49
Views
13
CrossRef citations to date
0
Altmetric
Original Article

Perfluorocarbons: Future Clinical Possibilities

, , &
Pages 357-365 | Received 28 Jan 1997, Accepted 23 Sep 1997, Published online: 09 Jul 2009

References

  • Clark L C, Jr, Gollan F. Survival of mammals breathing organic liquids equilibrated with oxygen at atmospheric pressure. Science 1966; 152: 1755–1756
  • Clark L C, Jr. Introduction to fluorocarbons. Int Anesth CI. 1985; 23: 1–9
  • Biro G P. Perfluorocarbon-based red blood cell substitutes. Transfus Med Rev. 1993; 7: 84–95
  • Ohyanagi H, Saitoh Y. Development and clinical application of perfluorochemical artificial blood. Int I Artif Organs 1986; 9: 363–368
  • Marelli T R. Use of a hemoglobin substitute in the anemic Jehovah's witness patient. Crit Care Nurse. 1994; 14(2)31–38
  • Shah N, Mehra A. Modeling of oxygen uptake in perfluorocarbon emulsions. ASAIO J. 1996; 42: 181–189
  • Mitsuno T, Ohyanagi H, Naito R. Clinical studies of a perfluorochemical whole blood substitute (Fluosol-DA). Ann Surg. 1982; 195: 60–69
  • Lowe K C. Perfluorocarbons as oxygen transport fluids. Comp Biochem Physiol 1987; 87A(4)825–838
  • Tremper K K, Friedman A E, Levine E M, Lapin R, Camarillo D. The preoperative treatment of severely anemic patients with a perfluorochemical oxygen-transport fluid, Fluosol-DA. N Engl J Med. 1982; 307: 277–283
  • Tremper K K, Vercellotti G M, Hammerschmidt D E. Hemodynamic profile of adverse clinical reactions to Fluosol-DA 20%. Crit Care Med. 1984; 12: 428–431
  • Waxman K, Tremper K K, Cullen B F, Mason G R. Perfluorocarbon infusion in bleeding patients refusing blood transfusions. Arch Surg. 1984; 119: 721–724
  • Police A M, Waxman K, Tominaga G. Pulmonary complications after Fluosol administration to patients with life-threatening blood loss. Crit Care Med. 1985; 13: 96–98
  • Kale P B, Sklar G E, Wesolowicz L A, DiLisio R E. Fluosol: Therapeutic failure in severe anemia. Ann Pharmacother 1993; 27: 1452–1454
  • Ingram D A, Forman M B, Murray J J. Activation of complement by Fluosol attributable to the pluronic detergent micelle structure. J Cardiovasc Pharmacol. 1993; 22: 456–461
  • Vercellotti G M, Hammerschmidt D E, Craddock P R, Jacob H S. Activation of plasma complement by perfluorocarbon artificial blood: Probable mechanism of adverse pulmonary reactions in treated patients and rationale for cortico-steroid prophylaxis. Blood 1982; 59: 1299–1304
  • Bollands A D, Lowe K C. Effects of a perfluorocarbon emulsion, Fluosol-DA, on rat lymphoid tissue and immunological competence. Comp Biochem Physiol 1986; 85C: 309–312
  • Lowe K C, Washington C. Emulsified perfluorochemicals as respiratory gas carriers: Recovery of perfluorodecalin emulsion droplets from rat tissues. J Pharm Pharmacol. 1993; 45: 938–941
  • Bentley P K, Johnson O L, Washington C, Lowe K C. Uptake of concentrated perfluorocarbon emulsions into rat lymphoid tissues. J Pharm Pharmacol. 1993; 45: 182–185
  • Lau P, Shankar V S, Mayer L L, Wurzel H A, Sloviter. Coagulation defects in rabbits after infusion of dispersed fluoro-chemicals. Transfusion 1975; 15: 432–438
  • Smith D J, Lane T A. Effect of a high concentration perflubron emulsion on platelet function. Biomat Art Cells Immob Biotech. 1993; 21: 173–181
  • Castro O, Nesbitt A E, Lyles D. Effect of a perfluorocarbon emulsion (Fluosol-DA) on reticuloendothelial system clearance function. Am J Hematol. 1984; 16: 15–21
  • Castro O, Reindorf C A, Socha W W, Rowe A W. Perfluorocarbon enhancement of heterologous red cell survival: A reticuloendothelial block effect?. Int Arch Allergy Appl Immunol 1983; 70: 88–91
  • Virmani R, Warren D, Rees R, Fink L M, English D. Effects of perfluorochemical on phagocytic function of leukocytes. Transfusion 1983; 223: 512–515
  • Lane T A, Lamkin G E. Paralysis of phagocyte migration due to an artificial blood substitute. Blood 1984; 64: 400–405
  • Bucala R, Kawakami M, Cerami A. Cytotoxicity of a perfluorocarbon blood substitute to macrophages in vitro. Science 1983; 220: 965–967
  • Kylstra J A, Tissing M O, van der Maen A. Of mice as fish. Trans Am Soc Artif Int Organs 1962; 8: 378–383
  • Schwieler G H, Robertson B. Liquid ventilation in immature newborn rabbits. Biol Neonate. 1976; 29: 343–353
  • Bhutani V K, Shaffer T H. Effect of liquid ventilation of preterm lamb tracheal mechanics. Biol Neonate. 1983; 44: 257–263
  • Greenspan J S, Wolfson M R, Rubenstein S D, Shaffer T H. Liquid ventilation of human preterm neonates. J Pediatr 1990; 117: 106–111
  • Lowe C, Tuma R F, Sivieri E M, Shaffer T H. Liquid ventilation: Cardiovascular adjustments with secondary hyperlactatemia and acidosis. J Appl Physiol. 1979; 47: 1051–1057
  • Curtis S E, Fuhrman B P, Howland D F, De Francisis M, Motoyama E K. Cardiac output during liquid (perfluorocarbon) breathing in newborn piglets. Crit Care Med. 1991; 19: 225–230
  • Degraeuwe P L, Vos G D, Blanco C E. Perfluorochemical liquid ventilation: From the animal laboratory to the intensive care unit. Int J Artif Organs 1995; 18(10)674–683
  • Varani J, Hirschl R B, Dame M, Johnson K. Perfluorocarbon protects lung epithelial cells from neutrophil-mediated injury in an in vitro model of liquid ventilation therapy. Shock. 1996; 6(5)339–344
  • Martin S M, Laks H, Drinkwater D C, Stein D G, Capouya E R, Pearl J M, Barthel S W, Chang P, Kaczer E, Bhuta S. Perfluorochemical reperfusion yields improved myocardial recovery after global ischemia. Ann Thorac Surg. 1993; 55: 954–960
  • Honda K, Motoki R, Hoshino S, Inoue H, UsubaHamada O, Iwaya F, Ando M. Use of perfluorochemical artificial blood (Fluosol-DA) for perfusion of cadaveric kidneys for transplantation. Curr Ther Res. 1980; 28: 309–318
  • Kamada N, Calne R Y, Wight D GD, Lines J G. Orthotopic rat liver transplantation after long-term preservation by continuous perfusion with fluorocarbon emulsion. Transplantation 1980; 30: 43–48
  • Glogar D H, Kloner R A, Muller J, De Boer L WV, Braunwald E. Fluorocarbons reduce myocardial ischemic damage after coronary occlusion. Science 1981; 211: 1439–1441
  • Forman M B, Bingham S, Kopelman H A, Wehr C, Sandler M P, Kolodgie F, Vaughn W K, Friesinger G C, Virmani R. Reduction of infarct size with intracoronary perfluorochemical in a canine preparation of reperfusion. Circulation 1985; 71: 1060–1068
  • Wall T C, Califf R M, Blankenship J, Talley J D, Tannenbaum M, Schwaiger M, Gacioch G, Cohen M D, Sanz M, Leimberger J D, Topol E J. Intravenous fluosol in the treatment of acute myocardial infarction. Circulation 1994; 90: 114–120
  • Sutherland G R, Farrar J K, Peerless S J. The effect of Fluosol-DA on oxygen availability in focal cerebral ischemia. Stroke 1984; 15: 829–835
  • Peerless S J, Nakamura R, Rodriguez-Salazar A, Hunter I G. Modification of cerebral ischemia with fluosol. Stroke 1985; 16: 38–43
  • Peerless S J, Ishikawa R, Hunter I G, Peerless M J. Protective effect of Fluosol-DA in acute cerebral ischemia. Stroke 1981; 12: 558–563
  • Suzuki J, Fujimoto S, Mizoi K, Oba M. The protective effect of combined administration of anti-oxidants and perfluorochemicals on cerebral ischemia. Stroke 1984; 15: 672–679
  • Kent K M, Clemen M W, Cowley M J, Forman M B, Jaffe C C, Kaplan M, King S B, III, Krucoff M W, Lassar T, McAuley B, Smith R, Wisdom C, Wohlgelernter D. Reduction of myocardial ischemia during percutaneous transluminal coronary angioplasty with oxygenated fluosol. Am J Cardiol. 1990; 66: 279–284
  • Virmani R, Kolodgie F D, Osmialowski A, Zimmerman P, Mergner W, Forman M B. Myocardial protection by perfluorochemical infusion during transient ischemia produced by balloon coronary occlusion. Am Heart J. 1988; 116: 421–431
  • Jaffe C C, Wohlgelernter D, Cabin H, Bowman L, Deckelbaum L, Remetz M, Cleman M. Preservation of left ventricular ejection fraction during percutaneous transluminal coronary angioplasty by distal transcatheter coronary perfusion of oxygenated Fluosol DA 20%. Am Heart J. 1988; 115: 1156–1164
  • Klein J, Faithfull N S, Salt P J, Trouwborst A. Transperitoneal oxygenation with fluorocarbons. Anesth Analg. 1986; 65: 734–738
  • Schmidt J A, Bilge F H, Colacino J M, von Recum A F. Peritoneal oxygenation of normoxic and hypoxic dogs. ASAIO Trans. 1989; 35: 35–39
  • Lutz J, Hermann G. Perfluorochemicals as a treatment of decompression sickness in rats. Pflügers Arch. 1984; 401: 174–177
  • Kuwamura K, Kokunai T, Tamaki N, Matsumoto S. Synergistic effect of perfluorochemicals on BCNU chemotherapy. J Neurosurg. 1982; 57: 467–471
  • Klubes P, Hiraga S, Cysyk R L, Owens E S, Blasberg R G. Attempts to increase intratumoral blood flow in the rat solid Walker 256 tumor by the use of the perfluorocarbon emulsion Fluosol-DA. fur J Cancer Clin Oncol. 1987; 23: 1859–1867

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.