114
Views
5
CrossRef citations to date
0
Altmetric
ORIGINAL ARTICLE

Ileal Glucose Infusion Leads to Increased Insulin Sensitivity and Decreased Blood Glucose Levels in Wistar Rats

, MD PhD, , MD PhD, , MD PhD, , DVM PhD & , MD PhD
Pages 332-337 | Received 12 Mar 2014, Accepted 27 May 2014, Published online: 24 Jun 2014

REFERENCES

  • Mokdad AH, Bowman BA, Ford ES, The continuing epidemics of obesity and diabetes in the United States. JAMA. 2001;286(10):1195–1200.
  • Sumithran P, Prendergast LA, Delbridge E, Long-term persistence of hormonal adaptations to weight loss. N Engl J Med. 2011;365(17):1597–1604.
  • Cutolo PP, Nosso G, Vitolo G, Clinical efficacy of laparoscopic sleeve gastrectomy vs laparoscopic gastric bypass in obese type 2 diabetic patients: a retrospective comparison. Obes Surg. 2012;22(10):1535–1539.
  • Jimenez A, Casamitjana R, Flores L, Long-term effects of sleeve gastrectomy and Roux-en-Y gastric bypass surgery on type 2 diabetes mellitus in morbidly obese subjects. Ann Surg. 2012;256(6):1023–1029.
  • Peterli R, Steinert RE, Woelnerhanssen B, Metabolic and hormonal changes after laparoscopic Roux-en-Y gastric bypass and sleeve gastrectomy: a randomized, prospective trial. Obes Surg. 2012;22(5):740–748.
  • Foschi D, Corsi F, Colombo F, Different effects of vertical banded gastroplasty and Roux-en-Y gastric bypass on meal inhibition of ghrelin secretion in morbidly obese patients. J Invest Surg. 2008;21(2):77–81.
  • Araujo-Filho I, Rego AC, Azevedo IM, Ileal Interposition and Viability of Pancreatic Islets Transplanted into Intramuscular Site of Diabetic Rats. J Invest Surg. 2013 Dec 30. In press.
  • Rubino F, Gagner M, Gentileschi P, The early effect of the Roux-en-Y gastric bypass on hormones involved in body weight regulation and glucose metabolism. Ann Surg. 2004;240(2):236–242.
  • Rubino F, Marescaux J. Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease. Ann Surg. 2004;239(1):1–11.
  • Sarson DL, Scopinaro N, Bloom SR. Gut hormone changes after jejunoileal (JIB) or biliopancreatic (BPB) bypass surgery for morbid obesity. Int J Obes. 1981;5(5):471–480.
  • Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care. 1999;22(9):1462–1470.
  • Holst JJ. The physiology of glucagon-like peptide 1. Physiol Rev. 2007;87(4):1409–1439.
  • Vella A, Shah P, Basu R, Effect of glucagon-like peptide 1(7–36) amide on glucose effectiveness and insulin action in people with type 2 diabetes. Diabetes. 2000;49(4):611–617.
  • Eissele R, Goke R, Willemer S, Glucagon-like peptide-1 cells in the gastrointestinal tract and pancreas of rat, pig and man. Eur J Clin Invest. 1992;22(4):283–291.
  • Cohen RV, Pinheiro JC, Schiavon CA, Effects of gastric bypass surgery in patients with type 2 diabetes and only mild obesity. Diabetes Care. 2012;35(7):1420–1428.
  • Lee WJ, Chong K, Ser KH, Gastric bypass vs sleeve gastrectomy for type 2 diabetes mellitus: a randomized controlled trial. Arch Surg. 2011;146(2):143–148.
  • Zhu L, Mo Z, Yang X, Effect of laparoscopic Roux-en-Y Gastroenterostomy with BMI < 35 kg/m(2) in type 2 diabetes mellitus. Obes Surg. 2012;22(10):1562–1567.
  • Karra E, Yousseif A, Batterham RL. Mechanisms facilitating weight loss and resolution of type 2 diabetes following bariatric surgery. Trends Endocrinol Metab. 2010;21(6):337–344.
  • Mingrone G, Castagneto-Gissey L. Mechanisms of early improvement/resolution of type 2 diabetes after bariatric surgery. Diabetes Metab. 2009;35(6 Pt 2):518–523.
  • Patriti A, Aisa MC, Annetti C, How the hindgut can cure type 2 diabetes. Ileal transposition improves glucose metabolism and beta-cell function in Goto-kakizaki rats through an enhanced Proglucagon gene expression and L-cell number. Surgery. 2007;142(1):74–85.
  • Rubino F, R'Bibo S L, del Genio F, Metabolic surgery: the role of the gastrointestinal tract in diabetes mellitus. Nat Rev Endocrinol. 2010;6(2):102–109.
  • Rubino F, Gagner M. Potential of surgery for curing type 2 diabetes mellitus. Ann Surg. 2002;236(5):554–559.
  • Mingrone G, DeGaetano A, Greco AV, Reversibility of insulin resistance in obese diabetic patients: role of plasma lipids. Diabetologia. 1997;40(5):599–605.
  • Peterli R, Wolnerhanssen B, Peters T, Improvement in glucose metabolism after bariatric surgery: comparison of laparoscopic Roux-en-Y gastric bypass and laparoscopic sleeve gastrectomy: a prospective randomized trial. Ann Surg. 2009;250(2):234–241.
  • Patel RT, Shukla AP, Ahn SM, Surgical control of obesity and diabetes: the role of intestinal vs. gastric mechanisms in the regulation of body weight and glucose homeostasis. Obesity (Silver Spring). 2014;22(1):159–169.
  • Troy S, Soty M, Ribeiro L, Intestinal gluconeogenesis is a key factor for early metabolic changes after gastric bypass but not after gastric lap-band in mice. Cell Metab. 2008;8(3):201–211.
  • Phillips RJ, Walls EK, Powley TL. Duodenogastric reflux of intestinal infusions in rats is volume dependent. Appetite. 1996;27(1):79–90.
  • Stearns AT, Balakrishnan A, Rhoads DB, Diurnal expression of the rat intestinal sodium-glucose cotransporter 1 (SGLT1) is independent of local luminal factors. Surgery. 2009;145(3):294–302.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.