The role of cardiovascular disease-associated iron overload in Libby amphibole-induced acute pulmonary injury and inflammation

References

• Adamson IY, Bakowska J. 2001. KGF and HGF are growth factors for mesothelial cells in pleural lavage fluid after intratracheal asbestos. Exp Lung Res 27:605–616.
   PubMed Web of Science ®Google Scholar
• Anderson GJ, Vulpe CD. 2009. Mammalian iron transport. Cell Mol Life Sci 66:3241–3261.
   PubMed Web of Science ®Google Scholar
• Anderson ME. 1985. Determination of glutathione and glutathione disulfide in biological samples. Meth Enzymol 113:548–555.
   PubMed Web of Science ®Google Scholar
• Driscoll KE, Carter JM, Howard BW, Hassenbein D, Janssen YM, Mossman BT. 1998. Crocidolite activates NF-kappa B and MIP-2 gene expression in rat alveolar epithelial cells. Role of mitochondrial-derived oxidants. Environ Health Perspect 106(Suppl 5):1171–1174.
   PubMed Web of Science ®Google Scholar
• Dorger M, Allmeling AM, Kiefmann R, Munzing S, Messmer K, Krombach F. 2002. Early inflammatory response to asbestos exposure in rat and hamster lungs: Role of inducible nitric oxide synthase. Toxicol Appl Pharmacol 181:93–105.
   PubMed Web of Science ®Google Scholar
• Dostert C, Pétrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J. 2008. Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 320:674–677.
   PubMed Web of Science ®Google Scholar
• Duncan KE, Ghio AJ, Dailey LA, Bern AM, Gibbs-Flournoy EA, Padilla-Carlin DJ, Roggli VL, Devlin RB. 2010. Effect of size fractionation on the toxicity of amosite and Libby amphibole asbestos. Toxicol Sci 118:420–434.
   PubMed Web of Science ®Google Scholar
• Ellervik C, Tybjaerg-Hansen A, Appleyard M, Ibsen H, Nordestgaard BG. 2010. Haemochromatosis genotype and iron overload: association with hypertension and left ventricular hypertrophy. J Intern Med 268:252–264.
   PubMed Web of Science ®Google Scholar
• Fattman CL, Tan RJ, Tobolewski JM, Oury TD. 2006. Increased sensitivity to asbestos-induced lung injury in mice lacking extracellular superoxide dismutase. Free Radic Biol Med 40:601–607.
   PubMed Web of Science ®Google Scholar
• Gazzano E, Turci F, Foresti E, Putzu MG, Aldieri E, Silvagno F, Lesci IG, Tomatis M, Riganti C, Romano C, Fubini B, Roveri N, Ghigo D. 2007a. Iron-loaded synthetic chrysotile: a new model solid for studying the role of iron in asbestos toxicity. Chem Res Toxicol 20:380–387.
   PubMed Web of Science ®Google Scholar
• Ghio AJ, Carter JD, Richards JH, Brighton LE, Lay JC, Devlin RB. 1998. Disruption of normal iron homeostasis after bronchial instillation of an iron-containing particle. Am J Physiol 274:L396–L403.
   Google Scholar
• Ghio AJ, Roggli VL, Richards JH, Crissman KM, Stonehuerner JD, Piantadosi CA. 2003. Oxalate deposition on asbestos bodies. Hum Pathol 34:737–742.
   PubMed Web of Science ®Google Scholar
• Ghio AJ, Churg A, Roggli VL. 2004. Ferruginous bodies: implications in the mechanism of fiber and particle toxicity. Toxicol Pathol 32:643–649.
   PubMed Web of Science ®Google Scholar
• Ghio AJ, Funkhouser W, Pugh CB, Winters S, Stonehuerner JG, Mahar AM, Roggli VL. 2006. Pulmonary fibrosis and ferruginous bodies associated with exposure to synthetic fibers. Toxicol Pathol 34:723–729.
   PubMed Web of Science ®Google Scholar
• Ghio AJ, Stonehuerner J, Richards J, Devlin RB. 2008. Iron homeostasis in the lung following asbestos exposure. Antioxid Redox Signal 10:371–377.
   PubMed Web of Science ®Google Scholar
• Governa M, Amati M, Fontana S, Visona I, Botta GC, Mollo F, Bellis D, Bo P. 1999. Role of iron in asbestos-body-induced oxidant radical generation. J Toxicol Environ Health Part A 58:279–287.
   PubMed Web of Science ®Google Scholar
• Gozzelino R, Jeney V, Soares MP. 2010. Mechanisms of cell protection by heme oxygenase-1. Annu Rev Pharmacol Toxicol 50:323–354.
   PubMed Web of Science ®Google Scholar
• Hill GD, Mangum JB, Moss OR, Everitt JI. 2003. Soluble ICAM-1, MCP-1, and MIP-2 protein secretion by rat pleural mesothelial cells following exposure to amosite asbestos. Exp Lung Res 29:277–290.
   PubMed Web of Science ®Google Scholar
• Hirano S, Ono M, Aimoto A. 1988. Functional and biochemical effects on rat lung following instillation of crocidolite and chrysotile asbestos. J Toxicol Environ Health 24:27–39.
   PubMed Web of Science ®Google Scholar
• Kamp DW, Israbian VA, Preusen SE, Zhang CX, Weitzman SA. 1995a. Asbestos causes DNA strand breaks in cultured pulmonary epithelial cells: role of iron-catalyzed free radicals. Am J Physiol 268:L471–L480.
   PubMed Web of Science ®Google Scholar
• Kamp DW, Israbian VA, Yeldandi AV, Panos RJ, Graceffa P, Weitzman SA. 1995b. Phytic acid, an iron chelator, attenuates pulmonary inflammation and fibrosis in rats after intratracheal instillation of asbestos. Toxicol Pathol 23:689–695.
   PubMed Web of Science ®Google Scholar
• Kamp DW, Weitzman SA. 1999. The molecular basis of asbestos induced lung injury. Thorax 54:638–652.
   PubMed Web of Science ®Google Scholar
• Kapturczak MH, Wasserfall C, Brusko T, Campbell-Thompson M, Ellis TM, Atkinson MA, Agarwal A. 2004. Heme oxygenase-1 modulates early inflammatory responses: evidence from the heme oxygenase-1-deficient mouse. Am J Pathol 165:1045–1053.
   PubMed Web of Science ®Google Scholar
• Kibel A, Belovari T, Drenjancevic-Peric I. 2008. The role of transferrin in atherosclerosis. Med Hypotheses 70:793–797.
   PubMed Web of Science ®Google Scholar
• Koorts AM, Viljoen M. 2007. Ferritin and ferritin isoforms I: Structure-function relationships, synthesis, degradation and secretion. Arch Physiol Biochem 113:30–54.
   PubMedGoogle Scholar
• Kruszewski M. 2004. The role of labile iron pool in cardiovascular diseases. Acta Biochim Pol 51:471–480.
   PubMed Web of Science ®Google Scholar
• Lowers HA, Bern AM. 2009. Particle Size Characterization of Water-Elutriated Libby Amphibole 2000 and RTI International Amosite. USGS Open File Report 2009–1242.
   Google Scholar
• Meeker GP, Bern AM, Brownfield IK, Lowers HA, Sutley SJ, Hoefen TM, Vance JS. 2003. The composition and morphology of amphiboles from the Rainy Creek Complex, near Libby, Montana. American Mineralogist 88:1955–1969.
   Web of Science ®Google Scholar
• Nyska A, Murphy E, Foley JF, Collins BJ, Petranka J, Howden R, Hanlon P, Dunnick JK. 2005. Acute hemorrhagic myocardial necrosis and sudden death of rats exposed to a combination of ephedrine and caffeine. Toxicol Sci 83:388–396.
   PubMed Web of Science ®Google Scholar
• Peipins LA, Lewin M, Campolucci S, Lybarger JA, Miller A, Middleton D, Weis C, Spence M, Black B, Kapil V. 2003. Radiographic abnormalities and exposure to asbestos-contaminated vermiculite in the community of Libby, Montana, USA. Environ Health Perspect 111:1753–1759.
   PubMed Web of Science ®Google Scholar
• Poss KD, Tonegawa S. 1997. Reduced stress defense in heme oxygenase 1-deficient cells. Proc Natl Acad Sci USA 94:10925–10930.
   PubMed Web of Science ®Google Scholar
• Putnam EA, Smartt A, Groves A, Schwanke C, Brezinski M, Pershouse MA. 2008. Gene expression changes after exposure to six-mix in a mouse model. J Immunotoxicol 5:139–144.
   PubMed Web of Science ®Google Scholar
• Raval CM, Lee PJ. 2010. Heme oxygenase-1 in lung disease. Curr Drug Targets 11:1532–1540.
   PubMed Web of Science ®Google Scholar
• Sabo-Attwood T, Ramos-Nino M, Bond J, Butnor KJ, Heintz N, Gruber AD, Steele C, Taatjes DJ, Vacek P, Mossman BT. 2005. Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis. Am J Pathol 167:1243–1256.
   PubMed Web of Science ®Google Scholar
• Sanchez VC, Pietruska JR, Miselis NR, Hurt RH, Kane AB. 2009. Biopersistence and potential adverse health impacts of fibrous nanomaterials: what have we learned from asbestos? Wiley Interdiscip Rev Nanomed Nanobiotechnol 1:511–529.
   PubMed Web of Science ®Google Scholar
• Shackelford C, Long G, Wolf J, Okerberg C, Herbert R. 2002. Qualitative and quantitative analysis of nonneoplastic lesions in toxicology studies. Toxicol Pathol 30:93–96.
   PubMed Web of Science ®Google Scholar
• Shannahan JH, Schladweiler MC, Richards JH, Ledbetter AD, Ghio AJ, Kodavanti UP. 2010. Pulmonary oxidative stress, inflammation, and dysregulated iron homeostasis in rat models of cardiovascular disease. J Toxicol Environ Health Part A 73:641–656.
   PubMed Web of Science ®Google Scholar
• Shannahan JH, Ghio AJ, Schladweiler MC, McGee JK, Richards JH, Gavett SH, Kodavanti UP. 2011. The role of iron in Libby amphibole-induced toxicity. Inhal Toxicol.
   Web of Science ®Google Scholar
• Smartt AM, Brezinski M, Trapkus M, Gardner D, Putnam EA. 2010. Collagen accumulation over time in the murine lung after exposure to crocidolite asbestos or Libby amphibole. Environ Toxicol 25:68–76.
   PubMed Web of Science ®Google Scholar
• Sullivan PA. 2007. Vermiculite, respiratory disease, and asbestos exposure in Libby, Montana: update of a cohort mortality study. Environ Health Perspect 115:579–585.
   PubMed Web of Science ®Google Scholar
• US EPA. 2010. Particle size distribution data for Libby amphibole structures observed in air at the Libby asbestos Superfund site. Superfund Records Center, US EPA Region 8, Denver, CO.
   Google Scholar
• Wallenborn JG, Kovalcik KD, McGee JK, Landis MS, Kodavanti UP. 2009. Systemic translocation of (70)zinc: kinetics following intratracheal instillation in rats. Toxicol Appl Pharmacol 234:25–32.
   PubMed Web of Science ®Google Scholar
• Webber JS, Blake DJ, Ward TJ, Pfau JC. 2008. Separation and characterization of respirable amphibole fibers from Libby, Montana. Inhal Toxicol 20:733–740.
   PubMed Web of Science ®Google Scholar
• Xie XM, Cao X, Chen MF, Zhou YC, Chen XB, Jiang HY. 2008. Effect of chronic iron overload on atherosclerosis lesion in apolipoprotein E knockout mice. Zhong Nan Da Xue Xue Bao.Yi Xue Ban 33:57–62.
   PubMedGoogle Scholar
• Yasuda T, Funakubo A, Fukui Y. 2002. An investigation of blood damage induced by static pressure during shear-rate conditions. Artif Organs 26:27–31.
   PubMed Web of Science ®Google Scholar