References
- Aghai ZH, Kumar S, Farhath S, et al. (2006). Dexamethasone suppresses expression of Nuclear Factor-kappaB in the cells of tracheobronchial lavage fluid in premature neonates with respiratory distress. Pediatr Res 59:811–15
- Arcaroli J, Yum HK, Kupfner J, et al. (2001). Role of p38 MAP kinase in the development of acute lung injury. Clin Immunol 101:211–19
- Bhatia M, Moochhala S. (2004). Role of inflammatory mediators in the pathophysiology of acute respiratory distress syndrome. J Pathol 202:145–56
- Chi G, Wei M, Xie X, et al. (2013). Suppression of MAPK and NF-kappaB pathways by limonene contributes to attenuation of lipopolysaccharide-induced inflammatory responses in acute lung injury. Inflammation 36:501–11
- Dechert RE, Haas CF, Ostwani W. (2012). Current knowledge of acute lung injury and acute respiratory distress syndrome. Crit Care Nurs Clin North Am 24:377–401
- Dinarello CA. (2000). Proinflammatory cytokines. Chest 118:503–8
- Everhart MB, Han W, Sherrill TP, et al. (2006). Duration and intensity of NF-kappaB activity determine the severity of endotoxin-induced acute lung injury. J Immunol 176:4995–5005
- Han W, Joo M, Everhart MB, et al. (2009). Myeloid cells control termination of lung inflammation through the NF-kappaB pathway. Am J Physiol Lung Cell Mol Physiol 296:L320–7
- Hansen TM, Singh H, Tahir TA, Brindle NP. (2010). Effects of angiopoietins-1 and -2 on the receptor tyrosine kinase Tie2 are differentially regulated at the endothelial cell surface. Cell Signal 22:527–32
- Hodge S, Hodge G, Flower R, et al. (2002). Up-regulation of production of TGF-beta and IL-4 and down-regulation of IL-6 by apoptotic human bronchial epithelial cells. Immunol Cell Biol 80:537–43
- Huaux F, Liu T, McGarry B, et al. (2003). Dual roles of IL-4 in lung injury and fibrosis. J Immunol 170:2083–92
- Jenkins RG, McAnulty RJ, Hart SL, Laurent GJ. (2003). Pulmonary gene therapy. Realistic hope for the future, or false dawn in the promised land? Monaldi Arch Chest Dis 59:17–24
- Johnson GL, Lapadat R. (2002). Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 298:1911–12
- Kaminska B, Gozdz A, Zawadzka M, et al. (2009). MAPK signal transduction underlying brain inflammation and gliosis as therapeutic target. Anat Rec (Hoboken) 292:1902–13
- Kim HJ, Lee HS, Chong YH, Kang JL. (2006). p38 Mitogen-activated protein kinase up-regulates LPS-induced NF-kappaB activation in the development of lung injury and RAW 264.7 macrophages. Toxicology 225:36–47
- Kuldo JM, Westra J, Asgeirsdottir SA, et al. (2005). Differential effects of NF-{kappa}B and p38 MAPK inhibitors and combinations thereof on TNF-{alpha}- and IL-1{beta}-induced proinflammatory status of endothelial cells in vitro. Am J Physiol Cell Physiol 289:C1229–39
- Kweon SM, Wang B, Rixter D, et al. (2006). Synergistic activation of NF-kappaB by nontypeable H. influenzae and S. pneumoniae is mediated by CK2, IKKbeta-IkappaBalpha, and p38 MAPK. Biochem Biophys Res Commun 351:368–75
- Liu S, Feng G, Wang GL, Liu GJ. (2008). p38MAPK inhibition attenuates LPS-induced acute lung injury involvement of NF-kappaB pathway. Eur J Pharmacol 584:159–65
- Lucas R, Verin AD, Black SM, Catravas JD. (2009). Regulators of endothelial and epithelial barrier integrity and function in acute lung injury. Biochem Pharmacol 77:1763–72
- Neagoe PE, Dumas E, Hajjar F, Sirois MG. (2012). Angiopoietin-1 but not angiopoietin-2 induces IL-8 synthesis and release by human neutrophils. J Cell Physiol 227:3099–110
- Oeckinghaus A, Ghosh S. (2009). The NF-kappaB family of transcription factors and its regulation. Cold Spring Harb Perspect Biol 1:a000034
- Park GY, Christman JW. (2006). Nuclear factor kappa B is a promising therapeutic target in inflammatory lung disease. Curr Drug Targets 7:661–8
- Pearson G, Robinson F, Beers Gibson T, et al. (2001). Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev 22:153–83
- Sandhu R, Teichert-Kuliszewska K, Nag S, et al. (2004). Reciprocal regulation of angiopoietin-1 and angiopoietin-2 following myocardial infarction in the rat. Cardiovasc Res 64:115–24
- Sciuto AM. (1998). Assessment of early acute lung injury in rodents exposed to phosgene. Arch Toxicol 72:283–8
- Sciuto AM, Clapp DL, Hess ZA, Moran TS. (2003). The temporal profile of cytokines in the bronchoalveolar lavage fluid in mice exposed to the industrial gas phosgene. Inhal Toxicol 15:687–700
- Sciuto AM, Stotts RR, Hurt HH. (1996). Efficacy of ibuprofen and pentoxifylline in the treatment of phosgene-induced acute lung injury. J Appl Toxicol 16:381–4
- Seok SH, Heo JI, Hwang JH, et al. (2013). Angiopoietin-1 elicits pro-inflammatory responses in monocytes and differentiating macrophages. Mol Cells 35:550–6
- Shen J, Gan Z, Zhao J, et al. (2012). Ulinastatin reduces pathogenesis of phosgene-induced acute lung injury in rats. Toxicol Ind Health Oct 16: [Epub ahead of print]. doi: 10.1177/0748233712463776
- Shen J, Wang J, Shao YR, et al. (2013). Adenovirus-delivered angiopoietin-1 treatment for phosgene-induced acute lung injury. Inhal Toxicol 25:272–9
- Su X, Ao L, Zou N, et al. (2008). Post-transcriptional regulation of TNF-induced expression of ICAM-1 and IL-8 in human lung microvascular endothelial cells: an obligatory role for the p38 MAPK-MK2 pathway dissociated with HSP27. Biochim Biophys Acta 1783:1623–31
- Suzuki M, Matsuse T, Isigatsubo Y. (2001). Gene therapy for lung diseases: development in the vector biology and novel concepts for gene therapy applications. Curr Mol Med 1:67–79
- Tamura DY, Moore EE, Johnson JL, et al. (1998). p38 mitogen-activated protein kinase inhibition attenuates intercellular adhesion molecule-1 up-regulation on human pulmonary microvascular endothelial cells. Surgery 124:403–8
- Thurston G, Rudge JS, Ioffe E, et al. (2000). Angiopoietin-1 protects the adult vasculature against plasma leakage. Nat Med 6:460–3
- Tsigkos S, Koutsilieris M, Papapetropoulos A. (2003). Angiopoietins in angiogenesis and beyond. Expert Opin Investig Drugs 12:933–41
- van der Heijden M, van Nieuw Amerongen GP, Chedamni S, et al. (2009). The angiopoietin-Tie2 system as a therapeutic target in sepsis and acute lung injury. Expert Opin Ther Targets 13:39–53
- Ware LB. (2005). Prognostic determinants of acute respiratory distress syndrome in adults: impact on clinical trial design. Crit Care Med 33:S217–22
- Wheeler AP, Bernard GR. (2007). Acute lung injury and the acute respiratory distress syndrome: a clinical review. Lancet 369:1553–64
- Xu YN, Zhang Z, Ma P, Zhang SH. (2011). Adenovirus-delivered angiopoietin 1 accelerates the resolution of inflammation of acute endotoxic lung injury in mice. Anesth Analg 112:1403–10
- Yeh CC, Kao SJ, Lin CC, et al. (2007). The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro. Life Sci 80:1821–31