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Journal of Investigative Surgery Volume 10, 1997 - Issue 6
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Original Article

Prevention of Adhesion Formation with Intraperitoneal Administration of Tolmetin and Hyaluronic Acid

Kathleen E. Rodgers Livingston Reproductive Biology Laboratory, School of Medicine University of Southern California, Los Angeles, California, USA; Department of Obstetrics and Gynecology, School of Medicine University of Southern California, Los Angeles, California, USA
,
Douglas B. Johns Ethicon, Inc., Somerville, New Jersey, USA
,
Wefki Girgis Livingston Reproductive Biology Laboratory, School of Medicine University of Southern California, Los Angeles, California, USA; Department of Obstetrics and Gynecology, School of Medicine University of Southern California, Los Angeles, California, USA
&
Gere S. Dizerega Livingston Reproductive Biology Laboratory, School of Medicine University of Southern California, Los Angeles, California, USA; Department of Obstetrics and Gynecology, School of Medicine University of Southern California, Los Angeles, California, USA
Pages 367-373 | Received 12 Jun 1996, Accepted 06 Jun 1997, Published online: 09 Jul 2009

References

  • di Zerega G S, Rodgers K E. Intraperitoneal adhesions. The Peritoneum. Springer-Verlag, New York 1992; 274–306
  • Thorton M, di Zerega G S. Using barriers to prevent adhesions. Cont Ob/Gyn. 1996; 41: 107–128
  • Strickler B, Blanco J, Fox H E. The gynecologic contribution to intestinal obstruction in females. J Am Coll Surg. 1994; 178: 617–621
  • Howard F M. The role of laparoscopy in chronic pelvic pain: Promise and pitfalls. Obstet Gynecol Sum 1993; 48: 357–361
  • Peters A AW, Trimbos-Kemper T CM, Admiraal C, et al. A randomized clinical trial on the benefit of adhesiolysis in patients with intraperitoneal adhesions and chronic pelvic pain. Br J Obstet Gynecol. 1992; 99: 59–67
  • De Cherney A H, Mezer H C. The nature of posttuboplasty pelvic adhesions determined by early and late laparoscopy. Fertil Steril. 1984; 41: 643–646
  • Trimbos-Kemper T CM, Trimbos J B, van Hall E V. Adhesion formation after tubal surgery results of the eight-day laparoscopy in 188 patients. Fertil Steril. 1985; 43: 395–400
  • Randall R W, Eakins K E, Higgs G A. Inhibition of arachidonic acid cyclo-oxygenase and lipo-oxygenase activities by indomethacin and compound BW755. Agents Actions 1980; 10: 553–555
  • Nishimura K, Nakamura R M, diZerega G S. Ibuprofen inhibition of postsurgical adhesion formation: A time and dose response biochemical evaluation in rabbits. J Surg Res. 1984; 36: 115–124
  • Rodgers K E, Girgis W, Johns D, di Zerega G S. Intraperitoneal tolmetin prevents postsurgical adhesions formation in rabbits. Int J Infert. 1990; 35: 40–45
  • Rodgers K E, Bracken K, Cox G, Richer L, Girgis W, diZerega G S. Inhibition of post-surgical adhesions by liposomes containing anti-inflammatory drugs. Int J Infert. 1990; 35: 315–320
  • Urman B, Gomel V. Effect of hyaluronic acid on postoperative intraperitoneal adhesion formation and reformation in the rat model. Fertil Steril. 1991; 56: 568–570
  • Urman B, Gomel V. Effect of hyaluronic acid on postoperative intraperitoneal adhesion formation in the rat model. Fertil Steril. 1991; 56: 563–567
  • Rodgers K E. Nonsteroidal anti-inflammatory drugs (NSAIDs) in the treatment of postsurgical adhesions. Treatment of Postsurgical Adhesions, G S diZerega, L R Malinak, M D Diamond, C Linsky. Wiley Liss, New York 1990; 119–129
  • Wiseman D M, Huang W J, Johns D B, Rodgers K E, diZerega G S. Time-dependent effect of tolmetin sodium in a rabbit uterine horn adhesion model. J Invest Surg. 1994; 7: 527–532
  • Le Grand E K, Rodgers K E, Girgis W, Struck K, Campeau J D, diZerega G S, Kiorpes T C. Efficacy of tolmetin sodium for adhesion prevention in rabbit and rat models. J Surg Res. 1994; 56: 67–71
  • Comper W D, Larent T C. Physiologic functions of connective tissue polysaccharides. Physiol Rev. 1978; 4: 255–262
  • Vane J R. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature 1976; 238: 104–107
  • Bonney R J, Davies P. Possible autoregulatory functions of the secretory products of mononuclear phagocytes. Contemp Topics Immunol. 1984; 10: 199–223
  • Rodgers K E, Ellefson D D, Girgis W, Scott L, diZerega G S. Effects of tolmetin sodium dihydrate on normal and post-surgical peritoneal cell function. Int J Immunopharmacol. 1988; 10: 111–120
  • Rodgers K E, Ellefson D D, Girgis W, diZerega G S. Protease and protease inhibitor secretion by postsurgical macro-phages following in vitro exposure to tolmetin. Agents Actions 1992; 36: 248–255
  • Rodgers K E, Ellefson D D, Girgis W, diZerega G S. Modulation of postsurgical cell infiltration and fibrinolytic activity by tolmetin in two species. J Surg Res. 1994; 56: 314–325
  • Abe H, Rodgers K E, Campeau J D, Girgis W, Ellefson D, diZerega G S. The effect of intraperitoneal administration of sodium tolmetin-hyaluronic acid on the postsurgical cell infiltration in vivo. J Surg Res. 1990; 49: 322–327
  • Abe H, Campeau J D, Rodgers K E, Ellefson D D, Girgis W, diZerega G S. Peritoneal lavage fluid protease levels after in vivo administration of tolmetin in hyaluronic acid. J Surg Res. 1993; 55: 1–6
  • Rodgers K E, Abe H, Campeau J D, Ellefson D, Girgis W, diZerega G S. In vivo administration of tolmetin in hyaluronic acid modulates protease levels in post-surgical macrophage conditioned media. J Invest Surg. 1992; 5: 285–291

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