Pulmonary and cardiovascular responses of rats to inhalation of a commercial antimicrobial spray containing titanium dioxide nanoparticles

References

• Alarie Y. 1981. Toxicological evaluation of airborne chemical irritants and allergens using respiratory reflex reactions. In: Leong BKD, ed. Proceeding of inhalation toxicology and technology symposium. Ann Arbor: Ann Arbor Science Publisher, pp 207–231.
   Google Scholar
• Castranova V, Frazer DG, Manley LK, Dey RD. 2002. Pulmonary alterations associated with inhalation of occupational and environmental irritants. Int Immunopharmacol 2:163–172.
   PubMed Web of Science ®Google Scholar
• Chen BT, Afshari A, Stone S, Jackson M, Schwegler-Berry D, Frazer DG, Castranova V, Thomas TA. 2010. Nanoparticles-containing spray can aerosol: characterization, exposure assessment, and generator design. Inhal Toxicol 22:1072–1082.
   PubMed Web of Science ®Google Scholar
• Duffin R, Tran L, Brown D, Stone V, Donaldson K. 2007. Proinflammogenic effects of low-toxicity and metal nanoparticles in vivo and in vitro: highlighting the role of particle surface area and surface reactivity. Inhal Toxicol 19:849–856.
   PubMed Web of Science ®Google Scholar
• Ferin J, Oberdörster G, Penney DP. 1992. Pulmonary retention of ultrafine and fine particles in rats. Am J Respir Cell Mol Biol 6:535–542.
   PubMed Web of Science ®Google Scholar
• Krajnak K, Kan H, Waugh S, Miller GR, Johnson C, Roberts JR, Goldsmith WT, Jackson M, McKinney W, Frazer D, Kashon ML, Castranova V. 2011. Acute effects of COREXIT EC9500A on cardiovascular functions in rats. J Toxicol Environ Health Part A 74:1397–1404.
   PubMed Web of Science ®Google Scholar
• LeBlanc AJ, Cumpston JL, Chen BT, Frazer D, Castranova V, Nurkiewicz TR. 2009. Nanoparticle inhalation impairs endothelium-dependent vasodilation in subepicardial arterioles. J Toxicol Environ Health Part A 72:1576–1584.
   PubMed Web of Science ®Google Scholar
• McKinney W, Chen B, Frazer D. 2009. Computer controlled multi-walled carbon nanotube inhalation exposure system. Inhal Toxicol 21:1053–1061.
   PubMed Web of Science ®Google Scholar
• Mercer RR, Hubbs AF, Scabilloni JF, Wang L, Battelli LA, Friend S, Castranova V, Porter DW. 2011. Pulmonary fibrotic response to aspiration of multi-walled carbon nanotubes. Part Fibre Toxicol 8:21.
   PubMed Web of Science ®Google Scholar
• Nurkiewicz TR, Porter DW, Hubbs AF, Cumpston JL, Chen BT, Frazer DG, Castranova V. 2008. Nanoparticle inhalation augments particle-dependent systemic microvascular dysfunction. Part Fibre Toxicol 5:1.
   PubMed Web of Science ®Google Scholar
• Oberdorster G. 1996. Significance of particle parameters in the evaluation of exposure-dose-response relationships of inhaled particles. Inhal Toxicol 8 Suppl:73–89.
   PubMedGoogle Scholar
• Pennock BE, Cox CP, Rogers RM, Cain WA, Wells JH. 1979. A noninvasive technique for measurement of changes in specific airway resistance. J Appl Physiol 46:399–406.
   PubMed Web of Science ®Google Scholar
• Porter DW, Hubbs AF, Robinson VA, Battelli LA, Greskevitch M, Barger M, Landsittel D, Jones W, Castranova V. 2002. Comparative pulmonary toxicity of blasting sand and five substitute abrasive blasting agents. J Toxicol Environ Health Part A 65:1121–1140.
   PubMed Web of Science ®Google Scholar
• Porter DW, Hubbs AF, Baron PA, Millecchia LL, Wolfarth MG, Battelli LA, Schwegler-Berry DE, Beighley CM, Andrew ME, Castranova V. 2007. Pulmonary toxicity of Expancel microspheres in the rat. Toxicol Pathol 35:702–714.
   PubMed Web of Science ®Google Scholar
• Sager TM, Kommineni C, Castranova V. 2008. Pulmonary response to intratracheal instillation of ultrafine versus fine titanium dioxide: role of particle surface area. Part Fibre Toxicol 5:17.
   PubMed Web of Science ®Google Scholar
• Schaper M, Thompson RD, Alarie Y. 1985. A method to classify airborne chemicals which alter the normal ventilatory response induced by CO2. Toxicol Appl Pharmacol 79:332–341.
   PubMed Web of Science ®Google Scholar
• Rocco MC. 2004. Science and technology integration for increased human potential and societal outcomes. Ann NY Acad Sci 1013:1–6.
   Web of Science ®Google Scholar
• Shvedova AA, Kisin ER, Mercer R, Murray AR, Johnson VJ, Potapovich AI, Tyurina YY, Gorelik O, Arepalli S, Schwegler-Berry D, Hubbs AF, Antonini J, Evans DE, Ku BK, Ramsey D, Maynard A, Kagan VE, Castranova V, Baron P. 2005. Unusual inflammatory and fibrogenic pulmonary responses to single-walled carbon nanotubes in mice. Am J Physiol Lung Cell Mol Physiol 289:L698–L708.
   PubMed Web of Science ®Google Scholar
• Stone KC, Mercer RR, Gehr P, Stockstill B, Crapo JD. 1992. Allometric relationships of cell numbers and size in the mammalian lung. Am J Respir Cell Mol Biol 6:235–243.
   PubMed Web of Science ®Google Scholar
• Sweeney TD, Brain JD, Leavitt SA, Godleski JJ. 1987. Emphysema alters the deposition pattern of inhaled particles in hamsters. Am J Pathol 128:19–28.
   PubMed Web of Science ®Google Scholar