Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 22, 2010 - Issue 3
414
Views
37
CrossRef citations to date
0
Altmetric
Review Article

Cardiopulmonary response to inhalation of biogenic secondary organic aerosol

, , , , , , , , & show all
Pages 253-265 | Received 28 Apr 2009, Accepted 26 Jun 2009, Published online: 12 Feb 2010

References

  • Araujo JA, Barajas B, Kleinman M, Wang X, Bennett BJ, Gong KW, Navab M, Harkema J, Sioutas C, Lusis AJ, Nel AE. 2008. Ambient particulate pollutants in the ultrafine range promote early atherosclerosis and systemic oxidative stress. Circ Res 102:589–596.
  • Baltensperger U, Dommen J, Alfarra MR, Duplissy J, Gaeggeler K, Metzger A, Facchini M C, Decesari S, Finessi E, Reinning C, Schott M, Warnke J, Hoffmann T, Klatzer B, Puxbaum H, Geiser M, Savi M, Lang D, Kalberer M, Geiser T. 2008. Combined determination of the chemical composition and of health effects of secondary organic aerosols: The POLYSOA Project. J Aerosol Med 21:145–154
  • Chow J C, Watson J G, Mauderly J L, Costa D L, Wyzga R E, Vedal S, Hidy G M, Altshuler S L, Marrack D, Heuss J M, Wolff G T, Pope C A III, Dockery DW. 2006. 2006 critical review discussion—Health effects of fine particulate air pollution: Lines that connect. J Air Waste Manage Assoc 56:1368–1380
  • Claeys M, Graham B, Vas G, Wang W, Vermeylen R, Pashynska V, Cafmeyer J, Guyon P, Andreae M O, Artaxo P, Maenhaut W. 2004a. Formation of secondary organic aerosols through photooxidation of isoprene. Science 303:1173–1176
  • Claeys M, Wang W, Ion A C, Kourtchev I, Gelencser A, Maenhaut W. 2004b. Formation of secondary organic aerosols from isoprene and its gas-phase oxidation products through reaction with hydrogen peroxide. Atmos Environ 38:4093–4098
  • Claeys M, Szmigielski R, Kourtchev I, Van der Veken P, Vermeylen R, Maenhuat W, Jaoui M, Kleindienst T E, Lewandowski M, Offenberg J H, Edney E O. 2007. Hydroxydicarboxylic acids: novel markers for secondary organic aerosol from the photooxidation of α-pinene. Environ Sci Technol 41:1628–1634
  • Claeys M, Szmigielski R, Iinuma Y, Surratt J D, Van Alsenoy C, Blockhuys F, Van der Veken Gómez-González Y, Vermeylen R, Shahgholi M, Chan A W H, Herrmann H, Seinfeld J H, Maenhaut W. 2009. Non-covalent dimers from the photooxidation of α-pinene: implications for new particle formation above forests. Science, submitted.
  • Doyle M, Sexton KG, Jeffries H, Bridge K, Jaspers I. 2004. Effects of 13-butadiene isoprene and their photochemical degradation products on human lung cells. Environ Health Perspect 112:1488–1495
  • Doyle M, Sexton KG, Jeffries H, Jaspers I. 2007 Atmospheric photochemical transformations enhance 13-butadiene-induced inflammatory responses in human respiratory epithelial cells: The role of ozone and other photochemical degradation products. Chem Biol Interact 166:163–169.
  • Delfino RJ, Staimer N, Tjoa T, Polidori A, Arhami M, Gillen DL, Kleinman M T, Vaziri N D, Longhurt J, Zaldivar F, Sioutas C. 2008. Circulating biomarkers of inflammation antioxidant activity and platelet activation are associated with primary combustion aerosols in subjects with coronary artery disease. Environ Health Perspect 116(7):898–906
  • Edney E O, Kleindienst T E, Jaoui M, Lewandowski M, Offenberg J H, Wang W, Claeys M. 2005. Formation of 2-methyl tetrols and 2-methylglyceric acid in secondary organic aerosol from laboratory irradiated isoprene/NOx/SO2/air mixtures and their detection in ambient PM25 samples collected in the eastern United States. Atmos Environ 39:5281–5289
  • EPA (US Environmental Protection Agency). 2002. Health Assessment Document for Diesel Engine Exhaust Prepared by the National Center for Environmental Assessment Washington DC for the Office of Transportation and Air Quality; EPA/600/8-90/057F Available from: National Technical Information Service Springfield VA; PB2002-107661 andhttp://wwwepagov/ncea
  • Galloway M M, Chhabra P S, Chan A W H, Surratt J D, Flagan R C, Seinfeld J H, Keutsch F N. 2008. Glyoxal uptake on ammonium sulphate seed aerosol: reaction products and reversibility of uptake under dark and irradiated conditions. Atmos Chem Phys Discuss, submitted.
  • Gao S, Keywood M, Ng N L, Surratt J, Varutbangkul V, Bahreini R, Flagan R C, Seinfeld J H. 2004a. Low-molecular-weight and oligomeric components in secondary organic aerosol from the ozonolysis of cycloalkenes and α-pinene. J Phys Chem A 108:10147–10164
  • Gao S, Ng N L, Keywood M, Varutbangkul V, Bahreini R, Nenes A, He J, Yoo K Y, Beauchamp J L, Hodyss R P, Flagan R C, Seinfeld J H. 2004b. Particle phase acidity and oligomer formation in secondary organic aerosol. Environ Sci Technol 38:6582–6589
  • Gao S, Surratt J D, Knipping E M, Edgerton E S, Shahgholi M, Seinfeld J H. 2006. Characterization of polar organic components in fine aerosols in the southeastern United States: Identity origin and evolution. J Geophys Res 111:D14314.
  • Gómez-González Y, Surratt J D, Cuyckens F, Szmigielski R, Vermeylen R, Jaoui M, Lewandowski M, Offenberg J H, Kleindienst T E, Edney E O, Blockhuys F, Van Alsenoy C, Maenhaut W, Claeys M. 2008. Characterization of organosulfates from the photooxidation of isoprene and unsaturated fatty acids in ambient aerosol using liquid chromatography/(–)electrospray ionization mass spectrometry. J Mass Spectrom 43:371–382
  • Hallquist M, Wenger J C, Baltensperger U, Rudich Y, Simpson D, Claeys M, Dommen J, Donahue N M, George C, Goldstein A H, Hamilton J F, Herrmann H, Hoffmann T, Iinuma Y, Jang M, Jenkin M, Jimenez J-L, Kiendler-Scharr A, Maenhaut W, McFiggans G, Mentel T, Monod A, Prévôt A S H, Seinfeld J H, Surratt J D, Szmigielski R, Wildt J. 2008. The formation properties and impact of secondary organic aerosol: current and emerging issues Atmos Chem Phys Discuss, submitted.
  • Iinuma Y, Böge O, Gnauk T, Herrmann H. 2004. Aerosol-chamber study of the α-pinene/O3 reaction: Influence of particle acidity on aerosol yields and products. Atmos Environ 38:761–773
  • Iinuma Y, Müller C, Böge O, Gnauk T, Herrmann H. 2007a The formation of organic sulfate esters in the limonene ozonolysis secondary organic aerosol (SOA) under acidic conditions. Atmos Environ 41:5571–5583
  • Iinuma Y, Müller C, Berndt T, Böge O, Claeys M, Herrmann H 2007b Evidence for the existence of organosulfates from α-pinene ozonolysis in ambient secondary organic aerosol Environ Sci Technol 41:6678–6683
  • Jang M S, Czoschke N M, Lee S, Kamens R M. 2002. Heterogeneous atmospheric aerosol production by acid-catalyzed particle-phase reactions. Science 298;814–817
  • Jang M, Ghio A, Gang C. 2006. Exposure of BEAS-2B cells to secondary organic aerosol coated on magnetic nanoparticles. Chem Res Toxicol 19:1044–1050
  • Jaoui M, Kleindienst T E, Lewandowski M, Offenberg J H, Edney E O. 2005. Identification and quantification of aerosol polar oxygenated compounds bearing carboxylic or hydroxyl groups: 2 organic tracer compounds from monoterpenes. Environ Sci Technol 39:5661–5673
  • Kanakidou M, Seinfeld J H, Pandis S N, Barnes I, Dentener F J, Facchini M C, Van Dingenen R, Ervens B, Nenes A, Nielsen C J, Swietlicki E, Putaud J P, Balkanski Y, Fuzzi S, Horth J, Moortgat G K, Winterhalter R, Myhre C E L, Tsigaridis K, Vignati E, Stephanou E G, Wilson J. 2005. Organic aerosol and global climate modeling: A review. Atmos Chem Phys 5:1053–1123
  • Kleindienst T E, Conver T S, McIver C D, Edney E O. 2004. Determination of secondary organic aerosol products from the photooxidation of toluene and their implications in ambient PM25. J Atmos Chem 47:79–100
  • Kleindienst T E, Edney E O, Lewandowski M, Offenberg J H, Jaoui M. 2006. Secondary organic carbon and aerosol yields from the irradiations of isoprene and α-pinene in the presence of NOx and SO2. Environ Sci Technol 40:3807–3812
  • Kourtchev I, Ruuskanen T M, Keronen P, Sogacheva L, Dal Maso M, Reissell A, Chi X, Vermeylen R, Kulmala M, Maenhaut W, Claeys M. 2008a. Determination of isoprene and α-/β-pinene oxidation products in boreal forest aerosols from Hyytiälä Finland: Diel variations and possible link with particle formation events. Plant Biol 10:138–149
  • Kourtchev I, Warnke J, Maenhaut W, Hoffmann T, Claeys M. 2008b. Polar organic marker compounds in PM25 aerosol from a mixed forest site in Western Germany Chemosphere 73:1308–1314
  • Kroll J H, Ng N L, Murphy S M, Flagan R C, Seinfeld J H. 2006. Secondary organic aerosol formation from isoprene photooxidation. Environ Sci Technol 40:1869–1877
  • Kroll J H, Seinfeld J H. 2008. Chemistry of secondary organic aerosol: formation and evolution of low-volatility organics in the atmosphere. Atmos Environ 42:3593–3624
  • Larsen B R, Di Bella D, Glasius M, Winterhalter R, Jensen N R, Hjorth J. 2001. Gas-phase OH oxidation of monoterpenes: Gaseous and particulate products. J Atmos Chem 38:231–276
  • Lewandowski M, Jaoui M, Kleindienst T E, Offenberg J H, Edney E O. 2007. Composition of PM25 during the summer of 2003 in Research Triangle Park, North Carolina. Atmos Environ 41:4073–4083
  • Lund A K, Knuckles T L, Obot Akata C, Shohet R, McDonald JD, Gigliotti A, Seagrave JC, Campen M J. 2007. Gasoline exhaust emissions induce vascular remodeling pathways involved in atherosclerosis. Toxicol Sci 95:485–494
  • Lund A K, Lucero J A, Lucas S, Madden M C, McDonald J D, Seagrave J C, Knuckles T L, Campen M J. 2009. Vehicular emissions induce vascular MMP-9 expression and activity via endothelin-1 mediated pathways. Arterioscler Thromb Vasc Biol 29:511–517
  • Mauderly J L, Chow J C. 2008. Health effects of organic aerosols. Inhal Toxicol 20:257–288
  • McDonald J D, Barr E B, White R K, Chow J C, Schauer J J, Zielinska B, Grosjean E. 2004. Generation and characterization of four dilutions of diesel engine exhaust for a subchronic inhalation study. Environ Sci Technol 38(9):2513–2522
  • McDonald J D, White R K, Barr E B, Zielinska B, Chow J C E, Grosjean E. 2006. Generation and characterization of hardwood smoke inhalation exposure atmospheres. Aerosol Sci Technol 40:573–584
  • McDonald J D, Reed M D, Campen M J, Barrett E G, Seagrave J, Mauderly J L. 2007. Health effects of inhaled gasoline engine emissions. Inhal Toxicol 19(Suppl 1):107-116
  • McDonald J D, Barr E B, White R K, Kracko D, Chow J C, Zielinska B, Grosjean E. 2008. Generation and characterization of gasoline engine exhaust inhalation exposure atmospheres. Inhal Toxicol 20:1157–1168
  • Nawrot T S, Torfs R, Fierens F, de Henauw S, Hoet P H, van Kersschaever G, de Backer G, Nemery B. 2007. Stronger associations between daily mortality and fine particulate air pollution in summer than in winter: evidence from a heavily polluted region in Western Europe. J Epidemiol Community Health 61:146–149
  • Ng N L, Chhabra P S, Chan A W H, Surratt J D, Kroll J H, Kwan A J, McCabe D C, Wennberg P O, Sorooshian A, Murphy S M, Dalleska N F, Flagan R C, Seinfeld J H. 2007. Effect of NOx level on secondary organic aerosol (SOA) formation from the photooxidation of terpenes. Atmos Chem Phys 7:5159–5174
  • Pope CA III, Dockery DW. 2006. Health effects of fine particulate air pollution: Lines that connect. J Air Waste Manage Assoc 56:709–742
  • Reed M D, Blair L F, Burling K, Daly I, Gigliotti A P, Gudi R, Mercieca M D, McDonald J D, O’Callaghan J P, Seilkop S K, Ronsko N L, Wagner V O, Kraska R C. 2006. Health effects of subchronic exposure to diesel-water-methanol emulsion emissions. Toxicol Ind Health 22:65–85
  • Reemtsma T, These A, Venkatachari P, Xia X Y, Hopke P K, Springer A, Linscheid M. 2006. Identification of fulvic acids and sulfated and nitrated analogues in atmospheric aerosol by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry. Anal Chem 78:8299–8304
  • Reiss R, Anderson E L, Cross C E, Hidy G, Hoel D, McClellan R, Moolgavkar S. 2007. Evidence of health impacts of sulfate- and nitrate-containing particles in ambient air. Inhal Toxicol 19:419–449
  • Rhoden C R, Lawrence J, Godleski J J, Gonzalez-Flecha B. 2004. N-acetylcysteine prevents lung inflammation after short-term inhalation exposure to concentrated ambient particles. Toxicol Sci 79:296–303
  • Rohr A C, Wilkins C K, Clausen P A, Hammer M, Nielsen GD, Wolkoff P, Spengler JD. 2002. Upper airway and pulmonary effects of oxidation products of (+)-α-pinene d-limonene and isoprene in BALB/c mice. Inhal Toxicol 14:663–684
  • Romero F, Oehme M. 2005. Organosulfates—a new component of humic-like substances in atmospheric aerosols? J Atmos Chem 52:283–294
  • Ruiz PA, Gupta T, Kang C-M, Lawrence JE, Ferguson ST, Wolkson JM, Rohr AC, Koutrakis P. 2007. Development of an exposure system for the toxicological evaluation of particles derived from coal-fired power plants. Inhal Toxicol 19:607–619
  • Schlesinger R B. 2007. The health impact of common inorganic components of fine particulate matter (PM25) in ambient air: A critical review. Inhal Toxicol 19:811–832
  • Seagrave J, McDonald J D, Bedrick E, Edgerton E S, Gigliotti A P, Jansen J J, Ke L, Naeher L P, Seilkop S K, Zheng M, Mauderly J L. 2006. Lung toxicity of ambient particulate matter from southeastern US sites with different contributing sources: Relationships between composition and effects. Environ Health Perspect 114:1387–1393
  • Seagrave JC, Campen M J, McDonald J D, Mauderly J L, Rohr A C. 2008. Oxidative stress inflammation and pulmonary function assessment in rats exposed to laboratory-generated pollutant mixtures. J Toxicol Environ Health A 17:1352–1362
  • Sexton K G, Jeffries H E, Jang M, Kamens R M, Doyle M, Voicu I, Jaspers I. 2004. Photochemical products in urban mixtures enhance inflammatory responses in lung cells. Inhal Toxicol 16(Suppl 1):107–114
  • Sunil V R, Laumbach R J, Patel K J, Turpin B J, Lim H-J, Kipen H M, Laskin J D, Laskin D L. 2007. Pulmonary effects of inhaled limonene ozone reaction products in elderly rats. Toxicol Appl Pharmacol 222:211–220
  • Surratt J D, Murphy S M, Kroll J H, Ng N L, Hildebrandt L, Sorooshian A, Szmigielski R, Vermeylen R, Maenhaut W, Claeys M, Flagan R C, Seinfeld J H. 2006. Chemical composition of secondary organic aerosol formed from the photooxidation of isoprene. J Phys Chem A 110:9665–9690
  • Surratt J D, Kroll J H, Kleindienst T E, Edney E O, Claeys M, Sorooshian A, Ng N L, Offenberg J H, Lewandowski M, Jaoui M, Flagan R C, Seinfeld J H. 2007a. Evidence for organosulfates in secondary organic aerosol. Environ Sci Technol 41:517–527
  • Surratt J D, Lewandowski M, Offenberg J H, Jaoui M, Kleindienst T E, Edney E O, Seinfeld J H. 2007b. Effect of acidity on secondary organic aerosol formation from isoprene. Environ Sci Technol 41:5363–5369
  • Surratt J D, Gómez-González Y, Chan A W H, Vermeylen R, Shahgholi M, Kleindienst T E, Edney E O, Offenberg J H, Lewandowski M, Jaoui M, Maenhaut W, Claeys M, Flagan R C, Seinfeld J H. 2008. Organosulfate formation in biogenic secondary organic aerosol. J Phys Chem A 112:8345–8378
  • Szmigielski R, Surratt J D, Gómez-González Y, Van der Veken P, Kourtchev I, Vermeylen R, Blockhuys F, Jaoui M, Kleindienst T E, Lewandowski M, Offenberg J H, Edney E O, Seinfeld J H, Maenhaut W, Claeys M. 2007. 3-Methyl-123-butanetricarboxylic acid: An atmospheric tracer for terpene secondary organic aerosol. Geophys Res Lett 34:L24811.
  • Wang W, Vas G, Dommisse R, Loones K, Claeys M. 2004. Fragmentation study of diastereoisomeric 2-methyltetrols oxidation products of isoprene as their trimethylsilyl ethers using gas chromatography/ion trap mass spectrometry. Rapid Commun Mass Spectrom 18:1787–1797
  • Wang W, Kourtchev I, Graham B, Cafmeyer J, Maenhaut W, Claeys M. 2005. Characterization of oxygenated derivatives of isoprene related to 2-methyltetrols in Amazonian aerosols using trimethylsilylation and gas chromatography/ion trap mass spectrometry. Rapid Commun Mass Spectrom 19:1343–1351
  • Warscheid B, Hoffmann T. Direct analysis of highly oxidized organic aerosol constituents by on-line ion trap mass spectrometry in the negative-ion mode. Rapid Commun Mass Spectrom 16:496–504.
  • Wilkins CK, Clausen PA, Wolkoff P, Larsen ST, Hammer M, Larsen K, Hansen V, Nielsen GD. 2001. Formation of strong airway irritants in mixtures of isoprene/ozone and isoprene/ozone/nitrogen dioxide. Environ Health Perspect 109:937–941
  • Wolkoff P, Clausen PA, Larsen K, Hammer M, Larsen ST, Nielsen GD. 2008. Acute airway effects of ozone-initiated d-limonene chemistry: Importance of gaseous products. Toxicol Lett 181:171–176
  • Zhang SH, Reddick RL, Piedrahita JA, Maeda N. 1992. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 258:468–471
  • Zielinska B, McDonald J, Seagrave J. 2008. Atmospheric transformation of diesel emissions. Final report. Submitted to the Health Effects Institute.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.