Effects of Metoclopramide on Healing of Colonic Anastomoses in a Rat Model of Abdominal Sepsis

REFERENCES

• Wichterman KA, Baue AE, Chaudry IH. Sepsis and septic shock–a review of laboratory models and a proposal. J Surg Res 1980;29:189–201.
   PubMed Web of Science ®Google Scholar
• Ozen IO, Ekingen G, Taslipinar MY, Effect of melatonin on healing of colonic anastomosis in a rat model of peritonitis. Eur Surg Res 2007;39:122–127.
   PubMed Web of Science ®Google Scholar
• Justin-Besançon LLC, Thominet M. Le métoclopramide et sés homologues: introduction à leur étude biologique. C R Acad Sci 1964;258:4384–4386.
   Google Scholar
• Birtley RD, Baines MW. The effects of metoclopramide on some isolated intestinal preparations. Postgrad Med J 1973;49:13–18.
   Web of Science ®Google Scholar
• Okwuasaba FK, Hamilton JT. The effect of metoclopramide on intestinal muscle responses and the peristaltic reflex in vitro. Can J Physiol Pharmacol 1976;54:393–404.
   PubMed Web of Science ®Google Scholar
• Albibi R, McCallum RW. Metoclopramide: pharmacology and clinical application. Ann Intern Med 1983;98:86–95.
   PubMed Web of Science ®Google Scholar
• Thornton FJ, Barbul A. Healing in the gastrointestinal tract. Surg Clin North Am 1997;77:549–573.
   PubMed Web of Science ®Google Scholar
• de Sousa JB, Soares EG, Aprilli F. Effects of diclofenac sodium on intestinal anastomotic healing. Experimental study on the small intestine of rabbits. Dis Colon Rectum 1991;34:613–617.
   PubMed Web of Science ®Google Scholar
• de Oliveira PG, Soares EG, Aprilli F. Influence of misoprostol, a synthetic prostaglandin E1 analog, on the healing of colonic anastomoses in rats. Dis Colon Rectum 1994;37:660–663.
   PubMed Web of Science ®Google Scholar
• Silva SM, Ferreira VM, Feres O, Does metoclopramide impair anastomotic healing of the left colon of rats? Acta Cir Bras 2011;26:297–302.
   PubMed Web of Science ®Google Scholar
• Rittirsch D, Huber-Lang MS, Flierl MA, Immunodesign of experimental sepsis by cecal ligation and puncture. Nat Protoc 2009;4:31–36.
   PubMed Web of Science ®Google Scholar
• Nair SK, Bhat IK, Aurora AL. Role of proteolytic enzyme in the prevention of postoperative intraperitoneal adhesions. Arch Surg 1974;108:849–853.
   PubMedGoogle Scholar
• Tognini JR, Novo NF, Juliano Y. Biomechanical and morphological study in rats’ abdominal wall healing under meloxicam action. Acta Cir Bras 2000;15:146–155.
   Google Scholar
• Junqueira LC, Bignolas G, Brentani RR. Picrosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections. Histochem J 1979;11:447–455.
   PubMedGoogle Scholar
• Stegemann H, Stalder K. Determination of hydroxyproline. Clin Chim Acta 1967;18:267–273.
   PubMed Web of Science ®Google Scholar
• Medugorac I. Collagen content in different areas of normal and hypertrophied rat myocardium. Cardiovasc Res 1980;14:551–554.
   PubMed Web of Science ®Google Scholar
• Platell C, Barwood N, Dorfmann G, The incidence of anastomotic leaks in patients undergoing colorectal surgery. Colorectal Dis 2007;9:71–79.
   PubMed Web of Science ®Google Scholar
• Buchs NC, Gervaz P, Secic M, Incidence, consequences, and risk factors for anastomotic dehiscence after colorectal surgery: a prospective monocentric study. Int J Colorectal Dis 2008;23:265–270.
   PubMed Web of Science ®Google Scholar
• Goligher JC, Graham NG, De Dombal FT. Anastomotic dehiscence after anterior resection of rectum and sigmoid. Br J Surg 1970;57:109–118.
   PubMed Web of Science ®Google Scholar
• Golub R, Golub RW, Cantu R, Jr., A multivariate analysis of factors contributing to leakage of intestinal anastomoses. J Am Coll Surg 1997;184:364–372.
   PubMed Web of Science ®Google Scholar
• Turkcu UO, Cakmak GK, Demir EO, The effect of erythropoietin on anastomotic healing of irradiated rats. J Invest Surg 2012;25:127–135.
   PubMed Web of Science ®Google Scholar
• Demir EO, Cakmak GK, Bakkal H, N-acetyl-cysteine improves anastomotic wound healing after radiotherapy in rats. J Invest Surg 2011;24:151–158.
   PubMed Web of Science ®Google Scholar
• Rocha AA, Leal RF, Ayrizono Mde L, Hyperbaric oxygen therapy and mechanical resistence of the colonics anastomosis in rats with peritonitis. Acta Cir Bras 2010;25:368–374.
   PubMed Web of Science ®Google Scholar
• de Hingh IH, de Man BM, Lomme RM, Colonic anastomotic strength and matrix metalloproteinase activity in an experimental model of bacterial peritonitis. Br J Surg 2003;90:981–988.
   PubMed Web of Science ®Google Scholar
• Teke Z, Sacar S, Yenisey C, Role of activated protein C on wound healing process in left colonic anastomoses in the presence of intra-abdominal sepsis induced by cecal ligation and puncture: an experimental study in the rat. World J Surg 2008;32:2434–2443.
   PubMed Web of Science ®Google Scholar
• Garcia-Olmo D, Paya J, Lucas FJ, The effects of the pharmacological manipulation of postoperative intestinal motility on colonic anastomoses. An experimental study in a rat model. Int J Colorectal Dis 1997;12:73–77.
   PubMed Web of Science ®Google Scholar
• Springall RG, Spitz L. Prevention of post-operative adhesions using a gastrointestinal prokinetic agent. J Ped Surg 1989;6:530–533.
   Google Scholar
• Silva SM, Carneiro FP, Feres O, Effects of bromopride in the anastomoses healing of the left colon of rats. Rev Col Bras Cir 2011;38:249–234.
   Google Scholar
• Silva SM, Carneiro FP, Oliveira PG, Effects of bromopride on the healing of left colonic anastomoses in rats with induced abdominal sepsis. Acta Cir Bras 2012;27:370–375.
   PubMed Web of Science ®Google Scholar
• Liakakos T, Thomakos N, Fine PM, Peritoneal adhesions: etiology, pathophysiology, and clinical significance. Recent advances in prevention and management. Dig Surg 2001;18:260–273.
   PubMed Web of Science ®Google Scholar
• Cahill RA, Wang JH, Redmond H. Enteric bacteria and their antigens may stimulate postoperative peritoneal adhesion formation. Surgery 2007;141:403–410.
   PubMed Web of Science ®Google Scholar
• Beck DE, Cohen Z, Fleshman JW, A prospective, randomized, multicenter, controlled study of the safety of Seprafilm adhesion barrier in abdominopelvic surgery of the intestine. Dis Colon Rectum 2003;46:1310–1319.
   PubMed Web of Science ®Google Scholar
• Garcia-Olmo D, Lucas FJ, Paya J. Relationship between peritoneal adhesion phenomena and the experimental resistance of colonic anastomoses: influence of omentoplasty. Eur Surg Res 1996;28:315–322.
   PubMed Web of Science ®Google Scholar
• Sagar PM, Couse N, Kerin M, Randomized trial of drainage of colorectal anastomosis. Br J Surg 1993;80:769–771.
   PubMed Web of Science ®Google Scholar
• Sparnon AL, Spitz L. Pharmacological manipulation of postoperative intestinal adhesions. Aust N Z J Surg 1989;59:725–729.
   PubMedGoogle Scholar