Publication Cover
Inhalation Toxicology
International Forum for Respiratory Research
Volume 24, 2012 - Issue 8
331
Views
49
CrossRef citations to date
0
Altmetric
Research Article

Local deposition fractions of ultrafine particles in a human nasal-sinus cavity CFD model

, &
Pages 492-505 | Received 28 Feb 2012, Accepted 14 May 2012, Published online: 02 Jul 2012

References

  • Auffan M, Rose J, Bottero JY, Lowry GV, Jolivet JP, Wiesner MR. 2009. Towards a definition of inorganic nanoparticles from an environmental, health and safety perspective. Nat Nanotechnol 4:634–641.
  • Calderón-Garcidueñas L, Delgado R, Calderón-Garcidueñas A, Meneses A, Ruiz LM, De La Garza J, Acuna H, Villarreal-Calderón A, Raab-Traub N, Devlin R. 2000. Malignant neoplasms of the nasal cavity and paranasal sinuses: A series of 256 patients in Mexico City and Monterrey. Is air pollution the missing link? Otolaryngol Head Neck Surg 122:499–508.
  • Cheng K-H, Cheng Y-S, Yeh H-C, Swift DL. 1995. Deposition of ultrafine aerosols in the head airways during natural breathing and during simulated breath holding using replicate human upper airway casts. Aerosol Sci Tech 23:465–474.
  • Cheng KH, Cheng YS, Yeh HC, Guilmette A, Simpson SQ, Yang YH, Swift DL. 1996a. In-vivo measurements of nasal airway dimensions and ultrafine aerosol deposition in the human nasal and oral airways. J Aerosol Sci 27:785–801.
  • Cheng YS, Yeh HC, Guilmette RA, Simpson SQ, Cheng KH, Swift DL. 1996b. Nasal deposition of ultrafine particles in human volunteers and its relationship to airway geometry. Aerosol Sci Tech 25:274–291.
  • Cheng YS, Holmes TD, Gao J, Guilmette RA, Li S, Surakitbanharn Y, Rowlings C. 2001. Characterization of nasal spray pumps and deposition pattern in a replica of the human nasal airway. J Aerosol Med 14:267–280.
  • Churchill SE, Shackelford LL, Georgi JN, Black MT. 2004. Morphological variation and airflow dynamics in the human nose. Am J Hum Biol 16:625–638.
  • Doorly DJ, Taylor DJ, Gambaruto AM, Schroter RC, Tolley N. 2008. Nasal architecture: form and flow. Phil Trans Math Phys Eng Sci 366:3225–3246.
  • Elwood JM. 1981. Wood exposure and smoking: Association with cancer of the nasal cavity and paranasal sinuses in British Columbia. Can Med Assoc J 124:1573–1577.
  • Garcia GJ, Bailie N, Martins DA, Kimbell JS. 2007. Atrophic rhinitis: A CFD study of air conditioning in the nasal cavity. J Appl Physiol 103:1082–1092.
  • Hahn I, Scherer PW, Mozell MM. 1993. Velocity profiles measured for airflow through a large-scale model of the human nasal cavity. J Appl Physiol 75:2273–2287.
  • Halperin WE, Goodman M, Stayner L, Elliott LJ, Keenlyside RA, Landrigan PJ. 1983. Nasal cancer in a worker exposed to formaldehyde. JAMA 249:510–512.
  • Hood CM, Schroter RC, Doorly DJ, Blenke EJ, Tolley NS. 2009. Computational modeling of flow and gas exchange in models of the human maxillary sinus. J Appl Physiol 107:1195–1203.
  • Ingham DB. 1975. Diffusion of aerosols from a stream flowing through a cylindrical tube. J Aerosol Sci 6:125–132.
  • Inthavong K, Tian ZF, Li HF, Tu JY, Yang W, Xue CL, Li CG. 2006. A numerical study of spray particle deposition in a human nasal cavity. Aerosol Sci Techn 40:1034–1045.
  • Inthavong K, Ge Q, Se CMK, Yang W, Tu JY. 2011a. Simulation of sprayed particle deposition in a human nasal cavity including a nasal spray device. J Aerosol Sci 42:100–113.
  • Inthavong K, Zhang K, Tu J. 2011b. Numerical modelling of nanoparticle deposition in the nasal cavity and the tracheobronchial airway. Comput Methods Biomech Biomed Engin 14:633–643.
  • Keir J. 2009. Why do we have paranasal sinuses? J Laryngol Otol 123:4–8.
  • Kelly JT, Prasad AK, Wexler AS. 2000. Detailed flow patterns in the nasal cavity. J Appl Physiol 89:323–337.
  • Kelly J, Asgharian B, Kimbell J, Wong B. 2004. Particle deposition in human nasal airway replicas manufactured by different methods. Part II: Ultrafine particles. Aerosol Sci Tech 38:1072–1079.
  • Lindemann J, Brambs HJ, Keck T, Wiesmiller KM, Rettinger G, Pless D. 2005. Numerical simulation of intranasal airflow after radical sinus surgery. Am J Otolaryngol 26:175–180.
  • Longest PW, Xi J. 2007a. Computational investigation of particle inertia effects on submicron aerosol deposition in the respiratory tract. J Aerosol Sci 38:111–130.
  • Longest PW, Xi J. 2007b. Effectiveness of direct Lagrangian tracking models for simulating nanoparticle deposition in the upper airways. Aerosol Sci Tech 41:380–397.
  • Ounis H, Ahmadi G, McLaughlin JB. 1991. Brownian diffusion of submicrometer particles in the viscous sublayer. J Colloid Interface Sci 143:266–277.
  • Pleis JR, Lucas JW, Ward BW. 2009. Summary health statistics for U.S. adults: National Health Interview Survey, 2008. Vital Health Stat 10:1–157.
  • Robert GH. 2001. Forced inspiratory nasal flow–volume curves: A simple test of nasal airflow. Mayo Clin Proc 76:990–994.
  • Schroeter JD, Kimbell JS, Asgharian B. 2006a. Analysis of particle deposition in the turbinate and olfactory regions using a human nasal computational fluid dynamics model. J Aerosol Med 19:301–313.
  • Schroeter JD, Kimbell JS, Asgharian B. 2006b. Analysis of particle deposition in the turbinate and olfactory regions using a human nasal computational fluid dynamics model. J Aerosol Med 19:301–313.
  • Schroeter JD, Garcia GJ, Kimbell JS. 2011. Effects of Surface Smoothness on Inertial Particle Deposition in Human Nasal Models. J Aerosol Sci 42:52–63.
  • Shi H, Kleinstreuer C, Zhang Z. 2008. Dilute suspension flow with nanoparticle deposition in a representative nasal airway model. Phys Fluid 20:1–23.
  • Slavin RG. 1988. Sinusitis in adults and its relation to allergic rhinitis, asthma, and nasal polyps. J Allergy Clin Immunol 82:950–956.
  • Subramaniam RP, Richardson RB, Morgan KT, Kimbell JS, Guilmette RA. 1998. Computational fluid dynamics simulations of inspiratory airflow in the human nose and nasopharynx. Inhal Toxicol 10:91–120.
  • Swift DL, Proctor DF. 1977. Access of air to the respiratory tract. In: Brain JD, Proctor DF, Reid LM, eds. Respiratory Defense Mechanism. New York: Marcel Dekker, 63–93.
  • Wang J, Flagan RC, Seinfeld JH. 2002. Diffusional losses in particle sampling systems containing bends and elbows. J Aerosol Sci 33:843–857.
  • Wang SM, Inthavong K, Wen J, Tu JY, Xue CL. 2009. Comparison of micron- and nanoparticle deposition patterns in a realistic human nasal cavity. Respir Physiol Neurobiol 166:142–151.
  • Wen J, Inthavong K, Tu J, Wang S. 2008. Numerical simulations for detailed airflow dynamics in a human nasal cavity. Respir Physiol Neurobiol 161:125–135.
  • Xi J, Longest PW. 2008. Numerical predictions of submicrometer aerosol deposition in the nasal cavity using a novel drift flux approach. Int J Heat and Mass Tran 51:5562–5577.
  • Xiong GX, Zhan JM, Jiang HY, Li JF, Rong LW, Xu G, Xu G. 2008. Computational fluid dynamics simulation of airflow in the normal nasal cavity and paranasal sinuses. Am J Rhinol 22:477–482.
  • Zamankhan P, Ahmadi G, Wang Z, Hopke PH, Cheng YS, Su WC, Leonard D. 2006. Airflow and deposition of nanoparticles in a human nasal cavity. Aerosol Science Technol 40:463–476.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.