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Inhalation Toxicology
International Forum for Respiratory Research
Volume 24, 2012 - Issue 3
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Research Article

Alteration of peripheral blood monocyte gene expression in humans following diesel exhaust inhalation

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Pages 172-181 | Received 07 Sep 2011, Accepted 03 Jan 2012, Published online: 27 Feb 2012

References

  • Brook RD. 2008. Cardiovascular effects of air pollution. Clin Sci 115:175–187.
  • Carlsten C, Kaufman JD, Peretz A, Trenga CA, Sheppard L, Sullivan JH. 2007. Coagulation markers in healthy human subjects exposed to diesel exhaust. Thromb Res 120:849–855.
  • Donaldson K, Tran L, Jimenez LA, Duffin R, Newby DE, Mills N, MacNee W, Stone V. 2005. Combustion-derived nanoparticles: a review of their toxicology following inhalation exposure. Part Fibre Toxicol 2:10.
  • Dreger H, Westphal K, Weller A, Baumann G, Stangl V, Meiners S, Stangl K. 2009. Nrf2-dependent upregulation of antioxidative enzymes: a novel pathway for proteasome inhibitor-mediated cardioprotection. Cardiovasc Res 83:354–361.
  • Elder A, Gelein R, Finkelstein J, Phipps R, Frampton M, Utell M, Kittelson DB, Watts WF, Hopke P, Jeong CH, Kim E, Liu W, Zhao W, Zhuo L, Vincent R, Kumarathasan P, Oberdörster G. 2004. On-road exposure to highway aerosols. 2. Exposures of aged, compromised rats. Inhal Toxicol 16 Suppl 1:41–53.
  • Fujii T, Hayashi S, Hogg JC, Mukae H, Suwa T, Goto Y, Vincent R, van Eeden SF. 2002. Interaction of alveolar macrophages and airway epithelial cells following exposure to particulate matter produces mediators that stimulate the bone marrow. Am J Respir Cell Mol Biol 27:34–41.
  • Gandhi S, Pettit AP, Ohman-Strickland P, Gow A, Zhang J, Lauer E, Kipen HM. 2009. Two methods for measurement of acute changes in endothelial function following diesel exhaust inhalation. Am J Respir Crit Care Med 179:A3164.
  • Goto Y, Ishii H, Hogg JC, Shih CH, Yatera K, Vincent R, van Eeden SF. 2004. Particulate matter air pollution stimulates monocyte release from the bone marrow. Am J Respir Crit Care Med 170:891–897.
  • Huang YC, Schmitt M, Yang Z, Que LG, Stewart JC, Frampton MW, Devlin RB. 2010. Gene expression profile in circulating mononuclear cells after exposure to ultrafine carbon particles. Inhal Toxicol 22:835–846.
  • Jacobs L, Emmerechts J, Mathieu C, Hoylaerts MF, Fierens F, Hoet PH, Nemery B, Nawrot TS. 2010. Air pollution related prothrombotic changes in persons with diabetes. Environ Health Perspect 118:191–196.
  • Kipen HM, Gandhi S, Rich DQ, Ohman-Strickland P, Laumbach R, Fan ZH, Chen L, Laskin DL, Zhang J, Madura K. 2011. Acute decreases in proteasome pathway activity after inhalation of fresh diesel exhaust or secondary organic aerosol. Environ Health Perspect 119:658–663.
  • Kooter I, Pennings J, Opperhuizen A, Cassee F. 2005. Gene expression pattern in spontaneously hypertensive rats exposed to urban particulate matter (EHC-93). Inhal Toxicol 17:53–65.
  • Laumbach RJ, Kipen HM, Kelly-McNeil K, Zhang J, Zhang L, Lioy PJ, Ohman-Strickland P, Gong J, Kusnecov A, Fiedler N.2011. Sickness response symptoms among healthy volunteers after controlled exposures to diesel exhaust and psychological stress. Environ Health Perspect 119:945–950.
  • Laumbach R, Tong J, Zhang L, Ohman-Strickland P, Stern A, Fiedler N, Kipen H, Kelly-McNeil K, Lioy P, Zhang J. 2009. Quantification of 1-aminopyrene in human urine after a controlled exposure to diesel exhaust. J Environ Monit 11:153–159.
  • Li XY, Gilmour PS, Donaldson K, MacNee W. 1996. Free radical activity and pro-inflammatory effects of particulate air pollution (PM10) in vivo and in vitro. Thorax 51:1216–1222.
  • Liu CW, Li X, Thompson D, Wooding K, Chang TL, Tang Z, Yu H, Thomas PJ, DeMartino GN. 2006. ATP binding and ATP hydrolysis play distinct roles in the function of 26S proteasome. Mol Cell 24:39–50.
  • Lucking AJ, Lundback M, Mills NL, Faratian D, Barath SL, Pourazar J, Cassee FR, Donaldson K, Boon NA, Badimon JJ, Sandstrom T, Blomberg A, Newby DE. 2008. Diesel exhaust inhalation increases thrombus formation in man. Eur Heart J 29:3043–3051.
  • Meiners S, Ludwig A, Lorenz M, Dreger H, Baumann G, Stangl V, Stangl K. 2006. Nontoxic proteasome inhibition activates a protective antioxidant defense response in endothelial cells. Free Radic Biol Med 40:2232–2241.
  • Miller MR, Borthwick SJ, Shaw CA, McLean SG, McClure D, Mills NL, Duffin R, Donaldson K, Megson IL, Hadoke PW, Newby DE. 2009. Direct impairment of vascular function by diesel exhaust particulate through reduced bioavailability of endothelium-derived nitric oxide induced by superoxide free radicals. Environ Health Perspect 117:611–616.
  • Mills NL, Donaldson K, Hadoke PW, Boon NA, MacNee W, Cassee FR, Sandström T, Blomberg A, Newby DE. 2009. Adverse cardiovascular effects of air pollution. Nat Clin Pract Cardiovasc Med 6:36–44.
  • Nel AE, Diaz-Sanchez D, Li N. 2001. The role of particulate pollutants in pulmonary inflammation and asthma: evidence for the involvement of organic chemicals and oxidative stress. Curr Opin Pulm Med 7:20–26.
  • Obin M, Shang F, Gong X, Handelman G, Blumberg J, Taylor A. 1998. Redox regulation of ubiquitin-conjugating enzymes: mechanistic insights using the thiol-specific oxidant diamide. FASEB J 12:561–569.
  • Peretz A, Peck EC, Bammler TK, Beyer RP, Sullivan JH, Trenga CA, Srinouanprachnah S, Farin FM, Kaufman JD. 2007. Diesel exhaust inhalation and assessment of peripheral blood mononuclear cell gene transcription effects: an exploratory study of healthy human volunteers. Inhal Toxicol 19:1107–1119.
  • Peretz A, Sullivan JH, Leotta DF, Trenga CA, Sands FN, Allen J, Carlsten C, Wilkinson CW, Gill EA, Kaufman JD. 2008. Diesel exhaust inhalation elicits acute vasoconstriction in vivo. Environ Health Perspect 116:937–942.
  • Pope CA 3rd, Burnett RT, Thurston GD, Thun MJ, Calle EE, Krewski D, Godleski JJ. 2004. Cardiovascular mortality and long-term exposure to particulate air pollution: epidemiological evidence of general pathophysiological pathways of disease. Circulation 109:71–77.
  • Reed MD, Gigliotti AP, McDonald JD, Seagrave JC, Seilkop SK, Mauderly JL. 2004. Health effects of subchronic exposure to environmental levels of diesel exhaust. Inhal Toxicol 16:177–193.
  • Salomons FA, Menéndez-Benito V, Böttcher C, McCray BA, Taylor JP, Dantuma NP. 2009. Selective accumulation of aggregation-prone proteasome substrates in response to proteotoxic stress. Mol Cell Biol 29:1774–1785.
  • Salvi S, Blomberg A, Rudell B, Kelly F, Sandström T, Holgate ST, Frew A. 1999. Acute inflammatory responses in the airways and peripheral blood after short-term exposure to diesel exhaust in healthy human volunteers. Am J Respir Crit Care Med 159:702–709.
  • Seaton A, MacNee W, Donaldson K, Godden D. 1995. Particulate air pollution and acute health effects. Lancet 345:176–178.
  • Smith DM, Kafri G, Cheng Y, Ng D, Walz T, Goldberg AL. 2005. ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins. Mol Cell 20:687–698.
  • Stangl V, Lorenz M, Meiners S, Ludwig A, Bartsch C, Moobed M, Vietzke A, Kinkel HT, Baumann G, Stangl K. 2004. Long-term up-regulation of eNOS and improvement of endothelial function by inhibition of the ubiquitin-proteasome pathway. FASEB J 18:272–279.
  • Sunil VR, Patel KJ, Mainelis G, Turpin BJ, Ridgely S, Laumbach RJ, Kipen HM, Nazarenko Y, Veleeparambil M, Gow AJ, Laskin JD, Laskin DL. 2009. Pulmonary effects of inhaled diesel exhaust in aged mice. Toxicol Appl Pharmacol 241:283–293.

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