal reflux disease. N Engl J Med. 2008;359:1700–1707.
  • Orlando RC. Pathophysiology of gastroesophageal reflux disease. J Clin Gastroenterol. 2008;42:584–588.
  • De Giorgi F, Palmiero M, Esposito I, Pathophysiology of gastro-oesophageal reflux disease. Acta Otorhinolaryngol Ital. 2006;26:241–246.
  • Crowell MD, Zayat EN, Lacy BE, The effects of an inhaled beta(2)-adrenergic agonist on lower esophageal function: a dose-response study. Chest 2001;120:1184–1189.
  • Moayyedi P, Talley NJ. Gastro-oesophageal reflux disease. Lancet. 2006;367:2086–2100.
  • Pace F, Pallotta S, Manes G, Outcome of nonerosive gastro-esophageal reflux disease patients with pathological acid exposure. World J Gastroenterol. 2009;15:5700–5705.
  • Zacny J, Zamakhshary M, Sketris I, Systematic review: the efficacy of intermittent and on-demand therapy with histamine H2-receptor antagonists or proton pump inhibitors for gastro-oesophageal reflux disease patients. Aliment Pharmacol Ther. 2005;21:1299–1312.
  • Patrick L. Gastroesophageal reflux disease (GERD): a review of conventional and alternative treatments. Altern Med Rev. 2011;16:116–133.
  • Berardi RR. A critical evaluation of proton pump inhibitors in the treatment of gastroesophageal reflux disease. Am J Manag Care. 2000;6:S491–505.
  • Moraes-Filho JP, Navarro-Rodriguez T, Barbuti R, Guidelines for the diagnosis and management of gastroesophageal reflux disease: an evidence-based consensus. Arq Gastroenterol. 2010;47:99–115.
  • Wetscher GJ, Glaser K, Hinder RA, Respiratory symptoms in patients with gastroesophageal reflux disease following medical therapy and following antireflux surgery. Am J Surg. 1997;174:639–642; discussion 642–633.
  • Oberg S, Johansson J, Wenner J, Endoscopic surveillance of columnar-lined esophagus: frequency of intestinal metaplasia detection and impact of antireflux surgery. Ann Surg. 2001;234:619–626.
  • Kahrilas PJ. GERD pathogenesis, pathophysiology, and clinical manifestations. Cleve Clin J Med. 2003;70 Suppl 5:S4–19.
  • Tamhankar AP, Peters JH, Portale G, Omeprazole does not reduce gastroesophageal reflux: new insights using multichannel intraluminal impedance technology. J Gastrointest Surg. 2004;8:890–897; discussion 897–898.
  • Vela MF, Camacho-Lobato L, Srinivasan R, Simultaneous intraesophageal impedance and pH measurement of acid and nonacid gastroesophageal reflux: effect of omeprazole. Gastroenterology 2001;120:1599–1606.
  • Aydin C, Sarac B, Koyuncu A, Relaxant effect of omeprazole and lansoprazole in guinea pig gallbladder muscle strips in vitro. J Gastroenterol. 2003;38:765–771.
  • Rhoden KJ, Tallini G, Douglas JS. H+-K+ ATPase inhibitors cause relaxation of guinea pig and human airway smooth muscle in vitro. J Pharmacol Exp Ther. 1996;276:897–903.
  • Sims SM, Chrones T, Preiksaitis HG. Calcium sensitization in human esophageal muscle: role for RhoA kinase in maintenance of lower esophageal sphincter tone. J Pharmacol Exp Ther. 2008;327:178–186.
  • Beaumont H, Jensen J, Carlsson A, Effect of delta9-tetrahydrocannabinol, a cannabinoid receptor agonist, on the triggering of transient lower oesophageal sphincter relaxations in dogs and humans. Br J Pharmacol. 2009;156:153–162.
  • Manabe T, Kawamitsu H, Higashino T, Observation of gastro-esophageal reflux by MRI: a feasibility study. Abdom Imaging. 2009;34:419–423.
  • Sidhu AS, Triadafilopoulos G. Neuro-regulation of lower esophageal sphincter function as treatment for gastroesophageal reflux disease. World J Gastroenterol. 2008;14:985–990.
  • Vakil N, van Zanten SV, Kahrilas P, The montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus. Am J Gastroenterol. 2006;101:1900–1920; quiz 1943.
  • Fein M, Ritter MP, DeMeester TR, Role of the lower esophageal sphincter and hiatal hernia in the pathogenesis of gastroesophageal reflux disease. J Gastrointest Surg. 1999;3:405–410.
  • Lehmann A. Novel treatments of GERD: focus on the lower esophageal sphincter. Eur Rev Med Pharmacol Sci. 2008;12 Suppl 1:103–110.
  • Boeckxstaens GE. Review article: the pathophysiology of gastro-oesophageal reflux disease. Aliment Pharmacol Ther. 2007;26:149–160.
  • Piche T, Galmiche JP. Pharmacological targets in gastro-oesophageal reflux disease. Basic Clin Pharmacol Toxicol. 2005;97:333–341.
  • Wetscher GJ, Gadenstaetter M, Klingler PJ, Efficacy of medical therapy and antireflux surgery to prevent Barrett's metaplasia in patients with gastroesophageal reflux disease. Ann Surg. 2001;234:627–632.
  • Peng S, Xiong LS, Xiao YL, Relationship between symptom response and esophageal pH level on standard dose of esomeprazole treatment for gastroesophageal reflux disease. Chin Med J (Engl). 2010;123: 2012–2017.
  • Armstrong D, Marshall JK, Chiba N, Canadian association of gastroenterology GCG. Canadian consensus conference on the management of gastroesophageal reflux disease in adults –update 2004. Can J Gastroenterol. 2005;19:15–35.
  • Hershcovici T, Fass R. Management of gastroesophageal reflux disease that does not respond well to proton pump inhibitors. Curr Opin Gastroenterol. 2010;26:367–378.
  • Wynn GH, Sandson NB, Cozza KL. Gastrointestinal medications. Psychosomatics. 2007;48:79–85.
  • Fass R, Shapiro M, Dekel R, et al. Systematic review: proton-pump inhibitor failure in gastro-oesophageal reflux disease–where next? Aliment Pharmacol Ther. 2005;22: 79–94.
  • Maiti R, Jaida J, Israel PL, Rabeprazole and esomeprazole in mild-to-moderate erosive gastroesophageal reflux disease: A comparative study of efficacy and safety. J Pharmacol Pharmacother. 2011;2:150–157.
  • Chandrasoma PT, Der R, Dalton P, et al. Distribution and significance of epithelial types in columnar-lined esophagus. Am J Surg Pathol. 2001;25:1188–1193.
  • Fitzgerald RC, Omary MB, Triadafilopoulos G. Dynamic effects of acid on Barrett's esophagus. An ex vivo proliferation and differentiation model. J Clin Invest. 1996;98:2120–2128.
  • Sarioglu Y, Yildirim S, Utkan T, Evidence of relaxant effect of omeprazole in rabbit corpus cavernosum in vitro. Life Sci. 2000;66:1411–1421.
  • Yildirim K, Sarioglu Y, Kaya T, Inhibitor effect of omeprazole in isolated human myometrial smooth muscle. Life Sci. 2001;69:435–442.
  • Naseri E, Yenisehirli A. Proton pump inhibitors omeprazole and lansoprazole induce relaxation of isolated human arteries. Eur J Pharmacol. 2006;531:226–231.
  • Bagcivan I, Gokce G, Ayan S, Hydrogen-potassium ATPase inhibitors induce relaxation on rabbit prostatic strips in vitro. Int J Urol. 2002;9:641–644; discussion 645.
  • Yurtsever AS, Pektas M, Ozkur M, Proton pump inhibitors omeprazole, lansoprazole and pantoprazole induce relaxation in the rat lower oesophageal sphincter. J Pharm Pharmacol. 2011;63:1295–1300.
  • Zhao F, Wang J, Yang Y, Effect of CYP2C19 genetic polymorphisms on the efficacy of proton pump inhibitor-based triple therapy for Helicobacter pylori eradication: a meta-analysis. Helicobacter 2008;13:532–541.
  • Pace F, Pallotta S, Casalini S, A review of rabeprazole in the treatment of acid-related diseases. Ther Clin Risk Manag. 2007;3:363–379.

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