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Inhalation Toxicology
International Forum for Respiratory Research
Volume 22, 2010 - Issue 7
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Research Article

Changes in biologic and/or immunologic parameters induced by intratracheal instillation of pregnant mice with benzo(α)pyrene are potentially confounded by anesthesia

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Pages 571-579 | Received 03 Sep 2009, Accepted 04 Jan 2010, Published online: 13 Apr 2010

References

  • Alleva R, Tomasetti M, Solenghi M. D, Stagni F, Gamberini F, Bassi A, Fornasari PM, Fanelli G, Borghi B. 2003. Lymphocyte DNA damage precedes DNA repair or cell death after orthopaedic surgery under general anaesthesia. Mutagenesis 18:423–428.
  • Anderson LM, Ruskie S, Carter J, Pittinger S, Kovatch RM, Riggs CW. 1995. Fetal mouse susceptibility to transplacental carcinogenesis: Differential influence of Ah receptor phenotype on effects of 3-methylcholanthrene, 12-dimethylbenz[a]anthracene, and benzo[a]pyrene. Pharmacogenetics 5:364–372.
  • ATSDR. 2008. Agency for Toxic Substances and Disease Registry. Case Studies in Environmental Medicine (CSEM): Toxicity of Polycyclic Aromatic Hydrocarbons (PAHs)—What Are the Routes of Exposure for PAHs. Atlanta, GA : ATSDR.
  • Boucher BA, Witt WO, Foster TS. 1986. The post-operative adverse effects of inhalational anesthetics. Heart Lung 15:63–69.
  • Bovill JG. 2008. Inhalation anaesthesia: From diethyl ether to xenon. Handbook Exp Pharmacol 182:121–142.
  • Bulay OM, Wattenberg LW. 1971. Carcinogenic effects of PAH carcinogen administration to mice during pregnancy on their progeny. J Natl Cancer Inst 46:397–402.
  • Buters JT, Mahadevan B, Quintanilla-Martinez I, Gonzalez FJ, Greim H, Baird WM, Luch A. 2002. Cytochrome P450 1B1 determines susceptibility to dibenzo(a,1)pyrene-induced tumor formation. Chem Res Toxicol 15:1127–1135.
  • Carcinogenic Potency Project. 2007. Oil corn (CAS 8001-30-7). Available at: http://potency.berkeley.edu/chempages/OIL%20CORN.html
  • Castro DJ, Lohr CV, Fischer KA, Pereira CB, Williams DE. 2008. Lymphoma and lung cancer in offspring born to pregnant mice dosed with dibenzo[a,l]pyrene: The importance of in utero vs. lactational exposure. Toxicol Appl Pharmacol 233:454–458.
  • Castro DJ, Lohr CV, Fischer KA, Waters KM, Webb-Robertson BJ, Dashwood RH, Bailey GS, Williams DE. 2009. Identifying efficacious approaches to chemoprevention with chlorophyllin purified chlorophylls and freeze-dried spinach in a mouse model of transplacental carcinogenesis. Carcinogenesis 30:315–320.
  • CDC. 2005. Centers for Disease Control and Prevention. Third National Report on Human Exposure to Environmental Chemicals. Atlanta, GA: CDC.
  • Dean EA, Luster MI, Boorman GA, Lauer LD, Luebke RW, Lawson ID. 1983. Immune suppression following exposure of mice to the carcinogen but not to the non-carcinogenic benzo(e)pyrene. Clin Exp Toxicol 52:199–206.
  • Eger EI, White AE, Brown CL, Biava CG, Corbett TH, Stevens WC. 1978. A test of the carcinogenicity of enflurane, isoflurane, halothane, methoxyflurane, and nitrous oxide in mice. Anesth Analg 57:678–694.
  • Feng Y, Shi G, Wu J, Wang Y, Zhu T, Dai S, Pei Y. 2007. Source analysis of particulate-phase polycyclic aromatic hydrocarbons in an urban atmosphere of a northern city in China. J Air Waste Manage Assoc 57:164–171.
  • Holladay SD, Smith BJ. 1994. Fetal hematopoietic alterations after maternal exposure to B(α)P: A cytometric evaluation. J Toxicol Environ Health 42:259–273.
  • Irwin MG, Trinh T, Yao CL. 2009. Occupational exposure to anaesthetic gases: A role for TIVA. Exp Opin Drug Saf 8:473–483.
  • Lu LJ, Wang MY. 1990. Modulation of B(α)P-induced covalent DNA modifications in adult and fetal mouse tissues by gestation stage. Carcinogenesis 11:1367–1372.
  • Malmgren RA, Bennison BE, McKinley TW Jr. 1952. Reduced antibody titers in mice treated with carcinogenic and cancer chemotherapeutic agents. Proc Soc Exp Biol Med 79:484–488.
  • Moolenaar-Wirsiy PJ, Wirsiy YG, Urso P. 2007. Presence of CD4+ SP and DP (γδ, αβ) T-cells expressing BPDE-DNA adducts in progeny of mouse dams exposed to B(α)P at mid-gestation. J Immuntoxicol 4:267–277.
  • MVP (Medical Developments International). 2006. http://www.medicaldev.com/pdf_files/ Investor_Relations_ASX_Announcements/ASX_Release_Finalises_agreement_with_Schering_Plough_for_US_Vet_Licence.pdf.
  • Nettesheim P, Cresia DA, Mitchell TJ. 1975. Carcinogenic and carcinogenesis effects of inhaled synthetic smog and ferric oxide particles. J Natl Cancer Inst 55:159–169.
  • Nikinova TV. 1977. Placental action of benzo(a)pyrene and pyrene. Bull Eksp Biol Med 84:21025–19027.
  • Peck AB, Bach FH. 1973. A miniaturized mouse mixed lymphocyte culture in serum-free and mouse serum-supplemented media. J Immunol Methods 3:147–164.
  • Reitz M, Antonini-Rumpf E, Lanz E. 1993. DNA single strand breaks in peripheral human lymphocytes after anesthesia with isoflurane-nitrous oxide-oxygen. Arzn Forsch 43:1258–1261.
  • Reitz M, Coen R, Lanz E. 1994. DNA single-strand breaks in peripheral lymphocytes of clinical personnel with occupational exposure to volatile inhalational anesthetics. Environ Res 65:12–21.
  • Reitz M, Das Gupta K, Lober G, Kleemann P. 1998. Variations of DNA damage in human lymphocytes after enflurane exposure in vitro. Arzn Forsch 48:120–124.
  • Rodriguez JW, Kirlin WG, Wirsiy YG, Matheravidathu S, Hodge TW, Urso P. 1999. Maternal exposure to B(α)P alters development of T-lymphocytes in offspring. Immunopharmacol Immunotoxicol 21:379–396.
  • Rozgaj R, Kasuba V, Jazbec A. 2001. Preliminary study of cytogenetic damage in personnel exposed to anesthetic gases. Mutagenesis 16:139–143.
  • Sardas S, Aygun N, Gamli M, Unal Y, Unal N, Berk N, Karakaya AE. 1998a. Use of alkaline comet assay (single cell gel electrophoresis technique) to detect DNA damages in lymphocytes of operating room personnel occupationally exposed to anaesthetic gases. Mutat Res 418:93–100.
  • Sardas S, Karabiyik L, Aygun N, Karakaya AE. 1998b. DNA damage evaluated by the alkaline comet assay in lymphocytes of humans anaesthetized with isoflurane. Mutat Res 418:1–6.
  • Schnizlein CT, Munson AE, Rhoades RA. 1987. Immunomodulation of local and systemic immunity after subchronic pulmonary exposure of mice to B(α)P. Int J Immunopharmacol 9:99–106.
  • Searle CE. 1984. Chemical Carcinogens. Washington, DC: American Chemical Society, 51–501.
  • Slade MS, Simmons RL, Yunis E, Greenberg LJ. 1975. Immunodepression after major surgery in normal patients. Surgery 78:363–372.
  • Saffiotti U, Cefis F, Kola LH. 1968. A method for the experimental induction of bronchiogenic carcinoma. Cancer Res 28:104–124.
  • Sjaastad AK, Svendsen K. 2009. Exposure to polycyclicaromatic hydrocarbons (PAHs), mutagenic aldehydes, and particulate matter in Norwegian à la carte restaurants. Ann Occup Hyg 53:723–729.
  • Tomatis L, Turusov V, Gulbbert D, Duperray B, Malaveille C, Pacheco H. 1971. Transplacental carcinogenic effect of 3-methylcholanthrene in mice and its quantitation in fetal tissues. J Natl Cancer Inst 47:645–651.
  • Urso P, Gengozian N. 1980. Depressed humoral immunity and increased tumor incidence in mice following in utero exposure to B(α)P. J Toxicol Environ Health 6:569–576.
  • Urso P, Gengozian N. 1984. Subnormal expression of cell-mediated and humoral immune response in progeny disposed toward a high incidence of tumors after in utero exposure to B(α)P. J Toxicol Environ Health 214:569–584.
  • Urso P, Johnson RA. 1987. Early changes in T-lymphocytes and subsets of mouse progeny defective as adults in controlling growth of a syngeneic tumor after in utero insult with B(α)P. Immunopharmacology 14:1–10.
  • Urso P, Johnson RA. 1988. Quantitative and functional change in T-cells of primiparous mice following injection of B(α)P at the second trimester of pregnancy. Immunopharmacol Immunotoxicol 10:195–217.
  • Urso P, Zhang W, Cobb JR. 1992. Immunological consequences from exposure to B(α)P during pregnancy. Scand J Immunol 36(S11):203–211.
  • Urso P, Wirsiy Y, Zhang W, Rodriguez J, Moolenaar P. 1994. Persistent defective T-cell differentiation in mice exposed to benzo(α)pyrene in utero. FASEB J 54:A482.
  • Urso P, Wirsiy YG, Zhang W, Moolenaar-Wirsiy PJ. 2008. Alterations in CD4+, CD8+, Vγ3, Vγδ, and/or Vαβ T-lymphocyte expression in lymphoid tissues of progeny after in utero exposure to B(α)P. J Immunotoxicol 5:293–306.
  • Wang MY, Lu LJ. Differential effect of gestation stage on B(α)P-induced micronucleus formation and/or covalent DNA modifications in mice. Cancer Res 50:2146–2151.
  • Waymack JP, Miskell P, Gonce S. 1989. Alterations in host defense associated with inhalation anesthesia and blood transfusion. Anesth Analg 69:163–168.
  • Welling P, Kaandorp B. 1986. Determination of polycyclic aromatic hydrocarbons (PAH) in edible vegetable oils by liquid chromatography and programmed fluorescence detection. Z Lebensm Unters Forsch 183:111–115.
  • Wojdani A, Nieto M, Alfred LJ. 1983. Carcinogenic PAH compound suppressed cell-mediated immune functions, and alter T-cell subsets in splenic lymphocyte populations. Proc Am Assoc Cancer Res 24:242–250.
  • Wolisi GO, Majekodunmi J, Bailey GB, Urso P. 2001. Immunomodulation in progeny from thymectomized primiparous mice exposed to B(α)P during mid-pregnancy. Immunopharmacol. Immunotoxicol 23:267–280.
  • Zhang L, Bai Z, You Y, Wu J, Feng Y, Zhu T. 2009. Chemical and stable carbon isotopic characterization for PAHs in aerosol emitted from two indoor sources. Chemosphere 75:453–461.

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