References
- Anjilvel S, Asgharian B. (1995). A multiple-path model of particle deposition in the rat lung. Fundam Appl Toxicol 28:41–50
- Baran D, Dachy A, Klastersky J. (1975). Concentration of gentamicin in bronchial secretions of children with cystic fibrosis or tracheostomy. Intern J Clin Pharmacal 12:336–41
- Bide RW, Armour SJ, Yee E. (2000). Allometric respiration/body mass data for animals to be used for estimates of inhalation toxicity to young adult humans. J Appl Toxicol 20:273–90
- Bregman CL, Adler RR, Morton DG, et al. (2003). Recommended tissue list for histopathologic examination in repeat-dose toxicity and carcinogenicity studies: a proposal of the society of toxicologic pathology (STP). Toxicol Pathol 2:252–3
- Burger GT, Renne RA, Sagartz JW, et al. (1989). Histologic changes in respiratory tract induced by inhalation of xenobiotics: physiologic adaptation or toxicity? Toxicol Appl Pharmacol 101:521–42
- Cannon WC, Blanton EF, McDonald KE. (1983). The flow past chamber: an improved nose-only exposure system for rodents. Am Ind Hyg Assoc J 44:923–8
- Crowther Labiris NR, Holbrook AM, Chrystyn H, et al. (1999). Dry powder versus intravenous and nebulized gentamicin in cystic fibrosis and bronchiectasis. a pilot study. Am J Respir Crit Care Med 160:1711–16
- FDA. (1997). Summary basis of approval for tobramycin for inhalation. NDA 50753
- Gellar DE, Weers J, Heurerding, S. (2011). Development of an inhaled dry-powder formulation of tobramycin using PulmoSphere™ technology. J Aerosol Med Pulm Drug Deliv 24:175–82
- Gentamicin Sulfate Injection. (2011). Human prescription drug label. Available from: http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=2fcd1c1f-bd01-42c7-2c89-5eee2fe7055b [last accessed September 2012]
- Gilbert DN, Plamp C, Starr P, et al. (1978). Comparative nephrotoxicity of gentamicin and tobramycin in rats. Antimicrob Agents Chemother 13:34–40
- Hall CB. (1989). Aerosolized treatment of acute pulmonary infections. J Aerosol Med 2:221–31
- Høiby N. (2011). Recent advances in the treatment of Pseudomonas aeruginosa infections in cystic fibrosis. BMC Med 9:32
- Ilowite JS, Gorvoy JD, Smaldone GC. (1987). Quantitative deposition of aerosolized gentamicin in cystic fibrosis. Am Rev Respir Dis 136:1445–9
- Ishii R, Horie M, Chan W, MacNeil J. (2008). Multi-residue quantitation of aminoglycoside antibiotics in kidney and meat by liquid chromatography with tandem mass spectrometry. Food Addit Contam Part A Chem Anal Control Expo Risk Assess 25:1509–19
- Klastersky J, Geunign C, Mouawad E, Daneau, D. (1972). Endotracheal gentamicin in bronchial infection in patients with tracheostomy. Chest 61:117–20
- Lewis DJ. (1991). Morphological assessment of pathological changes within the rat larynx. Toxicol Pathol 19:352–7
- Luft FC, Kleit SA. (1974). Renal parenchymal accumulation of aminoglycoside antibiotics in rats. J Infect Dis 130:656–9
- Mauderly JL. (1972). Steady-state carbon monoxide-diffusing capacity of unanesthetized beagle dogs. Am J Vet Res 33:1485–91
- Mauderly JL. (1979). Effect of age on pulmonary structure and function of immature and adult animals and man. Fed Proc 38:173–7
- Murray MP, Govan JR, Doherty CJ, et al. (2010). A randomized controlled trial of nebulized gentamicin in non-cystic fibrosis bronchiectasis. Am J Respir Crit Care Med 183:491–9
- Naesens R, Vlieghe E, Verbrugghe W, et al. (2011). A retrospective observational study on the efficacy of colistin by inhalation as compared to parenteral administration for the treatment of nosocomial pneumonia associated with multidrug-resistant Pseudomonas aeruginosa. BMC Infect Dis 11:317
- National Institute for Public Health and the Environment, RIVM. (2002). Multiple path particle dosimetry model (MPPD v 1.0): a model for human and rat airway particle dosimetry. RIVA Report 65001(0030). Bilthoven, The Netherlands
- Newhouse MT, Hirst PH, Duddu SP, et al. (2003). Inhalation of a dry powder tobramycin PulmoSphere formulation in healthy volunteers. Chest 124:360–6
- Palmer LB, Smaldone GC, Simon SR, et al. (1998). Aerosolized antibiotics in mechanically ventilated patients: delivery and response. Critical Care Med 26:31–9
- Prober CG, Walson PD, Jones J; the Committee on Infectious Diseases and Committee on Drugs. (2000). Precautions regarding the use of aerosolized antibiotics. Pediatrics 106:89–95
- Rotstein C, Evans G, Born A, et al. (2008). Clinical practice guidelines for hospital-acquired pneumonia and ventilator-associated pneumonia in adults. Can J Infect Dis Med Microbiol 19:19–53
- Roy CJ, Sivasubramani SK, Dutta NK, et al. (2012). Aerosolized gentamicin reduces the burden of tuberculosis in a murine model. Antimicrob Agents Chemother 56:883–6
- Schentag JJ, Cumbo TJ, Jusko WJ, Plant ME. (1978). Gentamicin tissue accumulation and nephrotoxic reactions. J Am Med Assoc 240:2067–9
- Schentag JJ, Plaut ME, Cerra FB. (1981). Comparative nephrotoxicity of gentamicin and tobramycin: pharmacokinetic and clinical studies in 201 patients. Antimicro Agents Chemother 19:859–66
- Schlesinger RB. (1985). Comparative deposition of inhaled aerosols in experimental animals and humans: a review. J Toxicol Environ Health 15:197–214
- Schuster A, Haliburn C, Döring G, Goldman MH. (2013). Safety, efficacy and convenience of colistimethate sodium dry powder for inhalation (Colobreathe DPI) in patients with cystic fibrosis: a randomised study. Thorax 68:344–50
- Talton JD, Eppler B, Kirk JF, et al. (2010). Inhaled gentamicin: making a dry powder formulation to satisfy a clinical need. Proc Resp Drug Del 2:63–72
- Tomazewski JE. (2004). Multi-species toxicology approaches for oncology drugs: the US perspective. Eur J Cancer 40:907–13
- Twiss J, Byrnes C, Johnson R, Holland D. (2005). Nebulised gentamicin-suitable for childhood bronchiectasis. Int J Pharm 13:295:113–19
- Tyler WS, Julian MD. (1992). Gross and subgross anatomy of lungs, pleura, connective tissue septa, distal airways, and structural units. In: Parent RA. (ed.) Treatise on pulmonary biology: comparative biology of the normal lung. Boca Raton: CRC Press, 37–48
- Weinstein MJ, Luedemann GM, Oden EM, et al. (1963). Gentamicin, a new antibiotic complex from micromonospora. J Med Chem 6:463–4
- Zhanel GG, Lawson CD, Zelenitsky S, et al. (2012). Comparison of the next-generation aminoglycoside plazomicin to gentamicin, tobramycin and amikacin. Expert Rev Anti Infect Ther 10:459–73